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Meds A-Z

Oxytetracycline

Detailed information about Oxytetracycline

Official label facts Owner quick guide first Marketing clearly labeled
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Pet Owner Quick Guide

Start here: what this medicine is for, what it does, and when it's usually needed.

Usually used for:

As an aid in the prevention of coccidiosis caused by Eimeria necatrix, E. tenella, E. acervulina, E. brunetti, E. mivati , and E. maxima ; and for the control of complicated chronic respiratory disease (CRD or air-sac in...

What it does:

It is used in dogs for the treatment of bacterial pneumonia caused by Brucella bronchiseptica, tonsillitis caused by Streptococcus hemolyticus, bacterial enteritis caused by Escherichia coli, urinary tract infections cau...

When it's needed:

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drink...

Call your vet sooner if you notice:

  • Federal law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption. Prepare a fresh solution daily. Administer up to 14 days. Do not use for more than 14 consecutive days. Use as a sole source of oxytetracycline. Zero-day slaughter withdrawal in swine.

Commonly reported reactions:

  • (2 reports)
  • (1 reports)
  • (1 reports)

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
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Oxytetracycline

Oxytetracycline

Drug type: Generic ingredient • Branded profile FDA branded products available

Species: Both

Manufacturer: Phibro Animal Health Corp.

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Phibro Animal Health Corp.
Form: Bolus, Capsule, Injectable Solution, Liquid (Solution), Medicated Feed, Ointment
Identifiers:
ANADA: 200008 ANADA: 200026 ANADA: 200066 ANADA: 200068 ANADA: 200096 ANADA: 200117 ANADA: 200123 ANADA: 200128 ANADA: 200144 ANADA: 200146 ANADA: 200154 ANADA: 200232 ANADA: 200247 ANADA: 200305 ANADA: 200306 ANADA: 200452 ANADA: 200460 ANADA: 200537 NADA: 101666 NADA: 103758
Source metadata:

Warnings / Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption. Prepare a fresh solution daily. Administer up to 14 days. Do not use for more than 14 consecutive days. Use as a sole source of oxytetracycline. Zero-day slaughter withdrawal in swine.

  • High: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption. Prepare a fresh solution daily. Administer up to 14 days. Do not use for more than 14 consecutive days. Use as a sole source of oxytetracycline. Zero-day slaughter withdrawal in swine.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
31
Serious reports
11
Species represented
2
Most Reported Reactions
Reaction Cases Species Serious cases
2 Cat, Dog 1
1 Cat 1
1 Cat 1
1 Dog 1
1 Cat 1
1 Dog 1
1 Cat 1
1 Cat 1

Species coverage: Cat (20) Dog (12)

View detailed reaction table
Reaction Species Seriousness Frequency Reports
Cat Non-serious - 1
Dog Non-serious - 1
Cat Non-serious - 1
Dog Non-serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Non-serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Non-serious - 1
Cat Non-serious - 1
Cat Non-serious - 1
Cat Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Cat Serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Serious - 1
Dog Non-serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Cat Non-serious - 1
Cat Non-serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Non-serious - 1
Cat Non-serious - 1
Cat Unknown - -
Source metadata:

Storage & Handling

No storage/handling guidance is linked yet.

Source metadata: No source yet.

Documents

Official label facts are separated from secondary summaries.

Official documents: 167 • Secondary summaries: 0

Official label facts
Secondary summaries

No source yet.

Promotional Materials (Marketing)

This content is marketing material and not clinical guidance.

No marketing assets are linked yet.

No source yet.

Source metadata: No source yet.
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Technical appendix (vet reference)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 9, 2026, 3:15 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:22 AM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: AGRIMYCIN® 200 AGRIMYCIN®-343 Aquachel 100 mg BOVATEC® and TM® Bio-Mycin® 200 Biocyl-50 Biocyl-100 Coban™/TM® Geomycin 200 Hexasol® Injection Liquamycin® Injectable Terramycin® Injectable Liquamycin® Intramuscular Liquamycin® LA-200® Liquimast Solution for Mastitis MAGNA-TERRAMYCIN® Soluble Powder MAXIM 100 MAXIM-200 MGA® (liquid) and TM® MGA® and TM® Mecadox® and Terramycin® Medamycin® 100 MEDAMYCIN® Neo-Oxy 50/50® Neo-Oxy 100/100 MR® Neo-Terramycin® 100/100 Neo-Terramycin® 50/50D Neo-Terramycin® 50/50 Neo-Terramycin® 100/100D Noromycin® 300 LA OXY 500 Calf Bolus OXY 1000 Calf Bolus OXY WS™ OXY-TET 50™ Bio-Mycin® OXYJECT® 100 Status™ SQ Oxy-Tet™ Injection Bio-Mycin C Oxyject® Oxytet 100 Oxytetracycline Hydrochloride Soluble Powder Oxytetracycline Injection Oxytetracycline Injection 200 Oxytetracycline Premix Oxytetracycline-50 Oxytet® Soluble OXYMarine™ Oxyvet-100 Aquachel-100 Pennox 343® Pennox® 200 Purina® Mix-R-Mycin Concentrate Rachelle Oxyvet Injection Sacox® / Terramycin® TERRAMYCIN-343® TERRAMYCIN® TERRAMYCIN® Soluble Powder Concentrate TM-50® TM-50® D TM-100® TM-100®D TM® plus Bio-Cox® TM® plus Robenz® TM®-10 Premix TM®-5 Antibiotic Feed Supplement Terra-Cortril Spray Liqua-Cortril Spray Terramycin® Terramycin® 10 Terramycin® 30 Terramycin® 50 Terramycin® 100 Terramycin® 200 Terramycin® 200 Granular Terramycin® 100MR Terramycin® 100 Liquamycin® 100 Terramycin® 100 for Fish Terramycin® 200 for Fish Terramycin® Egg Formula Terramycin® Premix Terramycin® Scours Tablets Terramycin® Vet Capsules Tetroxy® 25 Tetroxy® 343 Tetroxy® Aquatic Tetroxy® HCA-280 Tetroxy® HCA-1772 Tetroxy® HCA-1400 Tetroxy®-LA
Case-reported brands (openFDA): MSK
Catalog species: Both FDA-labeled species: Beef, Beef And Dairy, Beef And Non-Lactating Dairy, Beef and dairy calves, Beef calves, Beef fed In confinement for slaughter, Beef heifers fed in confinement for slaughter, Breeders not laying eggs for human consumption, Breeding, Broilers, Broilers not laying eggs for human consumption, Calves, Calves Up To 250 Pounds, Calves including preruminating (veal) calves, Cat, Catfish, Cattle, Chicken, Dairy, Dairy calves, Dog, Excluding turkeys producing eggs for human consumption, Fish, Freshwater-Reared Salmonids, Freshwater-reared salmonids weighing up to 55 grams, Growing, Honey Bees, Horse, Lobster, No Use Class Stated Or Implied, No use class stated or implied, Not laying eggs for human consumption, Pacific Salmon, Sheep, Sows, Sows with litters or about to farrow, Swine, Turkey
Rx/OTC: OTC, RX, RX/OTC, VFD
Form/route: Bolus, Capsule, Injectable Solution, Liquid (Solution), Medicated Feed, Ointment, Powder, Powder for solution, Soluble Powder, Solution, Spray, Tablet, Type A Medicated Article Immersion, Intramuscular, Intravenous, Ophthalmic, Oral, Subcutaneous, Topical
Applications: NADA 99006 • NADA 138-939 • NADA 94975 • NADA 140-579 • NADA 32946 • NADA 46719 • NADA 46718 • NADA 8622 • NADA 95143 • ANADA 200-537 • NADA 8763 • ANADA 200-117 • NADA 141-002 • ANADA 200-128 • NADA 113-232 • ANADA 200-306 • ANADA 200-123 • ANADA 200-154 • ANADA 200-068 • ANADA 200-008 • ANADA 200-452 • NADA 95642 • NADA 108-963 • NADA 45143 • NADA 97452 • NADA 47278 • NADA 38439 • ANADA 200-144 • NADA 141-143 • NADA 140-582 • NADA 48287 • NADA 91127 • NADA 99402 • NADA 94114 • NADA 11060 • NADA 141-312 • NADA 8804 • NADA 141-211 • NADA 130-435 • ANADA 200-146 • ANADA 200-247 • NADA 140-448 • NADA 101-666 • ANADA 200-096 • ANADA 200-460 • ANADA 200-066 • NADA 38200 • ANADA 200-026 • NADA 49948 • ANADA 200-232 • NADA 8769 • NADA 13146 • NADA 11034 • ANADA 200-305 • NADA 94959 • NADA 94960 • NADA 13293 • NADA 10661 • NADA 103-758 • NADA 7879 • NADA 13470 • NADA 8696
Documents: 76 (FOI: 68) • SPL: 91 Label highlights Official documents
Safety (openFDA)
Top reactions: Dog 8 Cat 8 View
Case summaries: 8 (showing 8) View
openFDA reports are unverified and do not prove causation.

Explore
Linked using: Fda_Label (0.95), Fda_Label (0.95), Fda_Label (0.95)

Diagnosis Codes
ICD10_CM: A27.9
Leptospirosis, unspecified

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Federal law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption. Prepare a fresh solution daily. Administer up to 14 days. Do not use for more than 14 consecutive days. Use as a sole source of oxytetracycline. Zero-day slaughter withdrawal in swine. (Contraindication, High)
Top reaction signals
Abnormal pupil light reflex (1) Anal sac disorder (1) Ataxia (1) Behavioural disorder NOS (1) Behavioural disorder NOS (1) Constipation (1) Corneal ulcer (1) Death by euthanasia (1) Decreased appetite (1) Decreased bowel movements (1) Dilated pupils (1) Ear infection NOS (1) Head shake - ear disorder (1) Head tilt - neurological disorder (see also Head tilt - ear disorder) (1) Hives (see also 'Skin') (1) Injection site pain (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
ANADA: 200008 ANADA: 200026 ANADA: 200066 ANADA: 200068 ANADA: 200096 ANADA: 200117 ANADA: 200123 ANADA: 200128 ANADA: 200144 ANADA: 200146 ANADA: 200154 ANADA: 200232 ANADA: 200247 ANADA: 200305 ANADA: 200306 ANADA: 200452 ANADA: 200460 ANADA: 200537 NADA: 101666 NADA: 103758 NADA: 10661 NADA: 108963 NADA: 11034 NADA: 11060
Package NDC Product NDC Form / Route Status
0010-4753-01 0010 -
0010-4753-02 0010 -
0010-4753-03 0010 -
13985-035-02 13985 -
13985-035-04 13985 -
13985-035-05 13985 -
13985-944-10 13985 -
13985-944-25 13985 -
13985-944-50 13985 -
23243-6759-1 23243 -
23243-6759-2 23243 -
23243-6759-3 23243 -
23243-7430-4 23243 -
23243-7430-5 23243 -
23243-7430-6 23243 -
43457-528-25 43457 -
46066-007-02 46066 -
46066-007-04 46066 -
46066-007-05 46066 -
46066-553-03 46066 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

Data Sources & Revision History

Every non-trivial field is expected to include provenance and update timestamps.

