Skip to main content

Need urgent help? Start triage first, then route to emergency care.

Meds A-Z

Phenylpropanolamine Hcl

Detailed information about Phenylpropanolamine Hcl

Official label facts Owner quick guide first Marketing clearly labeled
Showing simplified owner view. Switch to Vet View for full technical detail.

Pet Owner Quick Guide

Start here: what this medicine is for, what it does, and when it's usually needed.

Usually used for:

Use this medication only when your veterinarian confirms it matches your pet's condition.

What it does:

Use this medication only when your veterinarian confirms it matches your pet's condition.

When it's needed:

Use this medication only when your veterinarian confirms it matches your pet's condition.

Commonly reported reactions:

  • (1 reports)
  • (1 reports)
  • (1 reports)

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Talk to a Vet / Find a Vet Near You
Image coming soon
Phenylpropanolamine Hcl

Phenylpropanolamine Hcl

Drug type: Generic ingredient • Generic profile No FDA branded products linked

Species: Both

Manufacturer: MSK

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: MSK
Form: No source yet
Identifiers:

No source yet.

Source metadata: No source yet.

Warnings / Contraindications

No contraindication summary is linked yet.

No owner-focused warning rows are linked yet.

Source metadata: No source yet.

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
28
Reported cases
17
Serious reports
4
Species represented
2
Most Reported Reactions
Reaction Cases Species Serious cases
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 0
1 Dog 0
1 Dog 0
1 Dog 0

Species coverage: Dog (22) Cat (6)

View detailed reaction table
Reaction Species Seriousness Frequency Reports
Cat Non-serious - 1
Cat Non-serious - 1
Dog Non-serious - 1
Dog Serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Cat Non-serious - 1
Dog Non-serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Serious - 1
Dog Unknown - -
Cat Unknown - -
Dog Unknown - -
Dog Unknown - -
Cat Unknown - -
Dog Unknown - -
Cat Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Source metadata:

Storage & Handling

No storage/handling guidance is linked yet.

Source metadata: No source yet.

Documents

Official label facts are separated from secondary summaries.

No linked label PDFs or safety notices yet.

Official label facts

No source yet.

Secondary summaries

No source yet.

Source metadata: No source yet.

Promotional Materials (Marketing)

This content is marketing material and not clinical guidance.

No marketing assets are linked yet.

No source yet.

Source metadata: No source yet.
Talk to a Vet / Find a Vet Near You
Technical appendix (vet reference)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 9, 2026, 3:14 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:21 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 8 Cat 3 View
Case summaries: 7 (showing 7) View
openFDA reports are unverified and do not prove causation.

Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Accidental exposure (1) Emesis (1) Eye disorder NOS (for photophobia see 'neurological') (1) Gastric ulcer (1) Inappropriate defecation (1) Keratoconjunctivitis (1) Lack of efficacy (bacteria) - Ehrlichia (1) Lack of efficacy (ectoparasite) - tick NOS (1) Lack of efficacy (endoparasite) - hookworm (1) Lack of efficacy - NOS (1) Overdose (1) Peritonitis (1) Regurgitation (1) Shaking (1) Strabismus (1) Uncomfortable (1)

Data Sources & Revision History

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Overdose, Underdose, Emesis, Lethargy (see also Central nervous system depression in 'Neurological'), Accidental exposure, Pa… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

No linked FDA product applications are available for this ingredient yet.

Usage

No approved usage text is linked yet for this ingredient.

  • Catalog species: Both
  • Safety reports available: 7 openFDA case summaries (view)

Contraindications

No approved contraindication text is linked yet. Review FDA label highlights and openFDA safety reports before making treatment decisions.

Side Effects

No approved side-effect narrative is linked yet.

openFDA reaction signals are available for Dog 8 and Cat 3 (view top reported reactions).

Top Reported Reactions (openFDA)

Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).

Dog
Digestive
Vomiting (119)
Neurologic
Tiredness (lethargy) (117)
Other
Overdose (192) Underdose (149) Accidental exposure (107) Panting (97) Agitation (69) Erythema (64)
Cat
Digestive
Vomiting (1)
Effectiveness
Lack of efficacy - NOS (1)
Other
Accidental exposure (1)

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Retriever - Labrador, Female, 7 year, 28.18 kilogram • Drug: MSK, Oral • Reactions: Vomiting, Regurgitation, Gastric ulcer, Peritonitis • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2023-US-039145
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 7.00 Year
  • Weight: 28.180 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
Reactions Reported:
Vomiting Regurgitation Gastric ulcer Peritonitis
Outcomes: Outcome Unknown

Dog, ['Retriever - Labrador', 'Dog (unknown)'], Female, 14 year, 17.7 kilogram • Drug: MSK, Oral • Reactions: Lack of efficacy (ectoparasite) - tick NOS, Lack of efficacy (bacteria) - Ehrlichia • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2023-US-023225
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 14.00 Year
  • Weight: 17.700 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
Reactions Reported:
Lack of efficacy (ectoparasite) - tick NOS Lack of efficacy (bacteria) - Ehrlichia
Outcomes: Outcome Unknown

Dog, Bulldog - American, Male, 8.5 year, 23.9 kilogram • Drug: MSK, Unknown, Dose: 1 dose per animal, Frequency: 1 per day • Reactions: Lack of efficacy (endoparasite) - hookworm • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2023-US-021616
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 8.50 Year
  • Weight: 23.900 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Dose: 1 dose per animal
  • Frequency: 1 per day
Reactions Reported:
Lack of efficacy (endoparasite) - hookworm
Outcomes: Outcome Unknown

Dog, ['Retriever - Labrador', 'Poodle (unspecified)'], Female, 10 year, 24 kilogram • Drug: MSK, Unknown • Reactions: Shaking, Overdose • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2023-US-017281
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 10.00 Year
  • Weight: 24.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Shaking Overdose
Outcomes: Recovered/Normal

Dog, Chihuahua, Male, 13 year, 3.5 kilogram • Drug: MSK, Unknown • Reactions: Eye disorder NOS, Uncomfortable, Inappropriate defecation, Keratoconjunctivitis, Strabismus • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2023-US-001662
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 13.00 Year
  • Weight: 3.500 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Eye disorder NOS Uncomfortable Inappropriate defecation Keratoconjunctivitis Strabismus
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 11 year, 5.44 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 6.25 Milligram per animal, Frequency: 12 per hour • Reactions: Lack of efficacy - NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2016-US-051398
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 11.00 Year
  • Weight: 5.440 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 6.25 Milligram per animal
  • Frequency: 12 per hour
Reactions Reported:
Lack of efficacy - NOS
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Male, 2 year, 2.72 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 50 Milligram per animal, Frequency: 1 per day • Reactions: Vomiting, Accidental exposure • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2016-US-008444
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 2.00 Year
  • Weight: 2.720 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 50 Milligram per animal
  • Frequency: 1 per day
Reactions Reported:
Vomiting Accidental exposure
Outcomes: Recovered/Normal

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

Share Your Thoughts

Let others know your experience or advice regarding this medication.

This medication has not been reviewed by a veterinarian yet.