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Meds A-Z

Carprofen

Detailed information about Carprofen

Official label facts Owner quick guide first Marketing clearly labeled
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Pet Owner Quick Guide

Start here: what this medicine is for, what it does, and when it's usually needed.

Usually used for:

For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries

What it does:

NSAID used for pain and inflammation (commonly osteoarthritis and post-operative pain in dogs).

When it's needed:

Avoid combining with other NSAIDs or corticosteroids. Use caution with kidney/liver disease or GI ulcer history.

Call your vet sooner if you notice:

  • Avoid combining with other NSAIDs or corticosteroids. Use caution with kidney/liver disease or GI ulcer history.

Commonly reported reactions:

  • (2 reports)
  • (1 reports)
  • (1 reports)

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
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Image for Carprofen

Carprofen

Drug type: Generic ingredient • Branded profile FDA branded products available

Species: Dog

Manufacturer: Elanco

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Dog
Manufacturer: Elanco
Form: Caplet, Chewable Tablets, Flavored Tablets, Injectable Solution, Liquid (Solution), Scored Chewable Tablets
Identifiers:
ANADA: 200366 ANADA: 200397 ANADA: 200490 ANADA: 200498 ANADA: 200520 ANADA: 200522 ANADA: 200555 ANADA: 200575 ANADA: 200578 ANADA: 200593 ANADA: 200595 ANADA: 200681 ANADA: 200687 ANADA: 200703 ANADA: 200706 ANADA: 200732 ANADA: 200739 ANADA: 200762 ANADA: 200767 ANADA: 200777
Source metadata:

Warnings / Contraindications

Avoid combining with other NSAIDs or corticosteroids. Use caution with kidney/liver disease or GI ulcer history.

  • High: Avoid combining with other NSAIDs or corticosteroids. Use caution with kidney/liver disease or GI ulcer history.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
29
Serious reports
25
Species represented
2
Most Reported Reactions
Reaction Cases Species Serious cases
2 Cat, Dog 2
1 Cat 1
1 Dog 1
1 Dog 1
1 Cat 1
1 Dog 1
1 Dog 1
1 Dog 1

Species coverage: Cat (16) Dog (16)

View detailed reaction table
Reaction Species Seriousness Frequency Reports
Cat Non-serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Non-serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Non-serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Non-serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Source metadata:

Storage & Handling

Store at room temperature in a dry place.

Source metadata: No source yet.

Documents

Official label facts are separated from secondary summaries.

Official documents: 80 • Secondary summaries: 0

Official label facts
Secondary summaries

No source yet.

Promotional Materials (Marketing)

This content is marketing material and not clinical guidance.

No marketing assets are linked yet.

No source yet.

Source metadata: No source yet.
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Technical appendix (vet reference)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 7:40 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 16, 2026, 11:01 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:19 AM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: CARPRIEVE® CARPROFEN Chewable Tablets CARPROFEN Soft Chewable Tablets Carofenvet™ Carprieve® Chewable Tablets Carprieve® Injection Carprofen Carprofen Chewable Tablets Carprofen Flavored Tablets Carprofen Injection Carprofen Sterile Injectable Solution Carprofen Tablets Novox® Caplets Carprofen Caplets Rimadyl® Caplets Rimadyl® Chewable Tablets Rimadyl® Sterile Injectable Solution Vetprofen™ quellin®
Case-reported brands (openFDA): MSK
Catalog species: Dog FDA-labeled species: Dog
Rx/OTC: RX
Form/route: Caplet, Chewable Tablets, Flavored Tablets, Injectable Solution, Liquid (Solution), Scored Chewable Tablets, Soft Chewable Tablet, Tablet, Tablet (Chewable) Oral, Subcutaneous
Applications: ANADA 200-575 • ANADA 200-366 • ANADA 200-767 • ANADA 200-578 • ANADA 200-397 • ANADA 200-762 • ANADA 200-687 • ANADA 200-777 • ANADA 200-706 • ANADA 200-795 • ANADA 200-739 • ANADA 200-498 • ANADA 200-732 • ANADA 200-520 • NADA 141-199 • ANADA 200-703 • ANADA 200-681 • ANADA 200-490 • NADA 141-053 • NADA 141-111 • ANADA 200-522 • ANADA 200-595 • ANADA 200-593 • ANADA 200-555
NDC: Packages 11695-6935-1 11695-6935-2 11695-7004-0 11695-7004-1 11695-7004-2 11695-7005-0 Products 11695 11695 11695 11695 11695 11695
Documents: 55 (FOI: 30) • SPL: 25 Label highlights Official documents
Safety (openFDA)
Top reactions: Dog 56 Cat 42 View
Case summaries: 10 (showing 8) View
openFDA reports are unverified and do not prove causation.

