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Maropitant

Detailed information about Maropitant

Official label facts Owner quick guide first Marketing clearly labeled
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Pet Owner Quick Guide

Start here: what this medicine is for, what it does, and when it's usually needed.

Usually used for:

For the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs.

What it does:

For the prevention of acute vomiting. For the prevention of vomiting due to motion sickness. For Prevention and Treatment of Acute Vomiting in Dogs: Dogs 2-4 Months of Age:

When it's needed:

For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterina...

Call your vet sooner if you notice:

  • For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian. CERENIA injectable solution should not be used interchangeably with CERENIA tablets for the prevention of vomiting due to motion sickness (8mg/kg). Federal law restricts this drug to use by or on the order of a licensed veterinarian. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.

Commonly reported reactions:

  • (2 reports)
  • (2 reports)
  • (2 reports)

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
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Maropitant

Maropitant

Drug type: Generic ingredient • Branded profile • FDA branded products available

Species: Both

Manufacturer: MSK

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: MSK
Form: Chewable Tablets, Injectable Solution, Liquid (Solution), Tablet
Identifiers:
ANADA: 200710 ANADA: 200747 ANADA: 200785 ANADA: 200833 NADA: 141262 NADA: 141263 NDC Package: 11695-7029-1 NDC Package: 11695-7029-2 NDC Package: 11695-7030-1 NDC Package: 11695-7030-2 NDC Package: 11695-7031-1 NDC Package: 11695-7031-2 NDC Package: 11695-7032-1 NDC Package: 11695-7032-2 NDC Package: 17033-004-01 NDC Package: 17033-006-04 NDC Package: 17033-006-60 NDC Package: 17033-007-04 NDC Package: 17033-007-60 NDC Package: 17033-008-04
Source metadata:

Warnings / Contraindications

For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian. CERENIA injectable solution should not be used interchangeably with CERENIA tablets for the prevention of vomiting due to motion sickness (8mg/kg). Federal law restricts this drug to use by or on the order of a licensed veterinarian. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.

  • High: For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian. CERENIA injectable solution should not be used interchangeably with CERENIA tablets for the prevention of vomiting due to motion sickness (8mg/kg). Federal law restricts this drug to use by or on the order of a licensed veterinarian. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
31
Species represented
2
Most Reported Reactions
Reaction Cases Species Serious cases
2 Cat, Dog 2
2 Cat, Dog 2
2 Cat, Dog 2
1 Dog 1
1 Cat 1
1 Dog 1
1 Cat 1
1 Dog 1

Species coverage: Dog (16) Cat (16)

View detailed reaction table
Reaction Species Seriousness Frequency Reports
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Non-serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Source metadata:

Storage & Handling

No storage/handling guidance is linked yet.

Source metadata: No source yet.

Documents

Official label facts are separated from secondary summaries.

Official documents: 16 • Secondary summaries: 0

Official label facts
Secondary summaries

No source yet.

Source metadata:

Promotional Materials (Marketing)

This content is marketing material and not clinical guidance.

No marketing assets are linked yet.

No source yet.

