Meds A-Z
Desoxycorticosterone Pivalate
Detailed information about Desoxycorticosterone Pivalate
Pet Owner Quick Guide
Start here: what this medicine is for, what it does, and when it's usually needed.
Usually used for:
For use as replacement therapy for the mineralocorticoid deficit in dogs with primary adrenocortical insufficiency.
What it does:
For use as replacement therapy for the mineralocorticoid deficit in dogs with primary adrenocortical insufficiency. For use as replacement therapy for mineralocorticoid deficiency in dogs with primary hypoadrenocorticism...
When it's needed:
For intramuscular use only. Do not use in pregnant dogs, dogs suffering from congestive heart disease, severe renal disease, or edema. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Call your vet sooner if you notice:
- For intramuscular use only. Do not use in pregnant dogs, dogs suffering from congestive heart disease, severe renal disease, or edema. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For subcutaneous use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Commonly reported reactions:
- (2 reports)
- (2 reports)
- (1 reports)
What to ask your vet today:
- Is this medicine the right fit for my pet’s current symptoms?
- Which warning signs mean I should call back right away?
- How should I handle missed doses or refusal to take the medicine?
Desoxycorticosterone Pivalate
Drug type: Generic ingredient • Branded profile • FDA branded products available
Species: Both
Manufacturer: MSK
Quick Facts
Official label facts first, then secondary summaries. Marketing content is separated below.
- https://animaldrugsatfda.fda.gov/adafda/views/#/home/previewsearch/141029 · official_label · FDA application profile
- https://animaldrugsatfda.fda.gov/adafda/views/#/home/previewsearch/141444 · official_label · FDA application profile
- https://animaldrugsatfda.fda.gov · fda_animal_drugs · Medication usage source
Warnings / Contraindications
For intramuscular use only. Do not use in pregnant dogs, dogs suffering from congestive heart disease, severe renal disease, or edema. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For subcutaneous use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
- High: For intramuscular use only. Do not use in pregnant dogs, dogs suffering from congestive heart disease, severe renal disease, or edema. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For subcutaneous use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
- https://animaldrugsatfda.fda.gov · fda_animal_drugs · Contraindication source
Adverse Reactions
Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.
Tap or hover a reaction to see what it means in plain language.
Most Reported Reactions
| Reaction | Cases | Species | Serious cases |
|---|---|---|---|
| 2 | Cat, Dog | 2 | |
| 2 | Cat, Dog | 1 | |
| 1 | Dog | 1 | |
| 1 | Cat | 1 | |
| 1 | Cat | 1 | |
| 1 | Dog | 1 | |
| 1 | Cat | 1 | |
| 1 | Cat | 1 |
Species coverage: Cat (21) Dog (11)
View detailed reaction table
| Reaction | Species | Seriousness | Frequency | Reports |
|---|---|---|---|---|
| Cat | Serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Dog | Non-serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Cat | Non-serious | - | 1 | |
| Dog | Non-serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Cat | Non-serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Dog | Non-serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Cat | Non-serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Cat | Non-serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Dog | Serious | - | 1 |
- https://api.fda.gov/animalandveterinary/event.json · adverse_reaction · openFDA case USA-USFDACVM-2021-US-000678
Storage & Handling
No storage/handling guidance is linked yet.
Documents
Official label facts are separated from secondary summaries.
Official documents: 4 • Secondary summaries: 0
- N141029 Org_1_12_1998.pdf · FOI
- Percorten™-V · SPL
- UCM488818.pdf · FOI
- Zycortal® Suspension · SPL
No source yet.
- https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/3622 · document · FOI
- https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1832/Percorten%E2%84%A2-V · document · SPL
- https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/936 · document · FOI
- https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/2339/Zycortal%C2%AE%20Suspension · document · SPL
Promotional Materials (Marketing)
This content is marketing material and not clinical guidance.
No marketing assets are linked yet.
No source yet.
Technical appendix (vet reference)
Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.
At a Glance
Quick facts and links to official labeling and safety signals.
- Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 10:44 PM UTC
-
Animal Drugs @ FDA:
Source FDA
| Refreshed Feb 16, 2026, 11:00 AM UTC
Applications/products are imported from FDA export data.
-
Animal Drugs @ FDA previews:
Source FDA
| Refreshed Feb 9, 2026, 3:05 AM UTC
Label highlights/doc links are fetched from FDA preview endpoints.
-
Animal Drug Product Listing Directory (NDC):
Source FDA
| Refreshed Feb 16, 2026, 11:00 AM UTC
Package/product NDCs from FDA’s electronic listing directory (XLS).
- openFDA reaction terms: Source FDA openFDA | Refreshed Feb 9, 2026, 3:13 AM UTC
- openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:21 AM UTC
Counseling and Monitoring Highlights
Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.
- For intramuscular use only. Do not use in pregnant dogs, dogs suffering from congestive heart disease, severe renal disease, or edema. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For subcutaneous use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian. (Contraindication, High)
Identifiers & Packages
Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.
| Package NDC | Product NDC | Form / Route | Status |
|---|---|---|---|
| 17033-382-04 | 17033 | - | |
| 58198-6450-0 | 58198 | - |
Enriched Documents
Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.
-
N141029 Org_1_12_1998.pdf
• FOI summary • Official
• June 18, 2018
FDA FOI summary for application 141029
-
UCM488818.pdf
• FOI summary • Official
• June 1, 2016
FDA FOI summary for application 141444
Data Sources & Revision History
Every non-trivial field is expected to include provenance and update timestamps.
- contraindications: For intramuscular use only. Do not use in pregnant dogs, dogs suffering from congestive heart disease, severe renal disease, or edema. Federal law restricts th… (Official, 2026-02-12)
- side_effects: Top reported reactions (openFDA): Immediate pain upon injection, High sodium-potassium ratio (Na:K ratio), Lethargy (see also Central nervous system depression… (Official, 2026-02-12)
- usage: For use as replacement therapy for the mineralocorticoid deficit in dogs with primary adrenocortical insufficiency. For use as replacement therapy for mineralo… (Official, 2026-02-12)
- side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
- contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
- usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
FDA Products & Applications (Animal Drugs @ FDA)
Official sponsor/proprietary-name/application-status records linked by active ingredient.
| Product | Sponsor | Application | Status | Published |
|---|---|---|---|---|
|
Percorten™-V
RX
Desoxycorticosterone Pivalate
Liquid (Suspension)
• Intramuscular
|
Elanco US Inc. | NADA 141-029 | Approved | Jun 18, 2018 |
|
Zycortal® Suspension
RX
Desoxycorticosterone Pivalate
Injectable Suspension
• Subcutaneous
|
Dechra, Ltd. | NADA 141-444 | Approved | Jun 1, 2016 |
Data source: FDA Animal Drugs @ FDA (public search export).
What It's For (FDA Label Highlights)
Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.
Composition / specifications
FDA page: Open in Animal Drugs @ FDA
Composition / specifications
FDA page: Open in Animal Drugs @ FDA
Official Documents (FDA)
Direct links to FDA-hosted PDFs and SPL packages (when available).
-
Summary
For use as replacement therapy for the mineralocorticoid deficit in dogs with primary adrenocortical insufficiency.
- Percorten™-V (ZIP)
FDA page: Open in Animal Drugs @ FDA
-
FOI UCM488818.pdf
Summary
For use as replacement therapy for mineralocorticoid deficiency in dogs with primary hypoadrenocorticism (Addison’s disease).
- Zycortal® Suspension (ZIP)
FDA page: Open in Animal Drugs @ FDA
Usage
For use as replacement therapy for the mineralocorticoid deficit in dogs with primary adrenocortical insufficiency. For use as replacement therapy for mineralocorticoid deficiency in dogs with primary hypoadrenocorticism (Addison’s disease).
Source: FDA Animal Drugs @ FDA • Reference
Contraindications
For intramuscular use only. Do not use in pregnant dogs, dogs suffering from congestive heart disease, severe renal disease, or edema. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For subcutaneous use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Side Effects
No approved side-effect narrative is linked yet.
openFDA reaction signals are available for Dog 8 and Cat 8 (view top reported reactions).