Explore
Linked using: Fda_Label (0.95), Fda_Label (0.95), Fda_Label (0.95)

Diagnosis Codes
ICD10_CM: M19.90
Unspecified osteoarthritis, unspecified site

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Avoid combining with other NSAIDs or corticosteroids. Use caution with kidney/liver disease or GI ulcer history. (Contraindication, High)
Top reaction signals
Accidental exposure (1) Bloody diarrhoea (1) Death by euthanasia (1) Dilated pupils (1) Elevated alanine aminotransferase (ALT) (1) Elevated alanine aminotransferase (ALT) (1) Elevated aspartate aminotransferase (AST) (1) Elevated gamma-glutamyl transferase (GGT) (1) Emesis (1) Enamel disorder (1) Eosinophilia (1) Fever (1) General illness (1) Haematemesis (1) Hiding (1) Hind limb paresis (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
ANADA: 200366 ANADA: 200397 ANADA: 200490 ANADA: 200498 ANADA: 200520 ANADA: 200522 ANADA: 200555 ANADA: 200575 ANADA: 200578 ANADA: 200593 ANADA: 200595 ANADA: 200681 ANADA: 200687 ANADA: 200703 ANADA: 200706 ANADA: 200732 ANADA: 200739 ANADA: 200762 ANADA: 200767 ANADA: 200777 ANADA: 200795 NADA: 141053 NADA: 141111 NADA: 141199
Package NDC Product NDC Form / Route Status
11695-6935-1 11695 -
11695-6935-2 11695 -
11695-7001-1 11695 -
11695-7001-2 11695 -
11695-7001-3 11695 -
11695-7002-1 11695 -
11695-7002-2 11695 -
11695-7002-3 11695 -
11695-7003-1 11695 -
11695-7003-2 11695 -
11695-7003-3 11695 -
11695-7004-0 11695 -
11695-7004-1 11695 -
11695-7004-2 11695 -
11695-7005-0 11695 -
11695-7005-1 11695 -
11695-7005-2 11695 -
11695-7006-0 11695 -
11695-7006-1 11695 -
11695-7006-2 11695 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

Data Sources & Revision History

Every non-trivial field is expected to include provenance and update timestamps.