Source metadata: No source yet.
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Technical appendix (vet reference)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 16, 2026, 11:03 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:20 AM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: Cerenia® Injectable Solution Cerenia® Tablets Maropitant Citrate Maropitant Citrate Tablets
Case-reported brands (openFDA): MSK
Catalog species: Both • FDA-labeled species: Cat, Dog
Rx/OTC: RX
Form/route: Chewable Tablets, Injectable Solution, Liquid (Solution), Tablet • Intravenous, Oral, Subcutaneous
Applications: ANADA 200-833 • ANADA 200-710 • ANADA 200-785 • ANADA 200-747 • NADA 141-262 • NADA 141-263
NDC: Packages 11695-7029-1 11695-7029-2 11695-7030-1 11695-7030-2 11695-7031-1 11695-7031-2 • Products 11695 11695 11695 11695 11695 11695
Documents: 10 (FOI: 10) • SPL: 6 • Label highlights • Official documents
Safety (openFDA)
Top reactions: Dog 56 • Cat 56 • View
Case summaries: 10 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Explore
Linked using: Fda_Label (0.95), Fda_Label (0.95)
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian. CERENIA injectable solution should not be used interchangeably with CERENIA tablets for the prevention of vomiting due to motion sickness (8mg/kg). Federal law restricts this drug to use by or on the order of a licensed veterinarian. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens. (Contraindication, High)
Top reaction signals
Abdominal pain (1) Abnormal cytology (1) Abnormal radiograph finding (1) Abnormal tail posture (1) Abnormal ultrasound finding (1) Adipsia (1) Anaemia NOS (1) Anorexia (1) Anxiety (1) Application site crust (1) Application site erythema (1) Application site pain (1) Application site reaction NOS (1) Behavioural disorder NOS (1) Chewing disorder (1) Constipation (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
ANADA: 200710 ANADA: 200747 ANADA: 200785 ANADA: 200833 NADA: 141262 NADA: 141263 NDC Package: 11695-7029-1 NDC Package: 11695-7029-2 NDC Package: 11695-7030-1 NDC Package: 11695-7030-2 NDC Package: 11695-7031-1 NDC Package: 11695-7031-2 NDC Package: 11695-7032-1 NDC Package: 11695-7032-2 NDC Package: 17033-004-01 NDC Package: 17033-006-04 NDC Package: 17033-006-60 NDC Package: 17033-007-04 NDC Package: 17033-007-60 NDC Package: 17033-008-04 NDC Package: 17033-008-60 NDC Package: 17033-009-04 NDC Package: 17033-009-60 NDC Package: 46016-1470-0
Package NDC Product NDC Form / Route Status
11695-7029-1 11695 -
11695-7029-2 11695 -
11695-7030-1 11695 -
11695-7030-2 11695 -
11695-7031-1 11695 -
11695-7031-2 11695 -
11695-7032-1 11695 -
11695-7032-2 11695 -
17033-004-01 17033 -
17033-006-04 17033 -
17033-006-60 17033 -
17033-007-04 17033 -
17033-007-60 17033 -
17033-008-04 17033 -
17033-008-60 17033 -
17033-009-04 17033 -
17033-009-60 17033 -
46016-1470-0 46016 -
46016-3590-0 46016 -
46016-3592-0 46016 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

Data Sources & Revision History

Every non-trivial field is expected to include provenance and update timestamps.

Official 13 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For oral use in dogs only. Federal law restric… (Official, 2026-02-12)
  • side_effects: Top reported reactions (openFDA): Vomiting, Diarrhoea, Death by euthanasia, Lethargy (see also Central nervous system depression in 'Neurological'), Lethargy (… (Official, 2026-02-12)
  • usage: For the prevention of acute vomiting. For the prevention of vomiting due to motion sickness. For Prevention and Treatment of Acute Vomiting in Dogs: Dogs 2-4 M… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Maropitant Citrate Tablets
RX
Maropitant
Chewable Tablets • Oral
Label highlights
Official documents
Felix Pharmaceuticals Pvt. Ltd. ANADA 200-833 Approved Feb 2, 2026
Maropitant Citrate
RX
Maropitant
Injectable Solution • Intravenous, Subcutaneous
Label highlights
Official documents
Dechra Veterinary Products LLC ANADA 200-710 Approved Jan 5, 2026
Maropitant Citrate Tablets
RX
Maropitant
Tablet • Oral
Label highlights
Official documents
Felix Pharmaceuticals Pvt. Ltd. ANADA 200-785 Approved Jul 1, 2024
Maropitant Citrate
RX
Maropitant
Tablet • Oral
Label highlights
Official documents
ZYVET AH, Inc. ANADA 200-747 Approved Mar 31, 2023
Cerenia® Tablets
RX
Maropitant
Tablet • Oral
Label highlights
Official documents
Zoetis Inc. NADA 141-262 Approved Jan 31, 2019
Cerenia® Injectable Solution
RX
Maropitant
Liquid (Solution) • Subcutaneous, Intravenous
Label highlights
Official documents
Zoetis Inc. NADA 141-263 Approved Jun 1, 2016

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Composition / specifications
16 mg, 24 mg, 60 mg, or 160 mg of maropitant as maropitant citrate per tablet
Dogs
Indication

For the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs.

Dosage

For Prevention of Acute Vomiting in dogs 2 - 7 months of age: Administer Maropitant Citrate Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days.
For Prevention of Acute Vomiting in dogs 7 months of age and older: Administer Maropitant Citrate Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting.
For Prevention of Vomiting due to motion sickness in dogs 4 months of age and older: Administer Maropitant Citrate Tablets orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight once daily for up to 2 consecutive days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Composition / specifications
Each mL contains 10 mg of maropitant as maropitant citrate
Dogs
Indication

For the prevention and treatment of acute vomiting.

