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Meds A-Z

Tylosin

Detailed information about Tylosin

Official label facts Owner quick guide first Marketing clearly labeled
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Pet Owner Quick Guide

Start here: what this medicine is for, what it does, and when it's usually needed.

Usually used for:

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, control of swine dysentery associated with Brachyspira hyodysenteriae , and control of porcine proliferative enteropathies (PPE, il...

What it does:

Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pn...

When it's needed:

As tylosin phosphate. Withdraw 15 days before slaughter. As tylosin phosphate. Feed continuously. Only medicated water should be available to the birds.

Call your vet sooner if you notice:

  • As tylosin phosphate. Withdraw 15 days before slaughter. As tylosin phosphate. Feed continuously. Only medicated water should be available to the birds.

Commonly reported reactions:

  • (2 reports)
  • (1 reports)
  • (1 reports)

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
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Tylosin

Tylosin

Drug type: Generic ingredient • Branded profile FDA branded products available

Species: Both

Manufacturer: Huvepharma EOOD

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Huvepharma EOOD
Form: Implant, Implant (Pellet), Injectable Solution, Injection, Medicated Feed, Soluble Powder
Identifiers:
ANADA: 200221 ANADA: 200224 ANADA: 200346 ANADA: 200375 ANADA: 200424 ANADA: 200427 ANADA: 200430 ANADA: 200455 ANADA: 200473 ANADA: 200480 ANADA: 200484 ANADA: 200508 ANADA: 200530 ANADA: 200531 ANADA: 200532 ANADA: 200533 ANADA: 200534 ANADA: 200535 ANADA: 200544 ANADA: 200547
Source metadata:

Warnings / Contraindications

As tylosin phosphate. Withdraw 15 days before slaughter. As tylosin phosphate. Feed continuously. Only medicated water should be available to the birds.

  • High: As tylosin phosphate. Withdraw 15 days before slaughter. As tylosin phosphate. Feed continuously. Only medicated water should be available to the birds.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
9
Species represented
2
Most Reported Reactions
Reaction Cases Species Serious cases
2 Cat, Dog 2
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Cat 1
1 Cat 1
1 Dog 1

Species coverage: Dog (18) Cat (14)

View detailed reaction table
Reaction Species Seriousness Frequency Reports
Dog Non-serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Non-serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Non-serious - 1
Cat Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Cat Non-serious - 1
Dog Non-serious - 1
Cat Non-serious - 1
Dog Non-serious - 1
Cat Non-serious - 1
Cat Non-serious - 1
Dog Serious - 1
Cat Non-serious - 1
Cat Non-serious - 1
Dog Serious - 1
Dog Non-serious - 1
Cat Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Serious - 1
Dog Non-serious - 1
Dog Serious - 1
Cat Non-serious - 1
Dog Non-serious - 1
Cat Non-serious - 1
Source metadata:

Storage & Handling

No storage/handling guidance is linked yet.

Source metadata: No source yet.

Documents

Official label facts are separated from secondary summaries.

Official documents: 418 • Secondary summaries: 0

Official label facts
Secondary summaries

No source yet.

Promotional Materials (Marketing)

This content is marketing material and not clinical guidance.

No marketing assets are linked yet.

No source yet.

Source metadata: No source yet.
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Technical appendix (vet reference)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 16, 2026, 11:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:22 AM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: Actogain™ 45/Rumensin®/Tylan® Actogain™ 45/Rumensin®/Tylan®/MGA® Actogain™ 45/Rumensin®/Tylovet® 100 Actogain™ 45/Rumensin®/Tylovet® 100/MGA® Actogain™ and Monovet® and Tylan™ Actogain™ and Monovet® and Tylan™ and MGA® Actogain™ and Monovet® and Tylovet® Actogain™ and Monovet® and Tylovet® and MGA® Alley Tylan®-10 Premix BiloVet® Bovatec® / MGA® 100 / Tylan® Bovatec® / MGA® 100-200 Premix / Tylan® Bovatec® / MGA® 500 Liquid Premix / Tylan® Bovatec® / MGA® 200 / Tylan® CO-OP Tylan® 10 Premix Medicated Coban® / Tylan® Component® T-S with Tylan® Component® T-H with Tylan® Component™ E-C with Tylan™ Component™ E-S with Tylan™ Component™ E-C Component™ TE-200 with Tylan™ Component™ TE-H with Tylan™ Component™ TE-IH with Tylan™ Component™ TE-G Component™ TE-G with Tylan™ Component™ TE-S with Tylan™ Component™ TE-IS with Tylan™ Component™ TE-S Component™ TE-IS CycleGuard® and Monovet® and Tylovet® Deccox® and Monovet® and Tylan™ Deccox® and Monovet® and Tylovet® Deccox® and Rumensin™ and Tylan™ Deccox®, Rumensin™, and Tylovet® 100 Engain™ plus Tylan® Engain™ plus Tylovet® 100 Experior™ and Monovet® and Tylovet® Experior™ and Rumensin™ and Tylan™ FS Tylan® 40 Mix Med. Fasco Super Tylosin Premix Formica Premix-T Medicated Gilt Edge Tylan® Mix Good-Life Tylan® 10 Premix Gossett G-F Swine Premixes Baby Pig Premix HFA Tylosin-10 Plus Sulfa HeifermaX® 500 plus Bovatec® and Tylan™ HeifermaX™ 500 / Rumensin™ / Tylan™ Heifermax® 500/Zilmax®/Rumensin®/Tylan® Heifermax™ / Optaflexx® / Rumensin® / Tylan® Heifermax™ 500 Liquid Premix and Tylan® Heinold Tylan® 5 Sulfa Premix Tylan® 10 Sulfa-G Tylan® 5 Sulfa-G Tylan® 40 Sulfa-G Tylan® 20 Sulfa-G Hog-Grow-R-Mix-800 Hog Grow-R-Mix-4000 Hubbard Tylan® Plus Sulfa Premix Hy-Con Tylan® Premix Hy-Test Hy-Boost TY 5 Medicated Hygromix-Tylan® Premix Ingmands Swine Premix-T Medicated Kay Dee Tylan® 10 Premix-Med M & M Tylosin Premix MGA® 200 / Rumensin® / Tylan® MGA® 100 / Rumensin® / Tylan® MGA® and Bovatec® and Tylan™ MGA® and Experior™ and Monovet® and Tylovet® MGA® and Experior™ and Rumensin™ and Tylan™ MGA® and Monovet® and Tylan™ MGA® and Monovet® and Tylovet® MGA® and Rumensin™ and Tylan™ MGA® and Tylan™ MGA® plus Tylovet® 100 MGA®, Rumensin™ and Tylovet® 100 MGA®/ Bovatec®/ Tylovet® 100 McNess Custom Premix L200 Mill Co Medicator TS-40 Premix Mill Co-Medicator TY-4 Mill Co-Medicator TY-10 Monovet® and Tylan™ Monovet® and Tylovet® Monteban® / Tylan® Moormaboost TY 4000 Medicated NSI Tylosin 10 Premix Norco T-2 Pre-Pak Nutra-Blend Tylan® 10 Premix Nutra-Blend Tylan® 5 Sulfa Premix Tylan® 10 Sulfa Premix Tylan® 5 Sulfa Premix Tylan® 40 Sulfa Premix Tylan® 20 Sulfa Premix Optaflexx™ 45/Rumensin®/Tylovet® 100 Optaflexx™ 45/Rumensin®/Tylovet® 100/MGA® Optaflexx™ and Monovet® and Tylan™ and MGA® Optaflexx™ and Monovet® and Tylovet® and MGA® Optaflexx™ and Rumensin™ and Tylan™ Optaflexx™ and Rumensin™ and Tylan™and MGA® Optaflexx™and Monovet® and Tylan™ Optaflexx™and Monovet® and Tylovet® Optigrid® and Monovet® and Tylovet® Optigrid® and Monovet® and Tylovet® and CycleGuard® Optigrid® and Monovet® and Tylovet® and MGA® Paylean™ and Tylan™ Paylean™ and Tylovet® Pioneer Hog Care Premix Pro Mix T Medicated Medi-Flex T Tylan® Premix Purina® Hog Plus II Purina® Pork-Plus Medicated Purina® Tylan® 40 Plus Sulfamethazine Quali-Tech Tylan®-10 Premix Rumensin® plus Tylovet® 100 Rumensin™ and Tylan™ Rx-Link-Tylan® 1600 Seeco Inc T-10 Premix Seeco Tylan®-Sulfa 10 Premix Med. Simonsen Tylan® Vitamin Premix Supersweet Medipak Tylan® 10 Swine Med-A-Mix TS 8000 Premix Tylan® 10 Sulfa-G Tylan® 5 Sulfa-G Tylan® 40 Sulfa-G Tylan® 20 Sulfa-G Swine Premix 18586 Broiler Premix 18586 TYLAN™ 20 TYLAN™ 40 Thrifty Swine Mix Tylan 10 Premix Tylan 5 Premix Tylan 40 Premix Tylan 20 Premix Tylan 10 Sulfa-G Tylan 5 Sulfa-G Tylan 40 Sulfa-G Tylan 20 Sulfa-G Tylan 5, 10, 20 40 Premix Tylan Soluble™ Tylan® / Bio-Cox® Tylan® 10 Tylan® 10 Plus Tylan® 10 Premix Tylan® 10 Premix Tylan® 100 Premix Tylan® 40 Premix Tylan® 10 Premix Tylan® 20 Premix Tylan® 5 Premix Tylan® 40 Premix Tylan® 10 Sulfa-G Premix Tylan® 5 Sulfa-G Premix Tylan® 40 Sulfa-G Premix Tylan® 20 Sulfa-G Premix Tylan® 10 Sulfa-G Tylan® 20 Sulfa-G Quali-Tech Tylan®-Sulfa Premix 10 -10 Tylan® 5 Sulfa-G Tylan® 40 Sulfa-G Tylan® 10 Sulfa-G Tylan® 40 Sulfa-G Tylan® 5 Sulfa-G Tylan® 20 Sulfa-G Tylan® 10 Sulfa-G Tylan® 5 Sulfa-G Tylan® 40 Sulfa-G Tylan® 20 Sulfa-G Tylan® 10 Tylan® 5 Tylan® 40 Tylan® 20 Tylan® 100 Premix Tylan® 20 Sulfa-G Premix Tylan® 10 Sulfa-G Premix Tylan® 5 Sulfa-G Premix Tylan® 40 Sulfa-G Premix Tylan® 20 Sulfa-G Tylan® 40 Sulfa-G Tylan® 5 Sulfa-G Tylan® 10 Sulfa-G Tylan® 5 Sulfa Premix Tylan® 40 Tylan® 40 Sulfa-G Premix Tylan® 5 Sulfa-G Premix Tylan® 20 Sulfa-G Premix Tylan® 10 Sulfa-G Premix Tylan® 40 Sulfa-G Tylan® 20 Sulfa-G Tylan® 40 Sulfa-G Tylan® 5 Sulfa-G Tylan® 20 Sulfa-G Tylan® 10 Sulfa-G Tylan® 40 Sulfa-G™ Tylan® 10 Sulfa-G™ Tylan® 40 Tylan® 10 Tylan® 5 Premix Tylan® 5 Sulfa Premix Tylan® 5 Sulfa Premix Tylan® 10 Sulfa Premix Tylan® Injectable Tylan® Plus Neomycin Eye Powder Tylan® Plus Vitamins Tylan® Premix No.10 Tylan® Sulfa Tylan® Sulfa 10 G Tylan® Sulfa 5 G Tylan® Sulfa 40 G Tylan® Sulfa 20 G Tylan® Sulfa 10-10 Premix Medi-Flex T:S Tylan® Sulfa-G Tylan® plus Sacox® Tylan™ 5 Sulfa-G™ Tylan™ 10 Sulfa-G™ Tylan™ 20 Sulfa-G™ Tylan™ 40 Sulfa-G™ Tylan™ and Banminth® Tylocine Sulfa Tablets 50 Tylosin® / Hygromix Tylosin® 10 Premix Tylosin® 10 Type A Medicated Article Tylosin® 5 Type A Medicated Article Tylosin® 40 Type A Medicated Article Tylosin® 20 Type A Medicated Article Tylosin® Antibiotic Premix Tylosin® Premix 4 Tylovet® 100 plus Sacox® Tylovet® 200 mg/mL Injection Tylovet® 40 Tylovet® 100 Tylovet® Soluble Tylovet®100 plus Bio-cox® Tyson Tylan® Premix 1 Medicated Tyson Tylan® Premix 5 Medicated Tyson Tylan® Premix 2 Medicated V.P.O. Tylan® Plus Sulfa Vigorena Feeds Hy-Ty Premix Vita Plus N-Richer Pig Grower Walnut Grove 4x4 Add-Mix T Waynextra For Swine Webel Tylan® Premix Zilmax® and Rumensin™ and Tylan™ Zilmax® and Rumensin™ and Tylan™ and MGA® Zilmax®/Rumensin®/Tylovet® 100 Zilmax®/Rumensin®/Tylovet® 100/MGA®
Case-reported brands (openFDA): MSK
Catalog species: Both FDA-labeled species: Beef, Beef And Non-Lactating Dairy, Beef calves at least 45 days old and up to 400 lbs of body weight, Beef fed In confinement for slaughter, Beef heifers fed in confinement for slaughter, Beef steers fed in confinement for slaughter, Broilers, Calves, Cattle, Chicken, Dairy, Excluding turkeys producing eggs for human consumption, Fed in confinement for slaughter, Finishing, Growing beef heifers fed in confinement for slaughter, Growing beef steers and heifers fed in confinement for slaughter, Growing beef steers and heifers on pasture (stocker, Growing beef steers fed in confinement for slaughter, Growing-Finishing Cattle Being Fed In Confinement For Slaughter, Heifers fed in confinement for slaughter, Honey Bees, No use class stated or implied, Not laying eggs for human consumption, Replacements, Swine
Rx/OTC: OTC, RX, VFD
Form/route: Implant, Implant (Pellet), Injectable Solution, Injection, Medicated Feed, Soluble Powder, Type A Medicated Article, Type A medicated articles for use in the manufacture of Type B and Type C medicated feeds, Type A medicated articles to be used in the manufacture of Type C medicated feeds Intramuscular, Oral, Subcutaneous
Applications: NADA 141-172 • ANADA 200-561 • ANADA 200-562 • ANADA 200-585 • ANADA 200-583 • ANADA 200-533 • ANADA 200-375 • ANADA 200-480 • ANADA 200-424 • NADA 138-792 • ANADA 200-534 • ANADA 200-566 • ANADA 200-567 • ANADA 200-531 • NADA 141-280 • ANADA 200-547 • ANADA 200-544 • NADA 138-992 • NADA 141-149 • NADA 46415 • NADA 91749 • ANADA 200-808 • NADA 138-955 • NADA 141-591 • ANADA 200-558 • ANADA 200-584 • NADA 138-870 • NADA 139-192 • ANADA 200-724 • NADA 141-512 • NADA 110-315 • ANADA 200-221 • ANADA 200-530 • ANADA 200-346 • ANADA 200-224 • ANADA 200-455 • ANADA 200-508 • ANADA 200-473 • ANADA 200-484 • NADA 104-646 • ANADA 200-643 • ANADA 200-642 • ANADA 200-685 • ANADA 200-686 • ANADA 200-676 • ANADA 200-678 • NADA 41275 • ANADA 200-661 • ANADA 200-660 • ANADA 200-430 • ANADA 200-651 • ANADA 200-649 • ANADA 200-656 • ANADA 200-653 • ANADA 200-650 • ANADA 200-648 • ANADA 200-647 • ANADA 200-646 • ANADA 200-645 • ANADA 200-644 • NADA 13076 • NADA 139-488 • NADA 96837 • ANADA 200-569 • ANADA 200-570 • NADA 110-047 • ANADA 200-427 • ANADA 200-535 • ANADA 200-532 • NADA 141-276 • NADA 141-224 • NADA 141-233 • ANADA 200-580 • NADA 138-904 • NADA 98431 • NADA 96512 • NADA 141-164 • NADA 125-226 • NADA 96839 • NADA 44013 • NADA 99098 • NADA 91582 • NADA 110-045 • NADA 131-537 • NADA 127-506 • NADA 108-484 • NADA 96162 • NADA 94402 • NADA 96161 • NADA 13388 • NADA 98687 • NADA 91465 • NADA 111-814 • NADA 100-991 • NADA 101-906 • NADA 101-905 • NADA 141-170 • NADA 95953 • NADA 49890 • NADA 102-717 • NADA 122-158 • NADA 129-161 • NADA 91783 • NADA 42489 • NADA 43387 • NADA 42660 • NADA 99767 • NADA 97980 • NADA 102-590 • NADA 100-352 • NADA 107-002 • NADA 96776 • NADA 100-128 • NADA 97615 • NADA 42755 • NADA 119-261 • NADA 97289 • NADA 15166 • NADA 93518 • NADA 97567 • NADA 107-958 • NADA 133-833 • NADA 138-187 • NADA 140-680 • NADA 140-531 • NADA 138-453 • NADA 138-454 • NADA 139-301 • NADA 139-601 • NADA 140-820 • NADA 97981 • NADA 111-069 • NADA 140-530 • NADA 109-816 • NADA 128-835 • NADA 129-159 • NADA 130-465 • NADA 48645 • NADA 103-089 • NADA 131-957 • NADA 137-051 • NADA 139-600 • NADA 140-681 • NADA 129-646 • NADA 138-342 • NADA 107-957 • NADA 127-507 • NADA 96780 • NADA 95551 • NADA 128-411 • NADA 128-255 • NADA 141-198 • NADA 12585 • NADA 31962 • NADA 13029 • NADA 13162 • NADA 127-826 • NADA 98156 • NADA 99561 • NADA 131-956 • NADA 131-958 • NADA 138-343 • NADA 30330 • NADA 121-200 • NADA 111-637 • NADA 95628 • NADA 12548 • NADA 45690 • NADA 121-290 • NADA 100-556 • NADA 97287 • NADA 100-127 • NADA 98595 • NADA 99468 • NADA 116-196
Documents: 121 (FOI: 117) • SPL: 297 Label highlights Official documents
Safety (openFDA)
Top reactions: Dog 26 Cat 8 View
Case summaries: 10 (showing 8) View
openFDA reports are unverified and do not prove causation.

Explore
Linked using: Fda_Label (0.95), Fda_Label (0.95), Fda_Label (0.95)

Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • As tylosin phosphate. Withdraw 15 days before slaughter. As tylosin phosphate. Feed continuously. Only medicated water should be available to the birds. (Contraindication, High)
Top reaction signals
Abnormal cytology (1) Behavioural disorder NOS (1) Behavioural disorder NOS (1) Blood in urine (1) Cushings disease NOS (1) Dehydration (1) Diarrhoea (1) Difficulty to rise (1) Elevated blood urea nitrogen (BUN) (1) Elevated serum alkaline phosphatase (ALP) (1) Elevated temperature (1) Emesis (multiple) (1) Enlarged liver (1) Glucosuria (1) Hypoalbuminaemia (1) Inappetence (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
ANADA: 200221 ANADA: 200224 ANADA: 200346 ANADA: 200375 ANADA: 200424 ANADA: 200427 ANADA: 200430 ANADA: 200455 ANADA: 200473 ANADA: 200480 ANADA: 200484 ANADA: 200508 ANADA: 200530 ANADA: 200531 ANADA: 200532 ANADA: 200533 ANADA: 200534 ANADA: 200535 ANADA: 200544 ANADA: 200547 ANADA: 200558 ANADA: 200561 ANADA: 200562 ANADA: 200566
Package NDC Product NDC Form / Route Status
11311-799-25 11311 -
13985-710-05 13985 -
13985-710-10 13985 -
23243-2220-1 23243 -
23243-2350-1 23243 -
23243-2355-1 23243 -
46066-504-47 46066 -
46066-504-48 46066 -
58198-0040-1 58198 -
58198-0099-1 58198 -
58198-0205-1 58198 -
58198-0206-3 58198 -
58198-0206-5 58198 -
58198-0369-2 58198 -
58198-0507-2 58198 -
58198-0508-2 58198 -
58198-0511-1 58198 -
58198-0513-1 58198 -
58198-0904-2 58198 -
58198-1300-1 58198 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

  • ucm117246.pdf • FOI summary • Official • Feb. 9, 2026
    FDA FOI summary for application 141172
  • ucm117249.pdf • FOI summary • Official • Feb. 9, 2026
    FDA FOI summary for application 141172
  • ucm117251.pdf • FOI summary • Official • Feb. 9, 2026
    FDA FOI summary for application 141172
  • UCM198151.pdf • FOI summary • Official • Feb. 9, 2026
    FDA FOI summary for application 141172
  • UCM461134.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 200585
  • UCM461126.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 200583
  • UCM409022.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 200567
  • UCM409016.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 200566
  • UCM409000.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 200562
  • UCM408914.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 200561
  • UCM367496.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 200547
  • UCM363845.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 200544
  • UCM338174.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 200534
  • UCM351227.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 200533
  • UCM351217.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 200531
  • UCM210550.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 200480
  • UCM061362.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 200424
  • ucm091534.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 200424
  • ucm059307.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 200375
  • UCM279076.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 200375
  • ucm062336.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 141280
  • UCM433793.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 141280
  • UCM477998.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 138792
  • N138792_Supp_6_29_1994..pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 138792
  • ucm069884.pdf • FOI summary • Official • Nov. 5, 2025
    FDA FOI summary for application 138792
  • UCM472703.pdf • FOI summary • Official • Oct. 15, 2025
    FDA FOI summary for application 138992
  • UCM508345.pdf • FOI summary • Official • Oct. 15, 2025
    FDA FOI summary for application 138992
  • ucm117192.pdf • FOI summary • Official • Oct. 8, 2025
    FDA FOI summary for application 141149
  • FOI Summary oA 200-808 Approved July 8, 2025.pdf • FOI summary • Official • July 31, 2025
    FDA FOI summary for application 200808
  • UCM472700.pdf • FOI summary • Official • Feb. 24, 2025
    FDA FOI summary for application 138955
  • FOI Summary oN 141-591 Approved October 25, 2024.pdf • FOI summary • Official • Nov. 22, 2024
    FDA FOI summary for application 141591
  • UCM461130.pdf • FOI summary • Official • Nov. 12, 2024
    FDA FOI summary for application 200584
  • UCM408904.pdf • FOI summary • Official • Nov. 12, 2024
    FDA FOI summary for application 200558
  • UCM472688.pdf • FOI summary • Official • Nov. 12, 2024
    FDA FOI summary for application 138870
  • N138870_Supp_6_29_1994.pdf • FOI summary • Official • Nov. 12, 2024
    FDA FOI summary for application 138870
  • ucm111225.pdf • FOI summary • Official • Nov. 12, 2024
    FDA FOI summary for application 138870
  • UCM196103.pdf • FOI summary • Official • Nov. 12, 2024
    FDA FOI summary for application 138870
  • FOI Summary oA 200-724-A-0000 Approved July 19, 2022.pdf • FOI summary • Official • Oct. 8, 2024
    FDA FOI summary for application 200724
  • FOI Summary oN 141-512 Approved May 21, 2019.pdf • FOI summary • Official • Aug. 27, 2024
    FDA FOI summary for application 141512
  • A200221_Orig_3_20_1997.pdf • FOI summary • Official • July 3, 2024
    FDA FOI summary for application 200221

Data Sources & Revision History

Every non-trivial field is expected to include provenance and update timestamps.