Official 71 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used f… (Official, 2026-02-12)
  • side_effects: Top reported reactions (openFDA): Anal sac disorder, Behavioural disorder NOS, Corneal ulcer, Hives (see also 'Skin'), Injection site pain, Leucocytosis NOS. (Official, 2026-02-12)
  • usage: It is used in dogs for the treatment of bacterial pneumonia caused by Brucella bronchiseptica, tonsillitis caused by Streptococcus hemolyticus, bacterial enter… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Coban™/TM®
VFD
Monensin Oxytetracycline
Type A Medicated Article Oral
Phibro Animal Health Corp. NADA 99006 Approved Nov 5, 2025
Neo-Oxy 50/50® Neo-Oxy 100/100 MR®
VFD
Neomycin Sulfate Oxytetracycline Hydrochloride
Type A Medicated Article Oral
Pharmgate Inc. NADA 138-939 Approved Oct 15, 2025
Neo-Terramycin® 100/100 Neo-Terramycin® 50/50D Neo-Terramycin® 50/50 Neo-Terramycin® 100/100D
VFD
Neomycin Sulfate Oxytetracycline
Oral
Phibro Animal Health Corp. NADA 94975 Approved Jan 16, 2025
BOVATEC® and TM®
VFD
Lasalocid Oxytetracycline (Monoalkyl Trimethyl Ammonium Salt)
Type A Medicated Article Oral
Phibro Animal Health Corp. NADA 140-579 Approved Nov 12, 2024
MAGNA-TERRAMYCIN® Soluble Powder
RX
Carbomycin Oxytetracycline Hydrochloride
Soluble Powder Oral
Phibro Animal Health Corp. NADA 32946 Approved Nov 12, 2024
MGA® and TM®
VFD
Melengestrol Acetate Oxytetracycline
Type A Medicated Article Oral
Phibro Animal Health Corp. NADA 46719 Approved Nov 12, 2024
MGA® (liquid) and TM®
VFD
Melengestrol Acetate Oxytetracycline
Type A Medicated Article Oral
Phibro Animal Health Corp. NADA 46718 Approved Nov 12, 2024
TERRAMYCIN-343® TERRAMYCIN® TERRAMYCIN® Soluble Powder Concentrate
RX
Oxytetracycline Hydrochloride
Powder for solution Oral, Immersion
Phibro Animal Health Corp. NADA 8622 Approved Nov 12, 2024
Terramycin® 10 Terramycin® 30 Terramycin® 50 Terramycin® 100 Terramycin® 200 Terramycin® 200 Granular Terramycin® 100MR
VFD
Oxytetracycline
Type A Medicated Article Oral
Phibro Animal Health Corp. NADA 95143 Approved Aug 21, 2024
Tetroxy®-LA
RX
Oxytetracycline
Injectable Solution Intramuscular, Intravenous, Subcutaneous
Bimeda Animal Health Limited ANADA 200-537 Approved Jul 3, 2024
Terramycin®
RX
Oxytetracycline Hydrochloride Polymyxin B Sulfate
Ointment Ophthalmic
Zoetis Inc. NADA 8763 Approved Jul 1, 2024
Oxytetracycline Injection
RX
Oxytetracycline
Injectable Solution Intravenous, Intramuscular
Bimeda Animal Health Limited ANADA 200-117 Approved Apr 30, 2024
OXY 500 Calf Bolus OXY 1000 Calf Bolus
OTC
Oxytetracycline Hydrochloride
Bolus Oral
Boehringer lngelheim Animal Health USA Inc. NADA 141-002 W Aug 25, 2023
AGRIMYCIN® 200
RX
Oxytetracycline Dihydrate
Injectable Solution Intravenous, Subcutaneous, Intramuscular
Huvepharma EOOD ANADA 200-128 Approved Jun 15, 2023
Liquamycin® LA-200®
RX
Oxytetracycline
Injectable Solution Subcutaneous, Intravenous, Intramuscular
Zoetis Inc. NADA 113-232 Approved Jun 15, 2023
Oxytetracycline Injection 200
RX
Oxytetracycline
Injectable Solution Subcutaneous, Intravenous, Intramuscular
Norbrook Laboratories, Ltd. ANADA 200-306 Approved Jun 14, 2023
MAXIM-200
RX
Oxytetracycline
Injectable Solution Subcutaneous, Intravenous, Intramuscular
Huvepharma EOOD ANADA 200-123 Approved Jun 12, 2023
Pennox® 200
RX
Oxytetracycline
Injectable Solution Intravenous, Subcutaneous, Intramuscular
Pharmgate Inc. ANADA 200-154 Approved Jun 7, 2023
MAXIM 100
RX
Oxytetracycline
Injectable Solution Intravenous
Huvepharma EOOD ANADA 200-068 Approved May 26, 2023
Bio-Mycin® 200
RX
Oxytetracycline
Injectable Solution Subcutaneous, Intramuscular, Intravenous
Boehringer lngelheim Animal Health USA, Inc. ANADA 200-008 Approved May 24, 2023
Oxytet 100
RX
Oxytetracycline
Injectable Solution Intravenous
Norbrook Laboratories, Ltd. ANADA 200-452 Approved May 23, 2023
Oxy-Tet™ Injection Bio-Mycin C
RX/OTC
Oxytetracycline Hydrochloride
Liquid (Solution) Intramuscular
Boehringer lngelheim Animal Health USA Inc. NADA 95642 W May 3, 2023
Medamycin® 100 MEDAMYCIN®
RX
Oxytetracycline
Injectable Solution Intramuscular
Cronus Pharma Specialities India Private Ltd. NADA 108-963 Approved May 1, 2023
Oxyject®
RX
Oxytetracycline
Injectable Solution Intramuscular
Cronus Pharma Specialities India Private Ltd. NADA 45143 Approved May 1, 2023
OXYJECT® 100 Status™ SQ
RX
Oxytetracycline
Injectable Solution Intramuscular
Cronus Pharma Specialities India Private Ltd. NADA 97452 Approved May 1, 2023
OXY-TET 50™ Bio-Mycin®
RX
Oxytetracycline
Injectable Solution Intramuscular, Intravenous
Cronus Pharma Specialities India Private Ltd. NADA 47278 Approved May 1, 2023
Terramycin® 100 for Fish Terramycin® 200 for Fish
VFD
Oxytetracycline Dihydrate
Type A Medicated Article Oral
Phibro Animal Health Corp. NADA 38439 Approved May 1, 2023
Tetroxy® HCA-280 Tetroxy® HCA-1772 Tetroxy® HCA-1400
RX
Oxytetracycline Hydrochloride
Soluble Powder Oral
Bimeda Animal Health Limited ANADA 200-144 Approved Jan 12, 2023
Noromycin® 300 LA
RX
Oxytetracycline Dihydrate
Solution Intravenous, Subcutaneous, Intramuscular
Norbrook Laboratories, Ltd. NADA 141-143 Approved Nov 18, 2022
Biocyl-50 Biocyl-100
RX
Oxytetracycline Hydrochloride
Injectable Solution Intravenous
Bimeda Animal Health Limited NADA 140-582 Approved Nov 16, 2022
Oxytetracycline-50
RX
Oxytetracycline Hydrochloride
Liquid (Solution) Intramuscular
Huvepharma EOOD NADA 48287 Approved Sep 26, 2022
Rachelle Oxyvet Injection
RX
Oxytetracycline Hydrochloride
Liquid (Solution) Intravenous, Intramuscular
Zoetis Inc. NADA 91127 Approved Sep 26, 2022
Oxyvet-100 Aquachel-100
RX
Oxytetracycline Hydrochloride
Liquid (Solution) Intravenous
Zoetis Inc. NADA 99402 Approved Aug 15, 2022
Terramycin® 100 Liquamycin® 100
RX
Oxytetracycline Hydrochloride
Liquid (Solution) Intramuscular
Zoetis Inc. NADA 94114 Approved Jul 29, 2022
Terramycin® Scours Tablets
RX
Oxytetracycline Hydrochloride
Tablet Oral
Zoetis Inc. NADA 11060 Approved Jul 29, 2022
Hexasol® Injection
RX
Flunixin Meglumine Oxytetracycline
Liquid (Solution) Intramuscular, Subcutaneous
Norbrook Laboratories, Ltd. NADA 141-312 Approved Mar 4, 2022
TM-50® TM-50® D TM-100® TM-100®D
VFD
Oxytetracycline Hydrochloride
Type A Medicated Article Oral
Phibro Animal Health Corp. NADA 8804 Approved Jul 13, 2021
Mecadox® and Terramycin®
VFD
Carbadox Oxytetracycline
Type A Medicated Article Oral
Phibro Animal Health Corp. NADA 141-211 Approved Aug 17, 2020
Oxytet® Soluble OXYMarine™
RX
Oxytetracycline Hydrochloride
Soluble Powder Immersion
Huvepharma EOOD NADA 130-435 Approved Jun 12, 2019
Tetroxy® 25
RX
Oxytetracycline Hydrochloride
Soluble Powder Oral
Bimeda Animal Health Limited ANADA 200-146 Approved Mar 17, 2019
Tetroxy® 343
RX
Oxytetracycline Hydrochloride
Powder Oral, Immersion
Bimeda Animal Health Limited ANADA 200-247 Approved Mar 17, 2019
TM® plus Bio-Cox®
VFD
Oxytetracycline Salinomycin Sodium
Type A Medicated Article Oral
Phibro Animal Health Corp. NADA 140-448 Approved Dec 18, 2018
TM® plus Robenz®
VFD
Oxytetracycline Robenidine Hydrochloride
Type A Medicated Article Oral
Phibro Animal Health Corp. NADA 101-666 Approved Dec 18, 2018
Sacox® / Terramycin®
VFD
Oxytetracycline Salinomycin Sodium
Type A Medicated Article Oral
Huvepharma EOOD ANADA 200-096 Approved Oct 22, 2018
Tetroxy® Aquatic
RX
Oxytetracycline Hydrochloride
Liquid (Solution) Immersion
Bimeda Animal Health Limited ANADA 200-460 Approved Oct 2, 2018
AGRIMYCIN®-343
RX
Oxytetracycline Hydrochloride
Soluble Powder Oral
Huvepharma EOOD ANADA 200-066 Approved Jul 2, 2018
OXY WS™
RX
Oxytetracycline Hydrochloride
Soluble Powder Oral
Phibro Animal Health Corp. NADA 38200 Approved May 15, 2017
Pennox 343®
RX
Oxytetracycline Hydrochloride
Soluble Powder Immersion, Oral
Pharmgate Inc. ANADA 200-026 Approved Jan 3, 2017
Aquachel 100 mg
RX
Lidocaine Oxytetracycline Hydrochloride
Liquid (Solution) Intramuscular
Zoetis Inc. NADA 49948 Approved Jun 1, 2016
Geomycin 200
OTC
Oxytetracycline
Liquid (Solution) Subcutaneous, Intramuscular, Intravenous
Pliva, d. d. ANADA 200-232 W Jun 1, 2016
Liquamycin® Injectable Terramycin® Injectable
RX
Oxytetracycline Hydrochloride
Liquid (Solution) Intravenous, Intramuscular, Subcutaneous
Zoetis Inc. NADA 8769 Approved Jun 1, 2016
Liquamycin® Intramuscular
RX
Lidocaine Oxytetracycline Hydrochloride
Liquid (Solution) Intramuscular
Zoetis Inc. NADA 13146 Approved Jun 1, 2016
Liquimast Solution for Mastitis
OTC
Oxytetracycline Hydrochloride
Pfizer, Inc. NADA 11034 W Jun 1, 2016
Oxytetracycline Hydrochloride Soluble Powder
OTC
Oxytetracycline Hydrochloride
Liquid (Solution) Oral
Vetoquinol N.-A., Inc. ANADA 200-305 W Jun 1, 2016
Oxytetracycline Premix
OTC
Oxytetracycline Hydrochloride
Purina Mills, Inc. NADA 94959 W Jun 1, 2016
Purina® Mix-R-Mycin Concentrate
OTC
Oxytetracycline Hydrochloride
Purina Mills, Inc. NADA 94960 W Jun 1, 2016
Terra-Cortril Spray Liqua-Cortril Spray
RX
Hydrocortisone Oxytetracycline Hydrochloride
Spray Topical
Zoetis Inc. NADA 13293 Approved Jun 1, 2016
Terramycin® Egg Formula
OTC
Oxytetracycline Hydrochloride
Pfizer, Inc. NADA 10661 W Jun 1, 2016
Terramycin® Premix
OTC
Oxytetracycline Hydrochloride
Medicated Feed Oral
Pfizer, Inc. NADA 103-758 W Jun 1, 2016
Terramycin® Vet Capsules
RX
Oxytetracycline Hydrochloride
Capsule Oral
Zoetis Inc. NADA 7879 Approved Jun 1, 2016
TM®-10 Premix
OTC
Oxytetracycline Hydrochloride
Pfizer, Inc. NADA 13470 W Jun 1, 2016
TM®-5 Antibiotic Feed Supplement
OTC
Oxytetracycline (Monoalkyl Trimethyl Ammonium Salt)
Pfizer, Inc. NADA 8696 W Jun 1, 2016

