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Meds A-Z

Velagliflozin Proline Monohydrate

Detailed information about Velagliflozin Proline Monohydrate

Official label facts Owner quick guide first Marketing clearly labeled
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Pet Owner Quick Guide

Start here: what this medicine is for, what it does, and when it's usually needed.

Usually used for:

Use this medication only when your veterinarian confirms it matches your pet's condition.

What it does:

Use this medication only when your veterinarian confirms it matches your pet's condition.

When it's needed:

Use this medication only when your veterinarian confirms it matches your pet's condition.

Commonly reported reactions:

  • (1 reports)
  • (1 reports)
  • (1 reports)

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
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Velagliflozin Proline Monohydrate

Velagliflozin Proline Monohydrate

Drug type: Generic ingredient • Branded profile FDA branded products available

Species: Both

Manufacturer: Zoetis

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Zoetis
Form: No source yet
Identifiers:

No source yet.

Source metadata: No source yet.

Warnings / Contraindications

No contraindication summary is linked yet.

No owner-focused warning rows are linked yet.

Source metadata: No source yet.

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
18
Serious reports
0
Species represented
2
Most Reported Reactions
Reaction Cases Species Serious cases
1 Cat 0
1 Dog 0
1 Dog 0
1 Dog 0
1 Dog 0
1 Dog 0
1 Dog 0
1 Cat 0

Species coverage: Cat (20) Dog (12)

View detailed reaction table
Reaction Species Seriousness Frequency Reports
Dog Non-serious - 1
Cat Non-serious - 1
Dog Non-serious - 1
Cat Non-serious - 1
Dog Non-serious - 1
Cat Non-serious - 1
Cat Non-serious - 1
Cat Non-serious - 1
Cat Non-serious - 1
Cat Non-serious - 1
Cat Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Cat Non-serious - 1
Dog Unknown - -
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Dog Unknown - -
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Dog Unknown - -
Source metadata:

Storage & Handling

No storage/handling guidance is linked yet.

Source metadata: No source yet.

Documents

Official label facts are separated from secondary summaries.

Official documents: 3 • Secondary summaries: 0

Official label facts
Secondary summaries

No source yet.

Promotional Materials (Marketing)

This content is marketing material and not clinical guidance.

No marketing assets are linked yet.

No source yet.

Source metadata: No source yet.
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Technical appendix (vet reference)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 10:46 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 16, 2026, 11:03 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 12, 2026, 10:42 PM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Curated brands: Senvelgo from curated manufacturer/official sources
Manufacturer mapping: Boehringer Ingelheim Animal Health USA Inc.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 14 Cat 56 View
Case summaries: 11 (showing 8) View
openFDA reports are unverified and do not prove causation.

Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Blood in urine (1) Diarrhoea (1) Frequent urination (1) Haematemesis (1) Inappropriate urination (1) Ketosis (1) Lack of efficacy - NOS (1) Lethargy (see also Central nervous system depression in Neurological) (1) Leucocytosis NOS (1) Monocytosis (1) Neutrophilia (1) Peeling skin (1) Pica NOS (1) Polyuria (1) Reddening of the skin (1) Skin lump (1)

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

Data Sources & Revision History

Every non-trivial field is expected to include provenance and update timestamps.

Official 30 Clinical 5 Manufacturer 0 Marketing 0
Current Field Facts
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-02-16)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-02-15)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-02-14)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-02-13)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-02-12)
  • approval_reference: NADA 141-568 (Official, 2026-02-16)
  • approval_reference: NADA 141-568 (Official, 2026-02-15)
  • approval_reference: NADA 141-568 (Official, 2026-02-14)
  • approval_reference: NADA 141-568 (Official, 2026-02-13)
  • approval_reference: NADA 141-568 (Official, 2026-02-12)
  • brand_names: Senvelgo (Official, 2026-02-16)
  • brand_names: Senvelgo (Official, 2026-02-15)
  • brand_names: Senvelgo (Official, 2026-02-14)
  • brand_names: Senvelgo (Official, 2026-02-13)
  • brand_names: Senvelgo (Official, 2026-02-12)
  • drug_profile_type: branded (Official, 2026-02-16)
  • drug_profile_type: branded (Official, 2026-02-15)
  • drug_profile_type: branded (Official, 2026-02-14)
  • drug_profile_type: branded (Official, 2026-02-13)
  • drug_profile_type: branded (Official, 2026-02-12)
Recent Revisions
  • monitoring updated 2026-02-16 11:11 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-02-16 11:11 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-02-16 11:11 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-02-16 11:11 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-02-16 11:11 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-02-16 11:11 by curated_loader • Official FDA application reference for Senvelgo.
  • monitoring updated 2026-02-15 11:11 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-02-15 11:11 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-02-15 11:11 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-02-15 11:11 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-02-15 11:11 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-02-15 11:11 by curated_loader • Official FDA application reference for Senvelgo.
  • monitoring updated 2026-02-14 11:10 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-02-14 11:10 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-02-14 11:10 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-02-14 11:10 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-02-14 11:10 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-02-14 11:10 by curated_loader • Official FDA application reference for Senvelgo.
  • monitoring updated 2026-02-13 11:11 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-02-13 11:11 by curated_loader • Usage statement from FDA warning letter and approved-product context.

FDA Products & Applications (Animal Drugs @ FDA)

No linked FDA product applications are available for this ingredient yet.

Usage

No approved usage text is linked yet for this ingredient.