Official 83 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: As tylosin phosphate. Withdraw 15 days before slaughter. As tylosin phosphate. Feed continuously. Only medicated water should be available to the birds. (Official, 2026-02-12)
  • side_effects: Top reported reactions (openFDA): Diarrhoea, Vomiting, Death by euthanasia, Lethargy (see also Central nervous system depression in Neurological), Other abnorm… (Official, 2026-02-12)
  • usage: Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; p… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Paylean™ and Tylan™
VFD
Ractopamine Hydrochloride Tylosin Phosphate
Type A Medicated Article Oral
Elanco US Inc. NADA 141-172 Approved Feb 9, 2026
Actogain™ 45/Rumensin®/Tylan®
VFD
Monensin Ractopamine Hydrochloride Tylosin Phosphate
Type A Medicated Article Oral
Phibro Animal Health Corp. ANADA 200-561 Approved Nov 5, 2025
Actogain™ 45/Rumensin®/Tylan®/MGA®
VFD
Melengestrol Acetate Monensin Ractopamine Hydrochloride Tylosin Phosphate
Type A Medicated Article Oral
Phibro Animal Health Corp. ANADA 200-562 Approved Nov 5, 2025
Actogain™ 45/Rumensin®/Tylovet® 100
VFD
Monensin Ractopamine Hydrochloride Tylosin Phosphate
Medicated Feed Oral
Phibro Animal Health Corp. ANADA 200-585 Approved Nov 5, 2025
Actogain™ 45/Rumensin®/Tylovet® 100/MGA®
OTC
Melengestrol Acetate Monensin Ractopamine Hydrochloride Tylosin Phosphate
Type A Medicated Article Oral
Phibro Animal Health Corp. ANADA 200-583 Approved Nov 5, 2025
Deccox®, Rumensin™, and Tylovet® 100
VFD
Decoquinate Monensin Tylosin Phosphate
Medicated Feed Oral
Huvepharma EOOD ANADA 200-533 Approved Nov 5, 2025
HeifermaX™ 500 / Rumensin™ / Tylan™
VFD
Melengestrol Acetate Monensin Tylosin Phosphate
Type A Medicated Article Oral
Elanco US Inc. ANADA 200-375 Approved Nov 5, 2025
Heifermax® 500/Zilmax®/Rumensin®/Tylan®
VFD
Melengestrol Acetate Monensin Tylosin Phosphate Zilpaterol
Type A Medicated Article Oral
Elanco US Inc. ANADA 200-480 Approved Nov 5, 2025
Heifermax™ / Optaflexx® / Rumensin® / Tylan®
VFD
Melengestrol Acetate Monensin Ractopamine Hydrochloride Tylosin Phosphate
Type A Medicated Article Oral
Elanco US Inc. ANADA 200-424 Approved Nov 5, 2025
MGA® 200 / Rumensin® / Tylan® MGA® 100 / Rumensin® / Tylan®
OTC
Melengestrol Acetate Monensin Tylosin Phosphate
Medicated Feed Oral
Zoetis Inc. NADA 138-792 W Nov 5, 2025
MGA®, Rumensin™ and Tylovet® 100
VFD
Melengestrol Acetate Monensin Tylosin Phosphate
Type A Medicated Article Oral
Huvepharma EOOD ANADA 200-534 Approved Nov 5, 2025
Optaflexx™ 45/Rumensin®/Tylovet® 100
VFD
Monensin Ractopamine Hydrochloride Tylosin Phosphate
Type A Medicated Article Oral
Huvepharma EOOD ANADA 200-566 Approved Nov 5, 2025
Optaflexx™ 45/Rumensin®/Tylovet® 100/MGA®
VFD
Melengestrol Acetate Monensin Ractopamine Hydrochloride Tylosin Phosphate
Type A Medicated Article Oral
Huvepharma EOOD ANADA 200-567 Approved Nov 5, 2025
Rumensin® plus Tylovet® 100
VFD
Monensin Tylosin Phosphate
Medicated Feed Oral
Huvepharma EOOD ANADA 200-531 Approved Nov 5, 2025
Zilmax® and Rumensin™ and Tylan™ and MGA®
VFD
Melengestrol Acetate Monensin Tylosin Phosphate Zilpaterol Hydrochloride
Type A Medicated Article Oral
Intervet, Inc. NADA 141-280 Approved Nov 5, 2025
Zilmax®/Rumensin®/Tylovet® 100
VFD
Monensin Tylosin Phosphate Zilpaterol
Type A Medicated Article Oral
Huvepharma EOOD ANADA 200-547 Approved Nov 5, 2025
Zilmax®/Rumensin®/Tylovet® 100/MGA®
VFD
Melengestrol Acetate Monensin Tylosin Phosphate Zilpaterol
Type A Medicated Article Oral
Huvepharma EOOD ANADA 200-544 Approved Nov 5, 2025
MGA® and Bovatec® and Tylan™
VFD
Lasalocid sodium Melengestrol Acetate Tylosin Phosphate
Type A Medicated Article Oral
Phibro Animal Health Corp. NADA 138-992 Approved Oct 15, 2025
Deccox® and Rumensin™ and Tylan™
VFD
Decoquinate Monensin Tylosin
Type A medicated articles for use in the manufacture of Type B and Type C medicated feeds Oral
Phibro Animal Health Corp. NADA 141-149 Approved Oct 8, 2025
Tylan® 40
VFD
Tylosin Phosphate
Type A medicated articles to be used in the manufacture of Type C medicated feeds Oral
Phibro Animal Health Corp. NADA 46415 Approved Sep 16, 2025
Tylan® 40 Sulfa-G™ Tylan® 10 Sulfa-G™
VFD
Sulfamethazine Tylosin Phosphate
Type A medicated articles for use in the manufacture of Type B and Type C medicated feeds Oral
Phibro Animal Health Corp. NADA 91749 Approved Sep 16, 2025
MGA® and Experior™ and Monovet® and Tylovet®
VFD
Lubabegron Melengestrol Acetate Monensin Tylosin
Type A medicated articles to be used in the manufacture of Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-808 Approved Jul 31, 2025
Tylovet® 200 mg/mL Injection
RX
Tylosin
Injectable Solution Intramuscular
Huvepharma EOOD NADA 138-955 Approved Feb 24, 2025
MGA® and Experior™ and Rumensin™ and Tylan™
VFD
Lubabegron Melengestrol Acetate Monensin Tylosin Phosphate
Type A medicated articles to be used in the manufacture of Type C medicated feeds Oral
Elanco US Inc. NADA 141-591 Approved Nov 22, 2024
Engain™ plus Tylan®
VFD
Ractopamine Hydrochloride Tylosin Phosphate
Medicated Feed Oral
Phibro Animal Health Corp. ANADA 200-558 Approved Nov 12, 2024
Engain™ plus Tylovet® 100
VFD
Ractopamine Hydrochloride Tylosin Phosphate
Medicated Feed Oral
Phibro Animal Health Corp. ANADA 200-584 Approved Nov 12, 2024
MGA® and Rumensin™ and Tylan™
VFD
Melengestrol Acetate Monensin Tylosin Phosphate
Type A Medicated Article Oral
Phibro Animal Health Corp. NADA 138-870 Approved Nov 12, 2024
MGA® and Tylan™
VFD
Melengestrol Acetate Tylosin Phosphate
Type A Medicated Article Oral
Phibro Animal Health Corp. NADA 139-192 Approved Nov 12, 2024
Experior™ and Monovet® and Tylovet®
VFD
Lubabegron Monensin Tylosin
Type A medicated articles to be used in the manufacture of Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-724 Approved Oct 8, 2024
Experior™ and Rumensin™ and Tylan™
VFD
Lubabegron Monensin Tylosin Phosphate
Type A medicated articles for use in the manufacture of Type B and Type C medicated feeds Oral
Elanco US Inc. NADA 141-512 Approved Aug 27, 2024
Component™ E-C with Tylan™ Component™ E-S with Tylan™ Component™ E-C
RX
Estradiol Benzoate Progesterone Tylosin Tartrate
Implant Subcutaneous
Elanco US Inc. NADA 110-315 Approved Jul 3, 2024
Component™ TE-G Component™ TE-G with Tylan™ Component™ TE-S with Tylan™ Component™ TE-IS with Tylan™ Component™ TE-S Component™ TE-IS
RX
Estradiol Trenbolone Acetate Tylosin Tartrate
Implant Subcutaneous
Elanco US Inc. ANADA 200-221 Approved Jul 3, 2024
Paylean™ and Tylovet®
VFD
Ractopamine Hydrochloride Tylosin Phosphate
Type A medicated articles for use in the manufacture of Type B and Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-530 Approved Jul 25, 2023
Component™ TE-200 with Tylan™ Component™ TE-H with Tylan™ Component™ TE-IH with Tylan™
RX
Estradiol Trenbolone Acetate Tylosin Tartrate
Implant Subcutaneous
Elanco US Inc. ANADA 200-346 Approved Jul 3, 2023
Component® T-S with Tylan® Component® T-H with Tylan®
RX
Trenbolone Acetate Tylosin Tartrate
Implant (Pellet) Subcutaneous
Elanco US Inc. ANADA 200-224 Approved May 17, 2023
BiloVet®
RX
Tylosin Tartrate
Soluble Powder Oral
Bimeda Animal Health Limited ANADA 200-455 Approved Jan 3, 2023
BiloVet®
RX
Tylosin
Injection Intramuscular
Bimeda Animal Health Limited ANADA 200-508 Approved Dec 19, 2022
Tylovet® Soluble
RX
Tylosin Tartrate
Soluble Powder Oral
Huvepharma EOOD ANADA 200-473 Approved Jun 22, 2022
Tylovet® 40 Tylovet® 100
VFD
Tylosin Phosphate
Type A Medicated Article Oral
Huvepharma EOOD ANADA 200-484 Approved Jun 23, 2021
Rumensin™ and Tylan™
VFD
Monensin Tylosin Phosphate
Type A Medicated Article Oral
Elanco US Inc. NADA 104-646 Approved May 5, 2021
Monovet® and Tylan™
VFD
Monensin Tylosin
Type A medicated articles for use in the manufacture of Type B and Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-643 Approved Apr 23, 2021
Monovet® and Tylovet®
VFD
Monensin Tylosin
Type A medicated articles for use in the manufacture of Type B and Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-642 Approved Apr 23, 2021
CycleGuard® and Monovet® and Tylovet®
VFD
Melengestrol Acetate Monensin Tylosin
Type A medicated articles to be used in the manufacture of Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-685 Approved Mar 18, 2021
Optigrid® and Monovet® and Tylovet® and CycleGuard®
VFD
Melengestrol Acetate Monensin Ractopamine Hydrochloride Tylosin
Type A medicated articles to be used in the manufacture of Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-686 Approved Mar 18, 2021
Optigrid® and Monovet® and Tylovet®
VFD
Monensin Ractopamine Hydrochloride Tylosin Phosphate
Type A medicated articles for use in the manufacture of Type B and Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-676 Approved Feb 17, 2021
Optigrid® and Monovet® and Tylovet® and MGA®
VFD
Melengestrol Acetate Monensin Ractopamine Hydrochloride Tylosin
Type A medicated articles to be used in the manufacture of Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-678 Approved Feb 5, 2021
Tylan™ 5 Sulfa-G™ Tylan™ 10 Sulfa-G™ Tylan™ 20 Sulfa-G™ Tylan™ 40 Sulfa-G™
VFD
Sulfamethazine Tylosin Phosphate
Type A Medicated Article Oral
Elanco US Inc. NADA 41275 Approved Mar 18, 2020
MGA® and Monovet® and Tylan™
VFD
Melengestrol Acetate Monensin Tylosin Phosphate
Type A medicated articles to be used in the manufacture of Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-661 Approved Mar 16, 2020
MGA® and Monovet® and Tylovet®
VFD
Melengestrol Acetate Monensin Tylosin Phosphate
Type A medicated articles to be used in the manufacture of Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-660 Approved Mar 16, 2020
HeifermaX® 500 plus Bovatec® and Tylan™
VFD
Lasalocid Melengestrol Acetate Tylosin Phosphate
Medicated Feed Oral
Elanco US Inc. ANADA 200-430 Approved Mar 13, 2020
Actogain™ and Monovet® and Tylan™ and MGA®
VFD
Melengestrol Acetate Monensin Ractopamine Hydrochloride Tylosin
Type A medicated articles to be used in the manufacture of Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-651 Approved Feb 24, 2020
Actogain™ and Monovet® and Tylovet® and MGA®
VFD
Melengestrol Acetate Monensin Ractopamine Hydrochloride Tylosin
Type A medicated articles to be used in the manufacture of Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-649 Approved Feb 24, 2020
Deccox® and Monovet® and Tylan™
VFD
Decoquinate Monensin Tylosin Phosphate
Type A medicated articles for use in the manufacture of Type B and Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-656 Approved Feb 24, 2020
Deccox® and Monovet® and Tylovet®
VFD
Decoquinate Monensin Tylosin Phosphate
Type A medicated articles for use in the manufacture of Type B and Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-653 Approved Feb 24, 2020
Optaflexx™ and Monovet® and Tylan™ and MGA®
VFD
Melengestrol Acetate Monensin Ractopamine Hydrochloride Tylosin
Type A medicated articles to be used in the manufacture of Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-650 Approved Feb 24, 2020
Optaflexx™ and Monovet® and Tylovet® and MGA®
VFD
Melengestrol Acetate Monensin Ractopamine Hydrochloride Tylosin Phosphate
Type A medicated articles to be used in the manufacture of Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-648 Approved Feb 24, 2020
Actogain™ and Monovet® and Tylan™
VFD
Monensin Ractopamine Hydrochloride Tylosin
Type A medicated articles for use in the manufacture of Type B and Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-647 Approved Feb 21, 2020
Optaflexx™and Monovet® and Tylan™
VFD
Monensin Ractopamine Hydrochloride Tylosin Phosphate
Type A medicated articles for use in the manufacture of Type B and Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-646 Approved Feb 21, 2020
Actogain™ and Monovet® and Tylovet®
VFD
Monensin Ractopamine Hydrochloride Tylosin
Type A medicated articles for use in the manufacture of Type B and Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-645 Approved Feb 19, 2020
Optaflexx™and Monovet® and Tylovet®
VFD
Monensin Ractopamine Hydrochloride Tylosin
Type A medicated articles for use in the manufacture of Type B and Type C medicated feeds Oral
Huvepharma EOOD ANADA 200-644 Approved Feb 19, 2020
Tylan Soluble™
RX
Tylosin Tartrate
Soluble Powder Oral
Elanco US Inc. NADA 13076 Approved Dec 30, 2019
Tylan 5, 10, 20 40 Premix
OTC
Tylosin Phosphate
Type A Medicated Article Oral
Stutts Scientific Service, Inc. NADA 139-488 W Aug 8, 2019
M & M Tylosin Premix
OTC
Tylosin Phosphate
Medicated Feed Oral
M & M Livestock Products Co. NADA 96837 W Apr 26, 2019
Tylan® plus Sacox®
OTC
Salinomycin Sodium Tylosin Phosphate
Type A Medicated Article Oral
Huvepharma EOOD ANADA 200-569 W Mar 17, 2019
Tylovet®100 plus Bio-cox®
OTC
Salinomycin Sodium Tylosin Phosphate
Type A Medicated Article Oral
Huvepharma EOOD ANADA 200-570 W Mar 17, 2019
Tylan™ and Banminth®
VFD
Pyrantel Tartrate Tylosin Phosphate
Type A Medicated Article Oral
Phibro Animal Health Corp. NADA 110-047 Approved Dec 2, 2018
Heifermax™ 500 Liquid Premix and Tylan®
VFD
Melengestrol Acetate Tylosin Phosphate
Medicated Feed Oral
Elanco US Inc. ANADA 200-427 Approved Nov 13, 2018
MGA®/ Bovatec®/ Tylovet® 100
VFD
Lasalocid Melengestrol Acetate Tylosin Phosphate
Medicated Feed Oral
Huvepharma EOOD ANADA 200-535 Approved Nov 8, 2018
MGA® plus Tylovet® 100
VFD
Melengestrol Acetate Tylosin Phosphate
Type A Medicated Article Oral
Huvepharma EOOD ANADA 200-532 Approved Nov 8, 2018
Zilmax® and Rumensin™ and Tylan™
VFD
Monensin Tylosin Phosphate Zilpaterol Hydrochloride
Type A Medicated Article Oral
Intervet, Inc. NADA 141-276 Approved Oct 25, 2018
Optaflexx™ and Rumensin™ and Tylan™
VFD
Monensin Ractopamine Hydrochloride Tylosin Phosphate
Type A Medicated Article Oral
Elanco US Inc. NADA 141-224 Approved Oct 18, 2018
Optaflexx™ and Rumensin™ and Tylan™and MGA®
VFD
Melengestrol Acetate Monensin Ractopamine Hydrochloride Tylosin Phosphate
Type A Medicated Article Oral
Elanco US Inc. NADA 141-233 Approved Oct 17, 2018
Tylovet® 100 plus Sacox®
OTC
Salinomycin Sodium Tylosin Phosphate
Type A Medicated Article Oral
Huvepharma EOOD ANADA 200-580 W Mar 2, 2018
Bovatec® / MGA® 100 / Tylan® Bovatec® / MGA® 100-200 Premix / Tylan® Bovatec® / MGA® 500 Liquid Premix / Tylan® Bovatec® / MGA® 200 / Tylan®
OTC
Lasalocid Melengestrol Acetate Tylosin Phosphate
Medicated Feed Oral
Zoetis Inc. NADA 138-904 W Dec 7, 2017
TYLAN™ 20 TYLAN™ 40
VFD
Tylosin Phosphate
Type A Medicated Article Oral
Phibro Animal Health Corp. NADA 98431 Approved Jan 3, 2017
Alley Tylan®-10 Premix
OTC
Tylosin Phosphate
Dale Alley Co. NADA 96512 W Jun 1, 2016
Coban® / Tylan®
OTC
Monensin Tylosin Phosphate
Medicated Feed Oral
Elanco US, Inc. NADA 141-164 W Jun 1, 2016
CO-OP Tylan® 10 Premix Medicated
OTC
Tylosin Phosphate
Indiana Farm Bureau Coop. Assn. NADA 125-226 W Jun 1, 2016
Fasco Super Tylosin Premix
OTC
Tylosin Phosphate
Fasco Mills Co. NADA 96839 W Jun 1, 2016
Formica Premix-T Medicated
OTC
Tylosin
Mountaire Feeds, Inc. NADA 44013 W Jun 1, 2016
FS Tylan® 40 Mix Med.
OTC
Tylosin Phosphate
Growmark, Inc. NADA 99098 W Jun 1, 2016
Gilt Edge Tylan® Mix
OTC
Tylosin Phosphate
Medicated Feed Oral
ADM Alliance Nutrition, Inc. NADA 91582 W Jun 1, 2016
Good-Life Tylan® 10 Premix
OTC
Tylosin Phosphate
Medicated Feed Oral
ADM Alliance Nutrition, Inc. NADA 110-045 W Jun 1, 2016
Gossett G-F Swine Premixes Baby Pig Premix
OTC
Tylosin Phosphate
Medicated Feed Oral
Gossett Nutrition, Inc. NADA 131-537 W Jun 1, 2016
Heinold Tylan® 5 Sulfa Premix Tylan® 10 Sulfa-G Tylan® 5 Sulfa-G Tylan® 40 Sulfa-G Tylan® 20 Sulfa-G
OTC
Sulfamethazine Tylosin Phosphate
Heinold Feeds, Inc. NADA 127-506 W Jun 1, 2016
HFA Tylosin-10 Plus Sulfa
OTC
Sulfamethazine Tylosin Phosphate
Medicated Feed Oral
ADM Alliance Nutrition, Inc. NADA 108-484 W Jun 1, 2016
Hog-Grow-R-Mix-800 Hog Grow-R-Mix-4000
OTC
Tylosin Phosphate
Youngs, Inc. NADA 96162 W Jun 1, 2016
Hubbard Tylan® Plus Sulfa Premix
OTC
Sulfamethazine Tylosin Phosphate
Hubbard Milling Co. NADA 94402 W Jun 1, 2016
Hy-Con Tylan® Premix
OTC
Tylosin Phosphate
Medicated Feed Oral
Yoder Feed NADA 96161 W Jun 1, 2016
Hygromix-Tylan® Premix
OTC
Hygromycin B Tylosin
Medicated Feed Oral
Elanco US, Inc. NADA 13388 W Jun 1, 2016
Hy-Test Hy-Boost TY 5 Medicated
OTC
Tylosin Phosphate
Medicated Feed Oral
Kerber Milling Co. NADA 98687 W Jun 1, 2016
Ingmands Swine Premix-T Medicated
OTC
Tylosin
The Eugene Ingmand Co. NADA 91465 W Jun 1, 2016
Kay Dee Tylan® 10 Premix-Med
OTC
Tylosin Phosphate
Kay Dee Feed Co. NADA 111-814 W Jun 1, 2016
McNess Custom Premix L200
OTC
Tylosin Phosphate
Medicated Feed Oral
Furst-McNess Co. NADA 100-991 W Jun 1, 2016
Mill Co Medicator TS-40 Premix
OTC
Sulfamethazine Tylosin Phosphate
Medicated Feed Oral
Waterloo Mills Co. NADA 101-906 W Jun 1, 2016
Mill Co-Medicator TY-4 Mill Co-Medicator TY-10
OTC
Tylosin Phosphate
Medicated Feed Oral
Waterloo Mills Co. NADA 101-905 W Jun 1, 2016
Monteban® / Tylan®
OTC
Narasin Tylosin Phosphate
Medicated Feed Oral
Elanco US, Inc. NADA 141-170 W Jun 1, 2016
Moormaboost TY 4000 Medicated
OTC
Tylosin Phosphate
Medicated Feed Oral
ADM Alliance Nutrition, Inc. NADA 95953 W Jun 1, 2016
Norco T-2 Pre-Pak
OTC
Tylosin Phosphate
Medicated Feed Oral
Norco Mills Of Norfolk, Inc. NADA 49890 W Jun 1, 2016
NSI Tylosin 10 Premix
OTC
Tylosin
Neese & Sons, Inc. NADA 102-717 W Jun 1, 2016
Nutra-Blend Tylan® 10 Premix
OTC
Tylosin Phosphate
Nutra-Blend Corp. NADA 122-158 W Jun 1, 2016
Nutra-Blend Tylan® 5 Sulfa Premix Tylan® 10 Sulfa Premix Tylan® 5 Sulfa Premix Tylan® 40 Sulfa Premix Tylan® 20 Sulfa Premix
OTC
Sulfamethazine Tylosin Phosphate
Medicated Feed Oral
Nutra-Blend Corp. NADA 129-161 W Jun 1, 2016
Pioneer Hog Care Premix
OTC
Tylosin Phosphate
Triple "F", Inc. NADA 91783 W Jun 1, 2016
Pro Mix T Medicated Medi-Flex T Tylan® Premix
OTC
Tylosin Phosphate
Land OLakes Purina Feed LLC NADA 42489 W Jun 1, 2016
Purina® Hog Plus II
OTC
Tylosin Phosphate
Medicated Feed Oral
Virbac AH, Inc. NADA 43387 W Jun 1, 2016
Purina® Pork-Plus Medicated
OTC
Sulfamethazine Tylosin Phosphate
Medicated Feed Oral
Virbac AH, Inc. NADA 42660 W Jun 1, 2016
Purina® Tylan® 40 Plus Sulfamethazine
OTC
Sulfamethazine Tylosin Phosphate
Medicated Feed Oral
Virbac AH, Inc. NADA 99767 W Jun 1, 2016
Quali-Tech Tylan®-10 Premix
OTC
Tylosin Phosphate
Medicated Feed Oral
Quali-Tech Products, Inc. NADA 97980 W Jun 1, 2016
Rx-Link-Tylan® 1600
OTC
Tylosin Phosphate
United Suppliers, Inc. NADA 102-590 W Jun 1, 2016
Seeco Inc T-10 Premix
OTC
Tylosin Phosphate
Medicated Feed Oral
Truow Nutrition, Inc. NADA 100-352 W Jun 1, 2016
Seeco Tylan®-Sulfa 10 Premix Med.
OTC
Sulfamethazine Tylosin Phosphate
Medicated Feed Oral
Truow Nutrition, Inc. NADA 107-002 W Jun 1, 2016
Simonsen Tylan® Vitamin Premix
OTC
Tylosin Phosphate
Simonsen Mill-Rendering Plant, Inc. NADA 96776 W Jun 1, 2016
Supersweet Medipak Tylan® 10
OTC
Tylosin Phosphate
Medicated Feed Oral
Cross Vetpharm Group Ltd. NADA 100-128 W Jun 1, 2016
Swine Med-A-Mix TS 8000 Premix Tylan® 10 Sulfa-G Tylan® 5 Sulfa-G Tylan® 40 Sulfa-G Tylan® 20 Sulfa-G
OTC
Sulfamethazine Tylosin Phosphate
Golden Sun Feeds, Inc. NADA 97615 W Jun 1, 2016
Swine Premix 18586 Broiler Premix 18586
OTC
Tylosin Phosphate
Roche Vitamins, Inc. NADA 42755 W Jun 1, 2016
Thrifty Swine Mix
OTC
Tylosin Phosphate
Old Monroe Elevator & Supply Co., Inc. NADA 119-261 W Jun 1, 2016
Tylan® 10
OTC
Tylosin Phosphate
Medicated Feed
Feed Specialties Co., Inc. NADA 97289 W Jun 1, 2016
Tylan® 100 Premix
OTC
Tylosin Phosphate
Medicated Feed Oral
Elanco US, Inc. NADA 15166 W Jun 1, 2016
Tylan® 10 Plus
OTC
Tylosin Phosphate
Bioproducts, Inc. NADA 93518 W Jun 1, 2016
Tylan® 10 Premix
OTC
Tylosin Phosphate
Golden Sun Feeds, Inc. NADA 97567 W Jun 1, 2016
Tylan® 10 Premix
OTC
Tylosin Phosphate
ADM Alliance Nutrition, Inc. NADA 107-958 W Jun 1, 2016
Tylan® 10 Premix
OTC
Tylosin Phosphate
Medicated Feed Oral
Truow Nutrition, Inc. NADA 133-833 W Jun 1, 2016
Tylan® 10 Premix Tylan® 100 Premix Tylan® 40 Premix
OTC
Tylosin Phosphate
Medicated Feed Oral
Micro Beef Technologies, Inc. NADA 138-187 W Jun 1, 2016
Tylan® 10 Premix Tylan® 20 Premix Tylan® 5 Premix Tylan® 40 Premix
OTC
Tylosin Phosphate
Medicated Feed Oral
Pharmgate LLC NADA 140-680 W Jun 1, 2016
Tylan 10 Premix Tylan 5 Premix Tylan 40 Premix Tylan 20 Premix
OTC
Tylosin
Agri-Basics NADA 140-531 W Jun 1, 2016
Tylan® 10 Sulfa-G Premix Tylan® 5 Sulfa-G Premix Tylan® 40 Sulfa-G Premix Tylan® 20 Sulfa-G Premix
OTC
Sulfamethazine Tylosin Phosphate
Southern Micro-Blenders, Inc. NADA 138-453 W Jun 1, 2016
Tylan® 10 Sulfa-G Premix Tylan® 5 Sulfa-G Premix Tylan® 40 Sulfa-G Premix Tylan® 20 Sulfa-G Premix
OTC
Sulfamethazine Tylosin Phosphate
Oral
J & R Specialty Supply Co. NADA 138-454 W Jun 1, 2016
Tylan® 10 Sulfa-G Premix Tylan® 5 Sulfa-G Premix Tylan® 40 Sulfa-G Premix Tylan® 20 Sulfa-G Premix
OTC
Sulfamethazine Tylosin Phosphate
Walnut Grove Products NADA 139-301 W Jun 1, 2016
Tylan® 10 Sulfa-G Premix Tylan® 5 Sulfa-G Premix Tylan® 40 Sulfa-G Premix Tylan® 20 Sulfa-G Premix
OTC
Sulfamethazine Tylosin Phosphate
Arkansas Micro Specialties, Inc. NADA 139-601 W Jun 1, 2016
Tylan® 10 Sulfa-G Premix Tylan® 5 Sulfa-G Premix Tylan® 40 Sulfa-G Premix Tylan® 20 Sulfa-G Premix
OTC
Sulfamethazine Tylosin Phosphate
Medicated Feed Oral
Furst-McNess Co. NADA 140-820 W Jun 1, 2016
Tylan® 10 Sulfa-G Tylan® 20 Sulfa-G Quali-Tech Tylan®-Sulfa Premix 10 -10 Tylan® 5 Sulfa-G Tylan® 40 Sulfa-G
OTC
Sulfamethazine Tylosin Phosphate
Medicated Feed Oral
Quali-Tech Products, Inc. NADA 97981 W Jun 1, 2016
Tylan® 10 Sulfa-G Tylan® 40 Sulfa-G Tylan® 5 Sulfa-G Tylan® 20 Sulfa-G
OTC
Sulfamethazine Tylosin Phosphate
Medicated Feed Oral
ADM Alliance Nutrition, Inc. NADA 111-069 W Jun 1, 2016
Tylan 10 Sulfa-G Tylan 5 Sulfa-G Tylan 40 Sulfa-G Tylan 20 Sulfa-G
OTC
Sulfamethazine Tylosin
Medicated Feed
Agri-Basics NADA 140-530 W Jun 1, 2016
Tylan® 10 Sulfa-G Tylan® 5 Sulfa-G Tylan® 40 Sulfa-G Tylan® 20 Sulfa-G
OTC
Sulfamethazine Tylosin Phosphate
Medicated Feed Oral
International Nutrition, Inc. NADA 109-816 W Jun 1, 2016
Tylan® 10 Sulfa-G Tylan® 5 Sulfa-G Tylan® 40 Sulfa-G Tylan® 20 Sulfa-G
OTC
Sulfamethazine Tylosin Phosphate
Old Monroe Elevator & Supply Co., Inc. NADA 128-835 W Jun 1, 2016
Tylan® 10 Sulfa-G Tylan® 5 Sulfa-G Tylan® 40 Sulfa-G Tylan® 20 Sulfa-G
OTC
Sulfamethazine Tylosin Phosphate
Medicated Feed Oral
Custom Feed Services Corp. NADA 129-159 W Jun 1, 2016
Tylan® 10 Sulfa-G Tylan® 5 Sulfa-G Tylan® 40 Sulfa-G Tylan® 20 Sulfa-G
OTC
Sulfamethazine Tylosin Phosphate
Growmark, Inc. NADA 130-465 W Jun 1, 2016
Tylan® 10 Tylan® 5 Tylan® 40 Tylan® 20
OTC
Tylosin Phosphate
Hubbard Milling Co. NADA 48645 W Jun 1, 2016
Tylan® 10 Tylan® 5 Tylan® 40 Tylan® 20
OTC
Tylosin Phosphate
Medicated Feed Oral
Provimi North America, Inc. NADA 103-089 W Jun 1, 2016
Tylan® 10 Tylan® 5 Tylan® 40 Tylan® 20
OTC
Tylosin Phosphate
Medicated Feed Oral
ADM Alliance Nutrition, Inc. NADA 131-957 W Jun 1, 2016
Tylan® 10 Tylan® 5 Tylan® 40 Tylan® 20
OTC
Tylosin Phosphate
Ohio Farmers Grain and Supply Association NADA 137-051 W Jun 1, 2016
Tylan® 10 Tylan® 5 Tylan® 40 Tylan® 20
OTC
Tylosin Phosphate
Arkansas Micro Specialties, Inc. NADA 139-600 W Jun 1, 2016
Tylan® 20 Sulfa-G Premix Tylan® 10 Sulfa-G Premix Tylan® 5 Sulfa-G Premix Tylan® 40 Sulfa-G Premix
OTC
Sulfamethazine Tylosin Phosphate
Medicated Feed Oral
Pharmgate LLC NADA 140-681 W Jun 1, 2016
Tylan® 20 Sulfa-G Tylan® 40 Sulfa-G Tylan® 5 Sulfa-G Tylan® 10 Sulfa-G Tylan® 5 Sulfa Premix
OTC
Sulfamethazine Tylosin Phosphate
Medicated Feed Oral
I.M.S., Inc. NADA 129-646 W Jun 1, 2016
Tylan® 40 Sulfa-G Premix Tylan® 5 Sulfa-G Premix Tylan® 20 Sulfa-G Premix Tylan® 10 Sulfa-G Premix
OTC
Sulfamethazine Tylosin Phosphate
Medicated Feed Oral
Feed Service Co., Inc. NADA 138-342 W Jun 1, 2016
Tylan® 40 Sulfa-G Tylan® 20 Sulfa-G
OTC
Sulfamethazine Tylosin Phosphate
Medicated Feed Oral
ADM Alliance Nutrition, Inc. NADA 107-957 W Jun 1, 2016
Tylan® 40 Sulfa-G Tylan® 5 Sulfa-G Tylan® 20 Sulfa-G Tylan® 10 Sulfa-G
OTC
Sulfamethazine Tylosin Phosphate
Medicated Feed Oral
Elanco US, Inc. NADA 127-507 W Jun 1, 2016
Tylan® 40 Tylan® 10
OTC
Tylosin Phosphate
Medicated Feed Oral
J & R Specialty Supply Co. NADA 96780 W Jun 1, 2016
Tylan® 5 Premix
OTC
Tylosin Phosphate
Medicated Feed Oral
International Nutrition, Inc. NADA 95551 W Jun 1, 2016
Tylan® 5 Sulfa Premix
OTC
Sulfamethazine Tylosin Phosphate
Medicated Feed Oral
ADM Alliance Nutrition, Inc. NADA 128-411 W Jun 1, 2016
Tylan® 5 Sulfa Premix Tylan® 10 Sulfa Premix
OTC
Sulfamethazine Tylosin Phosphate
Kay Dee Feed Co. NADA 128-255 W Jun 1, 2016
Tylan® / Bio-Cox®
OTC
Salinomycin Sodium Tylosin Phosphate
Medicated Feed Oral
Elanco US, Inc. NADA 141-198 W Jun 1, 2016
Tylan® Injectable
OTC
Tylosin Tartrate
Elanco Animal Health, A Division of Eli Lilly & Co. NADA 12585 W Jun 1, 2016
Tylan® Plus Neomycin Eye Powder
OTC
Neomycin Sulfate Tylosin
Elanco Animal Health, A Division of Eli Lilly & Co. NADA 31962 W Jun 1, 2016
Tylan® Plus Vitamins
OTC
Folic Acid Pyridoxine Hydrochloride Tylosin Vitamin A Vitamin B1 Vitamin B2 Vitamin B5 Vitamin D Vitamin E
Elanco Animal Health, A Division of Eli Lilly & Co. NADA 13029 W Jun 1, 2016
Tylan® Premix No.10
OTC
Tylosin Phosphate
Medicated Feed Oral
Elanco US, Inc. NADA 13162 W Jun 1, 2016
Tylan® Sulfa
OTC
Sulfamethazine Tylosin Phosphate
Oral
ADM Alliance Nutrition, Inc. NADA 127-826 W Jun 1, 2016
Tylan® Sulfa 10-10 Premix Medi-Flex T:S
OTC
Sulfamethazine Tylosin Phosphate
Land OLakes Purina Feed LLC NADA 98156 W Jun 1, 2016
Tylan® Sulfa 10 G Tylan® Sulfa 5 G Tylan® Sulfa 40 G Tylan® Sulfa 20 G
OTC
Sulfamethazine Tylosin Phosphate
Triple "F", Inc. NADA 99561 W Jun 1, 2016
Tylan® Sulfa-G
OTC
Sulfamethazine Tylosin
Medicated Feed Oral
ADM Alliance Nutrition, Inc. NADA 131-956 W Jun 1, 2016
Tylan® Sulfa-G
OTC
Sulfamethazine Tylosin Phosphate
Medicated Feed Oral
Wayne Feed Division, Continental Grain Co. NADA 131-958 W Jun 1, 2016
Tylan® Sulfa-G
OTC
Sulfamethazine Tylosin Phosphate
Ohio Farmers Grain and Supply Association NADA 138-343 W Jun 1, 2016
Tylocine Sulfa Tablets 50
RX
Sulfadiazine Sulfamerazine Sulfamethazine Tylosin
Elanco Animal Health, A Division of Eli Lilly & Co. NADA 30330 W Jun 1, 2016
Tylosin® 10 Premix
OTC
Tylosin Phosphate
Medicated Feed Oral
Custom Feed Services Corp. NADA 121-200 W Jun 1, 2016
Tylosin® 10 Type A Medicated Article Tylosin® 5 Type A Medicated Article Tylosin® 40 Type A Medicated Article Tylosin® 20 Type A Medicated Article
OTC
Tylosin Phosphate
Alpharma, LLC, a wholly owned subsidiary of Pfizer, Inc. NADA 111-637 W Jun 1, 2016
Tylosin® Antibiotic Premix
OTC
Tylosin Phosphate
Heinold Feeds, Inc. NADA 95628 W Jun 1, 2016
Tylosin® / Hygromix
OTC
Hygromycin B Tylosin Phosphate
Medicated Feed Oral
Elanco US, Inc. NADA 12548 W Jun 1, 2016
Tylosin® Premix 4
OTC
Tylosin Phosphate
Henwood Feed Additives NADA 45690 W Jun 1, 2016
Tyson Tylan® Premix 1 Medicated Tyson Tylan® Premix 5 Medicated Tyson Tylan® Premix 2 Medicated
OTC
Tylosin Phosphate
Tyson Food, Inc. NADA 121-290 W Jun 1, 2016
Vigorena Feeds Hy-Ty Premix
OTC
Tylosin Phosphate
Medicated Feed Oral
Springfield Milling Corp. NADA 100-556 W Jun 1, 2016
Vita Plus N-Richer Pig Grower
OTC
Tylosin Phosphate
Vita Plus Corp. NADA 97287 W Jun 1, 2016
V.P.O. Tylan® Plus Sulfa
OTC
Sulfamethazine Tylosin
SmithKline Beecham Animal Health NADA 100-127 W Jun 1, 2016
Walnut Grove 4x4 Add-Mix T
OTC
Tylosin Phosphate
Cargill, Inc., Nutrena Feed Division NADA 98595 W Jun 1, 2016
Waynextra For Swine
OTC
Tylosin Phosphate
Medicated Feed Oral
Wayne Feed Division, Continental Grain Co. NADA 99468 W Jun 1, 2016
Webel Tylan® Premix
OTC
Tylosin Phosphate
Webel Feeds, Inc. NADA 116-196 W Jun 1, 2016

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Finishing
Composition / specifications
Type A medicated articles containing ractopamine hydrochloride (9 or 45.4 g/lb) and tylosin phosphate (10, 40, or 100 g/lb).
Swine
Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, control of swine dysentery associated with Brachyspira hyodysenteriae, and control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis in finishing swine weighing at least 150 lbs and fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter. No increased benefit has been shown when ractopamine concentrations in the diet are greater than 4.5 g/ton.

Dosage

4.5 to 9.0 g ractopamine hydrochloride and 40 to 100 g tylosin (as tylosin phosphate) per ton of Type C medicated feed.

Limitations

Feed continuously as the sole ration to finishing swine weighing at least 150 lbs for the last 45 to 90 lbs (group average) of weight gain prior to slaughter. Include 100 g/ton of tylosin for at least 3 weeks, followed by 40 g/ton until market weight. Ractopamine hydrochloride may increase the number of injured and/or fatigued pigs during marketing. Not for animals intended for breeding. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite

Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, and control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis in finishing swine weighing at least 150 lbs and fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter. No increased benefit has been shown when ractopamine hydrochloride concentrations in the diet are greater than 4.5 g/ton (5 ppm).

Dosage

4.5 to 9.0 g ractopamine hydrochloride and 100 g tylosin (as tylosin phosphate) per ton of Type C medicated feed.

Limitations

Feed continuously as the sole ration to finishing swine weighing at least 150 lbs for the last 45 to 90 lbs (group average) of weight gain prior to slaughter. Include 100 g/ton of tylosin for 21 days. Ractopamine hydrochloride may increase the number of injured and/or fatigued pigs during marketing. Not for animals intended for breeding. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite.

Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, the treatment and control of swine dysentery associated with Brachyspira hyodysenteriae, and control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis in finishing swine weighing at least 150 lbs and fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter. No increased benefit has been shown when ractopamine hydrochloride concentrations in the diet are greater than 4.5 g/ton (5 ppm).

Dosage

4.5 to 9.0 g ractopamine hydrochloride and 40 to 100 g tylosin (as tylosin phosphate) per ton of Type C medicated feed.

Limitations

Feed continuously as the sole ration to finishing swine weighing at least 150 lbs for the last 45 to 90 lbs (group average) of weight gain prior to slaughter. Feed 40 to 100 grams of tylosin per ton of complete feed for 2 to 6 weeks immediately after medicating with 250 mg tylosin tartrate (Tylan Soluble) per gallon in drinking water for 3 to 10 days. Ractopamine hydrochloride may increase the number of injured and/or fatigued pigs during marketing. Not for animals intended for breeding. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite.

FDA page: Open in Animal Drugs @ FDA

Species: Fed in confinement for slaughter
Composition / specifications
<p class="GBKentryleft">Ractopamine hydrochloride &ndash; 45.4 g/lb</p>
<p class="GBKentryleft">Monensin USP &ndash; 90.7 g/lb</p>
<p class="GBKentryleft">Tylosin phosphate &ndash; 40 and 100 g/lb
Cattle
Indication

For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

Ractopamine hydrochloride (8.2 to 24.6 g/ton) in combination with monensin sodium (10 to 40 g/ton) and tylosin phosphate (8 to 10 g/ton)

Limitations

Feed continuously as sole ration for the last 28 to 42 days on ration. Ractopamine HCl is not for animals intended for breeding. Do not use in calves to be processed for veal.

Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Indication
For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.
Dosage

Ractopamine hydrochloride (9.8 to 24.6 g/ton) in combination with monensin sodium (10 to 40 g/ton) and tylosin phosphate (8 to 10 g/ton).

Limitations

Feed continuously as sole ration for the last 28 to 42 days on ration. Ractopamine HCl is not for animals intended for breeding. Do not use in calves to be processed for veal.

Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Indication
For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction in incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter during the last 28 to 42 days on feed
Dosage

Ractopamine hydrochloride top dress (not to exceed 800 g/ton) plus monensin sodium (10 to 40 g/ton) in combination with tylosin phosphate (8 to 10 g/ton).