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Broilers
Composition / specifications
Type A medicated article containing 45 or 60 grams per pound monensin. Type A medicated article containing 100 grams per pound oxytetracycline (from oxytetracycline quaternary salt).
Chickens (broilers)
Indication

As an aid in the prevention of coccidiosis caused by Eimeria necatrix, E. tenella, E. acervulina, E. brunetti, E. mivati, and E. maxima; and for the control of complicated chronic respiratory disease (CRD or air-sac infection) caused by Mycoplasma gallisepticum and Escherichia coli in broiler chickens.

Dosage

90 or 110 grams monensin and 200 grams oxytetracycline per ton of Type C medicated feed.

Limitations

Feed continuously as sole ration. Withdraw 72 hours before slaughter. Do not feed to laying chickens. Do not feed to chickens over 16 weeks of age. Do not use in low-calcium feed containing less than 0.55% dietary calcium. Use in such feeds may result in violative residues. Do not allow horses other equines, mature turkeys, or guinea fowl access to feed containing monensin. Ingestion of monensin by horses andguinea fowl has been fatal. In the absence of coccidiosis in broiler chickens, use of monensin with no withdrawal period may limit feed intake, resulting in reduced weight gain. Not for replacement chickens intended to become breeding chickens.

Indication

As an aid in the prevention of coccidiosis caused by Eimeria necatrix, E. tenella, E. acervulina, E. brunetti, E. mivati, and E. maxima; and as an aid in the reduction of mortality due to air-sacculitis (air-sac infection) caused by Escherichia coli sensitive to oxytetracycline in broiler chickens.

Dosage

90 to 110 grams monensin and 500 grams oxytetracycline per ton of Type C medicated feed.

Limitations

Feed for 5 days as the sole ration. Treat at first clinical signs of disease. Withdraw 72 hours before slaughter. Do not feed to laying chickens. Do not feed to chickens over 16 weeks of age. Do not use in low-calcium feed containing less than 0.55% dietary calcium. Use in such feeds may result in violative residues. Do not allow horses other equines, mature turkeys, or guinea fowl access to feed containing monensin. Ingestion of monensin by horses and guinea fowl has been fatal. In the absence of cocciodiosis in broiler chickens, use of monensin with no withdrawal period may limit feed intake, resulting in reduced weight gain. Not for replacement chickens intended to become breeding chickens.

FDA page: Open in Animal Drugs @ FDA

Species: Breeding • No use class stated or implied • Calves Up To 250 Pounds • Growing, Over 400 Pounds • Beef And Non-Lactating Dairy • Calves, 250 to 400 pounds, excluding veal • Growing • No use class stated or implied • No use class stated or implied • Sheep, No Use Class Stated Or Implied
Composition / specifications
Type A medicated articles containing oxytetracycline equivalent to 50 grams per pound (g/lb) oxytetracycline hydrochloride and 50 g/lb neomycin sulfate or oxytetracycline equivalent to 100 g/lb oxytetracycline hydrochloride and 100 g/lb neomycin sulfate.
Chickens
Indication

For control of chronic respiratory disease (CRD) and air sac infection caused by Mycoplasma gallisepticum and Escherichia coli susceptible to oxytetracycline.

Dosage

400 g/ton

Limitations

Feed continuously for 7-14 days; do not feed to chickens producing eggs for human consumption; in low calcium feed, withdraw 3 days before slaughter.

Indication

For reduction of mortality due to air sacculitis (air sac infection) caused by Escherichia coli susceptible to oxytetracycline.

Dosage

500 g/ton

Limitations

Feed continuously for 5 days; do not feed to chickens producing eggs for human consumption; withdraw 24 hours before slaughter; in low calcium feed, withdraw 3 days before slaughter.

Indication

For control of infectious synovitis caused by Mycoplasma synoviae, control of fowl cholera caused by Pasteurella multocida susceptible to oxytetracycline.

Dosage

100 to 200 g/ton

Limitations

Feed continuously for 7-14 days; do not feed to chickens producing eggs for human consumption; in low calcium feed, withdraw 3 days before slaughter.

Turkeys
Indication

For control of complicating bacterial organisms associated with bluecomb (transmissible enteritis, coronaviral enteritis) susceptible to oxytetracycline.

Dosage

25 mg/lb body weight/day

Limitations

Feed continuously for 7 to 14 days; withdraw 5 days before slaughter; do not feed to turkeys producing eggs for human consumption.

Indication

For control of hexamitiasis caused by Hexamita meleagridis susceptible to oxytetracycline.

Dosage

100 g/ton

Limitations

Feed continuously for 7 to 14 days; do not feed to turkeys producing eggs for human consumption.

Indication

For control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.

Dosage

200 g/ton

Limitations

Feed continuously for 7 to 14 days; withdraw 5 days before slaughter; do not feed to turkeys producing eggs for human consumption.

Swine
Indication

For treatment of bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis and treatment of bacterial pneumonia caused by Pasteurella multocida susceptible to oxytetracycline; treatment and control of colibacillosis (bacterial enteritis) caused by Escherichia coli susceptible to neomycin.

Dosage

10 mg/lb/body weight/day

Limitations

Feed continuously for 7 to 14 days; withdraw 5 days before slaughter.

Swine (breeding)
Indication

For control and treatment of leptospirosis (reducing the incidence of abortion and shedding of leptospirae) caused by Leptospira Pomona susceptible to oxytetracycline.

Dosage

10 mg/lb/body weight/day

Limitations

Feed continuously for not more than 14 days; withdraw 5 days before slaughter.

Sheep
Indication

For treatment of bacterial enteritis caused by Escherichia coli and bacterial pneumonia caused by Pasteurella multocida susceptible to oxytetracycline; treatment and control of colibacillosis (bacterial enteritis) caused by Escherichia coli susceptible to neomycin.

Dosage

10 mg/lb body weight/day

Limitations

Feed continuously for 7-14 days. Treatment should continue 24 to 48 hours beyond remission of disease symptoms. Withdraw 5 days before slaughter.

Cattle (calves up to 250 lbs)
Indication

For treatment of bacterial enteritis caused by Escherichia coli susceptible to oxytetracycline; treatment and control of colibacillosis (bacterial enteritis) caused by Escherichia coli susceptible to neomycin.

Dosage

10 mg/lb body weight/day

Limitations

Feed continuously for 7 to 14 days; in milk replacers or starter feed. Treatment should continue 24 to 48 hours beyond remission of disease symptoms. A withdrawal period has not been established for use in pre-ruminating calves. Do not use in calves to be processed for veal.

Growing cattle (over 400 lbs)
Indication

For the reduction of the incidence of liver abscesses.

Dosage

75 mg/head/day

Limitations

Feed continuously.

Cattle
Indication

For the prevention and treatment of the early stages of shipping fever complex.

Dosage

0.5 to 2.0 g/head/day

Limitations

Feed 3-5 days before and after arrival in feedlots. A withdrawal period has not been established for use in pre-ruminating calves. Do not use in calves to be processed for veal. A milk discard time has not been established for use in lactating dairy cattle. Do not use in female dairy cattle 20 months of age or older.

Cattle (calves and beef and nonlactating dairy cattle)
Indication

For treatment of bacterial enteritis caused by Escherichia coli and bacterial pneumonia (shipping fever complex) caused by Pasteurella multocida susceptible to oxytetracycline; treatment and control of colibacillosis (bacterial enteritis) caused by Escherichia coli susceptible to neomycin.

Dosage

10 mg/lb body weight/day

Limitations

Feed continuously for 7-14 days in feed or milk replacers. Treatment should continue 24 to 48 hours beyond remission of disease symptoms. A withdrawal period has not been established for use in pre-ruminating calves. Do not use in calves to be processed for veal. A milk discard time has not been established for use in lactating dairy cattle. Do not use in female dairy cattle 20 months of age or older. Withdraw 5 days before slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Breeding • No use class stated or implied • Beef • Calves • Dairy, non-lactating • Not laying eggs for human consumption • Excluding turkeys producing eggs for human consumption • Sheep, No Use Class Stated Or Implied
Composition / specifications
oxytetracycline equivalent to 50 g [or 100 g] oxytetracycline hydrochloride /lb and
50 g [or 100 g] neomycin sulfate /lb
Chickens
Indication
Control of infectious synovitis caused by Mycoplasma synoviae; control of fowl cholera caused by Pasteurella multocida susceptible to oxytetracycline
Dosage
100-200 g/ton
Limitations

Feed continuously for 7 to 14 days. Do not feed to chickens producing eggs for human consumption. In low calcium feed, withdraw 3 days before slaughter. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Indication

For reduction of mortality due to air sacculitis (air sac infection) caused by E. coli susceptible to oxytetracycline.

Dosage

500 g/ton

Limitations

Feed continuously for 5 days. Do not feed to chickens producing eggs for human consumption. Withdraw 24 hours before slaughter. In low calcium feed, withdraw 3 days before slaughter. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Indication

For control of chronic respiratory disease (CRD) and air sac infection caused by M. gallisepticum and Escherichia coli susceptible to oxytetracycline.