Dosage

Administer 1.0 mg per kilogram (mg/kg) of body weight by subcutaneous or intravenous injection once daily for up to 5 consecutive days.

Limitations
Cats
Indication

For the treatment of vomiting.

Dosage

Administer 1.0 mg/kg of body weight by subcutaneous or intravenous injection once daily for up to 5 consecutive days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Composition / specifications
16 mg, 24 mg, 60 mg, or 160 mg of maropitant citrate per tablet
Dogs
Indication

For the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs.

Dosage

For Prevention of Acute Vomiting in dogs 2 -7 months of age: Administer orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days.

For Prevention of Acute Vomiting in dogs 7 months of age and older: Administer orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting.

For Prevention of Vomiting due to motion sickness in dogs 4 months of age and older: Administer orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight once daily for up to 2 consecutive days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
16, 24, 60, or 160 mg of maropitant as maropitant citrate per tablet
Dogs (2-7 months of age)
Indication

For prevention of acute vomiting.

Dosage

Administer orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days.

Limitations
Dogs (7 months of age and older)
Indication

For prevention of acute vomiting.

Dosage

Administer orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting.

Limitations
Dogs (4 months of age and older)
Indication

For prevention of vomiting due to motion sickness.

Dosage

Administer orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight once daily for up to 2 consecutive days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
Each tablet contains 16, 24, 60, or 160 milligrams (mg) maropitant as maropitant citrate.
Dogs (7 Months of Age and Older)
Indication
For the prevention of acute vomiting.
Dosage
Administer CERENIA Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting.
Limitations
For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Dogs (4 Months of Age and Older)
Indication
For the prevention of vomiting due to motion sickness.
Dosage
Administer CERENIA Tablets orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight once daily for up to 2 consecutive days
Limitations
For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian. CERENIA injectable solution should not be used interchangeably with CERENIA tablets for the prevention of vomiting due to motion sickness (8mg/kg).
Dogs (2-7 Months)
Indication
For the prevention of acute vomiting.
Dosage
Administer CERENIA Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days
Limitations
For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied • Cat, No Use Class Stated Or Implied
Composition / specifications
Each milliliter of solution contains 10 milligrams (mg) maropitant as maropitant citrate.
Dogs (2-4 Months of Age)
Indication
For Prevention and Treatment of Acute Vomiting in Dogs: Dogs 2-4 Months of Age:
Dosage
Administer subcutaneously at 1 mg/kg (0.45 mg/lb) equal to 0.1 mL/kg (0.1 mL/2.2 lb) of body weight once daily for up to 5 consecutive days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.
Dogs (4 Months of Age and Older)
Indication
For Prevention of Vomiting in Dogs 4 months of Age and Older Caused by Emetogenic Medications or Chemotherapeutic Agents.
Dosage
Administer intravenously over 1-2 minutes or subcutaneously at 1 mg/kg (0.45 mg/lb) of body weight one time, 45-60 minutes prior to use of emetogenic medications or chemotherapeutic agents.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.
Indication
For Prevention and Treatment of Acute Vomiting in Dogs: Dogs 2-4 Months of Age:
Dosage
Administer intravenously over 1-2 minutes or subcutaneously at 1 mg/kg (0.45 mg/lb) equal to 0.1 mL/1 kg (1 mL/22 lb) of body weight once daily for up to 5 consecutive days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.
Cats (4 Months of Age and Older)
Indication
For Treatment of Vomiting in Cats 4 Months of Age and Older
Dosage
Administer intravenously over 1-2 minutes or subcutaneously at 1 mg/kg (0.45 mg/lb) equal to 0.1 mL/kg (0.1 mL/2.2 lb) of body weight once daily for up to 5 consecutive days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.

FDA page: Open in Animal Drugs @ FDA

Official Documents (FDA)

Direct links to FDA-hosted PDFs and SPL packages (when available).