Limitations

Feed continuously as sole ration for the last 28 to 42 days on ration. Ractopamine HCl is not for animals intended for breeding. Do not use in calves to be processed for veal. 

Liquid Type B Medicated Feeds must bear the following caution: 

Inadequate mixing (recirculation or agitation) of monensin liquid Type B medicated feed has resulted in increased monensin concentration, which has been fatal to cattle. Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Feeding undiluted or mixing errors resulting in high concentrations of monensin has been fatal to cattle. Must be thoroughly mixed in feeds before use. Do not feed undiluted. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing.

Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Beef heifers fed in confinement for slaughter
Composition / specifications
Ractopamine hydrochloride &ndash; 45.4 g/lb</p>
<p>Monensin USP &ndash; 90.7 g/lb</p>
<p>Tylosin phosphate &ndash; 40 and 100 g/lb</p>
<p>Melengestrol acetate &ndash; 200 and 500 mg/lb
Cattle, Beef heifers fed in confinement for slaughter
Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes and suppression of estrus (heat) in heifers fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

Ractopamine is fed at concentrations of 9.8 to 24.6 g of ractopamine hydrochloride per ton of complete feed (based on 90% dry matter basis) to provide 90 to 430 mg ractopamine/head/day in cattle fed in confinement for slaughter during the last 28 to 42 days on feed. Monensin is added to feedlot cattle diets at concentrations of 10 to 40 g of monensin USP per ton of complete feed at a rate of 0.14 to 0.42 mg monensin/lb of body weight, depending on severity of coccidiosis challenge, up to 480 mg/head/day. Tylosin is added to the cattle diets at concentrations of 8 to 10 g of tylosin phosphate per ton of complete feed to provide 60 to 90 mg tylosin/head/day. Melengestrol acetate is added to the diet of heifers at 0.5 to 2.0 pounds per head per day of medicated feed containing 0.125 to 1.0 mg melengestrol acetate per pound to provide 0.25 to 0.5 mg melengestrol acetate/head/day in heifers being fed for slaughter.

Limitations

Feed continuously as sole ration during the last 28 to 42 days on feed. Not for animals intended for breeding. Do not use in calves to be processed for veal.Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Beef fed In confinement for slaughter
Composition / specifications
Ractopamine hydrochloride - 45.4 g/lb</p>
<p>Monensin USP - 90.7 g/lb</p>
<p>Tylosin phosphate - 100 g/lb
Cattle, Beef fed in confinement for slaughter
Indication

For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to E. bovis and E. zuernii and reduction in incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter during the last 28 to 42 days on feed.

Dosage

Ractopamine hydrochloride top dress (not to exceed 800 g/ton) to be fed with a ration containing 10 to 40 g/ton monensin in combination with 8 to 10 g/ton tylosin phosphate.

Limitations

Feed continuously as sole ration during the last 28 to 42 days on feed. Do not use in calves to be processed for veal. Ractopamine HCl is not for animals intended for breeding. Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Indication
For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.
Dosage
Ractopamine hydrochloride (8.2 to 24.6 g/ton) in combination with monensin USP (10 to 40 g/ton) and tylosin phosphate (8 to 10 g/ton).
Limitations

Feed continuously as sole ration during the last 28 to 42 days on feed. Do not use in calves to be processed for veal. Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Ractopamine HCl is not for animals intended for breeding. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Indication
For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to E. bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.
Dosage

Ractopamine hydrochloride (9.8 to 24.6 g/ton) in combination with monensin USP (10 to 40 g/ton) and tylosin phosphate (8 to 10 g/ton).

Limitations

Feed continuously as sole ration during the last 28 to 42 days on feed. Do not use in calves to be processed for veal. Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Ractopamine HCl is not for animals intended for breeding. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Beef heifers fed in confinement for slaughter
Composition / specifications
Ractopamine hydrochloride - 45.4 g/lb</p>
<p>Monensin USP - 90.7 g/lb</p>
<p>Tylosin phosphate - 100 g/lb</p>
<p>Melengestrol acetate - 200 (dry) and 500 (liquid) mg/lb
Label highlights
Indication
For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes and suppression of estrus (heat) in heifers fed in confinement for slaughter for the last 28 to 42 days on feed
Dosage
Ractopamine is fed at a concentration of 9.8 to 24.6 g of ractopamine per ton of complete feed (based on 90% dry matter basis) to provide 90-430 mg ractopamine/head/day in cattle fed in confinement for slaughter during the last 28 to 42 days on feed.

Monensin is added to feedlot cattle diets at concentrations of 10 to 40 g monensin USP per ton of complete feed to provide 0.14 to 0.42 mg monensin/lb of body weight/day, depending on severity of coccidiosis challenge, up to a maximum of 480 mg monensin/head/day.

Tylosin is added to the cattle diets at concentrations of 8 to 10 g tylosin phosphate per ton complete feed to provide 60 to 90 mg tylosin/head/day.

Melengestrol acetate is added to the diet of heifers at 0.5 to 2.0 pounds per head per day of medicated feed containing 0.125 to 1.0 mg melengestrol acetate per pound to provide 0.25 to 0.5 mg melengestrol acetate per head per day in heifers fed in confinement for slaughter. Feed melengestrol acetate in this combination for the final 28 to 42 days.

Limitations

Feed continuously as sole ration during the last 28 to 42 days on feed. Melengestrol acetate is not effective in steers and spayed heifers. Withdrawal periods of three to five days should be avoided to prevent the possibility that the heifers may come into estrus (heat) at time of loading. Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Ractopamine HCl is not for animals intended for breeding. Do not use in calves to be processed for veal. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Special considerations: Mixing directions for liquid melengestrol acetate Type C feeds stored in recirculation tank systems, labeling indicates: “Recirculate immediately prior to use for no less than 10 minutes, moving not less than 1 percent of the tank contents from the bottom of the tank to the top. Recirculate daily, as directed in this paragraph even when the Type C feed is not used.” For liquid melengestrol Type C feeds stored in mechanical, air or other agitation-type tank systems: “Agitate immediately prior to use for not less than 10 minutes, creating turbulence at the bottom of the tank that is visible at the top. Agitate daily, as directed in this paragraph, even when the Type C feed is not used.”

FDA page: Open in Animal Drugs @ FDA

Species: Growing-Finishing Cattle Being Fed In Confinement For Slaughter
Composition / specifications
Decoquinate 27.2 g/lb; Monensin USP 20, 30, 45, 60, 80, and 90.7 g/lb;Tylosin phosphate 40 and 100 g/lb
Cattle (Growing finishing cattle being fed in confinement for slaughter)
Indication

For the prevention of coccidiosis caused by Eimeria bovis and E. zuernii, for improved feed efficiency, and for reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in cattle fed in confinement for slaughter.

Dosage

13.6 to 27.2 grams decoquinate per ton and 5 to 30 grams monensin per ton and 8 to 10 grams tylosin per ton.

Limitations

Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.Feed only to cattle fed in confinement for slaughter. Feed continuously as the sole ration to provide 22.7 mg of decoquinate per 100 lb body weight per day, 50 to 360 mg of monensin per head per day, and 60 to 90 mg of tylosin per head per day. Feed at least 28 days during period of exposure to coccidiosis or when it is likely to be a hazard. Bentonite should not be used in decoquinate feeds. Do not allow horses or other equines access to formulations containing monensin. Ingestion of monensin by equines has been fatal. Monensin medicated cattle and goat feeds are safe for use in cattle and goats only. Consumption by unapproved species may result in toxic reactions. Feeding undiluted or mixing errors resulting in high concentrations of monensin has been fatal to cattle and could be fatal to goats. Must be thoroughly mixed in feeds before use. Do not feed undiluted. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing.

FDA page: Open in Animal Drugs @ FDA

Species: Beef heifers fed in confinement for slaughter
Composition / specifications
Melengestrol acetate: 500 g/lb; Monensin: 80 g/lb; Tylosin phosphate: 40 and 100 g/lb
Cattle (heifers fed in confinement for slaughter)
Indication

Increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium pyogenes in heifers fed in confinement for slaughter.

Dosage

Melengestrol acetate (0.25 to 2 g/ton) in combination with monensin (10 to 40 g/ton) and tylosin (8 to 10 g/ton).

Limitations

Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Feed continuously as sole ration to heifers at a rate of 0.5 to 2.0 pounds per head per day to provide 0.25 to 0.5 mg/head/day melengestrol acetate and 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/head/day and 60 to 90 mg/head/day tylosin. The melengestrol acetate portion of this Type C medicated feed must be mixed into the complete feed containing 10 to 40 g/ton monensin and 8 to 10 g/ton tylosin at feeding into the amount of complete feed consumed by an animal per day. 

Melengestrol acetate is for use only in heifers being fed in confinement for slaughter. Not effective in steers or spayed heifers. Heifers fed in confinement for slaughter: Withdrawal periods of three to five days should be avoided to prevent the possibility that the heifers may come into estrus (heat) at the time of loading.

Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle and goat feed is safe for use in cattle and goats only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing.

Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite.

FDA page: Open in Animal Drugs @ FDA

Species: Cattle, Heifers Fed In Confinement For Slaughter
Composition / specifications
Type A medicated articles containing melengestrol acetate (500 mg/lb), zilpaterol hydrochloride (21.77 g/lb), tylosin phosphate (40 and 100 g/lb), and monensin USP (80 g/lb).
Cattle (Heifer)
Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes and suppression of estrus (heat) in heifers fed in confinement for slaughter for the last 20 to 40 days on feed.

Dosage

Melengestrol acetate (0.125 to 1. 0 mg/lb is top dressed or mixed with a complete ration containing monensin (10 to 40 g/ton), tylosin (8 to 10 g/ton), and zilpaterol (6.8 g/ton).

Limitations

Feed continuously as the sole ration for the final 20 to 40 days. Do not use in calves to be processed for veal. Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feeds is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. 

Zilpaterol hydrochloride is not for use in animals intended for breeding. Do not allow horses or other equines access to feed containing zilpaterol. Do not use in veal calves. Not to be fed to cattle in excess of 90 mg zilpaterol/head/day in complete feed. If pen consumption of complete feed exceeds 26.5 lb/head/day (90% dry matter basis), zilpaterol should not be fed in complete feed. 

Melengestrol acetate is not effective in steers and spayed heifers. Withdrawal periods of three to five days or more should be avoided to prevent the possibility that the heifers may come into estrus (heat) at loading time. 

Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Special considerations: 1) For liquid melengestrol acetate Type C feeds stored in recirculation tank systems, labeling indicates: “Recirculate immediately prior to use for no less than 10 minutes, moving not less than 1 percent of the tank contents from the bottom of the tank to the top. Recirculate daily, as directed in this paragraph even when the Type C feed is not used.” For liquid melengestrol Type C feeds stored in mechanical, air or other agitation-type tank systems: “Agitate immediately prior to use for not less than 10 minutes, creating a turbulence at the bottom of the tank that is visible at the top. Agitate daily, as directed in this paragraph, even when the Type C feed is not used.” 2) All labeling for Type C feeds containing zilpaterol hydrochloride provides the warning: The active ingredient in Zilmax® is zilpaterol hydrochloride, a beta2-adrenergic agonist. Not for use in humans. An anti-dust process has been applied to the drug product, Zilmax®, in order to greatly reduce inhalation risk. Extended handling tasks with the potential for dust generation require respiratory protection. Wear appropriate skin protection (e.g., impervious gloves, apron, overalls), if there is a potential for extended skin contact. Wear protective eyewear, if there is a potential for eye contact. If accidental eye contact occurs, immediately rinse with water and consult a physician.

FDA page: Open in Animal Drugs @ FDA

Species: Cattle, Heifers Fed In Confinement For Slaughter
Composition / specifications
Type A medicated articles containing ractopamine hydrochloride (45 g/lb), monensin (20, 30, 45, 60, 80, or 90.7 g/lb), tylosin (10, 40, or 100 g/lb), and melengestrol acetate (500 mg/lb).
Cattle (heifers fed in confinement for slaughter)
Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes and suppression of estrus (heat) in heifers fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

Feed continuously as sole rotation containing 9.8 to 24.6 grams/ton ractopamine to provide 90 to 430 mg/hd/day ractopamine; combined with monensin 10 to 40 grams per ton to provide 0.14 to 0.42 mg monensin/lb of body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/head/day; tylosin 8 to 10 grams per ton to provide 60 to 90 mg/head/day tylosin for the last 28 to 42 days on feed. Mix or top dress with medicated feed containing 0.125 to 1.0 mg melengestrol acetate per pound fed at the rate of 0.5 to 2.0 lb/head/day to provide 0.25 to 0.5 milligrams per head per day for the last 28 to 42 days on feed.

Limitations

Melengestrol acetate is not effective in steers and spayed heifers. Withdrawal periods of three to five days should be avoided to prevent the possibility that the heifers may come into estrus (heat) at time of loading. Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. 

Ractopamine HCl is not for animals intended for breeding. 

Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Special considerations: Mixing directions for liquid melengestrol acetate Type C feeds storedin recirculation tank systems, labeling indicates: “Recirculate immediately prior to use for no less than 10 minutes, moving not less than 1 percent of the tank contents from the bottom of the tankto the top. Recirculate daily, as directed in this paragraph evenwhen the Type C feed is not used." For liquid melengestrol Type C feeds stored in mechanical, air or other agitation-type tank systems:“Agitate immediately prior to use for not less than 10 minutes, creating a turbulence at the bottom of the tank that is visible at the top. Agitate daily, as directed in this paragraph, even when the Type C feed is not used.”

FDA page: Open in Animal Drugs @ FDA

Species: Cattle, Beef, Heifers Fed In Confinement For Slaughter
Cattle (heifers fed in confinement for slaughter)
Indication
For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), for the prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii; and for reduced incidence of liver abscesses caused by Fusobacterium necrophorum and Actinomyces (Corynebacterium) pyogenes.
Dosage
Melengestrol acetate, 0.25 to 0.50 milligram per head per day, plus monensin (as monensin sodium) at 50 to 360 milligrams per head per day, plus tylosin (as tylosin phosphate), 90 milligrams per head per day. To attain these amounts: Add 0.5 to 2.0 pounds per head per day of a liquid or dry medicated feed containing 0.125 to 1.0 milligram of melengestrol acetate per pound to a medicated feed containing 5 to 30 grams of monensin and 8 to 10 grams of tylosin per ton; or; Add 0.5 to 2.0 pounds per head per day of a liquid or dry medicated feed containing 0.125 to 1.0 milligram of melengestrol acetate plus 25 to 720 milligrams of monensin per pound to 4.5 to 18 pounds of a dry medicated feed containing 10 to 40 grams of tylosin per ton; or; Add 0.5 to 2.0 pounds per head per day of a dry medicated feed containing 0.125 to 1.0 milligram of melengestrol acetate (from a dry Type A article), 25 to 600 milligrams of monensin, plus 45 to 180 milligrams of tylosin per pound to a ration of non-medicated feed.
Limitations
For heifers fed in confinement for slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Beef heifers fed in confinement for slaughter
Composition / specifications
Type A medicated articles containing melengestrol acetate (200 and 500 g/lb), monensin (80 g/lb), and tylosin phosphate (40 and 100 g/lb).
Cattle, Beef, Heifers fed in confinement for slaughter
Indication
For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium pyogenes in heifers fed in confinement for slaughter
Dosage

Melengestrol acetate is added to the diet of heifers at 0.5 to 2.0 pounds per head per day of medicated feed containing 0.125 to 1.0 mg melengestrol acetate per pound to provide 0.25 to 0.5 mg melengestrol acetate per head per day. Monensin is added to feedlot cattle diets at concentrations of 10 to 40 g of monensin per ton of complete feed at a rate of 0.14 mg to 0.42 mg monensin per pound of body weight depending on the severity of coccidiosis challenge up to 480 mg per head per day.

Tylosin is added to the cattle diets at concentrations of 8 to 10 g of tylosin phosphate per ton of complete feed to provide 60 to 90 mg tylosin per head per day.

Limitations

Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle and goat feed is safe for use in cattle and goats only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing.

Feed only to cattle being fed in confinement for slaughter. Feed continuously as sole ration. A withdrawal time has not been established in pre-ruminating calves. Do not use in calves to be processed for veal.

Indication

Increased rate of weight gain, improved feed efficiency, suppression of estrus (heat),prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii,reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium pyogenes in heifers fed in confinement for slaughter.

Dosage

Melengestrol acetate (0.25 to 2 g/ton) in combination with monensin (10 to 40 g/ton) and tylosin (8 to 10 g/ton).

Limitations

Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Feed continuously as sole ration to heifers at a rate of 0.5 to 2.0 pounds per head per day to provide 0.25 to 0.5 mg/head/day melengestrol acetate and 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/head/day and 60 to 90 mg/head/day tylosin. The melengestrol acetate portion of this Type C medicated feed must be mixed into the complete feed containing 10 to 40 g/ton monensin and 8 to 10 g/ton tylosin at feeding into the amount of complete feed consumed by an animal per day. 

Melengestrol acetate is for use only in heifers being fed in confinement for slaughter. Not effective in steers or spayed heifers. Heifers fed in confinement for slaughter: Withdrawal periods of three to five days should be avoided to prevent the possibility that the heifers may come into estrus (heat) at the time of loading.

Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle and goat feed is safe for use in cattle and goats only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing.

Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite.

FDA page: Open in Animal Drugs @ FDA

Species: Beef fed In confinement for slaughter
Composition / specifications
Ractopamine hydrochloride &ndash; 45.4 g/lb</p>
<p>Monensin USP &ndash; 90.7 g/lb</p>
<p>Tylosin phosphate &ndash;100 g/lb
Cattle, Beef fed in confinement for slaughter
Indication

For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

Ractopamine hydrochloride (8.2 to 24.6 g/ton) in combination with monensin USP (10 to 40 g/ton) and tylosin phosphate (8 to 10 g/ton).

Limitations

Feed continuously as sole ration to provide 70 to 430 mg ractopamine per hd/day and 0.14 to 0.42 mg monensin per lb body weight/day (depending on severity of coccidiosis challenge, up to 480 mg/hd/day), and 60 to 90 mg tylosin per hd/day for the last 28 to 42 days on feed. Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Ractopamine HCl is not for animals intended for breeding. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

Ractopamine hydrochloride top dress (not to exceed 800 g/ton) to be fed with a ration containing 10 to 40 g/ton monensin and 8 to 10 g/ton tylosin phosphate.

Limitations

Feed a minimum of 1.0 lb/hd/day continuously to cattle fed in confinement for slaughter, to provide 70 to 400 mg/head/day ractopamine for the last 28 to 42 days on feed. Feed on top of a ration containing 10 to 40 g/ton monensin and 8 to 10 g/ton tylosin phosphate, to provide 0.14 to 0.42 mg monensin/lb body weight/day (depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day), and 60 to 90 mg/hd/day tylosin. Ractopamine HCl is not for animals intended for breeding. Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Indication

For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter during the last 28 to 42 days on feed.

Dosage

Ractopamine hydrochloride (9.8 to 24.6 g/ton) in combination with monensin (10 to 40 g/ton) and tylosin phosphate (8 to 10 g/ton).

Limitations

Feed continuously as sole ration to provide 90 to 430 mg ractopamine per hd/day and 0.14 to 0.42 mg monensin per lb body weight/day (depending on severity of coccidiosis challenge, up to 480 mg/hd/day), and 60 to 90 mg tylosin per hd/day for the last 28 to 42 days on feed. Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Ractopamine HCl is not for animals intended for breeding. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Beef heifers fed in confinement for slaughter
Composition / specifications
Ractopamine hydrochloride &ndash; 45.4 g/lb</p>
<p>Monensin USP &ndash; 90.7 g/lb</p>
<p>Tylosin phosphate &ndash;100 g/lb</p>
<p>Melengestrol acetate &ndash; 200 and 500 mg/lb
Cattle, Beef, Heifers fed in confinement for slaughter
Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes, and for suppression of estrus (heat) in heifers fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

Feed continuously as sole ration containing 9.8 to 24.6 g/ton ractopamine to provide 90 to 430 mg/hd/day ractopamine; 10 to 40 g/ton monensin to provide 0.14 to 0.42 mg monensin/lb of body weight per day, depending on severity of coccidiosis challenge, up to 480 mg/head/day; 8 to 10 g/ton tylosin to provide 60 to 90 mg/head/day tylosin for the last 28 to 42 days on feed. Mix or top dress with medicated feed containing 0.125 to 1.0 mg melengestrol acetate per pound fed at the rate of 0.5 to 2.0 lb/head/day to provide 0.25 to 0.5 mg melengestrol acetate per head per day for the last 28 to 42 days on feed.

Limitations

Melengestrol acetate is not effective in steers and spayed heifers. Withdrawal periods of three to five days should be avoided to prevent the possibility that the heifers may come into estrus (heat) at time of loading. Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Ractopamine HCl is not for animals intended for breeding.

Special considerations:

Mixing directions for liquid melengestrol acetate Type C feeds stored in recirculation tank systems, labeling indicates: “Recirculate immediately prior to use for no less than 10 minutes, moving not less than 1 percent of the tank contents from the bottom of the tank to the top. Recirculate daily, as directed in this paragraph even when the Type C feed is not used.” For liquid melengestrol Type C feeds stored in mechanical, air or other agitation-type tank systems: “Agitate immediately prior to use for not less than 10 minutes, creating a turbulence at the bottom of the tank that is visible at the top. Agitate daily, as directed in this paragraph, even when the Type C feed is not used.”


FDA page: Open in Animal Drugs @ FDA

Species: Fed in confinement for slaughter
Composition / specifications
monensin – 80 g/lb tylosin phosphate – 40 and 100 g/lb
Cattle fed in confinement for slaughter
Indication

For improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle being fed in confinement for slaughter.

Dosage

Monensin is added to feedlot cattle diets at concentrations of 10 to 40 g of monensin USP per ton of complete feed at a rate of 0.14 to 0.42 mg monensin/lb of body weight, depending on severity of coccidiosis challenge, up to 480 mg monensin/head/day.Monensin is added to feedlot cattle diets at concentrations of 5 to 40 g of monensin USP per ton of complete feed for improved feed efficiency to provide 50 to 480 mg monensin/head/day.Tylosin is added to the cattle diets at concentrations of 8 to 10 g of tylosin phosphate per ton of complete feed to provide 60 to 90 mg tylosin/head/day.

Limitations

Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Cattle, Heifers Fed In Confinement For Slaughter
Composition / specifications
Type A medicated article containing 21.77 grams of zilpaterol hydrochloride per pound. Type A medicated article containing 20, 30, 45, 60, 80, or 90.7 grams of monensin per pound. Type A medicate darticle containing 40 or 100 grams of tylosin (as tylosin phosphate) per pound. Type A medicated article containing 100 or 200 milligrams of melengestrol acetate per pound or Type A liquid medicated article containing 500 milligrams of melengestrol acetate per pound.
Cattle (heifers fed in confinement for slaughter)
Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes, and suppression of estrus (heat) in heifers fed in confinement for slaughter for the last 20 to 40 days on feed.

Dosage

Component Feed: 6.8 to 24 g/ton zilpaterol to provide 60 mg/head/day zilpaterol; 10 to 40 g/ton monensin, to provide 0.14 to 0.42 mg/lb body weight/day monensin, depending on the severity of the coccidiosis challenge, up to 480 mg/head/day monensin; and 8 to 10 g/ton tylosin to provide 60 to 90 mg/head/day tylosin; mixed or top dressed with medicated feed containing 0.125 to 1.0 mg melengestrol acetate per pound fed at the rate of 0.5 to 2.0 lb/head/day to provide 0.25 to 0.5 mg melengestrol acetate/head/day.

Limitations

Feed continuously to cattle during the last 20 to 40 dayson feed. Do not allow horses or other equines access to feed containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Zilpaterol hydrochloride is not for use in animals intended for breeding. Do not allow horses or other equines access to feed containing zilpaterol. Do not use in veal calves. Animals receiving zilpaterol hydrochloride may exhibit increased respiratory rate as well as elevated levels of creatine phosphokinase (CPK) and creatine. Melengestrol acetate is not effective in steers and spayed heifers. Withdrawal periods of three to five days or more should be avoided to prevent the possibility that the heifers may come into estrus (heat) at loading time.

Special considerations:1) For liquid melengestrol acetate Type C feeds stored in recirculation tank systems, labeling indicates: “Recirculate immediately prior to use for no less than 10 minutes, moving not less than 1 percent of the tank contents from the bottom of the tank to the top. Recirculate daily, as directed in this paragraph even when the Type C feed is not used.” For liquid melengestrol Type C feeds stored in mechanical, air or other agitation-type tank systems: “Agitate immediately prior to use for not less than 10 minutes, creating a turbulence at the bottom of the tank that is visible at the top. Agitate daily, as directed in this paragraph, even when the Type C feed is not used.”2) All labeling for Type C feeds containing zilpaterol hydrochloride provides the warning: The active ingredient in Zilmax® is zilpaterol hydrochloride, a beta2-adrenergic agonist. Not for use in humans. An anti-dust process has been applied to the drug product, Zilmax®, in order to greatly reduce inhalation risk. Extended handling tasks with the potential for dust generation require respiratory protection. Wear appropriate skin protection (e.g., impervious gloves, apron, overalls), if there is a potential for extended skin contact. Wear protective eyewear, if there is a potential for eye contact. If accidental eye contact occurs, immediately rinse with water and consult a physician.

Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes, and suppression of estrus (heat) in heifers fed in confinement for slaughter for the last 20 to 40 days on feed.

Dosage

Complete feed: 6.8 g/ton zilpaterol to provide 60 to 90 mg/head/day zilpaterol; 10 to 40 g/ton monensin, to provide 0.14 to 0.42 mg/lb body weight/day monensin, depending on the severity of the coccidiosis challenge, up to 480 mg/head/day monensin; and 8 to 10 g/ton tylosin to provide 60 to 90 mg/head/day tylosin; mixed or top dressed with medicated feed containing 0.125 to 1.0 mg melengestrol acetate per pound fed at the rate of 0.5 to 2.0 lb/head/day to provide 0.25 to 0.5 mg melengestrol acetate/head/day.

Limitations

Feed continuously as sole ration during the last 20 to 40 days on feed. Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Zilpaterol hydrochloride is not for use in animals intended for breeding. Do not allow horses or other equines access to feed containing zilpaterol. Do not use in veal calves. Not to be fed to cattle in excess of 90 mg/head/day in complete feed. If pen consumption of complete feed exceeds 26.5 lb/head/day (90 percent dry matter basis), zilpaterol should not be fed in complete feed. Animals receiving zilpaterol hydrochloride may exhibit increased respiratory rate as well as elevated levels of creatine phosphokinase (CPK) and creatine.Melengestrol acetate is not effective in steers and spayed heifers. Withdrawal periods of three to five days or more should be avoided to prevent the possibility that the heifers may come into estrus (heat) at loading time.

FDA page: Open in Animal Drugs @ FDA

Species: Beef fed In confinement for slaughter
Label highlights
Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 20 to 40 days on feed.

Dosage

Zilpaterol hydrochloride is fed at a concentration of 6.8 g of zilpaterol hydrochloride per ton of complete feed to provide 60 to 90 mg zilpaterol/head/day in cattle fed in confinement for slaughter during the last 20 to 40 days on feed.

Monensin USP is added to diets for cattle fed in confinement for slaughter at concentrations of 10 to 40 g of monensin USP per ton of complete feed at a rate of 0.14 to 0.42 mg monensin/lb of body weight, depending on severity of coccidiosis challenge, up to 480 mg/head/day. 

Tylosin phosphate is added to the cattle diets at concentrations of 8 to 10 g of tylosin phosphate per ton of complete feed to provide 60 to 90 mg tylosin/head/day.

Limitations

Do not use in calves to be processed for veal. Feed continuously as the sole ration during the last 20 to 40 days on feed. Not to be fed to cattle in excess of 90 mg zilpaterol/head/day in complete feed. If pen consumption of complete feed exceeds 26.5 lb/head/day (90 percent dry matter basis), zilpaterol should not be fed in complete feed.

Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Special considerations:

1) Labeling of Type B and Type C cattle feeds shall bear the following: (i) Do not allow horses or other equines access to feed containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. (ii) Zilpaterol hydrochloride is not for use in animals intended for breeding. (iii) Do not allow horses or other equines access to feed containing zilpaterol. (iv) Do not use in veal calves.

2) Type B Liquid Feeds can be manufactured containing 68 to 680 g zilpaterol hydrochloride/ton. The liquid Type B feeds must be maintained at a pH of 3.8 to 7.5. For liquid feeds stored in recirculating tank systems: Recirculate immediately prior to use for not less than 10 minutes, moving not less than 1 percent of the tank contents per minute from the bottom of the tank to the top. Recirculate daily as described even when not used. For liquid feeds stored in mechanical, air or other agitation-type tank systems: Agitate immediately prior to use for not less than 10 minutes, creating turbulence at the bottom of the tank that is visible at the top. Agitate daily as described even when not used.

FDA page: Open in Animal Drugs @ FDA

Species: Beef heifers fed in confinement for slaughter
Composition / specifications
Zilpaterol hydrochloride &ndash; 21.77 g/lb</p>
<p>Monensin USP &ndash; 80 g/lb</p>
<p>Tylosin phosphate &ndash; 40 and 100 g/lb</p>
<p>Melengestrol acetate &ndash; 100 and 200 mg/lb (dry) and 500 mg/lb (liquid)
Label highlights
Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes and suppression of estrus (heat) in heifers fed in confinement for slaughter for the last 20 to 40 days on feed.

Dosage
Limitations

Feed continuously as sole ration during the last 20 to 40 days on feed. Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. 

Zilpaterol hydrochloride is not for use in animals intended for breeding. Do not allow horses or other equines access to feed containing zilpaterol. Do not use in veal calves. Not to be fed to cattle in excess of 90 mg/head/day in complete feed. If pen consumption of complete feed exceeds 26.5 lb/head/day (90 percent dry matter basis), zilpaterol should not be fed in complete feed. Animals receiving zilpaterol hydrochloride may exhibit increased respiratory rate as well as elevated levels of creatine phosphokinase (CPK) and creatine. 

Melengestrol acetate is not effective in steers and spayed heifers. Withdrawal periods of three to five days or more should be avoided to prevent the possibility that the heifers may come into estrus (heat) at loading time.

Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Special considerations: 1) For liquid melengestrol acetate Type C feeds stored in recirculation tank systems, labeling indicates: “Recirculate immediately prior to use for no less than 10 minutes, moving not less than 1 percent of the tank contents from the bottom of the tank to the top. Recirculate daily, as directed in this paragraph even when the Type C feed is not used.” For liquid melengestrol Type C feeds stored in mechanical, air or other agitation-type tank systems: “Agitate immediately prior to use for not less than 10 minutes, creating a turbulence at the bottom of the tank that is visible at the top. Agitate daily, as directed in this paragraph, even when the Type C feed is not used.”

2) All labeling for Type C feeds containing zilpaterol hydrochloride provides the warning: The active ingredient in Zilmax® is zilpaterol hydrochloride, a beta2-adrenergic agonist. Not for use in humans. An anti-dust process has been applied to the drug product, Zilmax®, in order to greatly reduce inhalation risk. Extended handling tasks with the potential for dust generation require respiratory protection. Wear appropriate skin protection (e.g., impervious gloves, apron, overalls), if there is a potential for extended skin contact. Wear protective eyewear, if there is a potential for eye contact. If accidental eye contact occurs, immediately rinse with water and consult a physician.

FDA page: Open in Animal Drugs @ FDA

Species: Cattle, Heifers Fed In Confinement For Slaughter
Composition / specifications
Type A medicated article containing 100 or 200 milligrams of melengestrol acetate per pound or Type A liquid medicated article containing 500 milligrams of melengestrol acetate per pound. Type A medicated article containing 68, 91, or 150 grams of lasalocid (as lasalocid sodium) per pound or Type A liquid medicated article containing 90.7 grams of lasalocid (as lasalocid sodium) per pound. Type A medicated article containing 40 or 100 grams of tylosin (as tylosin phosphate) per pound.
Cattle (heifers)
Indication

For increased rate of weight gain, improved feed efficiency, and suppression of estrus (heat) in heifers fed in confinement for slaughter.

Dosage

Feed 0.25 to 2.0 g/ton melengestrol acetate to heifers at the rate of 0.5 to 2.0 lb/hd/day as a top dress or mixed into a complete feed to provide 0.25 to 0.5 mg melengestrol acetate per head per day and 100 to 1440 g/ton lasalocid to provide 100 to 360 mg lasalocid per head per day. Melengestrol acetate and lasalocid may be fed continuously throughout the time the heifers are being grown and finished for slaughter.

May be fed to heifers in combination with a complete feed containing 8 to 10 g of tylosin per ton for reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes.