Dosage

400 g/ton

Limitations

Feed continuously for 7 to 14 days. Do not feed to chickens producing eggs for human consumption. In low calcium feed, withdraw 3 days before slaughter. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Turkeys
Indication
Control of complicating bacterial organisms associated with bluecomb (transmissible enteritis, coronaviral enteritis) susceptible to oxytetracycline
Dosage
25 mg/lb of body weight daily
Limitations

Feed continuously for 7 to 14 days. Withdraw 5 days before slaughter. Do not feed to turkeys producing eggs for human consumption. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Indication
Control of hexamitiasis caused by Hexamita meleagridis susceptible to oxytetracycline
Dosage
100 g/ton
Limitations

Feed continuously for 7 to 14 days. Do not feed to turkeys producing eggs for human consumption. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Indication
Control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline
Dosage
200 g/ton
Limitations

Feed continuously for 7 to 14 days. Withdraw 5 days before slaughter. Do not feed to turkeys producing eggs for human consumption. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Swine
Indication

Treatment of bacterial enteritis caused by E. coli and Salmonella choleraesuis susceptible to oxytetracycline and treatment of bacterial pneumonia caused by Pasteurella multocida susceptible to oxytetracycline; treatment and control of colibacillosis (bacterial enteritis) caused by E. coli susceptible to neomycin.

Dosage

10 mg/lb of body weight daily. 

Limitations

Feed continuously for 7-14 days. 5-day withdrawal before slaughter. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Breeding Swine
Indication

For breeding swine for control and treatment of Leptospirosis (reducing the incidence of abortion and shedding of leptospirae) caused by Leptospira pomona susceptible to oxytetracycline

Dosage
10 mg/lb of body weight daily
Limitations

Feed continuously for not more than 14 days. Withdraw 5 days before slaughter. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Sheep
Indication

Treatment of bacterial enteritis caused by E. coli and bacterial pneumonia caused by Pasteurella multocida susceptible to oxytetracycline; treatment and control of colibacillosis (bacterial enteritis) caused by E. coli susceptible to neomycin.

Dosage

10 mg/lb of body weight daily

Limitations

Feed continuously for 7-14 days. Treatment should continue 24 to 48 hours beyond remission of disease symptoms. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Calves (Up to 250 Lbs)
Indication
For treatment of bacterial enteritis caused by E. coli susceptible to oxytetracycline; treatment and control of colibacillosis (bacterial enteritis) caused by E. coli susceptible to neomycin
Dosage
10 mg/lb of body weight daily
Limitations

Feed continuously for 7 to 14 days. Treatment should continue 24 to 48 hours beyond remission of disease symptoms. A withdrawal period has not been established for use in preruminating calves. Do not use in calves to be processed for veal. A milk discard time has not been established for use in lactating dairy cattle. Do not use in female dairy cattle 20 months of age or older. Withdraw 5 days before slaughter. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Growing Cattle (Over 400 Lbs)
Indication

For reduction of liver condemnation due to liver abscesses.

Dosage
75 mg/head/day
Limitations

Feed continuously. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Calves, Beef Cattle, and Non-Lactating Dairy
Indication

Calves and beef and non-lactating dairy cattle: For treatment of bacterial enteritis caused by E. coli and bacterial pneumonia (shipping fever complex) caused by P. multocida susceptible to oxytetracycline; treatment and control of colibacillosis (bacterial enteritis) caused by E. coli susceptible to neomycin.

Dosage

10 mg/lb body weight (BW)

Limitations

Feed continuously for 7 to 14 days. Treatment should continue 24 to 48 hours beyond remission of disease symptoms. A withdrawal period has not been established for use in preruminating calves. Do not use in calves to be processed for veal. A milk discard time has not been established for use in lactating dairy cattle. Do not use in female dairy cattle 20 months of age or older. Withdraw 5 days before slaughter. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Cattle
Indication

For prevention and treatment of the early stages of shipping fever complex.

Dosage

0.5 to 2.0 g/head/day

Limitations

Feed 3 to 5 days before and after arrival in feedlots. A withdrawal period has not been established for use in preruminating calves. Do not use in calves to be processed for veal. A milk discard time has not been established for use in lactating dairy cattle. Do not use in female dairy cattle 20 months of age or older. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Beef fed In confinement for slaughter
Composition / specifications
Type A medicated article containing 68, 91, or 150 grams of lasalocid (as lasalocid sodium) per pound or Type A liquid medicated article containing 90.7 grams of lasalocid (as lasalocid sodium) per pound. Type A medicated article containing 50 or 100 grams of oxytetracycline per pound.
Cattle (Beef, Fed in Confinement for Slaughter)
Indication

For improved feed efficiency and for the reduction of incidence of liver abscesses in cattle fed in confinement for slaughter.

Dosage

Feed continuously 10 to 30 g/ton lasalocid to provide 100 to 360 mg lasalocid per head per day and 7.5 g/ton oxytetracycline to provide 75 mg oxytetracycline per head per day.

Limitations

The safety of lasalocid in unapproved species has not been established. Do not allow horses or other equines access to feeds containing lasalocid. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

Indication

For increased rate of weight gain, improved feed efficiency, and for the reduction of incidence of liver abscesses in cattle fed in confinement for slaughter.

Dosage

Feed continuously 25 to 30 g/ton lasalocid to provide 250 to 360 mg lasalocid per head per day and 7.5 g/ton oxytetracycline to provide 75 mg oxytetracycline per head per day.

Limitations

The safety of lasalocid in unapproved species has not been established. Do not allow horses or other equines access to feeds containing lasalocid.

FDA page: Open in Animal Drugs @ FDA

Species: Not laying eggs for human consumption
Composition / specifications
Each pound contains 51.2 grams oxytetracycline HCl and 51.2 grams carbomycin base.
Chickens
Indication

As an aid in the prevention and treatment of complicated chronic respiratory disease (air-sac infection) caused by Mycoplasma gallisepticum and secondary bacterial organisms associated with chronic respiratory disease such as E. coli.

Dosage
1.0 gram of oxytetracycline as oxytetracycline hydrochloride and 1.0 gram carbomycin as carbomycin base per gallon of drinking water.
Limitations

Administer for not more than 5 days. Not for use in chickens producing eggs for human consumption. Withdraw 24 hours before slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Beef heifers fed in confinement for slaughter
Composition / specifications
Type A medicated article containing 100 or 200 milligrams of melengestrol acetate per pound or Type A liquid medicated article containing 500 milligrams of melengestrol acetate per pound. Type A medicated article containing 50 or 100 grams of oxytetracycline per pound.
Cattle (heifers in confinement fed for slaughter)
Indication

For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat) and for the reduction of incidence of liver abscesses in heifers being fed in confinement for slaughter.

Dosage

Feed 0.25 to 2.0 g/ton melengestrol acetate to heifers at a rate of 0.5 to 2.0 lb/hd/day as a top dress or mixed into a complete feed to provide 0.25 to 0.5 mg melengestrol acetate per head per day and 75 to 300 g/ton oxytetracycline to provide 75 mg oxytetracycline per head per day. Melengestrol acetate and oxytetracycline may be fed continuously throughout the time the heifers are being grown and finished for slaughter.

Limitations

Not effective in steers and spayed heifers. Withdrawal periods of three to five days should be avoided to prevent thepossibility that the heifers may come into estrus (heat) at the time of loading.Do not mix with oxytetracycline as a common liquid feed supplement.

Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Beef heifers fed in confinement for slaughter
Composition / specifications
Type A medicated article containing 100 or 200 milligrams of melengestrol acetate per pound or Type A liquid medicated article containing 500 milligrams of melengestrol acetate per pound. Type A medicated article containing 50 or 100 grams of oxytetracycline per pound.
Cattle (heifers fed in confinement for slaughter)
Indication
For increased rate of weight gain, improved feed efficiency, and suppression of estrus (heat, and reduction of liver condemnation due to liver abscesses.
Dosage
Melengestrol acetate, 0.25 to 0.50 milligram per head per day, plus oxytetracycline, 75 milligrams per head per day.
Limitations
Add at the rate of 0.5 to 2.0 pounds per head per day a medicated feed (liquid or dry) containing 0.125 to 1.0 milligram of melengestrol acetate per pound to a feed containing 6 to 10 grams of oxytetracycline per ton; or add at the rate of 0.5 to 2.0 pounds per head per day a dry medicated feed containing 0.125 to 1.0 milligram of melengestrol acetate plus 37.5 to 150 milligrams of oxytetracycline per pound to provide 0.25 to 0.5 milligram of melengestrol acetate and 75 milligrams of oxytetracycline per head per day. Liquid melengestrol acetate may not be mixed with oxytetracycline in a common liquid feed supplement.
Indication

For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat) and for the reduction of incidence of liver abscesses in heifers being fed in confinement for slaughter.

Dosage

Feed 0.25 to 2.0 g/ton melengestrol acetate to heifers at a rate of 0.5 to 2.0 lb/hd/day as a top dress or mixed into a complete feed to provide 0.25 to 0.5 mg melengestrol acetate per head per day and 75 to 300 g/ton oxytetracycline to provide 75 mg oxytetracycline per head per day. Continue feeding throughout the time the heifers are being grown and finished for slaughter.

Limitations

Not effective in steers and spayed heifers. Withdrawal periods of three to five days should be avoided to prevent the possibility that the heifers may come into estrus (heat) at the time of loading. Do not mix with oxytetracycline as a common liquid feed supplement. Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Honey Bees • Fish, Finfish, Fry And Fingerlings • Breeding • No use class stated or implied • Beef • Calves • Dairy, females Under 20 months of age • Growing • Not laying eggs for human consumption • Excluding turkeys producing eggs for human consumption • Sheep, No Use Class Stated Or Implied
Composition / specifications
Each 1.32 grams of TERRAMYCIN-343® powder contains 1 gram of OTC HCl (packets: 2.39, 4.78, and 9.55 oz.; jars: 2.25 lbs.; and pails: 4.5 lbs.).
Chickens
Indication
Control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.
Dosage
200 to 400 milligrams per gallon of drinking water.
Limitations
Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.
Indication

Control of chronic respiratory disease (CRD) and air sac infection caused by Mycoplasma gallisepticum and E. coli susceptible to oxytetracycline; control of fowl cholera caused by Pasteurella multocida susceptible to oxytetracycline.

Dosage
400 to 800 milligrams per gallon of drinking water.
Limitations
Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.
Turkeys
Indication
Control of hexamitiasis caused by Hexamita meleagridis susceptible to oxytetracycline.
Dosage
200 - 400 milligrams per gallon of drinking water.
Limitations
Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.
Indication
Control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.
Dosage
400 milligrams per gallon of drinking water.
Limitations
Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.
Turkeys (Growing)
Indication
Control of complicating bacterial organisms associated with bluecomb (transmissible enteritis, coronaviral enteritis) susceptible to oxytetracycline.
Dosage
25 milligrams per pound of body weight daily
Limitations
Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.
Swine
Indication

Control and treatment of bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis and bacterial pneumonia caused by Pasteurella multocida susceptible to oxytetracycline.

Dosage
10 milligrams per pound of body weight
Limitations

Prepare a fresh solution daily. Administer up to 14 days. Do not use for more than 14 consecutive days. Use as a sole source of oxytetracycline. Zero-day slaughter withdrawal in swine.

Breeding Swine
Indication
Control and treatment of leptospirosis (reducing the incidence of abortions and shedding of leptospira) caused by Leptospira Pomona susceptible to oxytetracycline.
Dosage
10 milligrams per pound of body weight
Limitations

Prepare a fresh solution daily. Administer up to 14 days. Do not use for more than 14 consecutive days. Use as a sole source of oxytetracycline. Zero–day slaughter withdrawal in swine.