Official 58 Clinical 2 Manufacturer 0 Marketing 0
Current Field Facts
  • overdose_info: Overdose can cause severe GI bleeding and kidney injury. Seek emergency veterinary care. (Clinical, 2026-02-12)
  • storage_handling: Store at room temperature in a dry place. (Clinical, 2026-02-12)
  • contraindications: Avoid combining with other NSAIDs or corticosteroids. Use caution with kidney/liver disease or GI ulcer history. (Official, 2026-02-12)
  • side_effects: GI upset (vomiting/diarrhea), decreased appetite, lethargy. Rare: ulceration or liver enzyme elevations. (Official, 2026-02-12)
  • usage: NSAID used for pain and inflammation (commonly osteoarthritis and post-operative pain in dogs). (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Carprofen Chewable Tablets
RX
Carprofen
Scored Chewable Tablets Oral
Dechra Veterinary Products LLC ANADA 200-575 W Aug 26, 2025
Novox® Caplets Carprofen Caplets
RX
Carprofen
Caplet Oral
Dechra Veterinary Products LLC ANADA 200-366 W Aug 26, 2025
Carprofen Tablets
RX
Carprofen
Flavored Tablets Oral
Felix Pharmaceuticals Pvt. Ltd. ANADA 200-767 Approved Mar 20, 2025
Carprofen Flavored Tablets
RX
Carprofen
Tablet Oral
Ajenat Pharmaceuticals LLC ANADA 200-578 Approved Feb 24, 2025
Vetprofen™
RX
Carprofen
Caplet Oral
Ajenat Pharmaceuticals LLC ANADA 200-397 Approved Feb 24, 2025
Carofenvet™
RX
Carprofen
Injectable Solution Subcutaneous
Cronus Pharma Specialities India Private Ltd. ANADA 200-762 Approved Feb 5, 2025
Carprofen Chewable Tablets
RX
Carprofen
Chewable Tablets Oral
Cronus Pharma Specialities India Private Ltd. ANADA 200-687 Approved Feb 5, 2025
Carprofen
RX
Carprofen
Injectable Solution Subcutaneous
Felix Pharmaceuticals Pvt. Ltd. ANADA 200-777 Approved Jan 16, 2025
CARPROFEN Chewable Tablets
RX
Carprofen
Chewable Tablets Oral
Felix Pharmaceuticals Pvt. Ltd. ANADA 200-706 Approved Jan 13, 2025
CARPROFEN Soft Chewable Tablets
RX
Carprofen
Chewable Tablets Oral
Felix Pharmaceuticals Pvt. Ltd. ANADA 200-795 Approved Oct 1, 2024
Carprofen
RX
Carprofen
Chewable Tablets Oral
ZYVET AH, Inc. ANADA 200-739 Approved Aug 17, 2023
CARPRIEVE®
RX
Carprofen
Tablet Oral
Norbrook Laboratories, Ltd. ANADA 200-498 Approved Apr 20, 2023
Carprofen Tablets
RX
Carprofen
Caplet Oral
Felix Pharmaceuticals Pvt. Ltd. ANADA 200-732 Approved Feb 1, 2023
Carprieve® Injection
RX
Carprofen
Injectable Solution Subcutaneous
Norbrook Laboratories, Ltd. ANADA 200-520 Approved Dec 16, 2022
Rimadyl® Sterile Injectable Solution
RX
Carprofen
Liquid (Solution) Subcutaneous
Zoetis Inc. NADA 141-199 Approved Mar 21, 2022
Carprofen Tablets
RX
Carprofen
Caplet Oral
Dechra Veterinary Products LLC ANADA 200-703 Approved Aug 2, 2021
Carprofen Tablets
RX
Carprofen
Flavored Tablets Oral
Dechra Veterinary Products LLC ANADA 200-681 Approved Sep 1, 2020
Carprofen
RX
Carprofen
Chewable Tablets Oral
Dechra Veterinary Products LLC ANADA 200-490 Approved Oct 1, 2019
Rimadyl® Caplets
RX
Carprofen
Caplet Oral
Zoetis Inc. NADA 141-053 Approved Aug 27, 2019
Rimadyl® Chewable Tablets
RX
Carprofen
Tablet (Chewable) Oral
Zoetis Inc. NADA 141-111 Approved Jul 1, 2019
Carprofen Sterile Injectable Solution
RX
Carprofen
Injectable Solution Subcutaneous
Dechra Veterinary Products LLC ANADA 200-522 Approved Jun 12, 2018
Carprieve® Chewable Tablets
RX
Carprofen
Chewable Tablets Oral
Norbrook Laboratories, Ltd. ANADA 200-595 Approved May 1, 2017
Carprofen Injection
RX
Carprofen
Injectable Solution Subcutaneous
Accord Healthcare, Inc. ANADA 200-593 Approved May 1, 2017
quellin®
RX
Carprofen
Soft Chewable Tablet Oral
Elanco US Inc. ANADA 200-555 Approved Jun 1, 2016

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
25 mg, 75 mg, and 100 mg tablets
Label highlights
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Tablets are scored and dosage should be calculated in half-tablet increments
Limitations
Federal Law restricts this drug to use by or on the order of a licensed veterinarian

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
Each caplet contains 25, 75, or 100 milligrams (mg) carprofen.
Dogs
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries.
Dosage
2 milligram per pound of body weight once daily or 1 milligram per pound twice daily.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
25 mg, 75 mg, or 100 mg of carprofen per tablet
Dogs
Indication

For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.

Dosage

2 milligram per pound (4.4 mg/kg) of body weight once daily or 1 milligram per pound twice daily.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Label highlights
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2. mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Tablets are scored and dosage should be calculated in half-tablet increments
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
Each caplet or chewable tablet contains 25, 75, or 100 milligrams (mg) carprofen.
Dogs
Indication
For the control of postoperative pain associated with soft tissue and orthopedic surgery. For the relief of pain and inflammation associated with osteoarthritis
Dosage
2 milligram per pound of body weight once daily or 1 milligram per pound twice daily.
Limitations
For the control of postoperative pain, administer approximately 2 hours before the procedure. Federal law restricts this drug to use by or on the order of a licensed veterinarian

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
50 mg/mL
Dogs
Indication

For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.

