Skip to main content

Need urgent help? Start triage first, then route to emergency care.

Start symptom intake Emergency vets near you

Meds A-Z

Midazolam

Detailed information about Midazolam

Official label facts Owner quick guide first Marketing clearly labeled
Talk to a Vet / Find a Vet Near You Start Symptom Intake
Showing simplified owner view. Switch to Vet View for full technical detail.

Pet Owner Quick Guide

Start here: what this medicine is for, what it does, and when it's usually needed.

Usually used for:

Use this medication only when your veterinarian confirms it matches your pet's condition.

What it does:

Use this medication only when your veterinarian confirms it matches your pet's condition.

When it's needed:

Use this medication only when your veterinarian confirms it matches your pet's condition.

Commonly reported reactions:

  • (2 reports)
  • (2 reports)
  • (2 reports)

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Talk to a Vet / Find a Vet Near You
Image coming soon
Midazolam

Midazolam

Drug type: Generic ingredient • Generic profile • No FDA branded products linked

Species: Both

Manufacturer: MSK

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: MSK
Form: No source yet
Identifiers:

No source yet.

Source metadata: No source yet.

Warnings / Contraindications

No contraindication summary is linked yet.

No owner-focused warning rows are linked yet.

Source metadata: No source yet.

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
30
Species represented
2
Most Reported Reactions
Reaction Cases Species Serious cases
2 Cat, Dog 2
2 Cat, Dog 1
2 Cat, Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Cat 1

Species coverage: Cat (18) Dog (14)

View detailed reaction table
Reaction Species Seriousness Frequency Reports
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Non-serious - 1
Cat Non-serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Source metadata:

Storage & Handling

No storage/handling guidance is linked yet.

Source metadata: No source yet.

Documents

Official label facts are separated from secondary summaries.

No linked label PDFs or safety notices yet.

Official label facts

No source yet.

Secondary summaries

No source yet.

Source metadata: No source yet.

Promotional Materials (Marketing)

This content is marketing material and not clinical guidance.

No marketing assets are linked yet.

No source yet.

Source metadata: No source yet.
Talk to a Vet / Find a Vet Near You
Technical appendix (vet reference)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 16, 2026, 11:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 12, 2026, 10:43 PM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 56 • Cat 56 • View
Case summaries: 11 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Abnormal cytology (1) Adipsia (1) Anaemia NOS (1) Anorexia (1) Anorexia (1) Ataxia (1) Constipation (1) Death (1) Dehydration (1) Dysphoria (1) Dyspnoea (1) Elevated thyroxine (T4) (1) Emesis (multiple) (1) Excessive chewing, licking and/or grooming (1) Faecal incontinence (1) Falling (1)

Data Sources & Revision History

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Vomiting, Seizure NOS, Death, Lethargy (see also Central nervous system depression in Neurological), Diarrhoea, Death by euth… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

No linked FDA product applications are available for this ingredient yet.

Usage

No approved usage text is linked yet for this ingredient.

  • Catalog species: Both
  • Safety reports available: 11 openFDA case summaries (view)

Contraindications

No approved contraindication text is linked yet. Review FDA label highlights and openFDA safety reports before making treatment decisions.

Side Effects

No approved side-effect narrative is linked yet.

openFDA reaction signals are available for Dog 56 and Cat 56 (view top reported reactions).

Top Reported Reactions (openFDA)

Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).

Dog
Digestive
Vomiting (93) Diarrhea (54) Loss of appetite (2) Loss of appetite (2) Loss of appetite (2) Loss of appetite (2) Loss of appetite (2) Loss of appetite (2)
Neurologic
Seizure NOS (87) Tiredness (lethargy) (61) Tiredness (lethargy) (4) Tiredness (lethargy) (4) Tiredness (lethargy) (4) Tiredness (lethargy) (4) Seizure NOS (3) Seizure NOS (3) Seizure NOS (3) Seizure NOS (3) Seizure NOS (3) Tiredness (lethargy) (3) Tiredness (lethargy) (3)
Behavior
Anxiety (2) Anxiety (2) Anxiety (2) Anxiety (2) Anxiety (2) Anxiety (2)
Other
Death (79) Death by euthanasia (52) Not eating (48) Tachycardia (45) Fever (3) Fever (3) Fever (3) Fever (3) Not eating (3) Not eating (3) Not eating (3) Not eating (3) Not eating (3) Not eating (3) Trouble breathing (dyspnea) (3) Trouble breathing (dyspnea) (3) Trouble breathing (dyspnea) (3) Trouble breathing (dyspnea) (3) Trouble breathing (dyspnea) (3) Trouble breathing (dyspnea) (3) Abnormal cytology (2) Abnormal cytology (2) Abnormal cytology (2) Abnormal cytology (2) Abnormal cytology (2) Abnormal cytology (2) Cough (2) Cough (2) Elevated total bilirubin (2)
Cat
Digestive
Loss of appetite (39)
Neurologic
Tiredness (lethargy) (37) Unsteady walking (ataxia) (36) Unsteady walking (ataxia) (2) Unsteady walking (ataxia) (2) Unsteady walking (ataxia) (2) Unsteady walking (ataxia) (2) Unsteady walking (ataxia) (2) Unsteady walking (ataxia) (2)
Behavior
Behavioral disorder (unspecified) (65)
Other
Not eating (62) Dilated pupils (54) Dysphoria (54) Hyperactivity (52) Dysphoria (3) Dysphoria (3) Dysphoria (3) Dysphoria (3) Dysphoria (3) Dysphoria (3) Recovery prolonged (3) Recovery prolonged (3) Recovery prolonged (3) Recovery prolonged (3) Recovery prolonged (3) Recovery prolonged (3) Not eating (2) Not eating (2) Not eating (2) Not eating (2) Not eating (2) Not eating (2) Not himself/herself (2) Not himself/herself (2) Not himself/herself (2) Not himself/herself (2) Not himself/herself (2) Not himself/herself (2) Adipsia (1) Adipsia (1) Adipsia (1) Adipsia (1) Adipsia (1) Adipsia (1) Agitation (1) Agitation (1) Agitation (1) Agitation (1) Agitation (1) Agitation (1) Anaemia NOS (1) Anaemia NOS (1) Anaemia NOS (1) Anaemia NOS (1) Anaemia NOS (1) Anaemia NOS (1)