Cattle (calves, beef, and non lactating dairy)
Indication

Control and treatment of bacterial enteritis caused by E. coli and bacterial pneumonia (shipping fever complex) caused by P. multocida susceptible to oxytetracycline.

Dosage
10 milligrams per pound of body weight
Limitations
Prepare a fresh solution daily. Administer up to 14 days. Do not use for more than 14 consecutive days. Use as sole source of oxytetracycline. Do not administer this product with milk or milk replacers. Administer 1 hour before or 2 hours after feeding milk or milk replacers. Withdraw 5 days prior to slaughter. A milk discard period has not been established for this product in lactating dairy cattle. Do not use in female dairy cattle 20 months of age or older.
Sheep
Indication

Control and treatment of bacterial enteritis caused by E. coli and bacterial pneumonia (shipping fever complex) caused by P. multocida susceptible to oxytetracycline.

Dosage
10 milligrams per pound of body weight
Limitations

Prepare a fresh solution daily. Administer up to 14 days.Do not use for more than 14 consecutive days. Use as a sole source of oxytetracycline. Withdraw 5 days before slaughter.

Honey Bees
Indication

Control and treatment of American foul brood caused by Paenibacillus larvae.

Dosage
200 milligrams per colony, administered via either a 1:1 sugar syrup (equal parts of sugar and water weight to weight) or dusting with a powdered sugar mixture.
Limitations

The drug is administered in 3 applications of sugar syrup or 3 dustings at 4- to 5- day intervals. The drug should be fed early in the spring or fall and consumed by the bees before main honey flow begins to avoid contamination of production honey. Remove at least 6 weeks prior to main honey flow. Dusting of uncapped brood cells has been reported to cause death of larval honey bees. Do not dust uncapped brood cells.

Finfish
Indication
For skeletal marking of finfish fry and fingerlings.
Dosage
Immerse fish in a solution containing 200 to 700 mg oxytetracycline hydrochloride (buffered) per liter of water for 2 to 6 hours.
Limitations
Solution should be tested on a small number of fish before full-scale use. Do not discharge marking immersion water containing oxytetracycline into surface waters. Oxytetracycline HCl will acidify the water. The pH should be maintained at an acceptable level for fish by the addition of a buffer. Monitor water quality and temperature.

FDA page: Open in Animal Drugs @ FDA

Species: Honey Bees • Breeding • No use class stated or implied • Beef • Calves • Dairy, non-lactating • Not laying eggs for human consumption • Excluding turkeys producing eggs for human consumption • Sheep, No Use Class Stated Or Implied
Composition / specifications
Type A medicated articles contain 10 grams oxytetracycline per pound.
Chickens
Indication

For control of infectious synovitis caused by Mycoplasma synoviae; control of fowl cholera caused by Pasteurella multocida susceptible to oxytetracycline.

Dosage

100 to 200 grams per ton of feed.

Limitations

Feed continuously for 7 to 14 days. At 500 g/ton level,withdraw 24 hours before slaughter. Zero-day withdrawal period for lower use levels. Do not use in low-calcium feed containing less than 0.55% dietary calcium. Use in such feeds may result in violative residues. Do not administer to chickens producing eggs for human consumption.

Indication

For control of chronic respiratory disease (CRD) and air sac infection caused by Mycoplasma gallisepticum and Escherichia coli susceptible to oxytetracycline.

Dosage

400 grams per ton of feed.

Limitations

Feed continuously for 7 to 14 days. At 500 g/ton level, withdraw 24 hours before slaughter. Zero-day withdrawal period for lower use levels. Do not use in low-calcium feed containing less than 0.55% dietary calcium. Use in such feeds may result in violative residues. Do not administer to chickens producing eggs for human consumption.

Indication

For reduction of mortality due to air sacculitis (air-sac-infection) caused by Escherichia coli susceptible to oxytetracycline.

Dosage

500 grams per ton of feed.

Limitations

Feed continuously for 5 days. At 500 g/ton level, withdraw 24 hours before slaughter. Zero-day withdrawal period for lower use levels. Do not use in low-calcium feed containing less than 0.55% dietary calcium. Use in such feeds may result in violative residues. Do not administer to chickens producing eggs for human consumption.

Turkeys
Indication

For control of hexamitiasis caused by Hexamita meleagridis susceptible to oxytetracycline.

Dosage

100 grams per ton of feed.

Limitations

Feed continuously for 7 to 14 days. Do not administer to turkeys producing eggs for human consumption.

Indication

For control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.

Dosage

200 grams per ton of feed.

Limitations

Feed continuously for 7 to 14 days. Withdraw 5 days before slaughter. Do not administer to turkeys producing eggs for human consumption.

Indication

For control of complicating bacterial organisms associated with bluecomb (transmissible enteritis; coronaviral enteritis) susceptible to oxytetracycline.

Dosage

25 milligrams per pound of body weight daily.

Limitations

Feed continuously for 7 to 14 days. Withdraw 5 days before slaughter. Do not administer to turkeys producing eggs for human consumption.

Swine
Indication

For treatment of bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis susceptible to oxytetracycline and treatment of bacterial pneumonia caused by Pasteurella multocida susceptible to oxytetracycline.

Dosage

10 milligrams per pound of body weight daily.

Limitations

Feed continuously for 7 to 14 days.

Swine (breeding)
Indication

For control and treatment of leptospirosis (reducing the incidence of abortion and shedding of leptospirae) caused by Leptospira pomona susceptible to oxytetracycline.

Dosage

10 milligrams per pound of body weight daily.

Limitations

Feed continuously for 14 days.

Cattle (calves, beef, and nonlactating dairy)
Indication

For growing cattle (over 400 lb) for the reduction of the incidence of liver abscesses.

Dosage

75 milligrams per head per day.

Limitations

Feed continuously.

Indication

For prevention and treatment of the early stages of shipping fever complex.

Dosage

0.5 to 2.0 grams per head per day.

Limitations

Feed 3 to 5 days before and after arrival in feedlots.

Indication

For treatment of bacterial enteritis caused by Escherichia coli and bacterial pneumonia (shipping fever complex) caused by Pasteurella multocida susceptible to oxytetracycline.

Dosage

10 milligrams per pound of body weight daily.

Limitations

Feed continuously for 7 to 14 days. Zero-day withdrawal time.

Cattle (calves)
Indication

For treatment of bacterial enteritis caused by Escherichia coli susceptible to oxytetracycline.

Dosage

10 milligrams per pound of body weight daily.

Limitations

Feed continuously for 7 to 14 days in milk replacer or starter feed. Zero-day withdrawal time.

Sheep
Indication

For treatment of bacterial enteritis caused by Escherichia coli and bacterial pneumonia caused by Pasteurella multocida susceptible to oxytetracycline.

Dosage

10 milligrams per pound of body weight daily.

Limitations

Feed continuously for 7 to 14 days. Withdrawal 5 days before slaughter.

Honey bees
Indication

For control of American Foulbrood caused by Paenibacillus larvae, and European Foulbrood caused by Streptococcus pluton susceptible to oxytetracycline.

Dosage

200 milligrams per colony.

Limitations

Remove at least 6 weeks prior to main honey flow.

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied • Beef And Dairy • Calves including preruminating (veal) calves
Composition / specifications
200 mg/mL of oxytetracycline base as oxytetracycline dihydrate
Cattle (beef, dairy, and calves including preruminating (veal) calves)
Indication

For the treatment of the following conditions : 1) bacterial pneumonia caused by Pasteurella spp. (shipping fever) in calves and yearlings, where retreatment is impractical due to husbandry conditions, such as cattle on range, or where repeated restraint is inadvisable; 2) infectious bovine keratoconjunctivitis (pinkeye) cause by Moraxella bovis.

Dosage

A single dosage of 9 milligrams per pound of body weight administered by subcutaneous injection.

Limitations
Indication

For the treatment of pneumonia and shipping fever complex associated with Pasteurella spp. and Haemophilus spp.; infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis; foot rot and diphtheria caused by Fusobacterium necrophorum; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresii; leptospirosis caused by Leptospira pomona; and wound infections and acute metritis caused by strains of staphylococci and streptococci organisms sensitive to oxytetracycline.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day, administered by subcutaneous or intravenous injection. In the treatment of severe foot rot and advanced cases of other indicated diseases, a dosage level of 5 milligrams per pound of body weight per day is recommended. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days. Consult your veterinarian if improvement is not noted within 24 to 48 hours of the beginning of treatment.

Limitations
Swine
Indication

For the treatment of bacterial pneumonia caused by Pasteurella multocida, where retreatment is impractical due to husbandry conditions or where repeated restraint is inadvisable.

Dosage

A single dosage of 9 milligrams of per pound of body weight administered intramuscularly.

Limitations
Indication

For the treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli; pneumonia caused by Pasteurella multocida; and leptospirosis caused by Leptospira pomona.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day administered by intramuscular injection.
Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days. Consult your veterinarian if improvement is not noted within 24 to 48 hours of the beginning of treatment.

Limitations
Sows
Indication

As an aid in the control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.

Dosage

3 mg of oxytetracycline per lb of body weight administered once by intramuscular injection approximately 8 hours before farrowing or immediately after completion of farrowing.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied • Horse, No Use Class Stated Or Implied • No Use Class Stated Or Implied • Cat, No Use Class Stated Or Implied • Sheep, No Use Class Stated Or Implied
Composition / specifications
Each gram of
ointment contains oxytetracycline HCl equivalent to 5 mg of
oxytetracycline and 10,000 units of polymyxin B as the sulfate.
Cattle
Indication

Terramycin® is indicated for the prophylaxis and local treatment of superficial ocular infections due to oxytetracycline and polymyxin-sensitive organisms, including infections due to streptococci, rickettsiae, E. coli, and A.aerogenes, such as conjunctivitis, keratitis, pink eye, corneal ulcer, blepharitis in dogs, cats, cattle, sheep, and horses; ocular infections due to secondary bacterial complications of distemper in dogs, and bacterial inflammatory conditions whichmay occur secondary to other infectious diseases in the above species.