Limitations

When tylosin is fed in combination with melengestrol acetate and lasalocid, the level of tylosin is limited to 90 mg/hd/day. Melengestrol acetate is only for use in heifers being fed in confinement for slaughter. Not effective in steers and spayed heifers. This combination may only be marketed as a pelleted product. Do not allow horses or other equines access to premixes or supplements containing lasalocid, as ingestion may be fatal. The safety of lasalocid in unapproved species has not been established. Mixing errors resulting in excessive lasalocid concentrations could be fatal to cattle and sheep. When mixing and handling lasalocid, use protective clothing, impervious gloves and a dust mask, avoid contact with eyes. Operators should wash hands thoroughly with soap and water after handling. Use melengestrol acetate only as directed.

Indication

For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), and for reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in heifers fed in confinement for slaughter.

Dosage

Feed 0.25 to 2.0 g/ton melengestrol acetate to heifers at the rate of 0.5 to 2.0 lb/hd/day as a top dress or mixed into a complete feed to provide 0.25 to 0.5 mg melengestrol acetate per head lasalocid per day and 100 to 1440 g/ton lasalocid to provide 100 to 360 mg lasalocid per head per day and 90 to 360 g/ton tylosin to provide 90 mg tylosin per head per day. Melengestrol acetate, lasalocid, and tylosin may be fed continuously throughout the time the heifers are being grown and finished for slaughter.

Limitations

When tylosin is fed in combination with melengestrol acetate and lasalocid, the level of tylosin is limited to 90 mg/hd/day. For use only in heifers being fed in confinement for slaughter. Not effective in steers and spayed heifers. This combination may only be marketed as a pelleted product. Do not allow horses or other equines access to premixes or supplements containing lasalocid, as ingestion may be fatal. The safety of lasalocid in unapproved species has not been established. Mixing errors resulting in excessive concentrations of lasalocid could be fatal to cattle and sheep. When mixing and handling lasalocid, use protective clothing, impervious gloves and a dust mask, avoid contact with eyes. Operators should wash hands thoroughly with soap and water after handling. Use melengestrol acetate only as directed.

FDA page: Open in Animal Drugs @ FDA

Species: Growing beef steers and heifers fed in confinement for slaughter
Composition / specifications
Type A medicated article containing 27.2 grams of decoquinate per pound. Type A medicated article containing 20, 30, 45, 60, 80, or 90.7 grams of monensin per pound. Type A medicated article containing 40 or 100 grams of tylosin (as tylosin phosphate) per pound.
Growing beef steers and heifers fed in confinement for slaughter
Indication

For the prevention of coccidiosis caused by Eimeria bovis and E. zuernii, for improved feed efficiency, and for reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in growing beef steers and heifers fed in confinement for slaughter.

Dosage

Feed as the sole ration to provide 22.7 mg of decoquinate per 100 lb. of body weight per day, 50 to 360 mg of monensin per head per day, and 60 to 90 mg tylosin (as tylosin phosphate). Feed for at least 28 days during periods of coccidiosis exposure or when experience indicates that coccidiosis is likely to be a hazard.

Limitations

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Species: No use class stated or implied • Beef
Composition / specifications
Type A medicated articles contain 40 grams tylosin (as tylosin phosphate) per pound
Cattle (beef)
Indication

For reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes.

Dosage
8 - 10 grams per ton of feed.
Limitations

As tylosin phosphate. Each animal must receive not more than 90 mg/head/day and not less than 60 mg/head/day. Feed continuously as sole ration.

Swine
Indication

Feed 100 g of tylosin per ton (2.5 pounds Tylan 40 per ton) of complete feed. Feed as the sole ration.

Dosage

For reduction in severity of effects of atrophic rhinitis.

Limitations
Indication

For control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis.

Dosage

Feed 100 g of tylosin per ton (2.5 pounds Tylan 40 per ton) of complete feed for 21 days. Alternatively, feed 100 g of tylosin per ton (2.5 pounds Tylan 40 per ton) of complete feed for at least three weeks, followed by 40 g tylosin per ton of complete feed until pigs reach market weight. Alternatively, feed 40 to 100 grams of tylosin (1.0 to 2.5 pounds of Tylan 40) per ton of complete feed for 2 to 6 weeks immediately after medicating with 250 mg tylosin (as Tylan Soluble) per gallon in drinking water for 3 to 10 days. Feed as the sole ration when feeding Tylan.

Limitations
Indication

For control of swine dysentery associated with Brachyspira hyodysenteriae.

Dosage

Feed 100 g of tylosin per ton (2.5 pounds Tylan 40 per ton) of complete feed for at least three weeks. Follow with 40 g tylosin per ton (1 pound Tylan 40 per ton) of complete feed until pigs reach market weight.

Limitations
Indication

For the treatment and control of swine dysentery associated with Brachyspira hyodysenteriae immediately after medicating with Tylan Soluble (tylosin) drinking water.

Dosage

For the treatment and control of swine dysentery. Feed 40 to 100 grams of tylosin (1.0 to 2.5 pounds of Tylan 40) per ton of complete feed for 2 to 6 weeks immediately after medicating with 250 mg tylosin (as Tylan Soluble) per gallon in drinking water for 3 to 10 days.

Limitations

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Species: No use class stated or implied
Composition / specifications
Type A medicated article containing both tylosin (10 g/lb) and sulfamethazine (10 g/lb).
Swine
Indication

For reduction in the severity of effects of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery associated with Brachyspira hyodysenteriae; and control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Arcanobacterium pyogenes).

Dosage
100 grams tylosin per ton of feed plus 100 grams sulfamethazine per ton of feed.
Limitations

Withdraw 15 days before swine are slaughtered.

Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Growing beef heifers fed in confinement for slaughter
Composition / specifications
MGA® 200 (dry formulation): 200 mg per lb of melengestrol acetate; MGA® 500 (liquid formulation): 500 mg per lb of melengestrol acetate; Experior™: 10 g per kg (4.54 g per lb) and 50 g per kg (22.7 g per lb) of lubabegron (as lubabegron fumarate) Monovet®: 90.7 g per lb of monensin; Tylovet®: 40 g per lb and 100 g per lb of tylosin (as tylosin phosphate)
Growing beef heifers fed in confinement for slaughter
Indication

For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), for reduction of ammonia gas emissions per pound of live weight and hot carcass weight, and for the prevention and control of coccidiosis caused by Eimeria bovis and Eimeria zuernii, and for reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in growing beef heifers fed in confinement for slaughter during the last 14 to 91 days on feed.

Dosage

0.25 to 2 g/ton of melengestrol acetate (as MGA® 200 or MGA® 500) to provide 0.25 to 0.5 mg melengestrol acetate per head per day; 1.25 to 4.54 g/ton of lubabegron (as Experior™) to provide 13 to 90 mg lubabegron per head per day; 10 to 40 g/ton of monensin (as Monovet®) to provide 0.14 to 0.42 mg monensin per pound of body weight per day, depending upon severity of challenge, up to a maximum of 480 mg monensin per head per day; and 8 to 10 g/ton of tylosin (as Tylovet®) to provide 60 to 90 mg tylosin per head per day. The melengestrol acetate Type C top-dress medicated feed (0.5 to 2 lb per head per day) must be trop dressed onto or mixed at feeding with a Type C medicated feed containing lubabegron and monensin and tylosin. Feed as the sole ration during the last 14 to 91 days on feed.


Limitations

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Species: No use class stated or implied • Beef • Calves • Dairy, non-lactating
Composition / specifications
Each mL contains 200 mg of tylosin activity (as tylosin base) in 50% propylene glycol, 4% benzyl alcohol and water for injection, q.s.
Cattle (beef and nonlactating dairy)
Indication

Treatment of bovine respiratory complex (shipping fever, pneumonia) usually associated with Pasteurella multocida and Actinomyces pyogenes; foot rot (necrotic pododermatitis) and calf diphtheria caused by Fusobacterium necrophorum and metritis caused by Actinomyces pyogenes.

Dosage
8 milligrams per pound of body weight intramuscularly, once daily.
Limitations

Treatment should be continued 24 hours after symptoms of the disease have stopped, not to exceed 5 days. Continue treatment 24 hours after symptoms disappear. Do not inject more than 10 milliliters per site. Do not use in lactating dairy cattle. Use a 50-milligram-per-milliliter solution for calves weighing less than 200 pounds. Do not administer within 21 days of slaughter. A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal.

Swine
Indication

Treatment of swine arthritis caused by Mycoplasma hyosynoviae; swine pneumonia caused by Pasteurella species; swine erysipelas caused by Erysipelothrix rhusiopathiae; acute swine dysentery associated with Brachyspira (formerly Serpulina or Treponema) hyodysenteriae when followed by appropriate medication in the drinking water and/or feed.

Dosage
4 milligrams per pound of body weight intramuscularly, twice daily.
Limitations

Treatment should be continued 24 hours after symptoms of the disease have stopped, not to exceed 3 days. Continue treatment 24 hours after symptoms disappear. Do not inject more than 5 milliliters per site. Do not administer within 14 days of slaughter. If tylosin medicated drinking water is used as followup treatment for swine dysentery, the animal should thereafter receive feed containing 40 to 100 grams of tylosin per ton for 2 weeks to assure depletion of tissue residues.

FDA page: Open in Animal Drugs @ FDA

Species: Growing beef heifers fed in confinement for slaughter
Composition / specifications
MGA® 200 (dry formulation): 200 mg per lb of melengestrol acetate; MGA® 500 (liquid formulation): 500 mg per lb of melengestrol acetate; Experior™: 10 g per kg (4.54 g per lb) and 50 g per kg (22.7 g per lb) of lubabegron (as lubabegron fumarate); Rumensin™: 90.7 g per lb of monensin, USP Tylan™: 40 g per lb and 100 g per lb of tylosin (as tylosin phosphate)
Growing beef heifers fed in confinement for slaughter
Indication

For increased rate of weight gain, improved feed efficiency, suppression of estrus heat), for reduction of ammonia gas emissions per pound of live weight and hot carcass weight, and for the prevention and control of coccidiosis caused by Eimeria bovis and Eimeria zuernii and for reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in growing beef heifers fed in confinement for slaughter during the last to 91 days on feed.

Dosage

0.25 to 2 g/ton of melengestrol acetate (as MGA® 200 or MGA® 500) to provide 0.25 to 0.5 mg melengestrol acetate per head per day, 1.25 to 4.54 g/ton of lubabegron (as lubabegron fumarate) (as Experior™) to provide 13 to 90 mg lubabegron per head per day, 10 to 40 g/ton of monensin (as Rumensin™) to provide 0.14 to 0.42 mg monensin per pound of body weight per day, depending upon severity of challenge, up to a maximum of 480 mg monensin per head per day, and 8 to 10 g/ton of tylosin (as tylosin phosphate) (as Tylan™) to provide 60 to 90 mg tylosin per head per day.

The melengestrol acetate Type C top-dress medicated feed (0.5 to 2 lb(s) per head per day) must be top dressed onto or mixed at feeding with a Type C medicated feed containing lubabegron and monensin and tylosin. Feed as the sole ration during the last 14 to 91 days on feed.

Limitations

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Species: Finishing
Composition / specifications
Ractopamine hydrochloride &ndash; 9 or 45.4 g/lb and Tylosin phosphate &ndash; 40 and 100 g/lb
Swine
Indication

For increased rate of weight gain, improved feed efficiency and increased carcass leanness in finishing swine, weighing not less than 150 lbs, fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter; for control of swine dysentery associated with Brachyspira hyodysenteriae; and for control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis.

Dosage

4.5 to 9 g ractopamine hydrochloride and 40 or 100 g tylosin phosphate per ton of Type C medicated feed.

Limitations

Feed continuously as the sole ration to finishing swine weighing not less than 150 lbs for the last 45 to 90 lbs (group average) of weight gain prior to slaughter. Include 100 g/ton of tylosin for at least 3 weeks, followed by 40 g/ton until market weight. No increased benefit has been shown when ractopamine concentrations in the diet are greater than 4.5 g/ton. Ractopamine may increase the number of injured and/or fatigued pigs during marketing. Not for animals intended for breeding. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.


Indication

For increased rate of weight gain, improved feed efficiency and increased carcass leanness in finishing swine, weighing not less than 150 lbs, fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter; for treatment and control of swine dysentery associated with Brachyspira hyodysenteriae; and for control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis.

Dosage

4.5 to 9 g ractopamine hydrochloride and 40 to 100 g tylosin phosphate per ton of Type C medicated feed.

Limitations

Feed continuously as the sole ration to finishing swine weighing not less than 150 lbs for the last 45 to 90 lbs (group average) of weight gain prior to slaughter. Feed 40 to 100 grams of tylosin per ton of complete feed for 2 to 6 weeks immediately after medicating with 250 mg tylosin tartrate (Tylan™ Soluble) per gallon in drinking water for 3 to 10 days. No increased benefit has been shown when ractopamine concentrations in the diet are greater than 4.5 g/ton. Ractopamine may increase the number of injured and/or fatigued pigs during marketing. Not for animals intended for breeding. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Indication

For increased rate of weight gain, improved feed efficiency and increased carcass leanness in finishing swine, weighing not less than 150 lbs, fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter, and for control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis.

Dosage

Ractopamine hydrochloride (4.5 to 9.0 g/ton) in combination with tylosin phosphate (40 or 100 g/ton). Feed 100 g/ton continuously as sole ration for at least 3 weeks followed by 40 g/ton until market weight.

Limitations

Feed continuously as the sole ration to finishing swine weighing not less than 150 lbs for the last 45 to 90 lbs (group average) of weight gain prior to slaughter. Include 100 g/ton of tylosin for 21 days. No increased benefit has been shown when ractopamine concentrations in the diet are greater than 4.5 g/ton. Ractopamine may increase the number of injured and/or fatigued pigs during marketing. Not for animals intended for breeding. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Finishing
Composition / specifications
Ractopamine hydrochloride - 9 g/lb</p>
<p>Tylosin phosphate - 100 g/lb
Label highlights
Indication

For increased rate of weight gain, improved feed efficiency and increased carcass leanness in finishing swine, weighing not less than 150 lbs, fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter; and for control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis.

Dosage
Ractopamine hydrochloride (4.5 to 9.0 g/ton) in combination with tylosin phosphate 100 g/ton.
Limitations

Feed continuously as the sole ration to finishing swine weighing not less than 150 lbs for the last 45 to 90 lbs (group average) of weight gain prior to slaughter. Include 100 g/ton of tylosin for 21 days. Not for animals intended for breeding. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Indication

For increased rate of weight gain, improved feed efficiency and increased carcass leanness in finishing swine, weighing not less than 150 lbs, fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter; for control of swine dysentery associated with Brachyspira hyodysenteriae; and for control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis.

Dosage

Ractopamine hydrochloride (4.5 to 9.0 g/ton) in combination with tylosin phosphate (40 or 100 g/ton).

Limitations

Feed continuously as the sole ration to finishing swine weighing not less than 150 lbs for the last 45 to 90 lbs (group average) of weight gain prior to slaughter. Feed 40 to 100 grams of tylosin per ton of complete feed for 2 to 6 weeks immediately after medicating with 250 mg tylosin tartrate per gallon in drinking water for 3 to 10 days. Not for animals intended for breeding. Ractopamine may increase the number of injured and/or fatigued pigs during marketing. Not for animals intended for breeding. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Indication
For increased rate of weight gain, improved feed efficiency and increased carcass leanness in finishing swine, weighing not less than 150 lbs, fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter; for treatment and control of swine dysentery associated with Brachyspira hyodysenteriae; and for control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis.
Dosage

4.5 to 9 g Ractopamine hydrochloride and 40 to 100 g tylosin phosphate per ton of Type C medicated feed. 

Limitations

Feed continuously as the sole ration to finishing swine weighing not less than 150 lbs for the last 45 to 90 lbs (group average) of weight gain prior to slaughter. Feed 40 to 100 grams of tylosin per ton of complete feed for 2 to 6 weeks immediately after medicating with 250 mg tylosin tartrate per gallon in drinking water for 3 to 10 days. No increased benefit has been shown when ractopamine concentrations in the diet are greater than 4.5 g/ton. Ractopamine may increase the number of injured and/or fatigued pigs during marketing. Not for animals intended for breeding. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Beef heifers fed in confinement for slaughter
Composition / specifications
Type A medicated article containing 100 or 200 milligrams of melengestrol acetate per pound or Type A liquid medicated article containing 500 milligrams of melengestrol acetate per pound. Type A medicated article containing 20, 30, 45, 60, 80, or 90.7 grams of monensin per pound. Type A medicated article containing 40 or 100 grams of tylosin (as tylosin phosphate) per pound.
Cattle (heifers fed in confinement for slaughter
Indication

Increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium pyogenes in heifers fed in confinement for slaughter.

Dosage

Melengestrol acetate (0.25 to 2 g/ton) in combination with monensin (10 to 40 g/ton) and tylosin (8 to 10 g/ton).

Limitations

Feed continuously as sole ration to heifers at a rate of 0.5 to 2.0 pounds per head per day to provide 0.25 to 0.5 mg/head/day melengestrol acetate and 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/head/day and 60 to 90 mg/head/day tylosin. The melengestrol acetate portion of this Type C medicatedfeed must be mixed into the complete feed containing 10 to 40 g/ton monensin and 8 to 10 g/ton tylosin at feeding into the amount of complete feed consumed by an animal per day.Melengestrol acetate is for use only in heifers being fed in confinement for slaughter. Not effective in steers or spayed heifers. Heifers fed in confinement for slaughter: Withdrawal periods of three to five days should be avoided to prevent the possibility that the heifers may come into estrus (heat) at the time of loading.Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle and goat feed is safe for use in cattle and goats only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing.Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite.

Indication

Increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium pyogenes in heifers fed in confinement for slaughter.

Dosage

Melengestrol acetate (0.25 to 2 g/ton) in combination with monensin (10 to 40 g/ton) and tylosin (8 to 10 g/ton).

Limitations

Feed continuously as sole ration to heifers at a rate of 0.5 to 2.0 pounds per head per day to provide 0.25 to 0.5 mg/head/day melengestrol acetate and 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/head/day and 60 to 90 mg/head/day tylosin. The melengestrol acetate portion of this Type C medicated feed must be mixed into the complete feed containing 10 to 40 g/ton monensin and 8 to 10 g/ton tylosin at feeding into the amount of complete feed consumed by an animal per day. Melengestrol acetate is for use only in heifers being fed in confinement for slaughter. Not effective in steers or spayed heifers. Heifers fed in confinement for slaughter: Withdrawal periods of three to five days should be avoided to prevent the possibility that the heifers may come into estrus (heat) at the time of loading.Inadequate mixing (recirculation or agitation) of monensin liquid Type C medicated feed has resulted in increased monensin concentration, which has been fatal to cattle. Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle and goat feed is safe for use in cattle and goats only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing.Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite.

FDA page: Open in Animal Drugs @ FDA

Species: Beef heifers fed in confinement for slaughter
Composition / specifications
Type A medicated article containing 100 or 200 milligrams of melengestrol acetate per pound or Type A liquid medicated article containing 500 milligrams of melengestrol acetate per pound. Type A medicated article containing 40 or 100 grams of tylosin (as tylosin phosphate) per pound.
Cattle (heifers)
Indication

For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), and for reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes.

Dosage

Each pound contains 0.125 to 1.0 mg melengestrol acetate and 45 to 180 mg of tylosin. Feed to heifers at a rate of 0.5 to 2.0 pounds per head per day to provide 0.25 to 0.5 mg melengestrol acetate and 60 to 90 mg tylosin per head per day. Prior to feeding, this Type C product must be top-dressed onto a complete feed or mixed into the amount of complete feed consumed by an animal per day.

Limitations

Feed continuously as sole ration. MGA is for use only in heifers being fed in confinement for slaughter. Not effective in steers and spayed heifers. When mixing and handling tylosin, use protective clothing, impervious gloves and a dust mask. Operators should wash thoroughly with soap and water after handling. If accidental eye contact occurs, immediately rinse thoroughly with water.

FDA page: Open in Animal Drugs @ FDA

Species: Beef steers fed in confinement for slaughter • Heifers fed in confinement for slaughter
Composition / specifications
Experior™: 10 g/kg (4.54 g/lb) and 50 g/kg (22.7 g/lb) of lubabegron (as lubabegron fumarate); Monovet®: 90.7 g/lb of monensin; Tylovet®: 40 g/lb and 100 g/lb of tylosin (as tylosin phosphate)
Beef steers and heifers fed in confinement for slaughter
Indication

For reduction of ammonia gas emissions per pound of live weight and hot carcass weight, improved feed efficiency, and reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in beef steers and heifers fed in confinement for slaughter during the last 14 to 91 days on feed.

Dosage

1.25 to 4.54 g/ton to provide 13 to 90 mg/hd/day of lubabegron (as Experior™), 5 to 40 g/ton to provide 50 to 480 mg/hd/day of monensin (as Monovet®), and 8 to 10 g/ton to provide 60 to 90 mg/hd/day of tylosin (as Tylovet®). Feed continuously as the sole ration during the last 14 to 91 days on feed.

Limitations
Indication

For reduction of ammonia gas emissions per pound of live weight and hot carcass weight, prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii, and reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in beef steers and heifers fed in confinement for slaughter during the last 14 to 91 days on feed.

Dosage

1.25 to 4.54 g/ton to provide 13 to 90 mg/hd/day of lubabegron (as Experior™), 10 to 40 g/ton to provide 0.14 to 0.42 mg/lb body weight per day, depending upon severity of coccidiosis challenge, up to 480 mg/hd/day, ofmonensin (as Monovet®), and 8 to 10 g/ton to provide 60 to 90 mg/hd/day of tylosin (as Tylovet®). Feed continuously as the sole ration during the last 14 to 91 days on feed.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Growing beef heifers fed in confinement for slaughter • Growing beef steers fed in confinement for slaughter
Composition / specifications
Experior™: 10 g/kg (4.54 g/lb); Rumensin™: 90.7 g/lb; Tylan™: 100 g/lb
Beef steers and heifers fed in confinement for slaughter
Indication

For reduction of ammonia gas emissions per pound of live weight and hot carcass weight, prevention and control of coccidiosis caused by Eimeria bovis and Eimeria zuernii, and reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in beef steers and heifers fed in confinement for slaughter during the last 14 to 91 days on feed.

Dosage

1.25 to 4.54 g/ton to provide 13 to 90 mg/hd/day of Experior™; 10 to 40 g/ton to provide 0.14 to 0.42 mg/lb body weight per day, depending upon severity of coccidiosis challenge, up to 480 mg/hd/day, of Rumensin™; and 8 to 10 g/ton to provide 60 to 90 mg/hd/day of Tylan™

Feed continuously as sole ration during the last 14 to 91 days on feed.

Limitations
Indication

For reduction of ammonia gas emissions per pound of live weight and hot carcass weight, improved feed efficiency, and reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in beef steers and heifers fed in confinement for slaughter during the last 14 to 91 days on feed.

Dosage

1.25 to 4.54 g/ton to provide 13 to 90 mg/hd/day of Experior™; 5 to 40 g/ton to provide 50 to 480 mg/hd/day of Rumensin™; and 8 to 10 g/ton to provide 60 to 90 mg/hd/day of Tylan™.

Feed continuously as sole ration during the last 14 to 91 days on feed.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Beef calves at least 45 days old and up to 400 lbs of body weight
Composition / specifications
Each implant consists of 100 mg progesterone, 10 mg estradiol benzoate, and 20 mg tylosin tartrate.
Beef calves 45 days of age and older and weighing up to 400 lbs
Indication

For increased rate of weight gain in beef calves 45 days of age and older and weighing up to 400 lbs. This implant is not approved for repeated implantation (reimplantation) with this or any other cattle ear implant as safety and effectiveness has not been evaluated.

Dosage

Administer one implant containing 100 mg progesterone, 10 mg estradiol benzoate, and 29 mg tylosin tartrate (5 pellets) to each calf by subcutaneous implantation in the middle-third of the ear

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Growing beef steers and heifers on pasture (stocker, feeder, and slaughter)
Composition / specifications
Component™ TE-G contains 40 mg trenbolone acetate and 8 mg estradiol. Each implant consists of 2 pellets.are included in the CFR for this product.
Growing beef steers and heifers on pasture (stocker, feeder, and slaughter)
Indication

For increased rate of weight gain. Not approved for repeated implantation (reimplantation) with this or any other cattle ear implant in growing beef steers and heifers on pasture (stocker, feeder, and slaughter). Safety and effectiveness following reimplantation have not been evaluated.

Dosage

Administer one implant containing 40 mg trenbolone acetate and 8 mg estradiol (2 pellets) to each steer or heifer by subcutaneous implantation in the middle-third of the ear.

Limitations
Implant subcutaneously in ear only. Do not use in animals intended for subsequent breeding or in dairy animals. Safety and effectiveness have not been established in veal calves. A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal.

FDA page: Open in Animal Drugs @ FDA

Species: Finishing
Composition / specifications
Ractopamine hydrochloride – 9 g/lb and 45.4 g/lb and Tylosin phosphate – 40 g/lb and 100 g/lb
Swine
Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, and control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis in finishing swine weighing at least 150 lbs and fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter. No increased benefit has been shown when ractopamine hydrochloride concentrations in the diet are greater than 4.5 g/ton (5 ppm).

Dosage

Ractopamine hydrochloride 4.5 to 9 g/ton and tylosin phosphate 100 g/ton per ton of Type C medicated feed.

Limitations

Feed continuously as the sole ration to finishing swine weighing at least 150 lbs for the last 45 to 90 lbs (group average) of weight gain prior to slaughter. Include 100 g/ton of tylosin for 21 days. Ractopamine hydrochloride may increase the number of injured and/or fatigued pigs during marketing. Not for animals intended for breeding. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite.

Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, the treatment and control of swine dysentery associated with Brachyspira hyodysenteriae, and control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis in finishing swine weighing at least 150 lbs and fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter. No increased benefit has been shown when ractopamine hydrochloride concentrations in the diet are greater than 4.5 g/ton (5 ppm).

Dosage

Ractopamine hydrochloride 4.5 to 9.0 g/ton and tylosin phosphate 40 to 100 g/ton per ton of Type C medicated feed.

Limitations

Feed continuously as the sole ration to finishing swine weighing at least 150 lbs for the last 45 to 90 lbs (group average) of weight gain prior to slaughter. Feed 40 to 100 grams of tylosin per ton of complete feed for 2 to 6 weeks immediately after medicating with 250 mg tylosin tartrate (Tylovet®, Soluble) per gallon in drinking water for 3 to 10 days. Ractopamine hydrochloride may increase the number of injured and/or fatigued pigs during marketing. Not for animals intended for breeding. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite.





Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, control of swine dysentery associated with Brachyspira hyodysenteriae, and control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis in finishing swine weighing at least 150 lbs and fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter. No increased benefit has been shown when ractopamine hydrochloride concentrations in the diet are greater than 4.5 g/ton (5 ppm).

Dosage

Ractopamine hydrochloride 4.5 to 9 g/ton and tylosin phosphate 100 g/ton per ton of Type C medicated feed.

Limitations

Feed continuously as the sole ration to finishing swine weighing at least 150 lbs for the last 45 to 90 lbs (group average) of weight gain prior to slaughter. Include 100 g/ton of tylosin for at least 3 weeks, followed by 40 g/ton until market weight. Ractopamine hydrochloride may increase the number of injured and/or fatigued pigs during marketing. Not for animals intended for breeding. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite.

FDA page: Open in Animal Drugs @ FDA

Species: Growing beef steers and heifers fed in confinement for slaughter
Composition / specifications
Component™ TE-200 with Tylan™ contains 200 mg trenbolone acetate and 20 mg of estradiol and 29 mg tylosin tartrate. Each implant consists of 11 pellets.
Growing beef steers and heifers fed in confinement for slaughter
Indication

For increased rate of weight gain and improved feed efficiency in growing beef steers and heifers fed in confinement for slaughter. Not approved for repeated implantation (reimplantation) with this or any other cattle ear implant in growing beef steers and heifers fed in confinement for slaughter. Safety and effectiveness following reimplantation have not been evaluated.

Dosage

Administer one implant containing 200 mg trenbolone acetate, 20 mg estradiol, and 29 mg tylosin tartrate (11 pellets) to each steer or heifer by subcutaneous implantation in the middle-third of the ear.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Beef heifers fed in confinement for slaughter • Beef steers fed in confinement for slaughter
Cattle (heifers fed in confinement for slaughter)
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
200 mg of trenbolone acetate (one implant consisting of 11 pellets, each of 10 pellets containing 20 mg of trenbolone acetate, and 1 pellet containing 29 mg of tylosin tartrate) per implant dose. Use last 63 days before slaughter.
Limitations
Implant subcutaneously in ear only. Do not use in animals intended for subsequent breeding or in dairy animals. A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal.

FDA page: Open in Animal Drugs @ FDA

Species: Honey Bees • No use class stated or implied • Broilers • Replacements • Excluding turkeys producing eggs for human consumption
Composition / specifications
100 g of tylosin base per pouch or jar
Broiler and replacement chickens
Indication

As an aid in the treatment of chronic respiratory disease (CRD) associated with Mycoplasma gallisepticum sensitive to tylosin in broiler and replacement chickens. For the control of CRD associated with Mycoplasma gallisepticum sensitive to tylosin at the time of vaccination or other stress in chickens. For the control of CRD associated with Mycoplasma synoviae sensitive to tylosin in broiler chickens.

Dosage

2 grams per gallon; should be treated for three days; however, treatment may be administered for one to five days depending on the severity of infection. Treated chickens should consume enough medicated drinking water to provide 50 milligrams (mg) tylosin per pound body weight per day.

Limitations

Only medicated water should be available to birds. Chickens must not be slaughtered for food within 24 hours after treatment. Do not use in layers producing eggs for human consumption.

Broiler chickens
Indication

For the control of mortality caused by necrotic enteritis (NE) associated with Clostridium perfringens in broiler chickens.

Dosage

851 to 1,419 mg/gallon (225 to 375 ppm) in drinking water for five consecutive days.

Limitations
Turkeys
Indication
For the reduction in severity of effects of infectious sinusitis associated with Mycoplasma gallisepticum.
Dosage

2 grams per gallon; should be treated for three days; however, treatment may be administered for 2 to 5 days depending on the severity of infection. Treated turkeys should consume enough medicated drinking water to provide 60 mg tylosin base per pound body weight per day. Only medicated water should be available to birds.

Limitations

Only medicated water should be available to birds. Turkeys must not be slaughtered for food within 5 days after treatment. Do not use in layers producing eggs for human consumption.

Swine
Indication

For the treatment and control of swine dysentery associated with Brachyspira hyodysenteriae. For the treatment and control of swine dysentery associated with Brachyspira hyodysenteriae when followed immediately by tylosin phosphate Type A medicated article in feed. For the control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis when followed immediately by tylosin phosphate Type A medicated article in feed.

Dosage

For the treatment and control of swine dysentery medicate with 250 mg tylosin per gallon in drinking water for 3 to 10 days, depending upon severity of infection. Alternatively, medicate with 250 mg tylosin per gallon in drinking water for 3 to 10 days, followed by 40 to 100 g of tylosin per ton of complete feed (Type C medicated feed manufactured from tylosin phosphate Type A medicated article) for 2 to 6 weeks. For control of porcine proliferative enteropathies (PPE, ileitis) medicate with 250 mg tylosin per gallon in drinking water for 3 to 10 days, followed by 40 to 100 g of tylosin per ton of complete feed (Type C medicated feed manufactured from tylosin phosphate Type A medicated article) for 2 to 6 weeks. Swine must consume enough medicated water to provide a therapeutic dose.

Limitations

Only medicated water (250 mg tylosin per gallon) should be available while medicating with BiloVet. Swine must not be slaughtered for food within 48 hours after treatment.

Honey Bees
Indication
For the control of American Foulbrood (Paenibacillus larvae).
Dosage
Mix 200 milligrams tylosin in 20 grams confectioners/powdered sugar. Use immediately. Apply (dust) this mixture over the top bars of the brood chamber once weekly for 3 weeks.
Limitations

The drug should be fed early in the spring or fall and consumed by the bees before the main honey flow begins, to avoid contamination of production honey. Complete treatments at least 4 weeks prior to main honey flow.