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Cat, Cat (other), Male, 13 year, 3.49 kilogram • Drug: MSK, Unknown • Reactions: Slow heart rate, Recovery prolonged • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-055510
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 13.00 Year
  • Weight: 3.490 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Slow heart rate Recovery prolonged
Outcomes: Recovered/Normal

Cat, Maine Coon, Female, 11 year, 4.58 kilogram • Drug: MSK, Unknown • Reactions: Recovery prolonged • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-055867
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 11.00 Year
  • Weight: 4.580 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Recovery prolonged
Outcomes: Recovered/Normal

Dog, Crossbred Canine/dog, Male, 10 year, 33.112 kilogram • Drug: MSK, Injection, solution, Intramuscular, Dose: 3 Milligram per animal • Reactions: Urinary incontinence, Faecal incontinence, Tiredness (lethargy), Tremors, Loss of appetite… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-054275
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 10.00 Year
  • Weight: 33.112 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intramuscular
  • Form: Injection, solution
  • Dose: 3 Milligram per animal
Reactions Reported:
Urinary incontinence Faecal incontinence Tiredness (lethargy) Tremors Loss of appetite Sedation prolonged Leucopenia NOS Lymphopenia Lack of efficacy - NOS Unable to walk Pyuria Haematuria Urinary tract infection
Outcomes: Ongoing

Dog, Crossbred Canine/dog, Female, 13.83 year, 16.329 kilogram • Drug: MSK, Injection, solution, Unknown • Reactions: Falling, Shaking, Drooling, Panting, Vomiting… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-053347
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 13.83 Year
  • Weight: 16.329 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Injection, solution
Reactions Reported:
Falling Shaking Drooling Panting Vomiting Not eating Nystagmus Tachycardia
Outcomes: Ongoing

Cat, Domestic Shorthair, Female, 15 year • Drug: MSK, Unknown • Reactions: Inappropriate defecation, Hyperthermia, Dehydration, Weight loss, Adipsia… • Outcome: Ongoing

  • Report ID: GBR-USFDACVM-2025-GB-000057
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 15.00 Year
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Inappropriate defecation Hyperthermia Dehydration Weight loss Adipsia Loss of appetite Polyuria Urine abnormalities NOS Elevated thyroxine Neutrophilia Anaemia NOS Nausea Stomatitis Lip disorder NOS Haemorrhagic diarrhoea Haematemesis
Outcomes: Ongoing

Dog, Dog (unknown), Unknown • Drug: MSK, Unknown • Reactions: Regurgitation • Outcome: Outcome Unknown

  • Report ID: GBR-USFDACVM-2025-GB-000058
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Unknown
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Regurgitation
Outcomes: Outcome Unknown

Dog, Weimaraner, Female, 16 month, 28.1 kilogram • Drug: MSK, Subcutaneous, Dose: 1.13 mL per animal, Frequency: 1 per day • Reactions: Injection site swelling, Hyperactivity, Abnormal cytology, Injection site skin change NOS, Local swelling… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-054707
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 16.00 Month
  • Weight: 28.100 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Dose: 1.13 mL per animal
  • Frequency: 1 per day
Reactions Reported:
Injection site swelling Hyperactivity Abnormal cytology Injection site skin change NOS Local swelling Injection site inflammation Injection site granuloma
Outcomes: Outcome Unknown

Dog, Dog (unknown), Unknown • Drug: MSK, Unknown • Reactions: Regurgitation, Death, Trouble breathing (dyspnea) • Outcome: Died

  • Report ID: GBR-USFDACVM-2025-GB-000059
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Unknown
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Regurgitation Death Trouble breathing (dyspnea)
Outcomes: Died

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

Share Your Thoughts

Let others know your experience or advice regarding this medication.

This medication has not been reviewed by a veterinarian yet.