Dosage
Administered topically to the eye 2-4 times daily.
Limitations
Sheep
Indication
Terramycin Ophthalmic Ointment with Polymyxin B Sulfate is indicated for the prophylaxis and local treatment of superficial ocular infections due to oxytetracycline and polymyxin-sensitive organisms, including infections due to streptococci, rickettsiae, E. coli, and A. aerogenes, such as conjunctivitis, keratitis, pink eye, corneal ulcer, blepharitis in dogs, cats, cattle, sheep, and horses; ocular infections due to secondary bacterial complications of distemper in dogs, and bacterial inflammatory conditions which may occur secondary to other infectious diseases in the above species.
Dosage
Administered topically to the eye 2-4 times daily.
Limitations
Horses
Indication
Terramycin Ophthalmic Ointment with Polymyxin B Sulfate is indicated for the prophylaxis and local treatment of superficial ocular infections due to oxytetracycline and polymyxin-sensitive organisms, including infections due to streptococci, rickettsiae, E. coli, and A. aerogenes, such as conjunctivitis, keratitis, pink eye, corneal ulcer, blepharitis in dogs, cats, cattle, sheep, and horses; ocular infections due to secondary bacterial complications of distemper in dogs, and bacterial inflammatory conditions which may occur secondary to other infectious diseases in the above species.
Dosage
Administered topically to the eye 2-4 times daily.
Limitations
Dogs
Indication
Terramycin Ophthalmic Ointment with Polymyxin B Sulfate is indicated for the prophylaxis and local treatment of superficial ocular infections due to oxytetracycline and polymyxin-sensitive organisms, including infections due to streptococci, rickettsiae, E. coli, and A. aerogenes, such as conjunctivitis, keratitis, pink eye, corneal ulcer, blepharitis in dogs, cats, cattle, sheep, and horses; ocular infections due to secondary bacterial complications of distemper in dogs, and bacterial inflammatory conditions which may occur secondary to other infectious diseases in the above species.
Dosage
Administered topically to the eye 2-4 times daily.
Limitations
Cats
Indication
Terramycin Ophthalmic Ointment with Polymyxin B Sulfate is indicated for the prophylaxis and local treatment of superficial ocular infections due to oxytetracycline and polymyxin-sensitive organisms, including infections due to streptococci, rickettsiae, E. coli, and A. aerogenes, such as conjunctivitis, keratitis, pink eye, corneal ulcer, blepharitis in dogs, cats, cattle, sheep, and horses; ocular infections due to secondary bacterial complications of distemper in dogs, and bacterial inflammatory conditions which may occur secondary to other infectious diseases in the above species.
Dosage
Administered topically to the eye 2-4 times daily.
Limitations

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied • Sows • Beef • Dairy, non-lactating
Composition / specifications
200 milligrams oxytetracycline per mL
Sows
Indication

As an aid in the control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli

Dosage

3 mg of oxytetracycline per lb of body weight administered once by intramuscular injection approximately 8 hours before farrowing or immediately after completion of farrowing.

Limitations
Cattle (beef and nonlactating dairy)
Indication

For the treatment of the following conditions : 1) bacterial pneumonia caused by Pasteurella spp. (shipping fever) in yearlings, where re-treatment is impractical due to husbandry conditions, such as cattle on range, or where repeated restraint is inadvisable; 2) infectious bovine keratoconjunctivitis (pinkeye) cause by Moraxella bovis.

Dosage

A single dosage of 9 milligrams per pound of body weight administered intramuscularly. 

Limitations
Indication

For the treatment of pneumonia and shipping fever complex associated with Pasteurella spp. and Hemophilus spp.; infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis; foot rot and diphtheria caused by Fusobacterium necrophorum; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresii; leptospirosis caused by Leptospira pomona; and wound infections and acute metritis caused by strains of staphylococci and streptococci organisms sensitive to oxytetracycline.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day, administered by intravenous or intramuscular injection. In the treatment of severe foot rot and advanced cases of other indicated diseases, a dosage level of 5 milligrams per pound of body weight per day is recommended. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days. Consult your veterinarian if improvement is not noted within 24 to 48 hours of the beginning of treatment.

Limitations
Swine
Indication

For the treatment of bacterial pneumonia caused by Pasteurella multocida, where re-treatment is impractical due to husbandry conditions or where repeated restraint is inadvisable.

Dosage

A single dosage of 9 milligrams of per pound of body weight administered intramuscularly.

Limitations
Indication

For the treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli; pneumonia caused by Pasteurella multocida; and leptospirosis caused by Leptospira pomona.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day administered by intramuscular injection. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days. Consult your veterinarian if improvement is not noted within 24 to 48 hours of the beginning of treatment.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Beef • Dairy, non-lactating
Composition / specifications
Each bolus contains 500 or 1000 milligrams of oxytetracycline hydrochloride.
Beef and Dairy Calves
Indication
For control of bacterial enteritis caused by Salmonella typhimurium and Escherichia coli (colibacillosis) and bacterial pneumonia (shipping fever complex, pasteurellosis) caused by Pasteurella multocida.
Dosage
250 milligrams per 100 pounds of body weight every 12 hours (5 milligrams per pound of body weight daily in two doses) for up to four consecutive days.
Limitations
Dosage should continue until the animal returns to normal and for 24 hours to 48 hours after symptoms have subsided. Treatment should not exceed 4 consecutive days. Do not exceed 500 milligrams per 100 pounds of body weight every 12 hours (10 milligrams per pound daily). Discontinue treatment 7 days prior to slaughter. Not for use in lactating dairy cattle. A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal.
Indication
For treatment of bacterial enteritis caused by Salmonella typhimurium and Escherichia coli (colibacillosis) and bacterial pneumonia (shipping fever complex, pasteurellosis) caused by Pasteurella multocida.
Dosage
500 milligrams per 100 pound of body weight every 12 hours (10 milligrams per pound of body weight daily in two doses).
Limitations
Dosage should continue until the animal returns to normal and for 24 hours to 48 hours after symptoms have subsided. Treatment should not exceed 4 consecutive days. Do not exceed 500 milligrams per 100 pounds of body weight every 12 hours (10 milligrams per pound daily). Discontinue treatment 7 days prior to slaughter. Not for use in lactating dairy cattle. A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal.

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied • Sows • Beef And Dairy • Calves including preruminating (veal) calves
Composition / specifications
200 mg oxytetracycline per mL
Beef cattle, dairy cattle, and calves including prerumenative (veal) calves
Indication

For the treatment of the following conditions: 1) bacterial pneumonia caused by Pasteurella spp. (shipping fever) in calves and yearlings, where retreatment is impractical due to husbandry conditions, such as cattle on range, or where repeated restraint is inadvisable; 2) infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis.

Dosage

A single dosage of 9 milligrams oxytetracycline per pound of body weight administered subcutaneously.


Limitations
Indication

For the treatment of pneumonia and shipping fever complex associated with Pasteurella spp. and Haemophilus spp.; infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis; foot rot and diphtheria caused by Fusobacterium necrophorum; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresii; leptospirosis caused by Leptospira pomona; and wound infections and acute metritis caused by strains of staphylococci and streptococci organisms sensitive to oxytetracycline.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day, administered by subcutaneous or intravenous injection. In the treatment of severe foot rot and advanced cases of other indicated diseases, a dosage of 5 milligrams per pound of body weight per day is recommended. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days. Consult your veterinarian if improvement is not noted within 24 to 48 hours of the beginning of treatment.

Limitations
Swine
Indication

For the treatment of bacterial pneumonia caused by Pasteurella multocida, where retreatment is impractical due to husbandry conditions or where repeated restraint is inadvisable.

Dosage

A single dosage of 9 milligrams oxytetracycline per pound of body weight administered intramuscularly.


Limitations
Indication

For the treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli; pneumonia caused by Pasteurella multocida; and leptospirosis caused by Leptospira pomona.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day administered by intramuscular injection. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days. Consult your veterinarian if improvement is not noted within 24 to 48 hours of the beginning of treatment.

Limitations
Swine (sows)
Indication

As an aid in the control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.

Dosage

3 mg of oxytetracycline per lb of body weight administered once by intramuscular injection approximately 8 hours before farrowing or immediately after completion of farrowing.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied • Sows • Calves, Including Prerumenative Veal • Beef • Dairy
Composition / specifications
200 mg oxytetracycline base as oxytetracycline dihydrate per mL
Beef cattle, dairy cattle, and calves including prerumenative (veal) calves
Indication

Treatment of infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis; and in the treatment of the following conditions where retreatment is impractical due to husbandry conditions, such as cattle on range, or where their repeated restraint is inadvisable: bacterial pneumonia caused by Pasteurella spp. (shipping fever) in calves and yearlings, and anaplasmosis caused by Anaplasma marginale.

Dosage

A single dosage of 9 milligrams oxytetracycline per pound of body weight administered intramuscularly or subcutaneously.

Limitations
Indication

For the treatment of pneumonia and shipping fever complex associated with Pasteurella spp. and Hemophilus spp.; infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis; foot rot and diphtheria caused by Fusobacterium necrophorum; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresii; leptospirosis caused by Leptospira pomona; anaplasmosis caused by Anaplasma marginale; anthrax caused by Bacillus anthracis; and wound infections and acute metritis caused by strains of staphylococci and streptococci organisms sensitive to oxytetracycline.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day, administered by intravenous, subcutaneous, or intramuscular injection. In the treatment of severe foot-rot and advanced cases of other indicated diseases, a dosage of 5 milligrams per pound of body weight per day is recommended. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days. Consult your veterinarian if improvement is not noted within 24 to 48 hours of the beginning of treatment.

Limitations
Swine
Indication

For the treatment of bacterial pneumonia caused by Pasteurella multocida, where retreatment is impractical due to husbandry conditions or where repeated restraint is inadvisable.

Dosage

A single dosage of 9 milligrams of oxytetracycline per pound of body weight administered intramuscularly.

Limitations
Indication

For the treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli; pneumonia caused by Pasteurella multocida; and leptospirosis caused by Leptospira pomona.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day administered by intramuscular injection. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days. Consult your veterinarian if improvement is not noted within 24 to 48 hours of the beginning of treatment.

Limitations
Swine (sows)
Indication

As an aid in the control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.

Dosage

3 mg of oxytetracycline per lb of body weight administered once by intramuscular injection approximately 8 hours before farrowing or immediately after completion of farrowing.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied • Sows • Beef • Dairy
Composition / specifications
200 mg oxytetracycline per mL
Beef cattle; dairy cattle; and calves, including preruminating (veal) calves
Indication

For the treatment of the following conditions: 1) bacterial pneumonia caused by Pasteurella spp. (shipping fever) in calves and yearlings, where retreatment is impractical due to husbandry conditions, such as cattle on range, or where repeated restraint is inadvisable; 2) infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis.

Dosage

A single dosage of 9 milligrams oxytetracycline per pound of body weight administered intramuscularly or subcutaneously.

Limitations
Indication

For the treatment of pneumonia and shipping fever complex associated with Pasteurella spp. and Haemophilus spp; infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis; foot rot and diphtheria caused by Fusobacterium necrophorum; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresii; leptospirosis caused by Leptospira pomona; and wound infections and acute metritis caused by strains of staphylococci and streptococci organisms sensitive to oxytetracycline.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day, administered by intravenous, subcutaneous, or intramuscular injection. In the treatment of severe foot-rot and advanced cases of other indicated diseases, a dosage of 5 milligrams per pound of body weight per day is recommended. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days. Consult your veterinarian if improvement is not noted within 24 to 48 hours of the beginning of treatment.

Limitations
Swine
Indication

 For the treatment of bacterial pneumonia caused by Pasteurella multocida, where re-treatment is impractical due to husbandry conditions or where repeated restraint is inadvisable.

Dosage

A single dosage of 9 milligrams of oxytetracycline per pound of body weight administered intramuscularly.

Limitations
Indication

For the treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli; pneumonia caused by Pasteurella multocida; and leptospirosis caused by Leptospira pomona.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day administered by intramuscular injection. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days. Consult your veterinarian if improvement is not noted within 24 to 48 hours of the beginning of treatment.

Limitations
Swine (sows)
Indication

As an aid in the control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.