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplement provides for the extension of the number of days of consecutive use from “5 days” to “until resolution of acute vomiting” for the prevention of acute vomiting in dogs 7 months and older.
  • Summary
    For the prevention of acute vomiting in dogs. For the prevention of vomiting due to motion sickness in dogs
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplement provides for the addition of the intravenous route of administration for dogs and cats, and clarifies the timing of administration prior to use of emetogenic medications in dogs.
  • Summary
    This supplement provides for the additional indication, “for the treatment of vomiting in cats.”
  • Summary
    This supplement provides for the decrease in the minimum age to “for use in dogs 8 weeks and older” for the prevention and treatment of acute vomiting in dogs.
  • Summary
    For the prevention and treatment of acute vomiting in dogs.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Usage

For the prevention of acute vomiting. For the prevention of vomiting due to motion sickness. For Prevention and Treatment of Acute Vomiting in Dogs: Dogs 2-4 Months of Age:

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian. CERENIA injectable solution should not be used interchangeably with CERENIA tablets for the prevention of vomiting due to motion sickness (8mg/kg). Federal law restricts this drug to use by or on the order of a licensed veterinarian. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.

Side Effects

No approved side-effect narrative is linked yet.

openFDA reaction signals are available for Dog 56 and Cat 56 (view top reported reactions).

Top Reported Reactions (openFDA)

Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).

Dog
Digestive
Vomiting (137) Diarrhea (96) Loss of appetite (64) Decreased appetite (3) Decreased appetite (3) Decreased appetite (3) Decreased appetite (3) Decreased appetite (3) Decreased appetite (3) Vomiting (2) Vomiting (2) Vomiting (2) Vomiting (2) Vomiting (2) Vomiting (2)
Neurologic
Tiredness (lethargy) (74) Tiredness (lethargy) (69) Tiredness (lethargy) (2) Tiredness (lethargy) (2) Tiredness (lethargy) (2) Tiredness (lethargy) (2) Tiredness (lethargy) (2) Tiredness (lethargy) (2)
Other
Death by euthanasia (83) Not eating (68) Elevated alanine aminotransferase (62) Death (2) Death (2) Death (2) Death (2) Death (2) Death (2) Death by euthanasia (2) Death by euthanasia (2) Death by euthanasia (2) Death by euthanasia (2) Death by euthanasia (2) Death by euthanasia (2) Medication error NOS (2) Medication error NOS (2) Medication error NOS (2) Medication error NOS (2) Medication error NOS (2) Medication error NOS (2) Musculoskeletal disorder NOS (2) Musculoskeletal disorder NOS (2) Musculoskeletal disorder NOS (2) Musculoskeletal disorder NOS (2) Musculoskeletal disorder NOS (2) Musculoskeletal disorder NOS (2) Abdominal pain (1) Abdominal pain (1) Abdominal pain (1) Abdominal pain (1) Abdominal pain (1) Abdominal pain (1)
Cat
Digestive
Vomiting (26) Drooling (19) Decreased appetite (16) Loss of appetite (16) Loss of appetite (2) Loss of appetite (2) Loss of appetite (2) Loss of appetite (2) Loss of appetite (2) Loss of appetite (2)
Neurologic
Tiredness (lethargy) (20)
Other
Death by euthanasia (32) Bradycardia (16) Not eating (16) Anaphylaxis (2) Anaphylaxis (2) Anaphylaxis (2) Anaphylaxis (2) Anaphylaxis (2) Anaphylaxis (2) Conjunctival oedema (2) Conjunctival oedema (2) Conjunctival oedema (2) Conjunctival oedema (2) Conjunctival oedema (2) Conjunctival oedema (2) Dysphoria (2) Dysphoria (2) Dysphoria (2) Dysphoria (2) Dysphoria (2) Dysphoria (2) Oedema NOS (2) Oedema NOS (2) Oedema NOS (2) Oedema NOS (2) Oedema NOS (2) Oedema NOS (2) Pharyngeal disorder (2) Pharyngeal disorder (2) Pharyngeal disorder (2) Pharyngeal disorder (2) Pharyngeal disorder (2) Pharyngeal disorder (2) Sedation (2) Sedation (2) Sedation (2) Sedation (2) Sedation (2) Sedation (2) Adipsia (1) Adipsia (1) Adipsia (1) Adipsia (1) Adipsia (1) Adipsia (1)

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Sheepdog - Old English (Bobtail), Male, 4 year, 37.8 kilogram • Drug: MSK, Subcutaneous • Reactions: Malaise, Gastric ulcer, Peritonitis, Fluid in abdomen NOS, Fluid in abdomen NOS… • Outcome: Euthanized