  • Catalog species: Both
  • Safety reports available: 11 openFDA case summaries (view)

Contraindications

No approved contraindication text is linked yet. Review FDA label highlights and openFDA safety reports before making treatment decisions.

Side Effects

No approved side-effect narrative is linked yet.

openFDA reaction signals are available for Dog 14 and Cat 56 (view top reported reactions).

Top Reported Reactions (openFDA)

Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).

Dog
Digestive
Diarrhea (20) Vomiting (18) Drooling (10)
Other
Overdose (31) Wound (5) Dermal cyst (3) Skin scab (3) Abrasion (2) Pica NOS (1) Pica NOS (1) Pica NOS (1) Pica NOS (1) Pica NOS (1) Pica NOS (1)
Cat
Digestive
Diarrhea (523) Vomiting (451) Loss of appetite (299) Vomiting (20) Vomiting (20) Vomiting (20) Vomiting (20) Vomiting (20) Vomiting (20) Diarrhea (18) Diarrhea (18) Diarrhea (18) Diarrhea (18) Diarrhea (18) Diarrhea (18) Loss of appetite (16) Loss of appetite (16) Loss of appetite (16) Loss of appetite (16) Loss of appetite (16) Loss of appetite (16)
Neurologic
Tiredness (lethargy) (419) Tiredness (lethargy) (18) Tiredness (lethargy) (18) Tiredness (lethargy) (17) Tiredness (lethargy) (17) Tiredness (lethargy) (16) Tiredness (lethargy) (15)
Effectiveness
Lack of efficacy - NOS (760) Lack of efficacy - NOS (34) Lack of efficacy - NOS (34) Lack of efficacy - NOS (34) Lack of efficacy - NOS (34) Lack of efficacy - NOS (32) Lack of efficacy - NOS (29)
Other
Ketosis (1088) Weight loss (710) Ketonuria (420) Ketosis (44) Ketosis (44) Ketosis (44) Ketosis (44) Ketosis (43) Ketosis (39) Weight loss (30) Weight loss (30) Weight loss (30) Weight loss (30) Weight loss (28) Weight loss (26) Ketonuria (15) Ketonuria (15) Ketonuria (15) Ketonuria (15) Ketonuria (15) Ketonuria (15)

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Cat, Russian, Male, 14 year, 5.307 kilogram • Drug: MSK, Solution, Oral, Dose: 1 Milligram per kilogram, Frequency: 1 per day • Reactions: Ketosis, Lack of efficacy - NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-056188
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 14.00 Year
  • Weight: 5.307 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Solution
  • Dose: 1 Milligram per kilogram
  • Frequency: 1 per day
Reactions Reported:
Ketosis Lack of efficacy - NOS
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Male, 19 year, 2.989 kilogram • Drug: MSK, Solution, Oral, Dose: 0.99 Milligram per kilogram, Frequency: 24 per hour • Reactions: Lack of efficacy - NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-056152
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 19.00 Year
  • Weight: 2.989 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Solution
  • Dose: 0.99 Milligram per kilogram
  • Frequency: 24 per hour
Reactions Reported:
Lack of efficacy - NOS
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Female, 10 year, 3.992 kilogram • Drug: MSK, Solution, Oral, Dose: 1.01 Milligram per kilogram, Frequency: 24 per hour • Reactions: Ketosis, Lack of efficacy - NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-056172
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 10.00 Year
  • Weight: 3.992 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Solution
  • Dose: 1.01 Milligram per kilogram
  • Frequency: 24 per hour
Reactions Reported:
Ketosis Lack of efficacy - NOS
Outcomes: Outcome Unknown

Cat, Cat (unknown), Unknown • Drug: MSK, Solution, Unknown • Reactions: Vomiting • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-056176
  • Serious AE: No
  • Treated For AE: No
  • Sex: Unknown
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Solution
Reactions Reported:
Vomiting
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Female, 10 year, 3.629 kilogram • Drug: MSK, Solution, Oral, Dose: 0.99 Milligram per kilogram, Frequency: 24 per hour • Reactions: Diarrhea, Vomiting, Tiredness (lethargy) • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-056191
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 10.00 Year
  • Weight: 3.629 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Solution
  • Dose: 0.99 Milligram per kilogram
  • Frequency: 24 per hour
Reactions Reported:
Diarrhea Vomiting Tiredness (lethargy)
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Female, 12 year, 4.354 kilogram • Drug: MSK, Solution, Parenteral, Dose: 1.03 Milligram per kilogram • Reactions: Vomiting, Haematemesis, Leucocytosis NOS, Neutrophilia, Monocytosis • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-056136
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 12.00 Year
  • Weight: 4.354 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Parenteral
  • Form: Solution
  • Dose: 1.03 Milligram per kilogram
Reactions Reported:
Vomiting Haematemesis Leucocytosis NOS Neutrophilia Monocytosis
Outcomes: Outcome Unknown

Dog, Dog (unknown), Unknown • Drug: MSK, Solution, Unknown • Reactions: Pica NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-052775
  • Serious AE: No
  • Treated For AE: No
  • Sex: Unknown
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Solution
Reactions Reported:
Pica NOS
Outcomes: Outcome Unknown

Dog, Alaskan Malamute, Female, 6 year, 41.277 kilogram • Drug: MSK, Solution, Unknown • Reactions: Polyuria, Inappropriate urination, Urinary tract infection • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-017805
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Female
  • Age: 6.00 Year
  • Weight: 41.277 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Solution
Reactions Reported:
Polyuria Inappropriate urination Urinary tract infection
Outcomes: Outcome Unknown

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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