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied • Beef And Non-Lactating Dairy
Composition / specifications
200 mg/mL
Swine
Indication
Treatment of swine arthritis caused by Mycoplasma hyosynoviae; swine pneumonia caused by Pasteurella spp.; swine erysipelas caused by Erysipelothrix rhusiopathiae; and swine dysentery associated with Treponema hyodysenteriae when followed by appropriate medication in the drinking water and/or feed.
Dosage
Administer 4 mg per pound of body weight (1 mL per 50 pounds) by intramuscular injection twice daily for not more than 3 consecutive days. Continue treatment 24 hours after symptoms disappear. If tylosin medicated drinking water is used as a follow-up treatment for swine dysentery, the animal should thereafter receive feed containing 40 to 100 grams of tylosin per ton for 2 weeks to assure depletion of tissue residues.
Limitations
Do not inject more than 5 mL per site. Adverse reactions, including shock and death may result from overdosage in baby pigs. It is recommended that tylosin 50 mg/mL injection be used in pigs weighing less than 25 lbs. Swine intended for human consumption must not be slaughtered within 14 days of the last use of this drug product.
Cattle (Beef and Non-lactating Dairy)
Indication
Treatment of bovine respiratory complex (shipping fever, pneumonia) usually associated with Pasteurella multocida and Arcanobacterium pyogenes; foot rot (necrotic pododermatitis), calf diphtheria caused by Fusobacterium necrophorum and metritis caused by Arcanobacterium pyogenes.
Dosage
Administer 8 mg per pound of body weight (1 mL per 25 pounds) by intramuscular injection once daily.
Limitations
Do not inject more than 10 mL per site. Use a 50 mg/mL solution for calves weighing less than 200 pounds. Cattle intended for human consumption must not be slaughtered within 21 days of the last use of this drug product. This drug is not approved for use in female dairy cattle 20 months of age or older, including dry dairy cows. Use in these cattle may cause drug residues in milk and/or in calves born to these cows. This product is not approved for use in calves intended to be processed for veal. A withdrawal period has not been established in pre-ruminating calves.

FDA page: Open in Animal Drugs @ FDA

Species: Honey Bees • No use class stated or implied • Broilers • Not laying eggs for human consumption • Replacements • Excluding turkeys producing eggs for human consumption
Composition / specifications
Each gram contains 1 g tylosin tartrate powder.
Chickens
Indication

For control of mortality caused by necrotic enteritis (NE) associated with Clostridium perfringens in broiler chickens.

Dosage

851 to 1,419 mg/gallon (225 to 375 ppm) in drinking water. Administer medicated drinking water for a single five day period in broiler chickens. To assure all birds receive the intended medication, only medicated water should be available.

Limitations
Indication

As an aid in the treatment of chronic respiratory disease (CRD) associated with Mycoplasma gallisepticum in broiler and replacement chickens. For the control of CRD associated with Mycoplasma gallisepticum at the time of vaccination or other stress in chickens. For the control of CRD associated with Mycoplasma synoviae in broiler chickens.

Dosage

2,000 mg/gallon (528 ppm) in drinking water. Administer medicated drinking water for three days; however, medicated water may be administered for one to five days depending upon severity of infection. Treated chickens must consume enough medicated water to provide 50 mg per pound of body weight per day. Only medicated water should be available to the birds.

Limitations
Turkeys
Indication

For the reduction in severity of effects of infectious sinusitis associated with Mycoplasma gallisepticum.

Dosage

200 mg/gallon (528 ppm) in drinking water.

Limitations
Swine
Indication

For the treatment and control of swine dysentery (SD) associated with Brachyspira hyodysenteriae. For the treatment and control of SD associated with Brachyspira hyodysenteriae when followed immediately by Tylovet Type A medicated article in feed. For the control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis when followed immediately by Tylovet Type A medicated article in feed.

Dosage

250 mg/gallon (66 ppm) in drinking water. 

Swine dysentery: Administer medicated drinking water for 3 to 10 days, depending upon severity of infection. Alternatively, administer medicated drinking water for 3 to 10 days, followed by 40 to 100 g tylosin per ton of complete feed (Type C medicated feed manufactured from Tylovet Type A medicated article) for 2 to 6 weeks. Only medicated water should be available to swine while medicating with Tylovet Soluble.

Porcine proliferative enteropathies: Administer medicated drinking water for 3 to 10 days, followed by 40 to 100 g of tylosin per ton of complete feed (Type C medicated feed manufactured from Tylovet A medicated article) for 2 to 6 weeks. Only medicated water should be available to swine while medicating with Tylovet Soluble.

Limitations
Honey bees
Indication

For the control of American Foulbrood (Paenibacillus larvae).

Dosage

200 mg/colony in confectioners/powdered sugar. Administer three treatments of medicated confectioners sugar once weekly for 3 weeks. The 200 mg dose is applied (dusted) over the top bars of the brood chamber.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied • Beef
Composition / specifications
40 grams of tylosin per lb.
Beef cattle
Indication

For reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterioum pyogenes.

Dosage

8 to 10 g/ton of tylosin (0.08 to 0.10 lbs of Tylovet 100) to be fed so that each animal receives not more than 90 mg per head per day and not less than 60 mg per head per day. Feed continuously as the sole ration.

Limitations
Swine
Indication

For reduction in severity of effects of atrophic rhinitis.

Dosage

Feed 100 g of tylosin per ton (1.0 pound Tylovet 100 per ton) of complete feed. Feed continuously as the sole ration.

Limitations
Indication

For control of swine dysentery.

Dosage

Feed 100 g of tylosin per ton (1.0 pound Tylovet 100 per ton) of complete feed for at least three weeks. Follow with 40 g tylosin per ton (0.4 pound Tylovet 100 per ton) of complete feed until pigs reach market weight.

Limitations
Indication

For the treatment and control of swine dysentery.

Dosage

Feed 40 to 100 g of tylosin (0.4 to 1.0 pounds of Tylovet 100) per ton of complete feed for 2 to 6 weeks immediately after medicating with 250 mg tylosin (as Tylovet Soluble) per gallon in drinking water for 3 to 10 days.

Limitations
Indication

For control of porcine proliferative enteropathies (PPE, ileitis).

Dosage

Feed 100 g of tylosin per ton (1.0 pound Tylovet 100 per ton) of complete feed for 21 days. Alternatively, feed 100 g of tylosin per ton (1.0 pound Tylovet 100 per ton) of complete feed for at least three weeks, followed by 40 g tylosin per ton of complete feed until pigs reach market weight. Alternatively, feed 40 to 100 grams of tylosin (0.4 to 1.0 pounds of Tylovet 100) per ton of complete feed for 2 to 6 weeks immediately after medicating with 250 mg tylosin (as Tylovet Soluble) per gallon in drinking water for 3 to 10 days. Feed continuously as the sole ration when feeding Tylovet.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Fed in confinement for slaughter
Composition / specifications
Type A medicated article containing 20, 30, 45, 60, 80, or 90.7 grams of monensin per pound. Type A medicated article containing 40 or 100 grams of tylosin (as tylosin phosphate) per pound.
Cattle fed in confinement for slaughter
Indication

For improved feed efficiency and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes.

Dosage
Monensin, 5 to 40 grams per ton of feed, plus tylosin 8 to 10 grams per ton of feed.
Limitations

Feed only to cattle being fed in confinement for slaughter. Feed continuously as sole ration to provide 50 to 480 monensin mg/hd/day and 60 to 90 tylosin mg/hd/day. No additional improvement in feed efficiency has been shown from feeding monensin at levels greater than 30 g/ton (360 mg monensin per head per day).

Indication

For prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes.

Dosage
Monensin, 10 to 40 grams per ton plus tylosin, 8 to 10 grams per ton of feed.
Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Fed in confinement for slaughter
Composition / specifications
Monovet®: 90.7 g/lb of monensin; Tylan™: 40 g/lb and 100 g/lb of tylosin
Cattle fed in confinement for slaughter
Indication

For improved feed efficiency and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter.

Dosage

5 to 40 g/ton of Monovet® and 8 to 10 g/ton of Tylan™. Feed continuously as sole ration to provide 50 to 480 mg/hd/day monensin and 60 to 90 mg/hd/day tylosin. No additional improvement in feed efficiency has been shown from feeding monensin at levels greater than 30 g/ton (360 mg monensin per head per day).

Limitations
Indication

For prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter.

Dosage

10 to 40 g/ton of Monovet® and 8 to 10 g/ton of Tylan™. Feed continuously as sole ration to provide 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day and 60 to 90 mg/hd/day tylosin.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Fed in confinement for slaughter
Composition / specifications
Monovet®: 90.7 g/lb of monensin; Tylovet®: 40 g/lb and 100 g/lb of tylosin
Cattle fed in confinement for slaughter
Indication

For improved feed efficiency and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter.

Dosage

5 to 40 g/ton of Monovet® and 8 to 10 g/ton of Tylovet®. Feed continuously as sole ration to provide 50 to 480 mg/hd/day monensin and 60 to 90 mg/hd/day tylosin. No additional improvement in feed efficiency has been shown from feeding monensin at levels greater than 30 g/ton (360 mg monensin per head per day).

Limitations
Indication

For prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter.

Dosage

10 to 40 g/ton of Monovet® and 8 to 10 g/ton of Tylovet®. Feed continuously as sole ration to provide 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day and 60 to 90 mg/hd/day tylosin. 

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Heifers fed in confinement for slaughter
Composition / specifications
CycleGuard®: 500 mg/lb of melengestrol acetate; Monovet®: 90.7 g/lb of monensin; Tylovet®: 40 g/lb and 100 g/lb of tylosin
Heifers fed in confinement for slaughter
Indication

For increased rate of weight gain, improved feed efficiency and suppression of estrus (heat).

Dosage

0.25 to 2 g/ton fed at a rate of 0.5 to 2.0 lb/head/day to provide 0.25 to 0.5 mg/head/day of melengestrol acetate (as CycleGuard®). Feed continuously as sole ration.

Limitations
Indication

For improved feed efficiency and prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii.

Dosage

10 to 40 g/ton to provide 0.14 to 0.42 mg/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/head/day, of monensin (as Monovet®). Feed continuously as sole ration.

Limitations
Indication

For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium pyogenes.

Dosage

8 to 10 g/ton to provide 60 to 90 mg/head/day of tylosin (as Tylovet®). Feed continuously as sole ration.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Heifers fed in confinement for slaughter
Composition / specifications
Optigrid®: 45.4 g/lb (100 g/kg) of ractopamine hydrochloride; Monovet®: 90.7 g/lb of monensin; Tylovet®: 40 g/lb and 100 g/lb of tylosin; CycleGuard®: 500 mg/lb of melengestrol acetate
Heifers fed in confinement for slaughter
Indication

For increased rate of weight gain, improved feed efficiency and increased carcass leanness.

Dosage

9.8 to 24.6 g/ton to provide 90 to 430 mg/head/day of ractopamine hydrochloride (as Optigrid®). Feed continuously as sole ration for the final 28 to 42 days on feed.

Limitations
Indication

For improved feed efficiency and for the prevention and control of coccidiosis due to Eimeria bovis and E. zuernii.

Dosage

10 to 40 g/ton to provide 0.14 to 0.42 mg/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/head/day, of monensin (as Monovet®). Feed continuously as sole ration for the final 28 to 42 days on feed.

Limitations
Indication

For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes.

Dosage

8 to 10 g/ton to provide 60 to 90 mg/head/day of tylosin phosphate (as Tylovet®). Feed continuously as sole ration for the final 28 to 42 days on feed.

Limitations
Indication

For increased rate of weight gain, improved feed efficiency and suppression of estrus (heat).

Dosage

0.125 to 1.0 mg/lb fed at the rate of 0.5 to 2.0 lb/head/day to provide 0.25 to 0.5 mg/head/day of melengestrol acetate (as CycleGuard®). Feed continuously as sole ration for the final 28 to 42 days on feed.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Fed in confinement for slaughter
Composition / specifications
Optigrid®: 45.4 g/lb (100 g/kg) of ractopamine hydrochloride; Monovet®: 90.7 g/lb of monensin; Tylovet®: 40 g/lb and 100 g/lb of tylosin
Cattle fed in confinement for slaughter
Indication

For increased rate of weight gain and improved feed efficiency.

Dosage

8.2 to 24.6 g/ton to provide 70 to 430 mg/head/day of ractopamine hydrochloride (as Optigrid®). Feed continuously as sole ration for the last 28 to 42 days on feed.

Limitations
Indication

For improved feed efficiency and for the prevention and control of coccidiosis due to Eimeria bovis and E. zuernii.

Dosage

10 to 40 g/ton to provide 0.14 to 0.42 mg/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/head/day, of monensin (as Monovet®). Feed continuously as sole ration for the last 28 to 42 days on feed.

Limitations
Indication

For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes.

Dosage

8 to 10 g/ton to provide 60 to 90 mg/head/day of tylosin phosphate (as Tylovet®). Feed continuously as sole ration for the last 28 to 42 days on feed.

Limitations
Indication

For increased rate of weight gain, improved feed efficiency, and increased carcass leanness.

Dosage

9.8 to 24.6 g/ton to provide 90 to 430 mg/head/day of ractopamine hydrochloride (as Optigrid®). Feed continuously as sole ration for the last 28 to 42 days on feed.

Limitations
Indication

For increased rate of weight gain and improved feed efficiency.

Dosage

Not to exceed 800 g/ton feeding a minimum of 1.0 lb/head/day to provide 70 to 400 mg/head/day of ractopamine hydrochloride (as Optigrid®). Feed continuously for the last 28 to 42 days on feed.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Heifers fed in confinement for slaughter
Composition / specifications
Optigrid®: 45.4 g/lb (100 g/kg) of ractopamine hydrochloride; Monovet®: 90.7 g/lb of monensin; Tylovet®: 40 g/lb and 100 g/lb of tylosin; MGA®: 200 mg/lb and 500 mg/lb of melengestrol acetate
Heifers fed in confinement for slaughter
Indication

For increased rate of weight gain, improved feed efficiency, and increased carcass leanness.

Dosage

9.8 to 24.6 g/ton to provide 90 to 430 mg/head/day of ractopamine hydrochloride (as Optigrid®). Feed continuously as sole ration for the final 28 to 42 days on feed.

Limitations
Indication

For increased rate of weight gain, improved feed efficiency and suppression of estrus (heat).

Dosage

0.125 to 1.0 mg/lb fed at the rate of 0.5 to 2.0 lb/head/day (specify one level) to provide 0.25 to 0.5 mg/head/day (specify one level) of melengestrol acetate (as MGA®). Feed continuously as sole ration for the final 28 to 42 days on feed. 

Limitations
Indication

For improved feed efficiency and for the prevention and control of coccidiosis due to Eimeria bovis and E.zuernii.

Dosage

10 to 40 g/ton to provide 0.14 to 0.42 mg/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480mg/head/day, of monensin (as Monovet®). Feed continuously as sole ration for the final 28 to 42 days on feed.

Limitations
Indication

For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes.

Dosage

8 to 10 g/ton to provide 60 to 90 mg/head/day of tylosin phosphate (as Tylovet®). Feed continuously as sole ration for the final 28 to 42 days on feed.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied
Composition / specifications
Type A medicated articles containing both tylosin 5 g/lb and sulfamethazine 5 g/lb.
Swine
Indication

For reduction in the severity of effects of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery associated with Brachyspira hyodysenteriae; control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Arcanobacterium pyogenes); and reducing the incidence of cervical lymphadenitis (jowl abscesses) caused by Group E Streptococci. Only the sulfamethazine portion of this combination is active in controlling jowl abscesses.

Dosage

Tylosin phosphate (100 g/ton) plus sulfamethazine (100 g/ton).

Limitations

Withdraw 15 days before swine are slaughtered.

FDA page: Open in Animal Drugs @ FDA

Species: Heifers fed in confinement for slaughter
Composition / specifications
MGA®: 200 mg/lb and 500 mg/lb of melengestrol acetate; Monovet®: 90.7 g/lb of monensin; Tylan™: 40 g/lb and 100 g/lb of tylosin
Heifers fed in confinement for slaughter
Indication

Increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium pyogenes in heifers fed in confinement for slaughter.

Dosage

0.25 to 2 g/ton (0.0000276 to 0.00022%) of MGA®, 10 to 40 g/ton of Monovet®, and 8 to 10 g/ton of Tylan™. Feed continuously as sole ration to heifers at a rate of 0.5 to 2.0 pounds per head per day to provide 0.25 to 0.5 mg/head/day melengestrol acetate and 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/head/day and 60 to 90 mg/head/day tylosin. The melengestrol acetate portion of this Type C medicated feed must be mixed into the complete feed containing 10 to 40 g/ton monensin and 8 to 10 g/ton tylosin at feeding into the amount of complete feed consumed by an animal per day.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Heifers fed in confinement for slaughter
Composition / specifications
MGA®: 200 mg/lb and 500 mg/lb of melengestrol acetate; Monovet®: 90.7 g/lb of monensin; Tylovet®: 40 g/lb and 100 g/lb of tylosin;
Heifers fed in confinement for slaughter
Indication

Increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium pyogenes in heifers fed in confinement for slaughter.

Dosage

0.25 to 2 g/ton (0.0000276 to 0.00022%) of MGA®, 10 to 40 g/ton of Monovet®, and 8 to 10 g/ton of Tylovet®. Feed continuously as sole ration to heifers at a rate of 0.5 to 2.0 pounds per head per day to provide 0.25 to 0.5 mg/head/day melengestrol acetate and 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/head/day and 60 to 90 mg/head/day tylosin. The melengestrol acetate portion of this Type C medicated feed must be mixed into the complete feed containing 10 to 40 g/ton monensin and 8 to 10 g/ton tylosin at feeding into the amount of complete feed consumed by an animal per day.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Cattle, Heifers Fed In Confinement For Slaughter
Composition / specifications
Dry Type A medicated articles containing 100 or 200 milligrams per pound or liquid Type A article containing 500 milligrams per pound
Cattle (heifers)
Indication

For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), and reduced incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes.

Dosage

Melengestrol acetate, 0.25 to 0.50 milligram per head per day, plus lasalocid (as lasalocid sodium), 100 to 360 milligrams per head per day, and tylosin (as tylosin phosphate), 90 milligrams per head per day. To attain this amount:Add 0.5 to 2.0 pounds per head per day of a liquid or dry medicated feed containing 0.125 to 1.0 milligram of melengestrol acetate per pound to a medicated feed containing 10 to 30 grams of lasalocid and 8 to 10 grams of tylosin per ton; or Add 0.5 to 2.0 pounds per head per day of a liquid or dry medicated feed containing 0.125 to 1.0 milligram of melengestrol acetate per pound plus 50 to 720 milligrams of lasalocid per pound to 8 to 10 grams of tylosin per ton.

Limitations

For heifers being fed in confinement for slaughter. 
Not effective in steers and spayed heifers.

This combination may only be marketed as a pelleted product.

Do not allow horses or other equines access to premixes or supplements containing lasalocid, as ingestion may be fatal. The safety of lasalocid in unapproved species has not been established. Mixing errors resulting in excessive concentrations of lasalocid could be fatal to cattle and sheep.

Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Heifers fed in confinement for slaughter
Composition / specifications
Actogain™: 45.4 g/lb (100 g/kg) of ractopamine hydrochloride, Monovet®: 90.7 g/lb of monensin, Tylan™: 40 g/lb and 100 g/lb of tylosin, and MGA®: 200 mg/lb and 500 mg/lb of melengestrol acetate
Heifers fed in confinement for slaughter
Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

9.8 to 24.6 g/ton of Actogain™, 10 to 40 g/ton of Monovet®, and 8 to 10 g/ton of Tylan™. Feed continuously as sole ration to provide 90 to 430 mg/hd/day ractopamine and 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day and 60 to 90 mg/hd/day tylosin for the last 28 to 42 days on feed.

Limitations
Indication

For increased rate of weight gain, improved feed efficiency and suppression of estrus (heat).

Dosage

0.125 to 1.0 mg/lb of MGA® for increased rate of weight gain, improved feed efficiency and suppression of estrus (heat) in heifers fed in confinement for slaughter. Must be top dressed or mixed with a complete ration containing monensin (10 to 40 g/ton), tylosin (8 to 10 g/ton) and ractopamine (9.8 to 24.6 g/ton). Feed at the rate of 0.5-2.0 pound(s) per head per day (specify one level) to provide 0.25-0.5 mg melengestrol acetate per head per day (specify one level). Feed melengestrol acetate in this combination for the final 28 to 42 days on feed.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Heifers fed in confinement for slaughter
Composition / specifications
Actogain™: 45.4 g/lb (100 g/kg) of ractopamine hydrochloride, Monovet®: 90.7 g/lb of monensin, Tylovet®: 40 g/lb and 100 g/lb of tylosin, and
Heifers fed in confinement for slaughter
Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

9.8 to 24.6 g/ton of Actogain™, 10 to 40 g/ton of Monovet®, and 8 to 10 g/ton of Tylovet®. Feed continuously as sole ration to provide 90 to 430 mg/hd/day ractopamine and 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day and 60 to 90 mg/hd/day tylosin for the last 28 to 42 days on feed.

Limitations
Indication

For increased rate of weight gain, improved feed efficiency and suppression of estrus (heat).

Dosage

0.125 to 1.0 mg/lb of MGA®. Must be top dressed or mixed with a complete ration containing monensin (10 to 40 g/ton), tylosin (8 to 10 g/ton) and ractopamine (9.8 to 24.6 g/ton). Feed at the rate of 0.5-2.0 pound(s) per head per day (specify one level) to provide 0.25-0.5 mg melengestrol acetate per head per day (specify one level). Feed melengestrol acetate in this combination for the final 28 to 42 days on feed.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Fed in confinement for slaughter
Composition / specifications
Deccox®: 6% (27.2 g/lb) of decoquinate; Monovet®: 90.7 g/lb of monensin; Tylan™: 40 g/lb and 100 g/lb of tylosin
Cattle fed in confinement for slaughter
Indication

For the prevention of coccidiosis caused by Eimeria bovis and E. zuernii, for improved feed efficiency, and for reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in cattle fed in confinement for slaughter.

Dosage

13.6 to 27.2 g/ton of Deccox®, 5 to 30 g/ton of Monovet®, and 8 to 10 g/ton of Tylan™. Feed only to cattle being fed in confinement for slaughter. Feed continuously as the sole ration to provide 22.7 mg of decoquinate per 100 lb. of body weight per day, 50 to 360 mg of monensin per head per day, and 60 to 90 mg tylosin per head per day as monensin sodium and as tylosin phosphate. Feed for at least 28 days during periods of exposure to coccidiosis or when it is likely to be a hazard.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Fed in confinement for slaughter
Composition / specifications
Deccox®: 6% (27.2 g/lb) of decoquinate; Monovet®: 90.7 g/lb of monensin; Tylovet®: 40 g/lb and 100 g/lb of tylosin
Cattle fed in confinement for slaughter
Indication

For the prevention of coccidiosis caused by Eimeria bovis and E. zuernii, for improved feed efficiency, and for reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in cattle fed in confinement for slaughter.

Dosage

13.6 to 27.2 g/ton of Deccox®, 5 to 30 g/ton of Monovet®, and 8 to 10 g/ton of Tylovet®. Feed only to cattle being fed in confinement for slaughter. Feed continuously as the sole ration to provide 22.7 mg of decoquinate per 100 lb. of body weight per day, 50 to 360 mg of monensin per head per day, and 60 to 90 mg tylosin per head per day as monensin sodium and as tylosin phosphate. Feed for at least 28 days during periods of exposure to coccidiosis or when it is likely to be a hazard.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Heifers fed in confinement for slaughter
Composition / specifications
Optaflexx™: 45.4 g/lb (100 g/kg) of ractopamine hydrochloride, Monovet®: 90.7 g/lb of monensin, Tylan™: 40 g/lb and 100 g/lb of tylosin, and MGA®: 200 mg/lb and 500 mg/lb of melengestrol acetate
Heifers fed in confinement for slaughter
Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

9.8 to 24.6 g/ton of Optaflexx™, 10 to 40 g/ton of Monovet®, and 8 to 10 g/ton of Tylan™. Feed continuously as sole ration to provide 90 to 430 mg/hd/day ractopamine and 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day and 60 to 90 mg/hd/day tylosin for the last 28 to 42 days on feed.

Limitations
Indication

For increased rate of weight gain, improved feed efficiency and suppression of estrus (heat).

Dosage

0.125 to 1.0 mg/lb of MGA® for increased rate of weight gain, improved feed efficiency and suppression of estrus (heat) in heifers fed in confinement for slaughter. Must be top dressed or mixed with a complete ration containing monensin (10 to 40 g/ton), tylosin (8 to 10 g/ton) and ractopamine (9.8 to 24.6 g/ton). Feed at the rate of 0.5-2.0 pound(s) per head per day (specify one level) to provide 0.25-0.5 mg melengestrol acetate per head per day (specify one level). Feed melengestrol acetate in this combination for the final 28 to 42 days on feed.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Heifers fed in confinement for slaughter
Composition / specifications
Optaflexx™: 45.4 g/lb (100 g/kg) of ractopamine hydrochloride, Monovet®: 90.7 g/lb of monensin, Tylovet®: 40 g/lb and 100 g/lb of tylosin, and MGA®: 200 mg/lb and 500 mg/lb of melengestrol acetate
Heifers fed in confinement for slaughter
Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

9.8 to 24.6 g/ton of Optaflexx™, 10 to 40 g/ton of Monovet®, and 8 to 10 g/ton of Tylovet®. Feed continuously as sole ration to provide 90 to 430 mg/hd/day ractopamine and 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day and 60 to 90 mg/hd/day tylosin for the last 28 to 42 days on feed.

Limitations
Indication

For increased rate of weight gain, improved feed efficiency and suppression of estrus (heat).

Dosage

0.125 to 1.0 mg/lb of MGA®. Must be top dressed or mixed with a complete ration containing monensin (10 to 40 g/ton), tylosin (8 to 10 g/ton) and ractopamine (9.8 to 24.6 g/ton). Feed at the rate of 0.5-2.0 pound(s) per head per day (specify one level) to provide 0.25-0.5 mg melengestrol acetate per head per day (specify one level). Feed melengestrol acetate in this combination for the final 28 to 42 days on feed.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Fed in confinement for slaughter
Composition / specifications
Actogain™: 45.4 g/lb (100 g/kg) of ractopamine hydrochloride, Monovet®: 90.7 g/lb of monensin, and Tylan™: 40 g/lb and 100 g/lb of tylosin
Cattle fed in confinement for slaughter
Indication

For increased rate of weight gain and improved feed efficiency in cattle fed in confinement for slaughter during the last 28 to 42 days on feed.

Dosage

Not to exceed 800 g/ton Actogain™.Feed a minimum of 1.0 lb/hd/day Ractopamine Type C Top Dress TD + MT continuously to cattle fed in confinement for slaughter, to provide 70 to 400 mg/head/day ractopamine for the last 28 to 42 days on feed. Feed on top of a ration containing 10 to 40 g/ton monensin and 8 to 10 g/ton tylosin phosphate, to provide 0.14 to 0.42 mg monensin/lb body weight/day, depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day and 60 to 90 mg/hd/day tylosin.

Limitations
Indication

For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

8.2 to 24.6 g/ton of Actogain™, 10 to 40 g/ton of Monovet®, and 8 to 10 g/ton of Tylan™. Feed continuously as sole ration to provide 70 to 430 mg/hd/day ractopamine and 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day and 60 to 90 mg/hd/day tylosin for the last 28 to 42 days on feed.

Limitations
Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

9.8 to 24.6 g/ton Actogain™, 10 to 40 g/ton Monovet®, and 8 to 10 g/ton Tylan™. Feed continuously as sole ration to provide 90 to 430 mg/hd/day ractopamine and 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day and 60 to 90 mg/hd/day tylosin for the last 28 to 42 days on feed.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Fed in confinement for slaughter
Composition / specifications
Optaflexx™: 45.4 g/lb (100 g/kg) of ractopamine hydrochloride, Monovet®: 90.7 g/lb of monensin, and Tylan™: 40 g/lb and 100g/lb of tylosin
Cattle fed in confinement for slaughter
Indication

For increased rate of weight gain and improved feed efficiency in cattle fed in confinement for slaughter during the last 28 to 42 days on feed.

Dosage

Not to exceed 800 g/ton Optaflexx™. Feed a minimum of 1.0 lb/hd/day Ractopamine Type C Top Dress TD + MT
continuously to cattle fed in confinement for slaughter, to provide 70 to 400 mg/head/day ractopamine for the last 28 to 42 days on feed. Feed on top of a ration containing 10 to 40 g/ton monensin and 8 to 10 g/ton tylosin
phosphate, to provide 0.14 to 0.42 mg monensin/lb body weight/day, depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day and 60 to 90 mg/hd/day tylosin.

Limitations
Indication

For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of
incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for
slaughter for the last 28 to 42 days on feed.

Dosage

8.2 to 24.6 g/ton of Optaflexx™, 10 to 40 g/ton of Monovet®, and 8 to 10 g/ton of Tylan™. Feed continuously as sole ration to provide 70 to 430 mg/hd/day ractopamine and 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day and 60 to 90
mg/hd/day tylosin for the last 28 to 42 days on feed.

Limitations
Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E.
zuernii
and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in
confinement for slaughter for the last 28 to 42 days on feed.

Dosage

9.8 to 24.6 g/ton Optaflexx™, 10 to 40 g/ton Monovet®, and 8 to 10 g/ton Tylan™. Feed continuously as sole ration to provide 90 to 430 mg/hd/day ractopamine
and 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day and 60 to 90 mg/hd/day tylosin for the last 28 to 42 days on feed.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Fed in confinement for slaughter
Composition / specifications
Actogain™: 45.4 g/lb (100 g/kg) of ractopamine hydrochloride, Monovet®: 90.7 g/lb of monensin, and Tylovet®: 40 g/lb and 100 g/lb of tylosin
Cattle fed in confinement for slaughter
Indication

For increased rate of weight gain and improved feed efficiency in cattle fed in confinement for slaughter during the last 28 to 42 days on feed.

Dosage

Not to exceed 800 g/ton Actogain™. Feed a minimum of 1.0 lb/hd/day Ractopamine Type C Top Dress TD + MT continuously to cattle fed in confinement for slaughter, to provide 70 to 400 mg/head/day ractopamine for the last 28 to 42 days on feed. Feed on top of a ration containing 10 to 40 g/ton monensin and 8 to 10 g/ton tylosin phosphate, to provide 0.14 to 0.42 mg monensin/lb body weight/day, depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day and 60 to 90 mg/hd/day tylosin.

Limitations
Indication

For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

8.2 to 24.6 g/ton of Actogain™, 10 to 40 g/ton of Monovet®, and 8 to 10 g/ton of Tylovet®. Feed continuously as sole ration to provide 70 to 430 mg/hd/day ractopamine and 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day and 60 to 90 mg/hd/day tylosin for the last 28 to 42 days on feed.

Limitations
Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

9.8 to 24.6 g/ton Actogain™, 10 to 40 g/ton Monovet®, and 8 to 10 g/ton Tylovet®. Feed continuously as sole ration to provide 90 to 430 mg/hd/day ractopamine and 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day and 60 to 90 mg/hd/day tylosin for the last 28 to 42 days on feed.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Fed in confinement for slaughter
Composition / specifications
Optaflexx™: 45.4 g/lb (100 g/kg) of ractopamine hydrochloride; Monovet®: 90.7 g/lb of monensin; Tylovet®: 40 g/lb and 100 g/lb of tylosin
Cattle fed in confinement for slaughter
Indication

For increased rate of weight gain and improved feed efficiency in cattle fed in confinement for slaughter during the last 28 to 42 days on feed.

Dosage

Not to exceed 800 g/ton Optaflexx™. Feed a minimum of 1.0 lb/hd/day Ractopamine Type C Top Dress TD + MT continuously to cattle fed in confinement for slaughter, to provide 70 to 400 mg/head/day ractopamine for the last 28 to 42 days on feed. Feed on top of a ration containing 10 to 40 g/ton monensin and 8 to 10 g/ton tylosin phosphate, to provide 0.14 to 0.42 mg monensin/lb body weight/day, depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day and 60 to 90 mg/hd/day tylosin.

Limitations
Indication

For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

8.2 to 24.6 g/ton of Optaflexx™, 10 to 40 g/ton of Monovet®, and 8 to 10 g/ton of Tylovet®. Feed continuously as sole ration to provide 70 to 430 mg/hd/day ractopamine and 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day and 60 to 90 mg/hd/day tylosin for the last 28 to 42 days on feed.