Dosage

3 mg of oxytetracycline per lb of body weight administered once by intramuscular injection approximately 8 hours before farrowing or immediately after completion of farrowing.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied • Sows with litters or about to farrow • Calves, Including Prerumenative Veal • Beef • Dairy
Composition / specifications
200 milligrams oxytetracycline per mL.
Cattle (beef cattle; dairy cattle; calves, including preruminating (veal) calves)
Indication

For the treatment of the following conditions: 1) bacterial pneumonia caused by Pasteurella spp. (shipping fever) in calves and yearlings, where retreatment is impractical due to husbandry conditions, such as cattle on range, or where repeated restraint is inadvisable; 2) infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis.

Dosage

A single dosage of 9 milligrams oxytetracycline per pound of body weight administered intramuscularly or subcutaneously.

Limitations
Indication

For the treatment of pneumonia and shipping fever complex associated with Pasteurella spp. and Hemophilus spp; infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis; foot-rot and diphtheria caused by Fusobacterium necrophorum; bacterial bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresii; leptospirosis caused by Leptospira pomona; and wound infections and acute metritis caused by strains of staphylococci and streptococci organisms sensitive to oxytetracycline.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day, administered by intravenous, subcutaneous, or intramuscular injection. In the treatment of severe foot-rot and advanced cases of other indicated diseases, a dosage of 5 milligrams per pound of body weight per day is recommended. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days. Consult your veterinarian if improvement is not noted within 24 to 48 hours of the beginning of treatment.

Limitations
Swine
Indication

Where re-treatment for pneumonia is impractical. For the treatment of bacterial pneumonia caused by Pasteurella multocida, where re-treatment is impractical due to husbandry conditions or where repeated restraint is inadvisable.

Dosage

A single dosage of 9 milligrams oxytetracycline per pound of body weight administered intramuscularly.

Limitations
Indication

For the treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli; pneumonia caused by Pasteurella multocida; and leptospirosis caused by Leptospira pomona.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day administered by intramuscular injection. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days. Consult your veterinarian if improvement is not noted within 24 to 48 hours of the beginning of treatment.

Limitations
Sows
Indication

As an aid in the control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.

Dosage

3 mg of oxytetracycline per lb of body weight administered once by intramuscular injection approximately 8 hours before farrowing or immediately after completion of farrowing.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied • Sows with litters or about to farrow • Beef • Dairy • Calves including preruminating (veal) calves
Composition / specifications
Each mL contains 200 mg of oxytetracycline base as amphoteric oxytetracycline
Cattle (beef cattle; dairy cattle; calves, including preruminating (veal) calves)
Indication

For the treatment of the following conditions: 1) bacterial pneumonia caused by Pasteurella spp. (shipping fever) in calves and yearlings, where retreatment is impractical due to husbandry conditions, such as cattle on range, or where repeated restraint is inadvisable; 2) infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis.

Dosage

A single dosage of 9 milligrams oxytetracycline per pound of body weight administered subcutaneously.

Limitations
Indication

For the treatment of pneumonia and shipping fever complex associated with Pasteurella spp. and Hemophilus spp.; infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis; foot rot and diphtheria caused by Fusobacterium necrophorum; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresii; leptospirosis caused by Leptospira pomona; and wound infections and acute metritis caused by strains of staphylococci and streptococci organisms sensitive to oxytetracycline.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day, administered by subcutaneous or intravenous injection. In the treatment of severe foot rot and advanced cases of other indicated diseases, a dosage of 5 milligrams per pound of body weight per day is recommended. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days. Consult your veterinarian if improvement is not noted within 24 to 48 hours of the beginning of treatment.

Limitations
Swine
Indication

For the treatment of bacterial pneumonia caused by Pasteurella multocida, where retreatment is impractical due to husbandry conditions or where repeated restraint is inadvisable.

Dosage

A single dosage of 9 milligrams oxytetracycline per pound of body weight administered intramuscularly.

Limitations
Indication

For the treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli; pneumonia caused by Pasteurella multocida; and leptospirosis caused by Leptospira pomona.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day administered by intramuscular injection. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days. Consult your veterinarian if improvement is not noted within 24 to 48 hours of the beginning of treatment.

Limitations
Sows
Indication

As an aid in the control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.

Dosage

3 mg of oxytetracycline per lb of body weight administered once by intramuscular injection approximately 8 hours before farrowing or immediately after completion of farrowing.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Beef • Dairy, non-lactating • Beef and dairy calves, excluding veal calves
Composition / specifications
Each milliliter of sterile solution contains 100 milligrams of oxytetracycline hydrochloride.
Cattle (beef, non-lactating dairy, and beef and dairy calves [excluding veal])
Indication

Treatment of bacterial pneumonia and shipping fever complex associated with Pasteurella spp.; bacterial enteritis (scours) caused by Escherichia coli; necrotic pododermatitis (foot rot) and calf diphtheria caused by Fusobacterium necrophorum; wooden tongue caused by Actinobacillus lignieresi; and wound infections, acute metritis, and traumatic injury caused by oxytetracycline susceptible staphylococcal and streptococcal organisms.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day (3 to 5 mL per 100 pounds of body weight) by intravenous injection. Severe foot rot and the severe forms of the indicated diseases should be treated with 5 mg per pound of body weight. Treatment should be continued 24 to 48 hours following remission of disease symptoms, not to exceed a total of 4 consecutive days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied • Sows with litters or about to farrow • Beef • Dairy
Composition / specifications
200 milligrams oxytetracycline per milliliter.
Sows
Indication

As an aid in the control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.

Dosage

3 mg of oxytetracycline per lb of body weight administered once by intramuscular injection approximately 8 hours before farrowing or immediately after completion of farrowing.

Limitations
Cattle (beef and dairy)
Indication

For the treatment of the following conditions : 1) bacterial pneumonia caused by Pasteurella spp. (shipping fever) in yearlings, where re-treatment is impractical due to husbandry conditions, such as cattle on range, or where repeated restraint is inadvisable; 2) infectious bovine keratoconjunctivitis (pinkeye) cause by Moraxella bovis.

Dosage

A single dosage of 9 milligrams per pound of body weight administered intramuscularly or subcutaneously.
Intramuscular administration is not recommended according to Beef Quality Assurance Guidelines.

Limitations
Indication

For the treatment of pneumonia and shipping fever complex associated with Pasteurella spp. and Haemophilus spp.; infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis; foot-rot and diphtheria caused by Fusobacterium necrophorum; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresii; leptospirosis caused by Leptospira pomona; and wound infections and acute metritis caused by strains of staphylococci and streptococci organisms sensitive to oxytetracycline.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day, administered by intravenous, subcutaneous, or intramuscular injection. In the treatment of severe foot rot and advanced cases of other indicated diseases, a dosage level of 5 milligrams per pound of body weight per day is recommended. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days. Consult your veterinarian if improvement is not noted within 24 to 48 hours of the beginning of treatment. Intramuscular administration is not recommended according to Beef Quality Assurance Guidelines.

Limitations
Swine
Indication

For the treatment of bacterial pneumonia caused by Pasteurella multocida, where re-treatment is impractical due to husbandry conditions or where repeated restraint is inadvisable.

Dosage

A single dosage of 9 milligrams of per pound of body weight administered intramuscularly.

Limitations
Indication

For the treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli; pneumonia caused by Pasteurella multocida; and leptospirosis caused by Leptospira pomona.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day administered by intramuscular injection. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days. Consult your veterinarian if improvement is not noted within 24 to 48 hours of the beginning of treatment.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Beef And Non-Lactating Dairy • Beef and dairy calves, excluding veal calves
Composition / specifications
Each milliliter of sterile solution contains 100 milligrams of oxytetracycline hydrochloride.
Cattle (beef, nonlactating dairy, and beef and dairy calves [excluding veal])
Indication

Treatment of bacterial pneumonia and shipping fever complex associated with Pasteurella spp.; bacterial enteritis (scours) caused by Escherichia coli; necrotic pododermatitis (foot rot) and calf diphtheria caused by Fusobacterium necrophorum; wooden tongue caused by Actinobacillus lignieresi; and wound infections, metritis, and traumatic injury caused by oxytetracycline susceptible staphylococcal and streptococcal organisms.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day (3 to 5 mL per 100 pounds of body weight)
by intravenous injection. Severe foot rot and the severe forms of the indicated diseases should be treated with 5 mg per pound of body weight. Treatment should be continued 24 to 48 hours following remission of disease symptoms, not to exceed a total of 4 consecutive days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied • Sows with litters or about to farrow • Beef • Calves • Dairy, non-lactating
Composition / specifications
Each milliliter of sterile solution contains 100 milligrams of oxytetracycline (as oxytetracycline hydrochloride).
Swine
Indication

For treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli, pneumonia caused by Pasteurella multocida, and leptospirosis caused by Leptospira pomona.

Dosage
Three to 5 milligrams of oxytetracycline per pound of body weight per day. Administer intramuscularly.
Limitations
Do not inject more than 5 milliliters per site. Do not use for more than 4 consecutive days. Discontinue treatment at least 26 days before slaughter.
Swine (sows)
Indication

As an aid in control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.

Dosage
3 milligrams of oxytetracycline per pound of body weight, approximately 8 hours before farrowing or immediately after completion of farrowing. Administer intramuscularly.
Limitations
Do not inject more than 5 milliliters per site. Do not use for more than 4 consecutive days. Discontinue treatment at least 26 days before slaughter.
Cattle (beef and nonlactating dairy)
Indication

Treatment of diseases due to oxytetracycline-susceptible organisms as follows: Pneumonia and shipping fever complex associated with Pasteurella species, Hemophilus species, and Klebsiella species, foot-rot and diphtheria caused by Spherophorus necrophorus, bacterial enteritis (scours) caused by Escherichia coli, wooden tongue caused by Actinobacillus lignieresi, leptospirosis caused by Leptospira pomona, and wound infections and acute metritis caused by Staphylococcus species and Streptococcus species. If labeled for use by or on the order of a licensed veterinarian, it may be used for the treatment of anaplasmosis caused by Anaplasma marginale.

Dosage
Three to 5 milligrams of oxytetracycline per pound of body weight per day; 5 milligrams per pound of body weight per day for the treatment of anaplasmosis, severe foot-rot, and severe cases of other indicated diseases. For 100-milligram-per-milliliter solution, administer intramuscularly.
Limitations
Treatment of all diseases should be instituted early and continue for 24 to 48 hours beyond remission of disease symptoms, but not to exceed a total of 4 consecutive days. Consult your veterinarian if no improvement is noted within 48 hours. Do not inject more than 10 milliliters per site in adult cattle, reducing the volume according to age and body size to 0.5 to 2 milliliters in small calves. Exceeding the highest recommended dose of 5 milligrams per pound of body weight, administering at recommended levels for more than 4 consecutive days, and/or exceeding 10 milliliters intramuscularly per injection site may result in antibiotic residues beyond the withdrawal time. Discontinue treatment at least 18 days prior to slaughter. Not for use in lactating dairy cattle. This drug product is not approved for use in female dairy cattle 20 months of age or older, including dry dairy cows. Use in these cattle may cause drug residues in milk and /or in calves born to these cows.