  • Report ID: DEU-USFDACVM-2025-DE-000039
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 4.00 Year
  • Weight: 37.800 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
Reactions Reported:
Malaise Gastric ulcer Peritonitis Fluid in abdomen NOS Fluid in abdomen NOS Abdominal pain Vomiting Abnormal ultrasound finding Death Hyperthermia
Outcomes: Euthanized

Dog, ['Shepherd Dog - German', 'Dog (unknown)'], Female, 7 year, 21 kilogram • Drug: MSK, Injection • Reactions: Decreased heart rate, Recovery prolonged • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-054709
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 7.00 Year
  • Weight: 21.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Form: Injection
Reactions Reported:
Decreased heart rate Recovery prolonged
Outcomes: Recovered/Normal

Cat, Domestic Shorthair, Male, 13 year, 4 kilogram • Drug: MSK, Oral • Reactions: Application site crust, Loss of appetite, Application site erythema, Application site pain, Application site reaction NOS • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-052859
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 13.00 Year
  • Weight: 4.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
Reactions Reported:
Application site crust Loss of appetite Application site erythema Application site pain Application site reaction NOS
Outcomes: Recovered/Normal

Cat, Domestic Shorthair, Male, 20 week, 3 kilogram • Drug: MSK, Unknown, Dose: 0.60 mL per animal • Reactions: Dysphoria, Sedation, Decreased blood urea nitrogen (BUN) or creatinine, Intentional misuse • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-053968
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 20.00 Week
  • Weight: 3.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Dose: 0.60 mL per animal
Reactions Reported:
Dysphoria Sedation Decreased blood urea nitrogen (BUN) or creatinine Intentional misuse
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Female, 15 year • Drug: MSK, Unknown • Reactions: Inappropriate defecation, Hyperthermia, Dehydration, Weight loss, Adipsia… • Outcome: Ongoing

  • Report ID: GBR-USFDACVM-2025-GB-000057
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 15.00 Year
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Inappropriate defecation Hyperthermia Dehydration Weight loss Adipsia Loss of appetite Polyuria Urine abnormalities NOS Elevated thyroxine Neutrophilia Anaemia NOS Nausea Stomatitis Lip disorder NOS Haemorrhagic diarrhoea Haematemesis
Outcomes: Ongoing

Dog, Weimaraner, Female, 16 month, 28.1 kilogram • Drug: MSK, Subcutaneous, Dose: 1 mL per animal, Frequency: 1 per day • Reactions: Injection site swelling, Hyperactivity, Abnormal cytology, Injection site skin change NOS, Local swelling… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-054707
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 16.00 Month
  • Weight: 28.100 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Dose: 1 mL per animal
  • Frequency: 1 per day
Reactions Reported:
Injection site swelling Hyperactivity Abnormal cytology Injection site skin change NOS Local swelling Injection site inflammation Injection site granuloma
Outcomes: Outcome Unknown

Dog, Shepherd Dog - German, Male, 10.5 year, 40.007 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Vocalisation, Abnormal tail posture, Pain NOS, Weight loss, Decreased appetite… • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2025-US-051900
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 10.50 Year
  • Weight: 40.007 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Vocalisation Abnormal tail posture Pain NOS Weight loss Decreased appetite Vomiting Chewing disorder Panting Trembling Lying down Anxiety Excessive chewing, licking and/or grooming Muscle atrophy Musculoskeletal disorder NOS Abnormal radiograph finding Spondylosis Joint effusion Elevated gamma-glutamyl transferase Lymphopenia Tiredness (lethargy) Thoracic pain Death by euthanasia Medication error NOS
Outcomes: Euthanized

Dog, Retriever - Labrador, Male, 4 year, 49 kilogram • Drug: MSK, Tablet, Oral, Dose: 2 tablet per dose, Frequency: 1 per day • Reactions: Decreased appetite, Drooling, Sleepiness - systemic disorder, Dull, Constipation • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-053693
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 4.00 Year
  • Weight: 49.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 2 tablet per dose
  • Frequency: 1 per day
Reactions Reported:
Decreased appetite Drooling Sleepiness - systemic disorder Dull Constipation
Outcomes: Outcome Unknown

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

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