Limitations
Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

9.8 to 24.6 g/ton Optaflexx™, 10 to 40 g/ton Monovet®, and 8 to 10 g/ton Tylovet®. Feed continuously as sole ration to provide 90 to 430 mg/hd/day ractopamine and 0.14 to 0.42 mg monensin/lb body weight per day, depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day and 60 to 90 mg/hd/day tylosin for the last 28 to 42 days on feed.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Honey Bees • No use class stated or implied • Broilers • Not laying eggs for human consumption • Replacements • Excluding turkeys producing eggs for human consumption
Composition / specifications
Tylosin (as tylosin tartrate) :100 g
Turkeys
Indication
For the reduction in severity of effects of infectious sinusitis associated with Mycoplasma gallisepticum.
Dosage
2,000 mg/gallon (528 ppm) in drinking water.
Limitations
Only medicated water should be available to the birds.
Swine
Indication
For the treatment and control of swine dysentery (SD) associated with Brachyspira hyodysenteriae. For the treatment and control of SD associated with Brachyspira hyodysenteriae when followed immediately by Tylan Type A medicated article in feed. For the control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis when followed immediately by Tylan Type A medicated article in feed.
Dosage
250 mg/gallon (66 ppm) in drinking water.
Limitations
Only medicated water should be available to swine while medicating with Tylan Soluble.
Chickens
Indication
For the control of mortality caused by necrotic enteritis (NE) associated with Clostridium perfringens in broiler chickens.
Dosage
851 to 1,419 mg/gallon (225 to 375 ppm) in drinking water.
Limitations
Only medicated water should be available to the birds.
Indication
As an aid in the treatment of chronic respiratory disease (CRD) associated with Mycoplasma gallisepticum in broiler andreplacement chickens. For the control of CRD associated with Mycoplasma gallisepticum at the time of vaccination or other stress in chickens. For the control of CRD associated with Mycoplasma synoviae in broiler chickens.
Dosage
2,000 mg/gallon (528 ppm) in drinking water.
Limitations
Only medicated water should be available to the birds.
Honey Bees
Indication
For the control of American Foulbrood (Paenibacillus larvae).
Dosage
200 mg/colony in confectioners/powdered sugar.
Limitations

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Species: Swine, Starting • Swine, Growing • Swine, Finishing
Composition / specifications
Tylosin is the antibiotic substance produced by growth of Streptomyces fradiae or the same antibiotic substance produced by any other means. Tylosin present as the phosphate salt, conforms to the appropriate antibiotic standard. Type A medicated article levels of tylosin: 10 grams per pound
Swine
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3- 10 days, 40- 100 grams per ton in feed for 2- 6 weeks.
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
As tylosin phosphate.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
As tylosin phosphate.
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10- 100 grams per ton of feed. Pre-starter or starter: 20- 100 grams per ton. Grower: 20- 40 grams per ton. Finisher: 10- 20 grams per ton.
Limitations
As tylosin phosphate. Continuous use.

FDA page: Open in Animal Drugs @ FDA

Species: Broilers
Composition / specifications
Tylosin phosphate – 10, 40, or 100 g/lb
Label highlights
Indication

For increased rate of weight gain and improved feed efficiency, and as an aid in the prevention of coccidiosis caused by Eimeria tenella, E. necatrix, E. acervulina, E. maxima, E. brunetti, and E. mivati in broiler chickens.

Dosage
:

Tylosin phosphate is added to chicken feed at concentrations of 4 to 50 g/ton

Salinomycin sodium is added to chicken feed at concentrations of 40 to 60 g/ton

Limitations

For broiler chickens only. Feed continuously as sole ration. Do not feed to laying hens. Not approved for use with pellet binders. May be fatal if accidentally fed to adult turkeys or horses.

FDA page: Open in Animal Drugs @ FDA

Species: Broilers
Composition / specifications
Tylosin phosphate – 100 g/lb
Label highlights
Indication
For increased rate of weight gain and improved feed efficiency, and as an aid in the prevention of coccidiosis caused by Eimeria tenella, E. necatrix, E. acervulina, E. maxima, E. brunetti, and E. mivati in broiler chickens.

Dosage
:

Tylosin phosphate is added to chicken feed at concentrations of 4 to 50 g/ton.

Salinomycin sodium is added to chicken feed at concentrations of 40 to 60 g/ton.

Limitations

For broiler chickens only. Feed continuously as sole ration. Do not feed to laying hens. Not approved for use with pellet binders. May be fatal if accidentally fed to adult turkeys or horses.

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied
Composition / specifications
Type A medicated articles containing pyrantel tartrate 9.6, 19.2, and 80 grams per pound. Type A medicated articles containing 10, 40, or 100 grams per pound tylosin phosphate.
Swine
Indication

For prevention of swine dysentery (vibrionic); aid in the prevention of migration and establishment of large roundworms (Ascaris suum) infections; and as an aid in the prevention of establishment of nodular worm (Oesophagostomum) infections.

Dosage

96 grams (0.0106 percent) pyrantel tartrate and 40 grams tylosin per ton of Type C medicated feed.

Limitations

Feed continuously as the sole ration until market weight. This feed is for use following the feeding of 100 g per ton tylosin for at least 3 weeks. Do not use in any finished feed (supplement, concentrate or complete feed) containing bentonite. Withdraw 24 hours prior to slaughter.

Indication

For prevention of swine dysentery (vibrionic); aid in the prevention of migration and establishment of large roundworms (Ascaris suum) infections; and as an aid in the prevention of establishment of nodular worm (Oesophagostomum) infections.

Dosage

96 grams (0.0106 percent) pyrantel tartrate and 100 grams tylosin per ton of Type C medicated feed.

Limitations

Feed continuously as the sole ration for at least three weeks, followed by 40 g per ton tylosin and 96 g per ton pyrantel tartrate until pigs reach market weight. Do not use in any finished feed (supplement, concentrate or complete feed) containing bentonite. Withdraw 24 hours prior to slaughter.

Indication

For treatment and control of swine dysentery (vibrionic); immediately after medicating with tylosin in drinking water; aid in the prevention of migration and establishment of large roundworm (Ascaris suum) infections; and as an aid in the prevention of establishment of nodular worm (Oesophagostomum) infections.

Dosage

96 grams (0.0106 percent) pyrantel tartrate and 40 or 100 grams tylosin per ton of Type C medicated feed.

Limitations

Feed 40 or 100 g of tylosin per ton of complete feed continuously as the sole ration for 2 to 6 weeks after treatment with tylosin in drinking water (250 mg tylosin per gallon) for 3 to 10 days. Do not use in any finished feed (supplement, concentrate or complete feed) containing bentonite. Withdraw 24 hours prior to slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Beef heifers fed in confinement for slaughter
Composition / specifications
Liquid Type A article containing 500 milligrams per pound.
Cattle (heifers)
Indication

For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), and reduced incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes.

Dosage

Melengestrol acetate, 0.25 to 0.50 milligram per head per day, plus tylosin (as tylosin phosphate) at 60 to 90 milligrams per head per day. To attain this amount: Add 0.5 to 2.0 pounds per head per day of a liquid or dry medicated feed containing 0.125 to 1.0 milligram of melengestrol acetate per pound to a medicated feed containing 8 to 10 grams of tylosin per ton; Add 0.5 to 2.0 pounds per head per day of a liquid or dry medicated feed containing 0.125 to 1.0 milligram of melengestrol acetate per pound to 4.5 to 18 pounds of a dry medicated feed containing 10 to 40 grams of tylosin per ton; or Add 0.5 to 2.0 lb/head/day of a liquid or dry medicated feed containing 0.125 to 1.0 mg melengestrol acetate plus 45 to 180 mg tylosin/ lb to a ration of nonmedicated feed.

Limitations

Feed continuously as sole ration. MGA is for use only in heifers being fed in confinement for slaughter. Not effective in steers and spayed heifers. When mixing and handling tylosin, use protective clothing, impervious gloves and a dust mask. Operators should wash thoroughly with soap and water after handling. If accidental eye contact occurs, immediately rinse thoroughly with water.

Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Beef heifers fed in confinement for slaughter
Composition / specifications
<p class="Default">Melengestrol acetate &ndash; 200 and 500 g/lb</p>
<p class="Default">Lasalocid sodium &ndash; 68 and 91 g/lb</p>
<p>Tylosin phosphate - 40 and 100 g/lb
Cattle
Indication

For increased rate of weight gain, improved feed efficiency, and suppression of estrus (heat) in heifers fed in confinement for slaughter.

Dosage

Feed 0.25 to 2.0 g/ton melengestrol acetate to heifers at the rate of 0.5 to 2.0 lb/hd/day as a top dress or mixed into a complete feed to provide 0.25 to 0.5 mg melengestrol acetate per head per day and 100 to 1440 g/ton lasalocid to provide 100 to 360 mg lasalocid per head per day. Melengestrol acetate and lasalocid may be fed continuously throughout the time the heifers are being grown and finished for slaughter. May be fed to heifers in combination with a complete feed containing 8 to 10 g of tylosin per ton for reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes.

Limitations

When tylosin is fed in combination with melengestrol acetate and lasalocid, the level of tylosin is limited to 90 mg/hd/day. Melengestrol acetate is only for use in heifers being fed in confinement for slaughter. Not effective in steers and spayed heifers. This combination may only be marketed as a pelleted product. Do not allow horses or other equines access to premixes or supplements containing lasalocid, as ingestion may be fatal. The safety of lasalocid in unapproved species has not been established. Mixing errors resulting in excessive lasalocid concentrations could be fatal to cattle and sheep. When mixing and handling lasalocid, use protective clothing, impervious gloves and a dust mask, avoid contact with eyes. Operators should wash hands thoroughly with soap and water after handling. Use melengestrol acetate only as directed.

Cattle
Indication

For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), and for reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in heifers fed in confinement for slaughter.

Dosage

Feed 0.25 to 2.0 g/ton melengestrol acetate to heifers at the rate of 0.5 to 2.0 lb/hd/day as a top dress or mixed into a complete feed to provide 0.25 to 0.5 mg melengestrol acetate per head lasalocid per day and 100 to 1440 g/ton lasalocid to provide 100 to 360 mg lasalocid per head per day and 90 to 360 g/ton tylosin to provide 90 mg tylosin per head per day. Melengestrol acetate, lasalocid, and tylosin may be fed continuously throughout the time the heifers are being grown and finished for slaughter.

Limitations

When tylosin is fed in combination with melengestrol acetate and lasalocid, the level of tylosin is limited to 90 mg/hd/day. For use only in heifers being fed in confinement for slaughter. Not effective in steers and spayed heifers. This combination may only be marketed as a pelleted product. Do not allow horses or other equines access to premixes or supplements containing lasalocid, as ingestion may be fatal. The safety of lasalocid in unapproved species has not been established. Mixing errors resulting in excessive concentrations of lasalocid could be fatal to cattle and sheep. When mixing and handling lasalocid, use protective clothing, impervious gloves and a dust mask, avoid contact with eyes. Operators should wash hands thoroughly with soap and water after handling. Use melengestrol acetate only as directed.

FDA page: Open in Animal Drugs @ FDA

Species: Beef heifers fed in confinement for slaughter
Composition / specifications
Melengestrol acetate 100 and 200 g/lb (dry) and 500 g/lb (liquid)
Beef heifers fed in confinement for slaughter
Indication

For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), and reduced incidence of liver abscesses caused by Fusobacterium Necrophorum and Arcanobacterium (Actinomyces) pyogenes in heifers fed in confinement for slaughter.

Dosage
Limitations

Feed continuously as sole ration. Melengestrol acetate is for use only in heifers being fed in confinement for slaughter.  Not effective in steers or spayed heifers.  Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Fed in confinement for slaughter
Composition / specifications
Type A medicated article containing 21.77 grams of zilpaterol hydrochloride per pound. Type A medicated article containing 20, 30, 45, 60, 80, or 90.7 grams of monensin per pound. Type A medicated article containing 40 or 100 grams of tylosin (as tylosin phosphate) per pound.
Cattle (fed in confinement for slaughter)
Indication
For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 20 to 40 days on feed.
Dosage

Component Feed: 6.8 to 24 g/ton zilpaterol to provide 60 mg/head/day zilpaterol; 10 to 40 g/ton monensin, to provide 0.14 to 0.42 mg/lb body weight/day monensin, depending on the severity of the coccidiosis challenge, up to 480 mg/head/day monensin; and 8 to 10 g/ton tylosin to provide 60 to 90 mg/head/day tylosin.

Limitations

Feed continuously during the last 20 to 40 days on feed. Do not allow horses or other equines access to feed containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite.Zilpaterol hydrochloride is not for use in animals intended for breeding. Do not allow horses or other equines access to feed containing zilpaterol. Do not use in veal calves. Animals receiving zilpaterol hydrochloride may exhibit increased respiratory rate aswell as elevated levels of creatine phosphokinase (CPK) and creatine.Special considerations:1) Labeling for Type B feeds used to manufacture Type C complete feeds must bear the caution statement: Not to be fed to cattle in excess of 90 mg/head/day in complete feed. If pen consumption of complete feed exceeds 26.5 lb/head/day (90 percent dry matter basis), zilpaterol should not be fed in complete feed.

2) Type B Liquid Feeds can be manufactured containing 68 to 680 g zilpaterol hydrochloride/ton. Inadequate mixing (recirculation or agitation) of monensin liquid Type B or Type C medicated feeds has resulted in increased monensin concentration, which has been fatal to cattle. For liquid feeds stored in recirculating tank systems: Recirculate immediately prior to use for not less than 10 minutes, moving not less than 1 percent of the tank contents per minute from the bottom of the tank to the top. Recirculate daily as described even when not used. For liquid feeds stored in mechanical, air or other agitation-type tank systems: Agitate immediately prior to use for not less than 10 minutes, creating turbulence at the bottom of the tank that is visible at the top. Agitate daily as described even when not used.3) All labeling for Type B and Type C feeds provides the warning: The active ingredient in Zilmax® is zilpaterol hydrochloride, a beta2-adrenergic agonist. Not for use in humans. An anti-dust process has been applied to the drug product, Zilmax®, in order to greatly reduce inhalation risk. Extended handling tasks with the potential for dust generation require respiratory protection. Wear appropriate skin protection (e.g., impervious gloves, apron, overalls), if there is a potential for extended skin contact. Wear protective eyewear, if there is a potential for eye contact. If accidental eye contact occurs, immediately rinse with water and consult a physician.

Indication
For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 20 to 40 days on feed.
Dosage

Complete feed: 6.8 g/ton zilpaterol to provide 60 to 90 mg/head/day zilpaterol; 10 to 40 g/ton monensin, to provide 0.14 to 0.42 mg/lb body weight/day monensin, depending on the severity of the coccidiosis challenge, up to 480 mg/head/day monensin; and 8 to 10 g/ton tylosin to provide 60 to 90 mg/head/day tylosin.

Limitations

Feed continuously as sole ration during the last 20 to 40 days on feed. Do not allow horses or other equines access to feedscontaining monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite.Zilpaterol hydrochloride is not for use in animals intended for breeding. Do not allow horses or other equines access to feed containing zilpaterol. Do not use in veal calves. Not to be fed to cattle in excess of 90 mg/head/day in complete feed. If pen consumption of complete feed exceeds 26.5 lb/head/day (90 percent dry matter basis), zilpaterol should not be fed in complete feed. Animals receiving zilpaterol hydrochloride may exhibit increased respiratory rate as well as elevated levels of creatine phosphokinase (CPK) and creatine.

FDA page: Open in Animal Drugs @ FDA

Species: Fed in confinement for slaughter
Composition / specifications
Type A medicated article containing 45.4 grams of ractopamine hydrochloride per pound. Type A article containing 20, 30, 45, 60, 80, or 90.7 grams of monensin per pound. Type A article containing 40 or 100 grams of tylosin (as tylosin phosphate) per pound.
Cattle fed in confinement for slaughter
Indication

For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

Ractopamine hydrochloride (8.2 to 24.6 g/ton) in combination with monensin (10 to 40 g/ton), and tylosin phosphate (8 to 10 g/ton).

Limitations

Feed continuously as sole ration to provide 70 to 430 mg ractopamine per hd/day and 0.14 to 0.42 mg monensin per lb body weight/day (depending on severity of coccidiosis challenge, up to 480 mg/hd/day), and 60 to 90 mg tylosin per hd/day for the last 28 to 42 days on feed.

Indication

For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, and reduction in incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter during the last 28 to 42 days on feed.

Dosage

Ractopamine hydrochloride top dress (not to exceed 800 g/ton) to be fed with a ration containing 10 to 40 g/ton monensin and 8 to 10 g/ton tylosin phosphate.

Limitations

Feed a minimum of 1.0 lb/hd/day continuously to cattle fed in confinement for slaughter, to provide 70 to 400 mg/head/day ractopamine for the last 28 to 42 days on feed. Feed on top of a ration containing 10 to 40 g/ton monensin and 8 to 10 g/ton tylosin phosphate, to provide 0.14 to 0.42 mg monensin/lb body weight/day (depending on the severity of the coccidiosis challenge, up to 480 mg/hd/day), and 60 to 90 mg/hd/day tylosin.

Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

Ractopamine hydrochloride (9.8 to 24.6 g/ton) in combination with monensin (10 to 40 g/ton) and tylosin phosphate (8 to 10 g/ton).

Limitations

Feed continuously as sole ration to provide 90 to 430 mg ractopamine per hd/day and 0.14 to 0.42 mg monensin per lb body weight/day (depending on severity of coccidiosis challenge, up to 480 mg/hd/day), and 60 to 90 mg tylosin per hd/day for the last 28 to 42 days on feed.

Labeling: The labeling of dry Type B feeds containing ractopamine, monensin, and tylosin intended for use in cattle shall bear the following caution statements:

Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Ractopamine HCl is not for animals intended for breeding.

The labeling of liquid Type B feeds containing ractopamine, monensin and tylosin intended for use in cattle shall bear the following caution statements:

Inadequate mixing (recirculation or agitation) of monensin liquid Type B medicated feed has resulted in increased monensin concentration, which has been fatal to cattle. Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Feeding undiluted or mixing errors resulting in high concentrations of monensin has been fatal to cattle. Must be thoroughly mixed in feeds before use. Do not feed undiluted. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any liquid feed containing sodium metabisulfite or in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Expiration Date: 31 days after the date of manufacture. Ractopamine HCl is not for animals intended for breeding.

The labeling of all Type C feeds containing ractopamine, monensin, and tylosin intended for use in cattle shall bear the following caution statements:

Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite. Ractopamine HCl is not for animals intended for breeding.

FDA page: Open in Animal Drugs @ FDA

Species: Beef heifers fed in confinement for slaughter
Composition / specifications
Type A medicated article containing 45.4 grams of ractopamine hydrochloride per pound. Type A article containing 20, 30, 45, 60, 80, or 90.7 grams of monensin per pound. Type A article containing 40 or 100 grams of tylosin (as tylosin phosphate) per pound. Type A medicated article containing 100 or 200 milligrams of melengestrol acetate per pound or liquid Type A medicated article containing 500 milligrams of melengestrol acetate per pound.
Cattle (heifers fed in confinement for slaughter)
Indication

For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes, and for suppression of estrus (heat) in heifers fed in confinement for slaughter for the last 28 to 42 days on feed.

Dosage

Complete feed: Feed continuously as sole ration containing 9.8 to 24.6 g/ton ractopamine to provide 90 to 430 mg/hd/day ractopamine; 10 to 40 g/ton monensin to provide 0.14 to 0.42 mg monensin/lb of body weight per day, depending on severity of coccidiosis challenge, up to 480 mg/head/day; 8 to 10 g/ton tylosin to provide 60 to 90 mg/head/day tylosin for the last 28 to 42 days on feed. Mix or top dress with medicated feed containing 0.125 to 1.0 mg melengestrol acetate per pound fed at the rate of 0.5 to 2.0 lb/head/day to provide 0.25 to 0.5 mg melengestrol acetate per head per day for the last 28 to 42 days on feed.

Limitations

Melengestrol acetate is not effective in steers and spayed heifers. Withdrawal periods of three to five days should be avoided to prevent the possibility that the heifers may come into estrus (heat) at time of loading. Do not allow horses or other equines access to feeds containing monensin. Ingestion of monensin by horses has been fatal. Monensin medicated cattle feed is safe for use in cattle only. Consumption by unapproved species may result in toxic reactions. Do not exceed the levels of monensin recommended in the feeding directions, as reduced average daily gains may result. If feed refusals containing monensin are fed to other groups of cattle, the concentration of monensin in the refusals and amount of refusals fed should be taken into consideration to prevent monensin overdosing. Do not use in any finished feed (supplement, concentrate or complete feed) containing in excess of 2% bentonite.

Ractopamine HCl is not for animals intended for breeding.Special considerations:Mixing directions for liquid melengestrol acetate Type C feeds stored in recirculation tank systems, labeling indicates: “Recirculate immediately prior to use for no less than 10 minutes, moving not less than 1 percent of the tank contents from the bottom of the tank to the top. Recirculate daily, as directed in this paragraph even when the Type C feed is not used.” For liquid melengestrol Type C feeds stored in mechanical, air or other agitation-type tank systems: “Agitate immediately prior to use for not less than 10 minutes, creating a turbulence at the bottom of the tank that is visible at the top. Agitate daily, as directed in this paragraph, even when the Type C feed is not used.”

FDA page: Open in Animal Drugs @ FDA

Species: Broilers
Composition / specifications
Tylosin phosphate- 4 to 50 g/ton</p>
<p>Salinomycin sodium- 40 to 60 g/ton
Label highlights
Indication
For increased rate of weight gain and improved feed efficiency, and as an aid in the prevention of coccidiosis caused by Eimeria tenella, E. necatrix, E. acervulina, E. maxima, E. brunetti, and E. mivati in broiler chickens
Dosage
Tylosin phosphate is added to chicken feed at concentrations of 4 to 50 g/ton for increased rate of weight gain and improved feed efficiency in broiler chickens.

Salinomycin sodium is added to chicken feed at concentrations of 40 to 60 g/ton for the prevention of coccidiosis caused by Eimeria tenella, E. necatrix, E. acervulina, E. maxima, E. brunetti, and E. mivati in broiler chickens

Limitations
Feed continuously as sole ration. For broiler chickens only. Do not feed to laying hens. Not approved for use with pellet binders. May be fatal if accidentally fed to adult turkeys or horses

FDA page: Open in Animal Drugs @ FDA

Species: Cattle, Beef, Heifers
Cattle (Heifers)
Indication
For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), and reduced incidence of liver abscesses.
Dosage
Melengestrol acetate, 0.25 to 0.50 milligram per head per day, plus lasalocid (as lasalocid sodium), 100 to 360 milligrams per head per day, and tylosin (as tylosin phosphate), 90 milligrams per head per day. To attain this amount: Add 0.5 to 2.0 pounds per head per day of a liquid or dry medicated feed containing 0.125 to 1.0 milligram of melengestrol acetate per pound to a medicated feed containing 10 to 30 grams of lasalocid and 8 to 10 grams of tylosin per ton; or Add 0.5 to 2.0 pounds per head per day of a liquid or dry medicated feed containing 0.125 to 1.0 milligram of melengestrol acetate per pound plus 50 to 720 milligrams of lasalocid per pound to 4.5 to 18 pounds of a dry medicated feed containing 10 to 40 grams of tylosin per ton; or Add 0.5 to 2.0 pounds per head per day of a dry pelleted medicated feed containing 0.125 to 1.0 milligram of melengestrol acetate (from a dry Type A article), 50 to 720 milligrams of lasalocid, and 45 to 180 milligrams of tylosin per pound to a ration of non-medicated feed.
Limitations
For heifers being fed in confinement for slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied • Beef
Composition / specifications
Type A medicated article contains 20 grams tylosin (as tylosin phosphate) per pound
Beef Cattle
Indication
For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Corynebacterius pyogenes.
Dosage
8 to 10 grams per ton of feed.
Limitations
Each animal must not receive not more than 90 milligrams per day and not less than 60 milligrams per day. Feed continuously as sole ration.
Swine
Indication

For treatment and control of swine dysentery associated with B. hyodysenteriae.

Dosage

40 to 100 grams per ton of feed.

Limitations

Administer as tylosin phosphate in feed for 2 to 6 weeks, immediately after treatment with tylosin tartrate in drinking water at 250 milligrams per gallon in drinking water for 3 to 10 days.

Indication

For control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis.

Dosage

40 or 100 grams per ton of feed.

Limitations

Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight. As tylosin phosphate.

Indication

For control of swine dysentery associated with Brachyspira hyodysenteriae.

Dosage

40 or 100 grams per ton of feed.

Limitations

Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight. As tylosin phosphate.

Indication

For control of porcine proliferative enteropathies (ileitis) associated with L. intracellularis.

Dosage

100 grams per ton of feed.

Limitations

As tylosin phosphate. Administer for 21 days.

Indication

For the reduction in severity of effects of atrophic rhinitis.

Dosage

100 grams per ton of feed.

Limitations

As tylosin phosphate.

Indication

For control of porcine proliferative enteropathies (PPE, ileitis) associated with L. intracellularis.

Dosage

40 to 100 grams per ton of feed.

Limitations

Administer as tylosin phosphate in feed for 2 to 6 weeks, immediately after treatment with tylosin tartrate in drinking water at 250 milligrams per gallon in drinking water for 3 to 10 days.

FDA page: Open in Animal Drugs @ FDA

Species: Chicken, Broilers Excluding Layers
Composition / specifications
Monensin: Type A medicated article in concentrations of 44, 45, or 60 grams monensin activity per pound.
Tylosin phosphate: Type A medicated article in concentrations of 10 grams of tylosin phosphate activity per pound.
Broiler Chickens
Indication
As an aid in the prevention of coccidiosis caused by Eimeria necatrix, E. tenella, E. acervulina, E. brunette, E. mivati, and E. maxima, for increased rate of weight gain, and improved feed efficiency.
Dosage
Monensin, 90 to 110 grams, plus tylosin phosphate, 4 to 50 grams per ton.
Limitations
Feed continuously as sole ration. In the absence of coccidiosis, the use of monensin with no withdrawal period may limit feed intake resulting in reduced weight gain. Do not feed to laying chickens. Do not allow horses or other equines access to formulations containing monensin. Ingestion of monensin by equines has been fatal. Must be thoroughly mixed in feeds before use. Do not feed undiluted.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing • Cattle, Beef • Chicken, Replacements • Chicken, Layers • Chicken, Broilers • Chicken, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels of tylosin: 0.4, 0.8, 1.6, 20, 40, and 100 grams per pound.
Chickens (laying)
Indication
For improved feed efficiency.
Dosage
20- 50 grams per ton of feed.
Limitations
Chickens (replacements)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma.
Dosage
1,000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24 to 48 hours at 3 to 5 weeks of age.
Limitations
Chickens
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
4-50 grams per ton of feed.
Limitations
Chickens (broilers)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma.
Dosage
800-1000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24- 48 hours at 3 to 5 weeks of age.
Limitations
Cattle (beef)
Indication
For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Corynebacterius pyogenes.
Dosage
8-10 grams per ton of feed.
Limitations
Each animal must receive not more than 90 milligrams per day and not less than 60 milligrams per day. Feed continuously as sole ration.
Swine
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
100 grams per ton of feed.
Limitations
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
10- 100 grams per ton of feed. Pre-starter or starter ration: 20-100 grams per ton. Grower ration: 20-40 grams per ton. Finisher ration: 10-20 grams per ton.
Limitations
Continuous use.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
40- 100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3- 10 days, 40- 100 grams per ton in feed for 2- 6 weeks.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing • Cattle, Beef • Chicken, Replacements • Chicken, Layers • Chicken, Broilers • Chicken, No Use Class Stated Or Implied
Composition / specifications
Tylosin is the antibiotic substance produced by growth of Streptomyces fradiae or the same antibiotic substance produced by any other means. Tylosin present as the phosphate salt, conforms to the appropriate antibiotic standard. Type A medicated article levels of tylosin: 0.4, 0.8, 1.6, 40, and 100 grams per pound
Cattle (beef)
Indication
For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Corynebacterius pyogenes.
Dosage
8- 10 grams per ton of feed.
Limitations
As tylosin phosphate. Each animal must receive not more than 90 milligrams per day and not less than 60 milligrams per day. Feed continuously as sole ration.
Chickens (broilers)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 800- 1000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24- 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Chickens
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 4- 50 grams per ton of feed.
Limitations
As tylosin phosphate.
Chickens (laying)
Indication
For improved feed efficiency.
Dosage
Tylosin, 20- 50 grams per ton of feed.
Limitations
As tylosin phosphate.
Chickens (replacements)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 1,000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24 to 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Swine
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10- 100 grams per ton of feed. Pre-starter or starter: 20- 100 grams per ton. Grower: 20- 40 grams per ton. Finisher: 10- 20 grams per ton.
Limitations
As tylosin phosphate. Continuous use.
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3- 10 days, 40- 100 grams per ton in feed for 2- 6 weeks.
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
As tylosin phosphate.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
As tylosin phosphate.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing
Composition / specifications
Tylosin is the antibiotic substance produced by growth of Streptomyces fradiae or the same antibiotic substance produced by any other means. Tylosin present as the phosphate salt, conforms to the appropriate antibiotic standard. Type A medicated article levels of tylosin: 0.36, 0.4, 0.72, 0.8, or 1 grams per pound
Swine
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
As tylosin phosphate.
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10- 100 grams per ton of feed. Pre-starter or starter: 20- 100 grams per ton. Grower: 20- 40 grams per ton. Finisher: 10- 20 grams per ton.
Limitations
As tylosin phosphate. Continuous use.
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3- 10 days, 40- 100 grams per ton in feed for 2- 6 weeks.
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
As tylosin phosphate.

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Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels, a combination of equal amounts of tylosin and sulfamethazine: 5, 10, 20, or 40 grams per pound each.
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).
Dosage
Tylosin, 100 grams per ton of feed plus sulfamethazine, 100 grams per ton of feed.
Limitations
As tylosin phosphate. Withdraw 15 days before slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing • Cattle, Beef • Chicken, Replacements • Chicken, Layers • Chicken, Broilers • Chicken, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels of tylosin: 4 and 10 grams per pound
Cattle (Beef)
Indication
For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Corynebacterius pyogenes.
Dosage
8- 10 grams per ton of feed.
Limitations
As tylosin phosphate. Each animal must receive not more than 90 milligrams per day and not less than 60 milligrams per day. Feed continuously as sole ration.
Swine
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3 10 days, 40- 100 grams per ton in feed for 2- 6 weeks.
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
As tylosin phosphate.
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10- 100 grams per ton of feed. Pre-starter or starter: 20- 100 grams per ton. Grower: 20- 40 grams per ton. Finisher: 10- 20 grams per ton.
Limitations
As tylosin phosphate. Continuous use.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
As tylosin phosphate.
Chickens (Replacements)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 1,000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24 to 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Chickens (Broilers)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 800- 1000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24- 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Chickens
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 4- 50 grams per ton of feed.
Limitations
As tylosin phosphate.
Chickens (Layers)
Indication
For improved feed efficiency.
Dosage
Tylosin, 20- 50 grams per ton of feed.
Limitations
As tylosin phosphate.

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Species: Chicken, No Use Class Stated Or Implied
Composition / specifications
Type A medicated articles: 2.4 and 8 grams per pound.
Chickens
Indication
Control of infestations of large roundworms (Ascaris galli) cecal worms (Heterakis gallinae,), and capillary worms (Capillaria obsignata); growth promotion and feed efficiency.
Dosage
8-12 grams per ton of Hygromycin B in combination with 4-50 grams per ton of Tylosin.
Limitations
As tylosin phosphate.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing
Composition / specifications
Type A medicated article levels of tylosin: 5 grams per pound
Swine
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10- 100 grams per ton of feed. Pre-starter or starter: 20- 100 grams per ton. Grower: 20- 40 grams per ton. Finisher: 10- 20 grams per ton.
Limitations
Continuous use.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3- 10 days, 40- 100 grams per ton in feed for 2- 6 weeks.
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing • Cattle, Beef • Chicken, Replacements • Chicken, Layers • Chicken, Broilers • Chicken, No Use Class Stated Or Implied
Composition / specifications
Tylosin is the antibiotic substance produced by growth of Streptomyces fradiae or the same antibiotic substance produced by any other means. Tylosin present as the phosphate salt, conforms to the appropriate antibiotic standard. Type A medicated article levels of tylosin: 5, 10, 20, or 40 grams per pound
Cattle (beef)
Indication
For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Corynebacterius pyogenes.
Dosage
8- 10 grams per ton of feed.
Limitations
As tylosin phosphate. Each animal must receive not more than 90 milligrams per day and not less than 60 milligrams per day. Feed continuously as sole ration.
Chickens (broiler)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 800- 1000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24- 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Chickens
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 4- 50 grams per ton of feed.
Limitations
As tylosin phosphate.
Chickens (laying)
Indication
For improved feed efficiency.
Dosage
Tylosin, 20- 50 grams per ton of feed.
Limitations
As tylosin phosphate.
Chickens (replacements)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 1,000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24 to 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Swine
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
As tylosin phosphate.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
As tylosin phosphate.
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3- 10 days, 40- 100 grams per ton in feed for 2- 6 weeks.
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10- 100 grams per ton of feed. Pre-starter or starter: 20- 100 grams per ton. Grower: 20- 40 grams per ton. Finisher: 10- 20 grams per ton.
Limitations
As tylosin phosphate. Continuous use.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels, a combination of equal amounts of tylosin and sulfamethazine: 4, 10, or 20 grams per pound each.
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); and control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).
Dosage
Tylosin, 100 grams plus sulfamethazine, 100 grams.
Limitations
As tylosin phosphate. Withdraw 15 days before slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing
Composition / specifications
Tylosin is the antibiotic substance produced by growth of Streptomyces fradiae or the same antibiotic substance produced by any other means. Tylosin present as the phosphate salt, conforms to the appropriate antibiotic standard. Type A medicated article levels of tylosin: 4, 10 grams per pound
Swine
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
As tylosin phosphate.
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3- 10 days, 40- 100 grams per ton in feed for 2- 6 weeks.
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10- 100 grams per ton of feed. Pre-starter or starter: 20- 100 grams per ton. Grower: 20- 40 grams per ton. Finisher: 10- 20 grams per ton.
Limitations
As tylosin phosphate. Continuous use.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
As tylosin phosphate.

