Meds A-Z
Porcine Insulin
Detailed information about Porcine Insulin
Pet Owner Quick Guide
Start here: what this medicine is for, what it does, and when it's usually needed.
Usually used for:
For the reduction of hyperglycemia and hyperglycemia-associated clinical signs in dogs with diabetes mellitus.
What it does:
For the reduction of hyperglycemia and hyperglycemia-associated clinical signs in dogs with diabetes mellitus. For the reduction of hyperglycemia and hyperglycemia-associated clinical signs in cats with diabetes mellitus...
When it's needed:
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Call your vet sooner if you notice:
- Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Commonly reported reactions:
- (1 reports)
- (1 reports)
- (1 reports)
What to ask your vet today:
- Is this medicine the right fit for my pet’s current symptoms?
- Which warning signs mean I should call back right away?
- How should I handle missed doses or refusal to take the medicine?
Porcine Insulin
Drug type: Generic ingredient • Branded profile • FDA branded products available
Species: Both
Manufacturer: MSK
Quick Facts
Official label facts first, then secondary summaries. Marketing content is separated below.
- https://animaldrugsatfda.fda.gov/adafda/views/#/home/previewsearch/141236 · official_label · FDA application profile
- https://animaldrugsatfda.fda.gov · fda_animal_drugs · Medication usage source
Warnings / Contraindications
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
- High: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
- https://animaldrugsatfda.fda.gov · fda_animal_drugs · Contraindication source
Adverse Reactions
Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.
Tap or hover a reaction to see what it means in plain language.
Most Reported Reactions
| Reaction | Cases | Species | Serious cases |
|---|---|---|---|
| 1 | Dog | 1 | |
| 1 | Dog | 1 | |
| 1 | Dog | 1 | |
| 1 | Dog | 1 | |
| 1 | Cat | 1 | |
| 1 | Dog | 1 | |
| 1 | Cat | 1 | |
| 1 | Cat | 1 |
Species coverage: Dog (22) Cat (10)
View detailed reaction table
| Reaction | Species | Seriousness | Frequency | Reports |
|---|---|---|---|---|
| Cat | Serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Dog | Non-serious | - | 1 | |
| Dog | Non-serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Dog | Non-serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Dog | Non-serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Dog | Non-serious | - | 1 | |
| Cat | Serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Dog | Non-serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Dog | Non-serious | - | 1 | |
| Dog | Serious | - | 1 | |
| Cat | Unknown | - | - | |
| Dog | Unknown | - | - | |
| Cat | Unknown | - | - | |
| Dog | Unknown | - | - |
- https://api.fda.gov/animalandveterinary/event.json · adverse_reaction · openFDA case USA-USFDACVM-2023-US-008410
Storage & Handling
No storage/handling guidance is linked yet.
Documents
Official label facts are separated from secondary summaries.
Official documents: 7 • Secondary summaries: 0
- UCM391560.pdf · FOI
- UCM374300.pdf · FOI
- ucm118049.pdf · FOI
- ucm118048.pdf · FOI
- CIS VETSULIN N141236C0179-2.pdf · Labeling
- PI VETSULIN N141236C0179.pdf · Labeling
- Vetsulin® · SPL
No source yet.
- https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/781 · document · FOI
- https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/780 · document · FOI
- https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/779 · document · FOI
- https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/778 · document · FOI
- https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadLabeling/915 · document · Labeling
- https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadLabeling/916 · document · Labeling
- https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/283/Vetsulin%C2%AE · document · SPL
Promotional Materials (Marketing)
This content is marketing material and not clinical guidance.
No marketing assets are linked yet.
No source yet.
Technical appendix (vet reference)
Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.
At a Glance
Quick facts and links to official labeling and safety signals.
- Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 10:44 PM UTC
-
Animal Drugs @ FDA:
Source FDA
| Refreshed Feb 16, 2026, 11:00 AM UTC
Applications/products are imported from FDA export data.
-
Animal Drugs @ FDA previews:
Source FDA
| Refreshed Feb 9, 2026, 3:05 AM UTC
Label highlights/doc links are fetched from FDA preview endpoints.
-
Animal Drug Product Listing Directory (NDC):
Source FDA
| Refreshed Feb 16, 2026, 11:00 AM UTC
Package/product NDCs from FDA’s electronic listing directory (XLS).
- openFDA reaction terms: Source FDA openFDA | Refreshed Feb 16, 2026, 11:03 AM UTC
- openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:21 AM UTC
Counseling and Monitoring Highlights
Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.
- Federal law restricts this drug to use by or on the order of a licensed veterinarian. (Contraindication, High)
Identifiers & Packages
Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.
Enriched Documents
Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.
-
PI VETSULIN N141236C0179.pdf
• Official label • Official
• July 1, 2024
FDA official labeling for application 141236
-
CIS VETSULIN N141236C0179-2.pdf
• Official label • Official
• July 1, 2024
FDA official labeling for application 141236
-
ucm118048.pdf
• FOI summary • Official
• July 1, 2024
FDA FOI summary for application 141236
-
ucm118049.pdf
• FOI summary • Official
• July 1, 2024
FDA FOI summary for application 141236
-
UCM374300.pdf
• FOI summary • Official
• July 1, 2024
FDA FOI summary for application 141236
-
UCM391560.pdf
• FOI summary • Official
• July 1, 2024
FDA FOI summary for application 141236
Data Sources & Revision History
Every non-trivial field is expected to include provenance and update timestamps.
- contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. (Official, 2026-02-12)
- side_effects: Top reported reactions (openFDA): Hind limb paresis, Hyperglycaemia, Uncontrolled diabetes, Underdose, Blindness, Cloudy eye (for Miosis, Mydriasis, Anisocoria… (Official, 2026-02-12)
- usage: For the reduction of hyperglycemia and hyperglycemia-associated clinical signs in dogs with diabetes mellitus. For the reduction of hyperglycemia and hyperglyc… (Official, 2026-02-12)
- side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
- contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
- usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
FDA Products & Applications (Animal Drugs @ FDA)
Official sponsor/proprietary-name/application-status records linked by active ingredient.
| Product | Sponsor | Application | Status | Published |
|---|---|---|---|---|
|
Vetsulin®
RX
Porcine insulin zinc suspension
Liquid (Suspension)
• Subcutaneous
|
Intervet, Inc. | NADA 141-236 | Approved | Jul 1, 2024 |
Data source: FDA Animal Drugs @ FDA (public search export).
What It's For (FDA Label Highlights)
Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.
Composition / specifications
For the reduction of hyperglycemia and hyperglycemia-associated clinical signs in cats with diabetes mellitus.
Administer an initial dose of 1 to 2 IU by subcutaneous injection. Injections should be given twice daily at approximately 12-hour intervals. For cats fed twice daily, the injections should be concurrent with or right after a meal. For cats fed ad libitum, no change in feeding is needed. Adjust the dose at appropriate intervals based on clinical signs, urinalysis results, and glucose curve values until adequate glycemic control has been attained.
FDA page: Open in Animal Drugs @ FDA
Official Documents (FDA)
Direct links to FDA-hosted PDFs and SPL packages (when available).
-
FOI UCM391560.pdf
Summary
The effect of the supplementis to add a 2.7 mL cartridge presentation for use with the VETPEN automatic injection device. -
FOI UCM374300.pdf
Summary
The effect of the supplement is to change the specification for non-extractable (NE) insulin. -
FOI ucm118049.pdf
Summary
This supplement provides for a new starting dose in dogs and for the use of VETSULIN in cats. -
FOI ucm118048.pdf
Summary
For the reduction of hyperglycemia and hyperglycemia associated clinical signs with diabetes mellitus. -
Labeling CIS VETSULIN N141236C0179-2.pdf
-
Labeling PI VETSULIN N141236C0179.pdf
- Vetsulin® (ZIP)
FDA page: Open in Animal Drugs @ FDA
Usage
For the reduction of hyperglycemia and hyperglycemia-associated clinical signs in dogs with diabetes mellitus. For the reduction of hyperglycemia and hyperglycemia-associated clinical signs in cats with diabetes mellitus.
Source: FDA Animal Drugs @ FDA • Reference
Contraindications
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Side Effects
No approved side-effect narrative is linked yet.
openFDA reaction signals are available for Dog 38 and Cat 8 (view top reported reactions).
Top Reported Reactions (openFDA)
Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Adverse Event Case Summaries (openFDA)
These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.
Dog, Spitz - German Pomeranian, Male, 11 year, 4.72 kilogram • Drug: MSK, Injection, solution, Subcutaneous, Dose: 4 Other per animal, Frequency: 12 per hour • Reactions: Stroke, Facial paralysis, Cloudy eye, Elevated triglyceride, Elevated cholesterol • Outcome: Ongoing
- Report ID: USA-USFDACVM-2025-US-050105
- Serious AE: Yes
- Treated For AE: No
- Sex: Male
- Age: 11.00 Year
- Weight: 4.720 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Subcutaneous
- Form: Injection, solution
- Dose: 4 Other per animal
- Frequency: 12 per hour
Cat, Domestic Shorthair, Male, 14 year, 5.216 kilogram • Drug: MSK, Injection, suspension, Subcutaneous • Reactions: General illness, Blood in vomit, Not eating, Regenerative anaemia, Non-regenerative anaemia… • Outcome: Ongoing
- Report ID: USA-USFDACVM-2023-US-008410
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Male
- Age: 14.00 Year
- Weight: 5.216 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Subcutaneous
- Form: Injection, suspension
Dog, ['Spitz - Japanese', 'Dog (unknown)'], Female, 12 year, 16.7 kilogram • Drug: MSK, Subcutaneous • Reactions: Hyperglycaemia, Underdose, No sign • Outcome: Outcome Unknown
- Report ID: USA-USFDACVM-2020-US-062023
- Serious AE: No
- Treated For AE: No
- Sex: Female
- Age: 12.00 Year
- Weight: 16.700 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Subcutaneous
Dog, Crossbred Canine/dog, Male, 14 year, 27.216 kilogram • Drug: MSK, Subcutaneous • Reactions: Muscle weakness NOS, Recumbency, Hind limb paresis, Unable to stand • Outcome: Recovered/Normal
- Report ID: USA-USFDACVM-2020-US-061377
- Serious AE: No
- Treated For AE: No
- Sex: Male
- Age: 14.00 Year
- Weight: 27.216 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Subcutaneous
Dog, ['Schnauzer - Miniature', 'Poodle - Miniature'], Female, 13.5 year, 6.622 kilogram • Drug: MSK, Subcutaneous • Reactions: Uncontrolled diabetes, Hyperglycaemia • Outcome: Outcome Unknown
- Report ID: USA-USFDACVM-2020-US-061362
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Female
- Age: 13.50 Year
- Weight: 6.622 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Subcutaneous
Dog, Chihuahua, Female, 10 year, 5.761 kilogram • Drug: MSK, Unknown • Reactions: Uncontrolled diabetes, Blindness, Thromboemboli, Corneal ulcer, Death by euthanasia… • Outcome: Euthanized
- Report ID: USA-USFDACVM-2018-US-030461
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Female
- Age: 10.00 Year
- Weight: 5.761 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Overdose Information
No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.
Storage & Handling
No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.
Share Your Thoughts
Let others know your experience or advice regarding this medication.
This medication has not been reviewed by a veterinarian yet.