Top Reported Reactions (openFDA)
Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Adverse Event Case Summaries (openFDA)
These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.
Dog, Maltese, Female, 7 year, 6.486 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Shaking • Outcome: Recovered/Normal
- Report ID: USA-USFDACVM-2025-US-030815
- Serious AE: No
- Treated For AE: No
- Sex: Female
- Age: 7.00 Year
- Weight: 6.486 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Unassigned
Dog, ['Spitz - German Pomeranian', 'Poodle (unspecified)'], Female, 15 month, 4.5 kilogram • Drug: MSK, Unknown • Reactions: Fever, Hyperactivity, Vomiting, Itching • Outcome: Recovered/Normal
- Report ID: USA-USFDACVM-2025-US-025357
- Serious AE: No
- Treated For AE: No
- Sex: Female
- Age: 15.00 Month
- Weight: 4.500 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
Dog, Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog), Female, 7 year, 21.319 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Trauma NOS, Paraplegia, Hyposensitivity to pain, Unable to walk, Drunken gait… • Outcome: Ongoing
- Report ID: USA-USFDACVM-2025-US-019689
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Female
- Age: 7.00 Year
- Weight: 21.319 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Unassigned
Dog, ['Shepherd Dog - German', 'Dog (unknown)'], Female, 10 year, 31.75 kilogram • Drug: MSK, Unknown • Reactions: Coprophagia, Lack of efficacy (endoparasite) - whipworm, Addison's disease • Outcome: Ongoing
- Report ID: USA-USFDACVM-2025-US-010338
- Serious AE: Yes
- Treated For AE: No
- Sex: Female
- Age: 10.00 Year
- Weight: 31.750 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
Dog, Crossbred Canine/dog, Female, 4 year, 27.7 kilogram • Drug: MSK, Unknown, Dose: 2.30 mL per animal • Reactions: High sodium-potassium ratio, Hypochloraemia, Weight gain, Vulvar oedema, Polyphagia… • Outcome: Ongoing
- Report ID: USA-USFDACVM-2025-US-010109
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Female
- Age: 4.00 Year
- Weight: 27.700 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Dose: 2.30 mL per animal
Cat, Domestic Shorthair, Male, 5 year, 5.41 kilogram • Drug: MSK, Injection, suspension, Subcutaneous, Dose: 1.85 Milligram per kilogram • Reactions: Vomiting, Gastrointestinal foreign body NOS, Abnormal ultrasound finding, Loss of appetite, Hyperglycaemia… • Outcome: Ongoing
- Report ID: USA-USFDACVM-2021-US-000678
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Male
- Age: 5.00 Year
- Weight: 5.410 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Subcutaneous
- Form: Injection, suspension
- Dose: 1.85 Milligram per kilogram
Cat, Birman (Sacred Birman), Female, 8 year • Drug: MSK, Injection, suspension, Unknown • Reactions: Loss of appetite, Lack of efficacy - NOS • Outcome: Recovered/Normal
- Report ID: USA-USFDACVM-2019-US-052741
- Serious AE: No
- Treated For AE: No
- Sex: Female
- Age: 8.00 Year
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Injection, suspension
Cat, Domestic Shorthair, Male, 14 year, 6.23 kilogram • Drug: MSK, Injection, suspension, Intramuscular, Dose: 4.01 Milligram per kilogram • Reactions: Hypoglycaemia, High sodium-potassium ratio, Medication error • Outcome: Outcome Unknown
- Report ID: USA-USFDACVM-2019-US-024335
- Serious AE: No
- Treated For AE: No
- Sex: Male
- Age: 14.00 Year
- Weight: 6.230 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Intramuscular
- Form: Injection, suspension
- Dose: 4.01 Milligram per kilogram
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Overdose Information
No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.
Storage & Handling
No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.
Share Your Thoughts
Let others know your experience or advice regarding this medication.
This medication has not been reviewed by a veterinarian yet.