FDA page: Open in Animal Drugs @ FDA

Species: Chicken, Broilers
Composition / specifications
Narasin: Type A medicated article in concentrations of 36, 45, 54, 72, or 90 grams narasin activity per pound.
Tylosin phosphate: Type A medicated article in concentrations of 10 grams of tylosin phosphate activity per pound.
Broiler Chickens
Indication
For the prevention of coccidiosis caused by Eimeria necatrix, E. tenella, E. acervulina, E. brunetti, E. mivati, and E. maxima, and for increased rate of weight gain and improved feed efficiency in broiler chickens.
Dosage
Narasin, 54 to 72 grams, plus tylosin, 4 to 50 grams per ton
Limitations
For broiler chickens only. Feed continuously as sole ration. Do not allow adult turkeys, horses, or other equines access to formulations containing narasin. Ingestion of narasin by these species has been fatal.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing
Composition / specifications
Type A medicated article levels of tylosin: 2, 5, 10, 20, 40 grams per pound.
Swine
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3- 10 days, 40- 100 grams per ton in feed for 2- 6 weeks.
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10- 100 grams per ton of feed. Pre-starter or starter: 20- 100 grams per ton. Grower: 20- 40, grower grams per ton. Finisher: 10- 20, finisher grams per ton.
Limitations
As tylosin phosphate. Continuous use.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
As tylosin phosphate.
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
As tylosin phosphate.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing
Composition / specifications
Type A medicated articles containing 2 grams of tylosin per pound.
Swine
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10- 100 grams per ton of feed. Pre-starter or starter: 20- 100 grams per ton. Grower: 20- 40 grams per ton. Finisher: 10- 20 grams per ton.
Limitations
As tylosin phosphate. Continuous use.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
As tylosin phosphate.
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3- 10 days, 40- 100 grams per ton in feed for 2- 6 weeks.
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
As tylosin phosphate.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
558.630 Tylosin and sulfamethazine.

Specifications:
Type A medicated article levels, a combination of equal amounts of tylosin and sulfamethazine: 5, 10, 20, or 40 grams per pound each.

Conditions of use:

Swine

Amount:
Tylosin, 100 grams plus sulfamethazine, 100 grams.

Indications:
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).

Limitations:
As tylosin phosphate. Withdraw 15 days before slaughter.
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).
Dosage
Tylosin, 100 grams plus sulfamethazine, 100 grams.
Limitations
As tylosin phosphate. Withdraw 15 days before slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing • Cattle, Beef • Chicken, Replacements • Chicken, Layers • Chicken, Broilers • Chicken, No Use Class Stated Or Implied
Composition / specifications
Type A medicated articles containing tylosin phosphate at 0.4, 0.8, 1, 8, 10, and 40 grams per pound.
Chickens (replacements)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma gallisepticum.
Dosage
Tylosin, 1,000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24 to 48 hours at 3 to 5 weeks of age.
Limitations
Swine
Indication
For control of swine dysentery associated with Brachyspira hyodysenteriae, and for control of porcine proliferative enteropathies (ileitis) associated with Lawsonia intracellularis.
Dosage
Tylosin, 40 or 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
Indication
For the treatment and control of swine dysentery associated with Brachyspira hyodysenteriae, and for control of porcine proliferative enteropathies (ileitis) associated with Lawsonia intracellularis.
Dosage
Tylosin, 40-100 grams per ton.
Limitations
Administer as tylosin phosphate in feed for 2 to 6 weeks, immediately after treatment with tylosin tartrate in drinking water.
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10-100 grams per ton of feed. Continuous use as follows: Grams per ton: 20-100, prestarter or starter; 20-40, grower; 10-20, finisher.
Limitations
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
Cattle (beef)
Indication
For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes.
Dosage
8-10 grams per ton of feed.
Limitations
Each animal must receive not more than 90 milligrams per day and not less than 60 milligrams per day. Feed continuously as sole ration.
Chickens (broilers)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma gallisepticum.
Dosage
Tylosin, 800-1000 grams. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24-48 hours at 3 to 5 weeks of age.
Limitations
Withdraw 5 days before slaughter.
Chickens (laying)
Indication
For improved feed efficiency.
Dosage
Tylosin, 20-50 grams per ton of feed.
Limitations
Chickens
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 4-50 grams per ton of feed.
Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels, a combination of equal amounts of tylosin and sulfamethazine: 40 grams per pound each.
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).
Dosage
Tylosin, 100 grams per ton of feed plus sulfamethazine, 100 grams per ton of feed.
Limitations
Withdraw 15 days before swine are slaughtered.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels, a combination of equal amounts of tylosin and sulfamethazine: 40 grams per pound each.
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).
Dosage
100 grams tylosin per ton of feed plus 100 grams sulfamethazine per ton of feed.
Limitations
Withdraw 15 days before slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing • Cattle, Beef • Chicken, Replacements • Chicken, Layers • Chicken, Broilers • Chicken, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article: 1, 2, 8, or 10 grams per pound
Broiler Chickens
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma galisepticum.
Dosage
Tylosin, 800-1000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24-48 hours at 3 to 5 weeks of age.
Limitations
Withdraw 5 days before slaughter.
Replacement Chickens
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma galisepticum.
Dosage
Tylosin, 1000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24-48 hours at 3 to 5 weeks of age.
Limitations
Withdraw 5 days before slaughter.
Chickens
Indication
For increased rate of gain and improved feed efficiency
Dosage
Tylosin, 4-50 grams per ton of feed.
Limitations
Beef Cattle
Indication
For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Corynebacterium pyogenes
Dosage
8-10 grams per ton of feed.
Limitations
Each animal must receive not more than 90 milligrams per day and not less than 60 milligrams per day. Feed continuously as sole ration.
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
Indication
For increased rate of gain and improved feed efficiency
Dosage
Tylosin, 10-100 grams per ton of feed. Pre-starter or starter ration: 20-100 grams per ton. Grower ration: 20-40 grams per ton. Finisher ration: 10-20 grams per ton.
Limitations
Continuous use.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40-100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40-100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 grams per gallon in drinking water for 3-10 days, 40-100 grams per ton in feed for 2-6 weeks.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing • Cattle, Beef • Chicken, Replacements • Chicken, Layers • Chicken, Broilers • Chicken, No Use Class Stated Or Implied
Composition / specifications
Tylosin is the antibiotic substance produced by growth of Streptomyces fradiae or the same antibiotic substance produced by any other means. Tylosin present as the phosphate salt, conforms to the appropriate antibiotic standard. Type A medicated article levels of tylosin: 1, 5, 10, 20, or 40 grams per pound
Cattle (beef)
Indication
For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Corynebacterius pyogenes.
Dosage
8- 10 grams per ton of feed.
Limitations
As tylosin phosphate. Each animal must receive not more than 90 milligrams per day and not less than 60 milligrams per day. Feed continuously as sole ration.
Chickens (broilers)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma.
Dosage
Tylosin, 800- 1000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24- 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Chickens
Indication
Tylosin, 4- 50 grams per ton of feed.
Dosage
Tylosin, 4- 50 grams per ton of feed.
Limitations
As tylosin phosphate.
Chickens (laying)
Indication
For improved feed efficiency.
Dosage
Tylosin, 20- 50 grams per ton of feed.
Limitations
As tylosin phosphate.
Chickens (replacements)
Indication
Tylosin, 1,000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24 to 48 hours at 3 to 5 weeks of age.
Dosage
Tylosin, 1,000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24 to 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Swine
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
As tylosin phosphate.
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10- 100 grams per ton of feed. Pre-starter or starter: 20- 100 grams per ton. Grower: 20- 40 grams per ton. Finisher: 10- 20 grams per ton.
Limitations
For increased rate of weight gain and improved feed efficiency.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
Prevention of swine dysentery (vibrionic).
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed.
Limitations
Treatment and control of swine dysentery (vibrionic).

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels, a combination of equal amounts of tylosin and sulfamethazine: 5, 10, 20, or 40 grams per pound each.
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).
Dosage
Tylosin, 100 grams plus sulfamethazine, 100 grams.
Limitations
As tylosin phosphate. Withdraw 15 days before slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing
Composition / specifications
Tylosin is the antibiotic substance produced by growth of Streptomyces fradiae or the same antibiotic substance produced by any other means. Tylosin present as the phosphate salt, conforms to the appropriate antibiotic standard. Type A medicated article containing 10 grams per pound of tylosin.
Swine
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10-100 grams per ton of feed. Pre-starter or starter: 20 to 100 grams per ton. Grower: 20 to 40 grams per ton. Finisher: 10 to 20 grams per ton.
Limitations
As tylosin phosphate. Continuous use.

FDA page: Open in Animal Drugs @ FDA

Species: Chicken, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels of 10, 40, and 100 grams per pound tylosin
Beef Cattle
Indication
For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Actinomyces (Corynebacterium) pyogenes.
Dosage
8-10 grams per ton of feed.
Limitations
As tylosin phosphate. Each animal must receive not more than 90 milligrams per day and not less than 60 milligrams per day. Feed continuously as sole ration.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing • Cattle, Beef • Chicken, Replacements • Chicken, Layers • Chicken, Broilers • Chicken, No Use Class Stated Or Implied
Composition / specifications
Tylosin is the antibiotic substance produced by growth of Streptomyces fradiae or the same antibiotic substance produced by any other means. Tylosin present as the phosphate salt, conforms to the appropriate antibiotic standard. Type A medicated article levels of tylosin: 5, 10, 20, and 40 grams per pound
Cattle (beef)
Indication
For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Corynebacterius pyogenes.
Dosage
8- 10 grams per ton of feed.
Limitations
As tylosin phosphate. Each animal must receive not more than 90 milligrams per day and not less than 60 milligrams per day. Feed continuously as sole ration.
Chickens (broilers)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 800- 1000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24- 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Chickens
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 4- 50 grams per ton of feed.
Limitations
As tylosin phosphate.
Chickens (laying)
Indication
For improved feed efficiency.
Dosage
Tylosin, 20- 50 grams per ton of feed.
Limitations
As tylosin phosphate.
Chickens (replacements)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 1,000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24 to 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Swine
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
As tylosin phosphate.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
As tylosin phosphate.
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10- 100 grams per ton of feed. Pre-starter or starter: 20- 100 grams per ton. Grower: 20- 40 grams per ton. Finisher: 10- 20 grams per ton.
Limitations
As tylosin phosphate. Continuous use.
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3- 10 days, 40- 100 grams per ton in feed for 2- 6 weeks.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing • Cattle, Beef • Chicken, Replacements • Chicken, Layers • Chicken, Broilers • Chicken, No Use Class Stated Or Implied
Beef Cattle
Indication
For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Corynebacterius pyogenes.
Dosage
8- 10 grams per ton of feed.
Limitations
Each animal must receive not more than 90 milligrams per day and not less than 60 milligrams per day. Feed continuously as sole ration.
Broiler Chickens
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 800- 1000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24- 48 hours at 3 to 5 weeks of age.
Limitations
Withdraw 5 days before slaughter.
Laying Chickens
Indication
For improved feed efficiency.
Dosage
Tylosin, 20- 50 grams per ton of feed.
Limitations
Replacement Chickens
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 1,000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24 to 48 hours at 3 to 5 weeks of age.
Limitations
Withdraw 5 days before slaughter.
Chickens
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 4- 50 grams per ton of feed.
Limitations
Swine
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10- 100 grams per ton of feed. Pre-starter or starter: 20- 100 grams per ton. Grower: 20- 40 grams per ton. Finisher: 10- 20 grams per ton.
Limitations
Continuous use.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3- 10 days, 40- 100 grams per ton in feed for 2- 6 weeks.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing • Cattle, Beef • Chicken, Replacements • Chicken, Layers • Chicken, Broilers • Chicken, No Use Class Stated Or Implied
Chickens
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 4- 50 grams per ton of feed.
Limitations
As tylosin phosphate.
Swine
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
As tylosin phosphate.
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10- 100 grams per ton of feed. Pre-starter or starter: 20- 100 grams per ton. Grower: 20- 40 grams per ton. Finisher: 10- 20 grams per ton.
Limitations
As tylosin phosphate. Continuous use.
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3- 10 days, 40- 100 grams per ton in feed for 2- 6 weeks.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
Limitations: As tylosin phosphate.
Broiler Chickens
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 800- 1000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24- 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Replacement Chickens
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 1,000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24 to 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Cattle (Beef)
Indication
For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Corynebacterius pyogenes.
Dosage
8- 10 grams per ton of feed.
Limitations
As tylosin phosphate. Each animal must receive not more than 90 milligrams per day and not less than 60 milligrams per day. Feed continuously as sole ration.
Laying Chickens
Indication
For improved feed efficiency.
Dosage
Tylosin, 20- 50 grams per ton of feed.
Limitations
As tylosin phosphate.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels, a combination of equal amounts of tylosin and sulfamethazine: 5, 10, 20, or 40 grams per pound each.
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).
Dosage
Tylosin, 100 grams per ton of feed plus sulfamethazine, 100 grams per ton of feed.
Limitations
As tylosin phosphate. Withdraw 15 days before slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels, a combination of equal amounts of tylosin and sulfamethazine: 5, 10, 20, or 40 grams per pound each.
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).
Dosage
Tylosin, 100 grams per ton of feed plus sulfamethazine, 100 grams per ton of feed.
Limitations
Withdraw 15 days before slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels, a combination of equal amounts of tylosin and sulfamethazine: 5, 10, 20, or 40 grams per pound each
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).
Dosage
Tylosin, 100 grams per ton of feed plus sulfamethazine, 100 grams per ton of feed.
Limitations
As tylosin phosphate. Withdraw 15 days before slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article in a combination of equal amounts of tylosin and sulfamethazine 5, 10, 20, or 40 grams per pound each.
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).
Dosage
Tylosin, 100 grams per ton of feed plus sulfamethazine, 100 grams per ton of feed.
Limitations
As tylosin phosphate.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels, a combination of equal amounts of tylosin and sulfamethazine: 5, 10, 20, or 40 grams per pound each.
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).
Dosage
Tylosin, 100 grams per ton of feed plus sulfamethazine, 100 grams per ton of feed.
Limitations
As tylosin phosphate. Withdraw 15 days before slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing • Cattle, Beef • Chicken, Replacements • Chicken, Layers • Chicken, Broilers • Chicken, No Use Class Stated Or Implied
Composition / specifications
Tylosin is the antibiotic substance produced by growth of Streptomyces fradiae or the same antibiotic substance produced by any other means. Tylosin present as the phosphate salt, conforms to the appropriate antibiotic standard. Type A medicated article levels of tylosin: 5, 10, 20, 40, grams per pound
Cattle (beef)
Indication
For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Corynebacterius pyogenes.
Dosage
8- 10 grams per ton of feed.
Limitations
As tylosin phosphate. Each animal must receive not more than 90 milligrams per day and not less than 60 milligrams per day. Feed continuously as sole ration.
Chickens (broilers)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 800- 1000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24- 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Chickens
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 4- 50 grams per ton of feed.
Limitations
As tylosin phosphate.
Chickens (laying)
Indication
For improved feed efficiency.
Dosage
Tylosin, 20- 50 grams per ton of feed.
Limitations
As tylosin phosphate.
Chickens (replacements)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 1,000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24 to 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Swine
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10- 100 grams per ton of feed. Pre-starter or starter: 20- 100 grams per ton. Grower: 20- 40 grams per ton. Finisher: 10- 20 grams per ton.
Limitations
As tylosin phosphate. Continuous use.
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
As tylosin phosphate.
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3- 10 days, 40- 100 grams per ton in feed for 2- 6 weeks.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
As tylosin phosphate.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing • Cattle, Beef • Chicken, Replacements • Chicken, Layers • Chicken, Broilers • Chicken, No Use Class Stated Or Implied
Composition / specifications
Tylosin is the antibiotic substance produced by growth of Streptomyces fradiae or the same antibiotic substance produced by any other means. Tylosin present as the phosphate salt, conforms to the appropriate antibiotic standard. Type A medicated article levels of tylosin: 5, 10, 20, and 40 grams per pound
Cattle (beef)
Indication
For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Corynebacterius pyogenes.
Dosage
8- 10 grams per ton of feed.
Limitations
As tylosin phosphate. Each animal must receive not more than 90 milligrams per day and not less than 60 milligrams per day. Feed continuously as sole ration.
Chickens (broilers)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma.
Dosage
Tylosin, 800- 1000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24- 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Chickens
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 4- 50 grams per ton of feed.
Limitations
As tylosin phosphate.
Chickens (laying)
Indication
For improved feed efficiency.
Dosage
Tylosin, 20- 50 grams per ton of feed.
Limitations
As tylosin phosphate.
Chickens (replacements)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 1,000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24 to 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Swine
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
As tylosin phosphate.
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3- 10 days, 40- 100 grams per ton in feed for 2- 6 weeks.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
As tylosin phosphate.
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10- 100 grams per ton of feed. Pre-starter or starter: 20- 100 grams per ton. Grower: 20- 40 grams per ton. Finisher: 10- 20 grams per ton.
Limitations
As tylosin phosphate. Continuous use.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels, a combination of equal amounts of tylosin and sulfamethazine: 5, 10, 20, or 40 grams per pound each.
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).
Dosage
Tylosin, 100 grams per ton of feed plus sulfamethazine, 100 grams per ton of feed.
Limitations
As tylosin phosphate. Withdraw 15 days before slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels, a combination of equal amounts of tylosin and sulfamethazine: 5, 10, 20, or 40 grams per pound each.
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).
Dosage
Tylosin, 100 grams per ton of feed plus sulfamethazine, 100 grams per ton of feed.
Limitations
As tylosin phosphate. Withdraw 15 days before slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels, a combination of equal amounts of tylosin and sulfamethazine: 5, 10, 20, or 40 grams per pound each.
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).
Dosage
Tylosin, 100 grams per ton of feed plus sulfamethazine, 100 grams per ton of feed.
Limitations
As tylosin phosphate. Withdraw 15 days before slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels, a combination of equal amounts of tylosin and sulfamethazine: 5, 10, 20, or 40 grams per pound each.
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).
Dosage
Tylosin, 100 grams per ton of feed plus sulfamethazine, 100 grams per ton of feed.
Limitations
As tylosin phosphate. Withdraw 15 days before slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels, a combination of equal amounts of tylosin and sulfamethazine: 5, 10, 20, or 40 grams per pound each
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).
Dosage
Tylosin, 100 grams plus sulfamethazine, 100 grams.
Limitations
As tylosin phosphate. Withdraw 15 days before slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing • Cattle, Beef • Chicken, Replacements • Chicken, Layers • Chicken, Broilers • Chicken, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels of tylosin: 10, and 40 grams per pound
Beef Cattle
Indication
For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Corynebacterius pyogenes.
Dosage
8- 10 grams per ton of feed.
Limitations
As tylosin phosphate. Each animal must receive not more than 90 milligrams per day and not less than 60 milligrams per day. Feed continuously as sole ration.
Broiler Chickens
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 800- 1000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24- 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Chickens
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 4- 50 grams per ton of feed.
Limitations
Laying Chickens
Indication
For improved feed efficiency.
Dosage
Tylosin, 20- 50 grams per ton of feed.
Limitations
Replacement Chickens
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 1,000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24 to 48 hours at 3 to 5 weeks of age.
Limitations
Withdraw 5 days before slaughter.
Swine
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10- 100 grams per ton of feed. Pre-starter or starter: 20- 100 grams per ton. Grower: 20- 40 grams per ton. Finisher: 10- 20 grams per ton.
Limitations
Continuous use.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3- 10 days, 40- 100 grams per ton in feed for 2- 6 weeks.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied • Cattle, Beef • Chicken, Replacements • Chicken, Layers • Chicken, Broilers • Chicken, No Use Class Stated Or Implied
Composition / specifications
Type A medicated articles of 20 and 40 grams per pound tylosin.
Swine
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40-100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
As tylosin phosphate.
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40-100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3-10 days, 40-100 grams per ton in feed for 2-6 weeks.
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10-100 grams per ton of feed. Pre-starter or starter: 20-100 grams per ton. Grower: 20-40 grams per ton. Finisher: 10-20 grams per ton.
Limitations
As tylosin phosphate. Continuous use.
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
As tylosin phosphate.
Cattle (Beef)
Indication
For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Actinomyces (Corynebacterium) pyogenes.
Dosage
8-10 grams per ton of feed.
Limitations
As tylosin phosphate. Each animal must receive not more than 90 milligrams per day and not less than 60 milligrams per day. Feed continuously as sole ration.
Chickens (Replacements)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma gallisepticum.
Dosage
Tylosin, 1,000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24 to 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Chickens (Broilers)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma gallisepticum.
Dosage
800-1000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24-48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.'
Chickens (Laying)
Indication
For improved feed efficiency.
Dosage
Tylosin, 20-50 grams per ton of feed.
Limitations
As tylosin phosphate.
Chickens
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 4-50 grams per ton of feed.
Limitations
As tylosin phosphate.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels, a combination of equal amounts of tylosin and sulfamethazine: 5, 10, 20, or 40 grams per pound each.
Swine
Indication
As tylosin phosphate. Withdraw 15 days before slaughter.
Dosage
Tylosin, 100 grams per ton of feed plus sulfamethazine, 100 grams per ton of feed.
Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Chicken, Broilers
Composition / specifications
Tylosin: 10, 40 or 100 grams of tylosin
activity per pound.
Salinomycin: 30 or 60 grams of salinomycin
activity per pound.
Broiler Chickens
Indication
For increased rate of weight gain and improved feed efficiency, and as an aid in the prevention of coccidiosis caused by Eimeria tenella, E. necatrix, E. acervulina, E. maxima, E. brunetti, and E. mivati in broiler chickens.
Dosage
Tylosin - 4 to 50 g/ton Salinomycin - 40 to 60 g/ton
Limitations
For broiler chickens only. Do not feed to laying hens. Not approved for use with pellet binders. May be fatal if accidentally fed to adult turkeys or horses.

FDA page: Open in Animal Drugs @ FDA

Species: Chicken, Replacements • Chicken, Layers • Chicken, Broilers • Chicken, No Use Class Stated Or Implied
Composition / specifications
Tylosin is the antibiotic substance produced by growth of Streptomyces fradiae or the same antibiotic substance produced by any other means. Tylosin present as the phosphate salt, conforms to the appropriate antibiotic standard. Type A medicated article levels of tylosin: 10, 40, 100 grams per pound.
Chickens (broilers)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma.
Dosage
800-1000 grams Tylosin per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24-48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate.
Chickens
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
4-50 grams Tylosin per ton of feed.
Limitations
As tylosin phosphate.
Chickens (laying)
Indication
For improved feed efficiency.
Dosage
20-50 grams Tylosin per ton of feed.
Limitations
As tylosin phosphate.
Chickens (replacements)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
1,000 grams Tylosin per ton. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24 to 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels, a combination of equal amounts of tylosin and sulfamethazine: 5, 10, 20, or 40 grams per pound each
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).
Dosage
Tylosin, 100 grams plus sulfamethazine, 100 grams.
Limitations
As tylosin phosphate. Withdraw 15 days before slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels, a combination of equal amounts of tylosin and sulfamethazine: 5, 10, 20, or 40 grams per pound each.
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes).
Dosage
Tylosin, 100 grams plus sulfamethazine, 100 grams.
Limitations
As tylosin phosphate. Withdraw 15 days before slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing • Cattle, Beef • Chicken, Replacements • Chicken, Layers • Chicken, Broilers • Chicken, No Use Class Stated Or Implied
Composition / specifications
Tylosin is the antibiotic substance produced by growth of Streptomyces fradiae or the same antibiotic substance produced by any other means. Tylosin present as the phosphate salt, conforms to the appropriate antibiotic standard. Type A medicated article levels of tylosin: 10, 40 grams per pound
Cattle (beef)
Indication
For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Corynebacterius pyogenes.
Dosage
8- 10 grams per ton of feed.
Limitations
As tylosin phosphate. Each animal must receive not more than 90 milligrams per day and not less than 60 milligrams per day. Feed continuously as sole ration.
Chickens (broilers)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 800- 1000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24- 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Chickens
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 4- 50 grams per ton of feed.
Limitations
As tylosin phosphate.
Chickens (laying)
Indication
For improved feed efficiency.
Dosage
Tylosin, 20- 50 grams per ton of feed.
Limitations
As tylosin phosphate.
Chickens (replacements)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma
Dosage
Tylosin, 1,000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24 to 48 hours at 3 to 5 weeks of age.
Limitations
As tylosin phosphate. Withdraw 5 days before slaughter.
Swine
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3- 10 days, 40- 100 grams per ton in feed for 2- 6 weeks.
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10- 100 grams per ton of feed. Pre-starter or starter: 20- 100 grams per ton. Grower: 20- 40 grams per ton. Finisher: 10- 20 grams per ton.
Limitations
As tylosin phosphate. Continuous use.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
As tylosin phosphate.
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
As tylosin phosphate.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, No Use Class Stated Or Implied
Composition / specifications
Type A medicated articles: 2.4 and 8 grams per pound.
Swine
Indication
Control of infestations of large roundworms (Ascaris suis), nodular worms Oesophagostomum dentatum), and whipworms (Trichuris suis); growth promotion and feed efficiency.
Dosage
12 grams per ton of Hygromycin B in combination with 10-100 grams per ton of Tylosin. Up to 40 pounds body weight- 20 to 100 tylosin grams per ton of feed. 41 to 100 pounds body weight- 20 to 40 tylosin grams per ton of feed. 101 to market weight pounds body weight- 10 to 20 tylosin grams per ton of feed.
Limitations
As tylosin phosphate. Feed continuously.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing
Composition / specifications
Tylosin is the antibiotic substance produced by growth of Streptomyces fradiae or the same antibiotic substance produced by any other means. Tylosin present as the phosphate salt, conforms to the appropriate antibiotic standard. Type A medicated article: 10 grams per pound
Swine
Indication
Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
As tylosin phosphate.
Indication
For increased rate of gain and improved feed efficiency
Dosage
Tylosin, 10-100 grams per ton of feed. Pre-starter or starter: 20-100 grams per ton. Grower: 20-40 grams per ton. Finisher: 10-20 grams per ton.
Limitations
As tylosin phosphate. Continuous use.
Indication
Prevention of swine dysentery (vibrionic)
Dosage
Tylosin, 40-100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
Prevention of swine dysentery (vibrionic)
Indication
Tylosin, 40-100 grams per ton of feed.
Dosage
Tylosin, 40-100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 grams per gallon in drinking water for 3-10 days, 40-100 grams per ton in feed for 2-6 weeks.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Starting • Swine, Growing • Swine, Finishing • Cattle, Beef • Chicken, Replacements • Chicken, Layers • Chicken, Broilers • Chicken, No Use Class Stated Or Implied
Composition / specifications
Type A medicated article levels of tylosin: 0.8, 2, 4, 8, 10, 40, and 100 grams per pound.
Chickens (laying)
Indication
For improved feed efficiency.
Dosage
Tylosin, 20- 50 grams per ton of feed.
Limitations
Chickens
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 4- 50 grams per ton of feed.
Limitations
Swine
Indication
Maintaining weight gains and feed efficiency in presence of atrophic rhinitis.
Dosage
Tylosin, 100 grams per ton of feed.
Limitations
Indication
For increased rate of weight gain and improved feed efficiency.
Dosage
Tylosin, 10- 100 grams per ton of feed. Pre-starter and starter: 20- 100 grams per ton. Grower: 20- 40 grams per ton. Finisher: 10- 20 grams per ton.
Limitations
For continuous use.
Indication
Prevention of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed. Use 100 grams per ton for at least 3 weeks followed by 40 grams per ton until market weight.
Limitations
Indication
Treatment and control of swine dysentery (vibrionic).
Dosage
Tylosin, 40- 100 grams per ton of feed.
Limitations
Administer in feed as tylosin phosphate after treatment with tylosin in drinking water as tylosin base; 0.25 gram per gallon in drinking water for 3- 10 days, 40- 100 grams per ton in feed for 2- 6 weeks.
Chickens (broilers)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma.
Dosage
Tylosin, 800- 1000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24- 48 hours at 3 to 5 weeks of age.
Limitations
Withdraw 5 days before slaughter.
Cattle (beef)
Indication
For reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Corynebacterius pyogenes.
Dosage
8- 10 grams per ton of feed.
Limitations
Each animal must receive not more than 90 milligrams per day and not less than 60 milligrams per day. Feed continuously as sole ration.
Chickens (replacements)
Indication
To aid in the control of chronic respiratory disease caused by Mycoplasma.
Dosage
Tylosin, 1,000 grams per ton of feed. Administer in feed to chickens 0 to 5 days of age, follow with second administration in feed for 24 to 48 hours at 3 to 5 weeks of age.
Limitations
Withdraw 5 days before slaughter.

FDA page: Open in Animal Drugs @ FDA

Official Documents (FDA)

Direct links to FDA-hosted PDFs and SPL packages (when available).

Documents
  • Summary
    This supplement provides for revised indications for the combined use of ractopamine hydrochloride and tylosin phosphate in finishing swine, based on the November 13, 2008,  supplemental approval for TYLAN (under NADA 012-491), which added an alternate dosage and feeding regimen for the porcine proliferative enteropathies (PPE, ileitis) claim.  The new claim is:  Ractopamine hydrochloride 4.5 to 9.0 g/ton and tylosin phosphate 40 to 100 g/ton for 2 to 6 weeks immediately after medicating with 250 mg tylosin tartrate (as TYLAN Soluble) per gallon in drinking water for 3 to 10 days:  For increased rate of weight gain, improved feed efficiency and increased carcass leanness in finishing swine, weighing not less than 150 lbs, fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter; for treatment and control of swine dysentery associated with Brachyspira hyodysenteriae; and for control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis. This supplement also corrects the Type B and C medicated feed (Blue Bird) labeling for the control of swine dysentery and control of ileitis claim to reflect the two point dose approval (40 or 100 g/ton) for tylosin phosphate rather than the range of 40 to 100 g/ton erroneously codified in 21 CFR 558.625(f)(1)(vi)(b) for tylosin phosphate.
  • Summary
    This supplement provides for the combined use of ractopamine hydrochloride and tylosin phosphate in swine in excess of 240 lb and
  • Summary
    To provide for the use of ractopamine and tylosin single-ingredient Type A medicated articles to make a combination drug type C medicated feed and to add the claim for the prevention of swine dysentery in finishing swine.
  • Summary
    1) For increased weight gain, improved feed efficiency and increased carcass leanness in finishing swine fed a complete ration containing at least 16% crude protein from 150 lb (68kg) to 240 lb (109 kg) body weight, and for prevention and/or control of porcine proliferative enteropathies (ileitis) associated with Lawsonia intracellularis. 2) For improved feed efficiency and increased carcass leanness in finishing swine fed a complete ration containing at least 16% crude protein from 150 lb (68kg) to 240 lb (109 kg) body weight, and for prevention and/or control of porcine proliferative enteropathies (ileitis) associated with Lawsonia intracellularis.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    Ractopamine hydrochloride (8.2 to 24.6 g/ton) in combination with monensin sodium (10 to 40 g/ton) and tylosin phosphate (8 to 10 g/ton): For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

    Ractopamine hydrochloride (9.8 to 24.6 g/ton) in combination with monensin sodium (10 to 40 g/ton) and tylosin phosphate (8 to 10 g/ton): For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

    Ractopamine hydrochloride top dress (not to exceed 800g/ton) plus monensin sodium (10 to 40 g/ton) in combination with tylosin phosphate (8 to 10 g/ton): For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction in incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter during the last 28 to 42 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes and suppression of estrus (heat) in heifers fed in confinement for slaughter for the last 28 to 42 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    Ractopamine hydrochloride (8.2 to 24.6 g/ton) in combination with monensin USP (10 to 40 g/ton) and tylosin phosphate (8 to 10 g/ton): For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

    Ractopamine hydrochloride (9.8 to 24.6 g/ton) in combination with monensin USP (10 to 40 g/ton) and tylosin phosphate (8 to 10 g/ton): For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to E. bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

    Ractopamine hydrochloride top dress (not to exceed 800 g/ton) plus monensin USP (10 to 40 g/ton) in combination with tylosin phosphate (8 to 10 g/ton): For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to E. bovis and E. zuernii and reduction in incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter during the last 28 to 42 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium ( Actinomyces) pyogenes and suppression of estrus (heat) in heifers fed in confinement for slaughter for the last 28 to 42 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For the prevention of coccidiosis caused by Eimeria bovis and E. zuernii, for improved feed efficiency, and for reduction in the incidence of liver abscesses caused by Fusobacterium necrophorum and Actinomyces pyogenes in growing-finishing cattle being fed in confinement for slaughter.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    This supplement provides for an increase in the upper dose limit of monensin to 480 mg per head per day based upon the October 19, 2009, supplemental approval (NADA 138-870, C-0036) for Rumensin® and an update of the name of the tylosin targeted bacteria to Arcanobacterium pyogenes based on the November 7, 2006, approval (NADA 012-491,C-0318) for Tylan®.