Dosage

The recommended dosage for subcutaneous administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as either 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For control of postoperative pain, administer approximately 2 hours before the procedure.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
25 mg, 37.5 mg, 50 mg, 75 mg, and 100 mg of carprofen per tablet
Dogs
Indication

For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.

Dosage

The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. For scored tablets, dosage should be calculated in half-tablet increments.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
50 mg/mL
Dogs
Indication

For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.

Dosage

The recommended dosage for subcutaneous administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as either 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For control of postoperative pain, administer approximately 2 hours before procedure.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
25 mg, 75 mg, and 100 mg of carprofen per tablet
Dogs
Indication

For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.

Dosage

The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. For scored tablets, dosage should be calculated in half-tablet increments.

Limitations

FDA page: Open in Animal Drugs @ FDA

Composition / specifications
25 mg, 75 mg, or 100 mg of carprofen per tablet
Dogs
Indication

For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.

Dosage

The recommended dosage for oral administration to dogs is 2 mg/lb of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
25 mg, 75 mg and 100 mg of carprofen per tablet
Dogs
Indication

For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.

Dosage

The recommended dosage for oral administration to dogs is 2 mg/lb of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Carprofen chewable tablets are scored and dosage should be calculated in half-tablet increments.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
Each caplet or chewable tablet contains 25, 75, or 100 milligrams (mg) carprofen.
Dogs
Indication
Carprofen is indicated for the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries In dogs.
Dosage
2 milligram per pound of body weight once daily or 1 milligram per pound twice daily.
Limitations
For use in dogs only. Do not use in cats. Carprofen should not be used in dogs exhibiting previous hypersensitivity to carprofen.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
25 mg, 75 mg, or 100 mg of carprofen per caplet
Dogs
Indication

For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.

Dosage

The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
Each milliliter (mL) contains 50 milligrams (mg) of carprofen.
Label highlights
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.

Dosage
The recommended dosage for subcutaneous administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as either 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For control of postoperative pain, administer approximately 2 hours before the procedure.

Limitations

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
Each milliliter of solution contains 50 milligrams carprofen.
Dogs
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries.
Dosage
2 milligram per pound (4.4 milligrams per kilogram) body weight once daily or 1 milligram per pound (2.2 milligrams per kilogram) body weight twice daily, by subcutaneous injection.
Limitations
For use in dogs only. Do not use in cats. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For the control of postoperative pain, administer approximately 2 hours before the procedure.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
25, 75, or 100 mg carprofen per caplet
Dogs
Indication

For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.

Dosage

The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
25 mg, 75 mg, or 100 mg of carprofen per tablet
Dogs
Indication

For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.

Dosage

The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Tablets are scored and dosage should be calculated in half-tablet increments.

Limitations

FDA page: Open in Animal Drugs @ FDA

Composition / specifications
25 mg, 75 mg, and 100 mg of carprofen per tablet
Dogs
Indication

For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue
and orthopedic surgeries in dogs.

Dosage

The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Tablets are scored and dosage should be calculated in half-tablet increments.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
Each caplet or chewable tablet contains 25, 75, or 100 milligrams (mg) carprofen.
Dogs
Indication
For the control of postoperative pain associated with soft tissue and orthopedic surgery. For the relief of pain and inflammation associated with osteoarthritis.
Dosage
2 milligram per pound (4.4 mg/kg) of body weight once daily or 1 milligram per pound twice daily.
Limitations
For use in dogs only. Not for use in cats. For the control of postoperative pain, administer approximately 2 hours before the procedure. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
Each caplet or chewable tablet contains 25, 75, or 100 milligrams (mg) carprofen.
Dogs
Indication
Rimadyl is indicated for the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
2 milligram per pound of body weight once daily or 1 milligram per pound twice daily.
Limitations
For use in dogs only. Do not use in cats. For the control of postoperative pain, administer approximately 2 hours before the procedure Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
50 mg/mL
Label highlights
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for subcutaneous administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as either 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For control of postoperative pain, administer approximately 2 hours before the procedure.
Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
25, 75, and 100 mg tablet strengths
Dogs
Indication

For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.

Dosage

The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Tablets are scored and dosage should be calculated in half-tablet increments.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
50 mg/mL
Dogs
Indication

For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries.