  • Summary
    For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), reduced incidence of liver abscesses caused by Fusobacterium necrophorum and Actinomyces (Corynebacterium) pyogenes, and the prevention and control of coccidiosis due to Eimeria bovis and E. zuernii in heifers being fed in confinement for slaughter.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes, and suppression of estrus (heat) in heifers fed in confinement for slaughter for the last 20 to 40 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    This supplement provides for an increase in the upper dose limit of monensin to 40 g/ton in the combined use of ractopamine hydrochloride, monensin sodium, tylosin phosphate and melengestrol acetate Type A medicated articles, based on the December 1, 2006, supplemental approval for RUMENSIN (under NADA 095-735). This supplement also updates the name of one of tylosin’s targeted bacteria to Arcanobacterium (Actinomyces) pyogenes, based on the November 7, 2006, supplemental approval for TYLAN (under NADA 012-491). In addition, this supplement references an increased monensin tolerance in cattle liver from 0.05 to 0.10 ppm, based on the September 11, 2007, supplemental approval for OPTAFLEXX plus RUMENSIN plus TYLAN plus MGA (under NADA 141-233).

  • Summary
    For suppression of estrus (heat), increased rate of weight gain, improved feed efficiency, increased leanness, the prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Actinomyces (Corynebacterium) pyogenes in heifers being fed in confinement for slaughter for the last 28 to 42 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    These supplements provide for the treatment of the approved combination of melengestrol acetate, monensin and tylosin to be treated as a combination under the provisions of the Animal Drug Availability Act of 1996, and its reference to feed delivered drug combinations. The effect is to provide for the addition of the coccidiosis claim for monensin (0.14 to 0.42 mg/lb body weight depending on the severity of the challenge, up to 360 mg/hd/day) and the addition of the complete tylosin dose range (60 to 90 mg/hd/day) to this combination with melengestrol acetate for heifers being fed in confinement for slaughter.
  • Summary

    This supplement provides for removal of the requirement of a pre-slaughter drug withdrawal period for heifers fed melengestrol acetate when melengestrol acetate is fed in combination with tylosin or with tylosin and monensin. Previous approvals have required a 48 hour pre-slaughter drug withdrawal for heifers fed melengestrol acetate when fed in combination with either tylosin or monensin and tylosin.

  • Summary
    For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), and reduced incidence of liver abscesses in heifers fed in confinement for slaughter.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium pyogenes in heifers fed in confinement for slaughter.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    Ractopamine hydrochloride (8.2 to 24.6 g/ton) in combination with monensin USP (10 to 40 g/ton) and tylosin phosphate (8 to 10 g/ton): For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces)pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

    Ractopamine hydrochloride (9.8 to 24.6 g/ton) in combination with monensin USP (10 to 40 g/ton) and tylosin phosphate (8 to 10 g/ton): For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.


    Ractopamine hydrochloride top dress (not to exceed 800 g/ton) plus monensin USP (10 to 40 g/ton) in combination with tylosin phosphate (8 to 10 g/ton): For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter during the last 28 to 42 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes, and suppression of estrus (heat) in cattle (heifers) fed in confinement for slaughter for the last 28 to 42 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, and reduction of incidence of liver abscesses.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplement provides for: 1) component feeding of 60 mg zilpaterol hydrochloride/head/day in combination with feed containing monensin, USP; tylosin phosphate; and melengestrol acetate for increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes, and suppression of estrus (heat) in heifers fed in confinement for slaughter during the last 20 to 40 days on feed, and 2) adding the following statement to the labeling for the use of zilpaterol hydrochloride in complete feed when fed in combination with monensin, USP; tylosin phosphate; and melengestrol acetate: “CAUTION: Not to be fed to cattle in excess of 90 mg/head/day in complete feed. If pen consumption of complete feed exceeds 26.5 lb/head/day (90 percent dry matter basis), zilpaterol should not be fed in complete feed.”
  • Summary
    For increased rate of weight gain, increased carcass leanness, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes, and suppression of estrus (heat) in heifers fed in confinement for slaughter for the last 20 to 40 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 20 to 40 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes, and suppression of estrus (heat) in heifers fed in confinement for slaughter for the last 20 to 40 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplement provides for removal of the requirement of a pre-slaughter drug withdrawal period for heifers fed melengestrol acetate when melengestrol acetate is fed in combination either with lasalocid or with lasalocid and tylosin.
  • Summary
    For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), and reduced incidence of liver abscesses in heifers fed in confinement for slaughter.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For the prevention of coccidiosis caused by Eimeria bovis, and E. zuernii, for improved feed efficiency and for reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Actinomyces pyogenes in growing-finishing cattle being fed in confinement for slaughter.

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), for reduction of ammonia gas emissions per pound of live weight and hot carcass weight, and for the prevention and control of coccidiosis caused by Eimeria bovis and Eimeria zuernii, and for reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in growing beef heifers fed in confinement for slaughter during the last 14 to 91 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    BOVINE: indicated for use in the treatment of respiratory complex (shipping fever, pneumonia) usually associated with Pasteurella multocida and Corynebacterium pyogenes ; foot rot (necrotic pododermatitis) and calf diphtheria caused by Fusobacterium necrophorum and metritis caused by Corynebacterium pyogenes in beef cattle and nonlactating dairy cattle. SWINE: indicated for use in the treatment of arthritis caused by Mycoplasma hyosynoviae ; swine pneumonia caused by Pasteurella spp.; swine erysipelas caused by Erysipelothrix rhusiopathiae ; acute swine dysentery associated with Treponema hyodysenteriae when followed by appropriate medication in the drinking water and/or feed.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For increased rate of weight gain, improved feed efficiency, suppression of estrus heat), for reduction of ammonia gas emissions per pound of live weight and hot carcass weight, and for the prevention and control of coccidiosis caused by Eimeria bovis and Eimeria zuernii and for reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in growing beef heifers fed in confinement for slaughter during the last to 91 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    Ractopamine hydrochloride (4.5 to 9.0 g/ton) in combination with tylosin phosphate (40 or 100 g/ton): For increased rate of weight gain, improved feed efficiency and increased carcass leanness in finishing swine, weighing not less than 150 lbs, fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter; for control of swine dysentery associated with Brachyspira hyodysenteriae; and for control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis.


    Ractopamine hydrochloride (4.5 to 9.0 g/ton) in combination with tylosin phosphate (100 g/ton): For increased rate of weight gain, improved feed efficiency and increased carcass leanness in finishing swine, weighing not less than 150 lbs, fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter; and for control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis.


    Ractopamine hydrochloride (4.5 to 9.0 g/ton) in combination with tylosin phosphate (40 to 100 g/ton): For increased rate of weight gain, improved feed efficiency and increased carcass leanness in finishing swine, weighing not less than 150 lbs, fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter; for treatment and control of swine dysentery associated with Brachyspira hyodysenteriae; and for control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    Ractopamine hydrochloride (4.5 to 9.0 g/ton) in combination with tylosin phosphate 100 g/ton: For increased rate of weight gain, improved feed efficiency and increased carcass leanness in finishing swine, weighing not less than 150 lbs, fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter; and for control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis.

    Ractopamine hydrochloride (4.5 to 9.0 g/ton) in combination with tylosin phosphate (40 or 100 g/ton): For increased rate of weight gain, improved feed efficiency and increased carcass leanness in finishing swine, weighing not less than 150 lbs, fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter; for control of swine dysentery associated with Brachyspira hyodysenteriae; and for control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis.


    Ractopamine hydrochloride (4.5 to 9.0 g/ton) in combination with tylosin phosphate (40 to 100 g/ton): For increased rate of weight gain, improved feed efficiency and increased carcass leanness in finishing swine, weighing not less than 150 lbs, fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter; for treatment and control of swine dysentery associated with Brachyspira hyodysenteriae; and for control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis.

    

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplement provides for an increase in the upper dose limit of monensin to 480 mg/hd/day based upon the December 1, 2006, approval (N-095735-C-0297) for monensin, and to update the name of the tylosin targeted bacteria to Arcanobacterium pyogenes based on the November 7, 2006, approval (N-012491-C-0318) for tylosin phosphate, for increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), and prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii in heifers fed in confinement for slaughter.
  • Summary
    These supplements provide for the treatment of the approved combination of melengestrol acetate, monensin and tylosin to be treated as a combination under the provisions of the Animal Drug Availability Act of 1996, and its reference to feed delivered drug combinations. The effect is to provide for the addition of the coccidiosis claim for monensin (0.14 to 0.42 mg/lb body weight depending on the severity of the challenge, up to 360 mg/hd/day) and the addition of the complete tylosin dose range (60 to 90 mg/hd/day) to this combination with melengestrol acetate for heifers being fed in confinement for slaughter.
  • Summary

    This supplement provides for removal of the requirement of a pre-slaughter drug withdrawal period for heifers fed melengestrol acetate when melengestrol acetate is fed in combination with tylosin or with tylosin andmonensin. Previous approvals have required a 48 hour pre-slaughter drugwithdrawal for heifers fed melengestrol acetate when fed in combination with either tylosin or monensin and tylosin.

  • Summary
    For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), and reduced incidence of liver abscesses in heifers fed in confinement for slaughter.

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For reduction of ammonia gas emissions per pound of live weight and hot carcass weight, improved feed efficiency, and reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in beef steers and heifers fed in confinement for slaughter during the last 14 to 91 days on feed.

    For reduction of ammonia gas emissions per pound of live weight and hot carcass weight, prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii, and reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in beef steers and heifers fed in confinement for slaughter during the last 14 to 91 days on feed.


FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    1) For reduction of ammonia gas emissions per pound of live weight and hot carcass weight, prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii, and reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in beef steers and heifers fed in confinement for slaughter during the last 14 to 91 days on feed.

    2) For reduction of ammonia gas emissions per pound of live weight and hot carcass weight, improved feed efficiency, and reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in beef steers and heifers fed in confinement for slaughter during the last 14 to 91 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplement provides for addition to the labeling of the statements “A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal.” to the warning section and “Do not use in veal calves. Effectiveness and animal safety in veal calves have not been established.” immediately following the label indications.
  • Summary
    Component® E-S with Tylan®: For increased rate of weight gain and improved feed efficiency in steers weighing 400 lbs or more.
  • Summary

    This supplement provides for the deletion of the present labeling limitation against the use of Implus-C in heifer (suckling beef) calves intended for reproduction.

  • Summary

    This supplement provides for the use of CALF-oid in suckling beef calves (at least 45 days of age) up to 400 lbs. of bodyweight.

  • EA 110-315
  • FONSI 110-315

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplement provides for addition to the labeling of the statements “A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal.” to the warning section and “Do not use in veal calves. Effectiveness and animal safety in veal calves have not been established.” immediately following the label indications.
  • Summary

    For increased rate of weight gain and improved feed efficiency. The supplement provides for the use of a generic copy of Intervet, Inc.’s REVALOR-IS, a 4-pellet ear implant containing 80 mg trenbolone acetate and 16 mg estradiol.

  • Summary

    The supplement provides for the use of a generic copy of Intervet, Inc.’s REVALOR-IS, a 4-pellet ear implant containing 80 mg trenbolone acetate and 16 mg estradiol.

  • Summary
    This supplement provides for adding tylosin tartrate pellet as a local antibacterial to Component® TE-G
  • Summary
    For increased rate of weight gain in pasture cattle (slaughter, stocker, and feeder steers and heifers).
  • Summary
    This supplement provides for the addition of a tylosin tartrate pellet as a local antibacterial to Component® TE-S with Tylan®
  • Summary

    For increased rate of weight gain and improved feed efficiency in feedlot steers.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    Ractopamine hydrochloride 4.5 to 9.0 g/ton and tylosin phosphate 40 to 100 g/ton for 2 to 6 weeks immediately after medicating with 250 mg tylosin tartrate (as Tylan® Soluble) per gallon in drinking water for 3 to 10 days: For increased rate of weight gain, improved feed efficiency and increased carcass leanness in finishing swine, weighing not less than 150 lbs, fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter; for treatment and control of swine dysentery associated with Brachyspira hyodysenteriae; and for control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis.

    Ractopamine hydrochloride 4.5 to 9.0 g/ton and tylosin phosphate 100 g/ton for at least 3 weeks followed by 40 g/ton until market weight: For increased rate of weight gain, improved feed efficiency and increased carcass leanness in finishing swine, weighing not less than 150 lbs, fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter; for control of swine dysentery associated with Brachyspira hyodysenteriae; and for control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis.
    Ractopamine hydrochloride 4.5 to 9.0 g/ton and tylosin phosphate 100 g/ton: For increased rate of weight gain, improved feed efficiency and increased carcass leanness in finishing swine, weighing not less than 150 lbs, fed a complete ration containing at least 16% crude protein for the last 45 to 90 lbs of gain prior to slaughter; and for control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplement provides for the addition of a 29 mg tylosin tartrate pellet as a local antibacterial to COMPONENT TE-200 for use in steers and heifers fed in confinement for slaughter.
  • Summary
    This supplement provides for the addition of heifers to the label of Ivy Laboratories’ approved product COMPONENT TE-200 (trenbolone acetate and estradiol). The indications are for increased rate of weight gain and improved feed efficiency in steers and heifers fed in confinement for slaughter.
  • Summary
    This supplement provides for addition to the labeling of the statements “A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal.” to the warning section and “Do not use in veal calves. Effectiveness and animal safety in veal calves have not been established.” immediately following the label indications.
  • Summary
    This supplement provides for addition to the labeling of the statements “A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal.” to the warning section and “Do not use in veal calves. Effectiveness and animal safety in veal calves have not been established.” immediately following the label indications.
  • Summary

    For increased rate of weight gain.

  • Summary
    This submission for Component® TE-IH for heifers is a supplement to the original ANADA 200-346 for Component® TE-H. Component® TE-IH is a lower dose of Component® TE-H with each pellet in Component® TE-IH (total of 4 pellets) containing 20 mg trenbolone acetate and 2 mg estradiol in the same formulation as each pellet in Component® TE-H (total of 7 pellets).
  • Summary
    Component® TE-200 for steers is a supplement to the original ANADA 200-346 for Component® TE-H. Component® TE-200 is a higher dose of Component® TEH, with each pellet in Component® TE-200 (a total of 10 pellets) containing 20 mg trenbolone acetate and 2 mg estradiol in the same formulation as each pellet in Component® TE-H (total of 7 pellets).
  • Summary
    This supplement provides for the addition of a tylosin tartrate pellet as a local antibacterial to Component® TE-H.
  • Summary
    For Increased rate of weight gain and improved feed efficiency for heifers fed in confinement for slaughter.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplement provides for addition to the labeling of the statements “A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal.” to the warning section and “Do not use in veal calves. Effectiveness and animal safety in veal calves have not been established.” immediately following the label indications.
  • Summary
    This supplement provides for the addition of a tylosin tartrate pellet as a local antibacterial to Component® T-S and Component® T-H
  • Summary

    For improved feed efficiency in growing-finishing feedlot steers; for increased rate of weight gain and improved feed efficiency in growing-finishing feedlot heifers.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    This supplement provides for the addition of the indications and dosage and administration for the control of mortality caused by necrotic enteritis (NE) associated with Clostridium perfringens in broiler chickens.

  • Summary
    To add indications to the product label for swine to include: For the treatment and control of swine dysentery associated with Brachyspira hyodysenteriae when followed immediately by tylosin phosphate Type A medicated article in feed, and for the control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis when followed immediately by tylosin phosphate Type A medicated article in feed.
  • Summary

    Chickens: As an aid in the treatment of chronic respiratory disease (CRD) associated with Mycoplasma gallisepticum sensitive to tylosin in broiler and replacement chickens. For the control of CRD associated with Mycoplasma gallisepticum sensitive to tylosin at the time of vaccination or other stress in chickens. For the control of CRD associated with Mycoplasma synoviae sensitive to tylosin in broiler chickens.
    Turkeys: For maintaining weight gain and feed efficiency in the presence of infectious sinusitis associated with Mycoplasma gallisepticum sensitive to tylosin.
    Swine: For the treatment and control of swine dysentery associated with Brachypira hyodysenteriae.
    Honey Bees: For the control of American Foulbrood (Paenibacillus larvae).

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    Cattle (Beef and Non-lactating Dairy): Treatment of bovine respiratory complex (shipping fever, pneumonia) usually associated with Pasteurella multocida and Arcanobacterium pyogenes; foot rot (necrotic pododermatitis), and calf diphtheria cause by Fusobacterium necrophorum and metritis caused by Arcanobacterium pyogenes.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    This supplement provides for the addition of the following indication for use in chickens: “For control of mortality caused by NE associated with Clostridium perfringens in broiler chickens.”

  • Summary
    The effect of the supplement is to add new indications to the product labeling for swine to include: For the treatment and control of swine dysentery associated with Brachyspira hyodysenteriae when followed immediately by tylosin phosphate Type A medicated article in feed, and for the control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis when followed immediately by tylosin phosphate Type A medicated article in feed..
  • Summary

    Chickens: As an aid in the treatment of chronic respiratory disease (CRD) associated with Mycoplasma gallisepticum sensitive to tylosin in broiler and replacement chickens. For the control of chronic respiratory disease (CRD) associated with Mycoplasma gallisepticum sensitive to tylosin at time of vaccination or other stress in chickens. For the control of chronic respiratory disease (CRD) associated with Mycoplasma synoviae sensitive to tylosin in broiler chickens.
    Turkeys: For maintaining weight gain and feed efficiency in the presence of infectious sinusitis associated with Mycoplasma gallisepticum sensitive to tylosin.
    Swine: For the treatment and control of swine dysentery associated with Brachyspira hyodysenteriae.
    Honey Bees: For the control of American Foulbrood (Paenibaccillus larvae).

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    This supplemental approval provides for the addition of a 40 g/lb strength of this Type A medicated article.

  • Summary

    Beef cattle: For reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes.
    Chickens: For increased rate of weight gain and improved feed efficiency.
    Laying chickens: For improved feed efficiency.
    Broilers and replacement chickens: To aid in the control of chronic respiratory disease associated with Mycoplasma gallisepticum.
    Swine: For increased rate of weight gain and improved feed efficiency, for maintaining weight gains and feed efficiency in the presence of atrophic rhinitis, for control of swine dysentery associated with Brachyspira hyodysenteriae, for the treatment and control of swine dysentery associated with Brachyspira hyodysenteriae immediately after medicating with tylosin tartrate in drinking water, and for control of porcine proliferative enteropathies (ileitis) associated with Lawsonia intracellularis.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    provides for the treatment of the approved combination of monensin plus tylosin to be treated as a combination under the provisions of the Animal Drug Availability Act of 1996, and its reference to feed delivered drug combinations.
  • Summary
    provides for the complete range of both individually approved drugs (Type A Medicated Articles) in Type B or C medicated feeds in combination for cattle fed in confinement for slaughter.
  • Summary
    For improved feed efficiency and for reduction of incidence of liver abscesses in beef cattle caused by Sphaerophorus necrophorus and Corynebacterium pyogenes .
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For improved feed efficiency and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter.

    For prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For improved feed efficiency and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter.

    For prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium pyogenes in heifers fed in confinement for slaughter.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes, and suppression of estrus (heat) in heifers fed in confinement for slaughter for the last 28 to 42 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    1. For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.
    2. For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.
    3. For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes; and suppression of estrus (heat) in heifers fed in confinement for slaughter for the last 28 to 42 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    Increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium pyogenes in heifers fed in confinement for slaughter.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    Increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium pyogenes in heifers fed in confinement for slaughter.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat) and reduced incidence of liver abscesses caused by Fusobacterium necrophorum and Actinomyces (Corynebacterium) pyogenes in heifers being fed in confinement for slaughter.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed and for increased rate of weight gain, improved feed efficiency and suppression of estrus (heat).

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed and for increased rate of weight gain, improved feed efficiency and suppression of estrus (heat).

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For the prevention of coccidiosis caused by Eimeria bovis and E. zuernii, for improved feed efficiency, and for reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in cattle fed in confinement for slaughter.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For the prevention of coccidiosis caused by Eimeria bovis and E. zuernii, for improved feed efficiency, and for reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes in cattle fed in confinement for slaughter.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed and For increased rate of weight gain, improved feed efficiency and suppression of estrus (heat).

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed and for increased rate of weight gain, improved feed efficiency and suppression of estrus (heat).

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    1) For increased rate of weight gain and improved feed efficiency in cattle fed in confinement for slaughter during the last 28 to 42 days on feed; 2) for increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed; and 3) for increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    1) For increased rate of weight gain and improved feed efficiency in cattle fed in
    confinement for slaughter during the last 28 to 42 days on feed; 2) For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of
    incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed; and 3) For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    1) For increased rate of weight gain and improved feed efficiency in cattle fed in confinement for slaughter during the last 28 to 42 days on feed; 2) For increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed; and 3) For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    1) For increased rate of weight gain and improved feed efficiency in cattle fed in confinement for slaughter during the last 28 to 42 days on feed; 2) for increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed; and 3) for increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    This supplement provides for the establishment of a tolerance of 500 ppb for residues of tylosin in honey.

  • Summary
    This supplement provides for the addition of the indication for the control of mortality caused by necrotic enteritis (NE) associated with Clostridium perfringens in broiler chickens.
  • Summary
    This supplement provides for the approval of TYLAN Soluble (tylosin tartrate) followed by TYLAN Type A medicated article (tylosin phosphate) for the treatment and control of swine dysentery associated with Brachyspira hyodysenteriae in swine and the control of porcine proliferative enteropathies (PPE, ileitis) associated with Lawsonia intracellularis in swine.
  • Summary
    To add the indication for the control of American foulbrood (Paenibacillus larvae) in honey bees.
  • EA 013-076
  • FONSI 013-076
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    SWINE: For increased rate of weight gain and improved feed efficiency. For prevention of swine dysentery (vibrionic). For maintaining weight gains and feed efficiency in the presence of atrophic rhinitis. For the treatment and control of swine dysentery (vibrionic) following initial medication of Tylan Plus Vitamins in drinking water. BEEF CATTLE: For reduction in the incidence of liver abscesses caused by Sphaerophorus necrophorus and Corynebacterium pyogenes. CHICKENS: For increased rate of weight gain and improved feed efficiency. LAYING CHICKENS: Improving feed efficiency. BROILER AND REPLACEMENT CHICKENS: To aid in the control of chronic respiratory disease caused by Mycoplasma gallisepticum.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For increased rate of weight gain and improved feed efficiency, and as an aid in the prevention of coccidiosis caused by Eimeria tenella, E. necatrix, E. acervulina, E. maxima, E. brunetti, and E. mivati in broiler chickens.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For increased rate of weight gain and improved feed efficiency, and as an aid in the prevention of coccidiosis caused by Eimeria tenella, E. necatrix, E. acervulina, E. maxima, E. brunetti, and E. mivati in broiler chickens.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat) and reduced incidence of liver abscesses caused by Fusobacterium necrophorum and Actinomyces (Corynebacterium) pyogenes in heifers being fed in confinement for slaughter.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), and reduced incidence of liver abscesses in heifers fed in confinement for slaughter.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), and reduced incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in heifers fed in confinement for slaughter.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplement provides for: 1) component feeding of 60 mg zilpaterol hydrochloride/head/day in combination with feed containing monensin and tylosin phosphate for increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter during the last 20 to 40 days on feed, and 2) adding the following statement to the labeling for the use of zilpaterol hydrochloride in complete feed when fed in combination with monensin and tylosin phosphate: “CAUTION: Not to be fed to cattle in excess of 90 mg/head/day in complete feed. If pen consumption of complete feed exceeds 26.5 lb/head/day (90 percent dry matter basis), zilpaterol should not be fed in complete feed."
  • Summary
    For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter for the last 20 to 40 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplement provides for top dress application of ractopamine hydrochloride (OPTAFLEXX) Type C medicated feed administered on Type C medicated feeds containing monensin USP (RUMENSIN) and tylosin phosphate (TYLAN) for increased rate of weight gain, improved feed efficiency, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, and reduction in incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes in cattle fed in confinement for slaughter during the last 28 to 42 days on feed.
  • Summary
    This supplement provides for revised dosing for the combined use of ractopamine hydrochloride, monensin USP, and tylosin phosphate for cattle fed in confinement for slaughter, based on the December 1, 2006, supplemental approval for RUMENSIN (under NADA 095-735), which provided for an increase in the upper dosage limit in cattle being fed in confinement for slaughter. This supplement also updates the name of one of tylosin’s targeted bacteria to Arcanobacterium (Actinomyces) pyogenes, based on the November 7, 2006, supplemental approval for TYLAN (under NADA 012-491).
  • Summary
    Increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, and reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Actinomyces (Corynebacterium) pyogenes in cattle fed in confinement for slaughter for the last 28 to 42 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplement provides for revised dosing for the combined use of ractopamine hydrochloride, monensin USP, tylosin phosphate and melengestrol acetate for heifers fed in confinement for slaughter, based on the December 1, 2006, supplemental approval for RUMENSIN (under NADA 095-735), which provided for an increase in the upper dosage limit in cattle being fed in confinement for slaughter. This supplement also updates the name of one of tylosin’s targeted bacteria to Arcanobacterium (Actinomyces) pyogenes, based on the November 7, 2006, supplemental approval for TYLAN (under NADA 012-491). In addition, this supplement increases the monensin tolerance in cattle liver from 0.05 to 0.10 ppm.
  • Summary
    For increased rate of weight gain, improved feed efficiency, increased carcass leanness, prevention and control of coccidiosis due to Eimeria bovis and E. zuernii, reduction of incidence of liver abscesses caused by Fusobacterium necrophorum and Actinomyces (Corynebacterium) pyogenes, and suppression of estrus (heat) in heifers fed in confinement for slaughter for the last 28 to 42 days on feed.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For increased rate of weight gain and improved feed efficiency, and as an aid in the prevention of coccidiosis caused by Eimeria tenella, E. necatrix, E. acervulina, E. maxima, E. brunetti, and E. mivati in broiler chickens.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    This supplement provides for removal of the requirement of a pre-slaughter drug withdrawal period for heifers fed melengestrol acetate when melengestrol acetate is fed in combination either with lasalocid or with lasalocid and tylosin. Previous approvals have required a 48 hour pre-slaughter drug withdrawal for heifers fed melengestrol acetate when fed in combination with these drugs.

  • Summary
    For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat), and reduced incidence of liver abscesses in heifers fed in confinement for slaughter.

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    As an aid in the prevention of coccidiosis caused by Eimeria necatrix, E. tenella, E. acervulina, E. maxima, E. brunetti, and E. mivati, and for increased rate of weight gain and improved feed efficiency in broiler chickens.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For the prevention of coccidiosis caused by Eimeria necatrix, E. tenella, E. acervulina, E. brunetti, E. mivati, and E. maxima, for increased rate of weight gain and improved feed efficiency.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For increased rate of weight gain and improved feed efficiency, and as an aid in the prevention of coccidiosis caused by Eimeria tenella, E. necatrix, E. acervulina, E. maxima, E. brunette, and E. mivati in broiler chickens.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Usage

Maintaining weight gains and feed efficiency in the presence of atrophic rhinitis; lowering the incidence and severity of Bordetella bronchiseptica rhinitis; prevention of swine dysentery (vibrionic); control of swine pneumonias caused by bacterial pathogens (Pasteurella multocida and/or Corynebacterium pyogenes). Control of infestations of large roundworms (Ascaris suis), nodular worms Oesophagostomum dentatum), and whipworms (Trichuris suis); growth promotion and feed efficiency. For the reduction in severity of effects of infectious sinusitis associated with Mycoplasma gallisepticum .

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

As tylosin phosphate. Withdraw 15 days before slaughter. As tylosin phosphate. Feed continuously. Only medicated water should be available to the birds.

Side Effects

No approved side-effect narrative is linked yet.

openFDA reaction signals are available for Dog 26 and Cat 8 (view top reported reactions).

Top Reported Reactions (openFDA)

Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).

Dog
Digestive
Diarrhea (24) Vomiting (18) Decreased appetite (9)
Neurologic
Tiredness (lethargy) (10)
Effectiveness
Partial lack of efficacy (1) Partial lack of efficacy (1) Partial lack of efficacy (1) Partial lack of efficacy (1) Partial lack of efficacy (1) Partial lack of efficacy (1)
Other
Death by euthanasia (10) Other abnormal test result NOS (10) Not eating (9) Polydipsia (9) Cushings disease NOS (1) Cushings disease NOS (1) Cushings disease NOS (1) Cushings disease NOS (1) Cushings disease NOS (1) Cushings disease NOS (1) Intentional misuse (1) Intentional misuse (1) Intentional misuse (1) Intentional misuse (1) Intentional misuse (1) Intentional misuse (1)
Cat
Digestive
Diarrhea (3) Vomiting (2) Vomiting (1)
Behavior
Behavioral disorder (unspecified) (1)
Other
Loose stool (2) Blood in urine (1) Dehydration (1) Elevated blood urea nitrogen (1)

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, ['Terrier (unspecified)', 'Dog (unknown)'], Male, 14 year, 12.973 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Cushings disease NOS, Partial lack of efficacy, Intentional misuse • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055354
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 14.00 Year
  • Weight: 12.973 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Cushings disease NOS Partial lack of efficacy Intentional misuse
Outcomes: Ongoing

Dog, Terrier - Bull, Female, 9 year, 24.63 kilogram • Drug: MSK, Solution, Unknown • Reactions: Not eating, Soft stool, Difficulty to rise, Elevated temperature, Reluctant to move… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-046265
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 9.00 Year
  • Weight: 24.630 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Solution
Reactions Reported:
Not eating Soft stool Difficulty to rise Elevated temperature Reluctant to move Tremors Panting Skin and tissue infection NOS Leucopenia NOS Elevated serum alkaline phosphatase Urinary tract infection Abnormal cytology Vomiting Enlarged liver Lymphadenopathy Splenomegaly Hypoalbuminaemia
Outcomes: Ongoing

Dog, Terrier - Bull - American Pit, Female, 9 year, 24.63 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Not eating, Soft stool, Difficulty to rise, Elevated temperature, Reluctant to move… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-031344
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 9.00 Year
  • Weight: 24.630 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Not eating Soft stool Difficulty to rise Elevated temperature Reluctant to move Tremors Panting Skin and tissue infection NOS Leucopenia NOS Elevated serum alkaline phosphatase Urinary tract infection Abnormal cytology Vomiting Enlarged liver Lymphadenopathy Splenomegaly Hypoalbuminaemia
Outcomes: Ongoing

Dog, ['Dachshund (unspecified)', 'Hound - Basset'], Male, 13 year, 17.69 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Uncomfortable • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-043117
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 13.00 Year
  • Weight: 17.690 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Uncomfortable
Outcomes: Outcome Unknown

Cat, ['Domestic Mediumhair', 'Maine Coon'], Male, 11.5 year, 6.3 kilogram • Drug: MSK, Solution, Intramuscular, Dose: 0.10 mL per animal • Reactions: Soft stool, Blood in urine, Wound, Ketosis, Skin abscess… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-013615
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 11.50 Year
  • Weight: 6.300 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intramuscular
  • Form: Solution
  • Dose: 0.10 mL per animal
Reactions Reported:
Soft stool Blood in urine Wound Ketosis Skin abscess Glucosuria Elevated blood urea nitrogen Lack of efficacy - NOS Urine abnormalities NOS Weight fluctuation
Outcomes: Ongoing

Dog, Retriever - Golden, Male, 9 year, 36.605 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Seizure NOS, Tiredness (lethargy), Behavioral disorder (unspecified) • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-013312
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 9.00 Year
  • Weight: 36.605 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Seizure NOS Tiredness (lethargy) Behavioral disorder (unspecified)
Outcomes: Recovered/Normal

Cat, Himalayan, Male, 13 year, 7.11 kilogram • Drug: MSK, Capsule, Unknown, Dose: 125 Milligram per animal • Reactions: Loose stool, Small intestinal bacterial overgrowth • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2024-US-047376
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 13.00 Year
  • Weight: 7.110 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Capsule
  • Dose: 125 Milligram per animal
Reactions Reported:
Loose stool Small intestinal bacterial overgrowth
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 10.5 year, 7.6 kilogram • Drug: MSK, Solution, Unknown • Reactions: Diarrhea, Behavioral disorder (unspecified), Loose stool, Dehydration • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2024-US-031098
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 10.50 Year
  • Weight: 7.600 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Solution
Reactions Reported:
Diarrhea Behavioral disorder (unspecified) Loose stool Dehydration
Outcomes: Ongoing

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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