Dosage

2 mg/lb. (4.4 mg/kg) body weight once daily or 1 mg/lb. pound (2.2 mg/kg) body weight twice daily.

Limitations

For use in dogs only. Do not use in cats. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For the control of postoperative pain, administer approximately 2 hours before the procedure.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
25, 75, and 100 mg
Label highlights
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs
Dosage
2 mg per pound (lb) of body weight once daily or 1 mg/lb twice daily for the control of postoperative pain; administer approximately 2 hours before procedure
Limitations
Federal Law restricts this drug to use by or on the order of a licensed veterinarian

FDA page: Open in Animal Drugs @ FDA

Official Documents (FDA)

Direct links to FDA-hosted PDFs and SPL packages (when available).

Documents
  • Summary
    For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This application provides for the additional indication for the control of postoperative pain associated with soft tissue and orthopedic surgeries.
  • Summary
    For the relief of pain and inflammation associated with osteoarthritis in dogs.
  • Labeling UCM050400.pdf
  • Labeling UCM050400.pdf
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplement to NADA 141-199 provides revisions to 21CFR 522.312 (2) Indications for Use. To add a claim for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
  • Summary
    provides for the addition of a once daily administration of 2 mg/lb (4.4 mg/kg) of body weight in addition to a twice daily administration of 1 mg/lb (2.2 mg/kg) by subcutaneous injection.
  • Summary
    Rimadyl® Injectable is indicated for the relief of pain and inflammation associated with

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    To add a claim for the control of postoperative pain associated with soft tissue and orthopedic surgery in dogs.
  • Summary
    This supplement provides for flexibility in administration of the total daily dose of Rimadyl® caplets. The drug may be administered orally at 2 milligrams per pound of body weight once daily or 1 milligram per pound of body weight twice daily.
  • Summary
    RIMADYL® is indicated for the relief of pain and inflammation in dogs. RIMADYL was shown to be clinically effective for the reflief of signs associated with osteoarthritis in dogs.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For an additional claim for carprofen chewable tablets for the control of postoperative pain associated with soft tissue and orthopedic surgery in dogs.
  • Summary
    This supplement provides for flexibility in administration of the total daily dose of Rimadyl® Chewable Tablets. The drug may be administered orally at 2 milligrams per pound of body weight once daily or 1 milligram per pound of body weight twice daily
  • Summary
    Rimadyl® chewable tablets are indicated for the relief of pain and inflammation associated with osteoarthritis in dogs.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Usage

NSAID used for pain and inflammation (commonly osteoarthritis and post-operative pain in dogs).

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Avoid combining with other NSAIDs or corticosteroids. Use caution with kidney/liver disease or GI ulcer history.

Side Effects

GI upset (vomiting/diarrhea), decreased appetite, lethargy. Rare: ulceration or liver enzyme elevations.

Source: FDA openFDA • Reference

Top Reported Reactions (openFDA)

Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).

Dog
Digestive
Vomiting (2628) Diarrhea (1437) Loss of appetite (958) Diarrhea (17) Diarrhea (17) Diarrhea (17) Diarrhea (17) Vomiting (17) Vomiting (17) Vomiting (17) Vomiting (17) Diarrhea (16) Diarrhea (16) Vomiting (16) Vomiting (14)
Neurologic
Tiredness (lethargy) (1364) Tiredness (lethargy) (22) Tiredness (lethargy) (22) Tiredness (lethargy) (22) Tiredness (lethargy) (22) Tiredness (lethargy) (21) Tiredness (lethargy) (21)
Other
Elevated alanine aminotransferase (1287) Death by euthanasia (1046) Not eating (840) Elevated serum alkaline phosphatase (819) Death by euthanasia (17) Death by euthanasia (17) Death by euthanasia (17) Death by euthanasia (17) Death by euthanasia (16) Death by euthanasia (16) Not eating (15) Not eating (15) Not eating (15) Not eating (15) Medication error NOS (14) Medication error NOS (14) Medication error NOS (14) Medication error NOS (14) Medication error NOS (14) Not eating (14) Not eating (14) Medication error NOS (13) Panting (13) Panting (13) Panting (13) Panting (13) Panting (13) Death (11) Death (11) Death (11) Death (11) Panting (11) Death (10) Death (10)
Cat
Digestive
Vomiting (18) Diarrhea (7)
Neurologic
Tiredness (lethargy) (12)
Other
Accidental exposure (15) Death by euthanasia (7) Elevated creatinine (6) Hyperglycaemia (6) Medication error (6) Accidental exposure (1) Accidental exposure (1) Accidental exposure (1) Accidental exposure (1) Accidental exposure (1) Death by euthanasia (1) Death by euthanasia (1) Death by euthanasia (1) Death by euthanasia (1) Death by euthanasia (1) Death by euthanasia (1) Dilated pupils (1) Dilated pupils (1) Dilated pupils (1) Dilated pupils (1) Dilated pupils (1) General illness (1) General illness (1) General illness (1) General illness (1) General illness (1) General illness (1) Hyperglycaemia (1) Hyperglycaemia (1) Hyperglycaemia (1) Hyperglycaemia (1) Hyperglycaemia (1) Hyperglycaemia (1) Intentional misuse (1) Intentional misuse (1) Intentional misuse (1) Intentional misuse (1) Intentional misuse (1) Intentional misuse (1)

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Retriever - Golden, Male, 5 year, 36 kilogram • Drug: MSK, Tablet, chewable, Oral, Frequency: 1 per day • Reactions: Vomiting • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-056005
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 5.00 Year
  • Weight: 36.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Frequency: 1 per day
Reactions Reported:
Vomiting
Outcomes: Recovered/Normal

Dog, Dog (unknown), Male, 14 year, 33.566 kilogram • Drug: MSK, Solution/drops, Unknown • Reactions: Hind limb paresis • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055509
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 14.00 Year
  • Weight: 33.566 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Solution/drops
Reactions Reported:
Hind limb paresis
Outcomes: Ongoing

Dog, Pit Bull, Female, 8.5 year, 23.587 kilogram • Drug: MSK, Tablet, Oral, Dose: 1 tablet per dose, Frequency: 1 per day • Reactions: Elevated alanine aminotransferase, Elevated aspartate aminotransferase, Elevated gamma-glutamyl transferase, Low thyroxine • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-055526
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 8.50 Year
  • Weight: 23.587 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 1 tablet per dose
  • Frequency: 1 per day
Reactions Reported:
Elevated alanine aminotransferase Elevated aspartate aminotransferase Elevated gamma-glutamyl transferase Low thyroxine
Outcomes: Outcome Unknown

Dog, ['Dachshund - Standard Long-haired', 'Dog (unknown)'], Male, 12 year, 8.936 kilogram • Drug: MSK, Unknown • Reactions: Fever, Panting, Swollen limb, Localised pain NOS, Paralysis NOS • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055637
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 12.00 Year
  • Weight: 8.936 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Fever Panting Swollen limb Localised pain NOS Paralysis NOS
Outcomes: Ongoing

Dog, ['Shepherd Dog - German', 'Dog (unknown)'], Female, 2.5 year • Drug: MSK, Subcutaneous, Dose: 0.95 mL per animal • Reactions: Neutropenia, Eosinophilia, Lymphocytosis, Enamel disorder, Tooth disorder • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-055809
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 2.50 Year
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Dose: 0.95 mL per animal
Reactions Reported:
Neutropenia Eosinophilia Lymphocytosis Enamel disorder Tooth disorder
Outcomes: Outcome Unknown

Cat, Cat (unknown), Female, 4.05 kilogram • Drug: MSK, Tablet, Oral, Dose: 50 Milligram per animal, Frequency: 24 per hour • Reactions: Hyperglycaemia • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-054116
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Weight: 4.050 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 50 Milligram per animal
  • Frequency: 24 per hour
Reactions Reported:
Hyperglycaemia
Outcomes: Outcome Unknown

Cat, Cat (other), Female • Drug: MSK, Injection, Unknown • Reactions: General illness, Death by euthanasia, Intentional misuse • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2025-US-050538
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Injection
Reactions Reported:
General illness Death by euthanasia Intentional misuse
Outcomes: Euthanized

Cat, ['Cat (unknown)', 'Cat (unknown)'], Unknown, 9 kilogram • Drug: MSK, Tablet, chewable, Oral • Reactions: Dilated pupils, Accidental exposure • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-050545
  • Serious AE: No
  • Treated For AE: No
  • Sex: Unknown
  • Weight: 9.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
Reactions Reported:
Dilated pupils Accidental exposure
Outcomes: Recovered/Normal

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

Overdose can cause severe GI bleeding and kidney injury. Seek emergency veterinary care.

Storage & Handling

Store at room temperature in a dry place.

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