FDA page: Open in Animal Drugs @ FDA

Species: Beef And Non-Lactating Dairy • Beef and dairy calves, excluding veal calves
Composition / specifications
Each milliliter of sterile solution contains 100 milligrams of oxytetracycline hydrochloride.
Cattle (beef, nonlactating dairy, and beef and dairy calves [excluding veal])
Indication

Treatment of bacterial pneumonia and shipping fever complex associated with Pasteurella spp.; bacterial enteritis (scours) caused by Escherichia coli; necrotic pododermatitis (foot rot) and calf diphtheria caused by Fusobacterium necrophorum; wooden tongue caused by Actinobacillus lignieresi; and wound infections, acute metritis, and traumatic injury caused by oxytetracycline-susceptible staphylococcal and streptococcal organisms.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day (3 to 5 mL per 100 pounds of body weight) by intravenous injection. Severe foot rot and the severe forms of the indicated diseases should be treated with 5 mg per pound of body weight. Treatment should be continued 24 to 48 hours following remission of disease symptoms, not to exceed a total of 4 consecutive days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Beef And Non-Lactating Dairy • Beef calves • Dairy calves
Composition / specifications
The drug contains 50 milligrams of oxytetracycline hydrochloride in each milliliter of sterile solution.
Cattle (beef and non-lactating dairy, beef and dairy calves)
Indication

Treatment of pneumonia and shipping fever complex associated with Pasteurella sp., Hemophilus sp., and Klebsiella sp., bacterial enteritis (scours) caused by Escherichia coli, foot rot and diphtheria caused by Spherophorus necrophorus, wooden tongue caused by Actinobacillus lignieresi, leptospirosis caused by Leptospira pomona, and wound infections, acute metritis, and traumatic injury caused by a variety of bacterial organisms (such as streptococcal and staphylococcal organisms.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day (6 to 10 mL per 100 pounds of body weight) by intramuscular injection. For leptospirosis, severe foot rot and severe forms of the indicated diseases, 5 milligrams per pound of body weight per day. Treatment should be continued 24 to 48 hours following remission of disease symptoms, not to exceed a total of 4 consecutive days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied • Sows with litters or about to farrow • Beef • Calves, excluding veal calves • Dairy, non-lactating
Composition / specifications
Each milliliter of sterile solution contains 100 milligrams of oxytetracycline as oxytetracycline hydrochloride.
Cattle (beef and nonlactating dairy, beef and dairy calves [excluding veal calves])
Indication

Treatment of pneumonia and shipping fever complex associated with Pasteurella spp., Haemophilus spp., and Klebsiella spp.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day (3 to 5 mL per 100 pounds of body weight) by intramuscular, subcutaneous, or intravenous injection. Treatment should be continued 24 to 48 hours following
remission of disease symptoms, not to exceed a total of 4 consecutive days.

Limitations
Swine
Indication

For treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli, pneumonia caused by Pasteurella multocida, and leptospirosis caused by Leptospira pomona.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day by intramuscular or intravenous injection.

Limitations
Swine (Sows)
Indication

As an aid in control of porcine colibacillosis (baby pig scours) in suckling pigs caused by Escherichia coli.

Dosage

3 milligrams of oxytetracycline per pound of body weight by intramuscular injection, approximately 8 hours before farrowing or immediately after completion of farrowing.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied • Sows • Beef And Non-Lactating Dairy
Composition / specifications
Each milliliter of sterile solution contains 50 milligrams of oxytetracycline (as oxytetracycline hydrochloride).
Cattle (beef and nonlactating dairy)
Indication

Treatment of pneumonia and shipping fever complex associated with Pasteurella sp., Hemophilus sp., and Klebsiella sp., foot rot and diphtheria caused by Spherophorus necrophorus, bacterial enteritis (scours) caused by Escherichia coli, wooden tongue caused by Actinobacillus lignieresi, leptospirosis caused by Leptospira pomona, acute metritis, anaplasmosis caused by Anaplasma marginale, and wound infections caused by Staphylococcal and Streptococcal organisms.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day (6 to 10 mL per 100 pounds of body weight) by intramuscular or intravenous injection. In severe forms of foot rot, anaplasmosis, and other severe disease forms, 5 milligrams per pound of body weight per
day (10 mL per 100 pounds of body weight). Treatment should be continued 24 to 48 hours following remission of
disease symptoms, not to exceed a total of 4 days.

Limitations
Swine
Indication

For treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli, pneumonia caused by Pasteurella multocida, and leptospirosis caused by Leptospira pomona.

Dosage

3 to 5 milligrams of oxytetracycline per pound of body weight per day (6 to 10 mL per 100 pounds of body weight) by intramuscular injection.

Limitations
Swine (Sows)
Indication

As an aid in control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.

Dosage

3 milligrams of oxytetracycline per pound of body weight (6 mL per 100 lbs. body weight), by intramuscular injection, approximately 8 hours before farrowing or immediately after completion of farrowing.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Pacific Salmon, Reared • Freshwater-Reared Salmonids • Catfish, Reared • Freshwater-reared salmonids weighing up to 55 grams • Lobster
Composition / specifications
Type A medicated articles: 100 grams per pound. The amount of mono-alkyl (C8-C18) trimethylammonium oxytetracycline expressed is expressed in terms of an equivalent amount of oxytetracycline hydrochloride or the amount of oxytetracycline dihydrate base is expressed in terms of an equivalent amount of oxytetracycline hydrochloride.
Pacific Salmon
Indication
For marking of skeletal tissue.
Dosage

250 milligrams of Oxytetracycline per kilogram of fish per day (11.35 grams per 100 pounds of fish per day) in fish feed.

Limitations

For salmon not over 30 grams body weight. Administer as sole ration for 4 consecutive days. 

Freshwater-reared salmonids
Indication

Control of ulcer disease caused by Haemophilus piscium, furunculosis caused by Aeromonas salmonicida, bacterial hemorrhagic septicemia caused by Aeromonas hydrophila, and pseudomonas disease.

Dosage
2.5 to 3.75 grams Oxytetracycline per 100 pounds of fish per day in fish feed.
Limitations

Administer in mixed ration for 10 days. 

Catfish
Indication

Control of bacterial hemorrhagic septicemia caused by Aeromonas hydrophila and pseudomonas disease.

Dosage
2.5 to 3.75 grams Oxytetracycline per 100 pounds of fish per day in fish feed.
Limitations

Administer in mixed ration for 10 days. Do not administer when water temperature is below 16.7 degrees C (62 degrees F).

Freshwater-reared salmonids
Indication
Control of mortality due to coldwater disease associated with Flavobacterium psychrophilum.
Dosage

3.75 g oxytetracycline per 100 lb of fish per day for 10 days.

Limitations

Administer in mixed ration for 10 days. 

Freshwater-reared salmonids
Indication

Control of mortality due to columnaris disease associated with Flavobacterium columnare.

Dosage

3.75 g oxytetracycline per 100 lb of fish per day for 10 days.

Limitations

Administer in mixed ration for 10 days. 

Lobster
Indication
Control of gaffkemia caused by Aerococcus viridans.
Dosage
1 gram Oxytetracycline per pound of medicated feed in fish feed.
Limitations
Administer as sole ration for 5 consecutive days.
Freshwater-reared salmonids weighing up to 55 grams
Indication

For marking the skeletal tissue

Dosage

3.75 g oxytetracycline per 100 lb of fish per day for 10 days. Feed for 10 days.

Limitations
Catfish
Indication

Control of mortality due to columnaris disease associated with Flavobacterium columnare

Dosage

3.75 g oxytetracycline per 100 lb of fish per day for 10 days. Administer in mixed ration for 10 days. Do not administer when water temperature is below 16.7 degrees C (62 degrees F).

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Breeding • No use class stated or implied • Growing • Not laying eggs for human consumption • Excluding turkeys producing eggs for human consumption
Composition / specifications
Each 2.73 grams of powder contains 1 gram of oxytetracycline hydrochloride (packets: 9.87 oz, 3.09 lb and 3.91 lb)
Chickens
Indication

Control of chronic respiratory disease (CRD) and air sac infections caused by Mycoplasma gallisepticum and E. coli susceptible to oxytetracycline; control of fowl cholera caused by Pasteurella multocida susceptible to oxytetracycline.

Dosage

400 to 800 milligrams per gallon of drinking water.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.

Indication

Control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.

Dosage

200 to 400 milligrams per gallon of drinking water.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.

Turkeys
Indication

Control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.

Dosage

400 milligrams per gallon of drinking water.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.

Indication

Control of hexamitiasis caused by Hexamita meleagridis susceptible to oxytetracycline.

Dosage

200 to 400 milligrams per gallon of drinking water.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.

Turkeys (growing)
Indication

Control of complicating bacterial organisms associated with bluecomb (transmissible enteritis, coronaviral enteritis) susceptible to oxytetracycline.

Dosage

25 milligrams per pound of body weight in drinking water.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.

Swine
Indication

Control and treatment of bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis and bacterial pneumonia caused by Pasteurella multocida susceptible to oxytetracycline.

Dosage

10 milligrams per pound of body weight daily in drinking water.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Use as sole source of OTC. Administer up to 5 days. Do not use for more than 5 consecutive days.

Swine (breeding stock)
Indication

Control and treatment of leptospirosis (reducing the incidence of abortions and shedding of leptospira) caused by Leptospira pomona susceptible to oxytetracycline.

Dosage

10 milligrams per pound of body weight daily in drinking water.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Use as sole source of OTC. Administer up to 5 days. Do not use for more than 5 consecutive days.

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied • Sows • Calves, Including Prerumenative Veal • Beef • Dairy, non-lactating
Composition / specifications
Each mL of solution contains 300 mg oxytetracycline base.
Beef Cattle, Non-lactating Dairy Cattle, and Calves including Pre-ruminating (Veal) Calves
Indication

For treatment of bacterial pneumonia caused by Pasteurella species (shipping fever) in calves and yearlings where treatment is impractical due to husbandry conditions, such as cattle on range, or where their repeated restraint is inadvisable; or for treatment of infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis.

Dosage

9 to 13.6 milligrams per pound of body weight. Administer once intramuscularly or subcutaneously.

Limitations
Indication

For control of respiratory disease in cattle at high risk of developing bovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica.

Dosage

13.6 milligrams per pound of body weight. Administer once intramuscularly or subcutaneously.

Limitations
Indication

For treatment of pneumonia and shipping fever complex associated with Pasteurella species and Histophilus species, foot-rot and diphtheria caused by Fusobacterium necrophorum, bacterial enteritis (scours) caused by Escherichia coli, wooden tongue caused by Actinobacillus lignieresii, leptospirosis caused by Leptospira pomona, and wound infections and acute metritis caused by strains of staphylococcal and streptococcal organisms sensitive to oxytetracycline.

Dosage

3 to 5 milligrams per pound of body weight per day. For treatment of severe foot-rot and advanced cases of other indicated diseases, 5 milligrams per pound of body weight per day. Administer intramuscularly, subcutaneously, or intravenously. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days.

Limitations
Swine
Indication

For treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli, pneumonia caused by Pasteurella multocida, and leptospirosis caused by Leptospira pomona.

Dosage

3 to 5 milligrams per pound of body weight per day. Administer intramuscularly. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days.

Limitations
Indication

For treatment of pneumonia caused by Pasteurella multocida where retreatment for pneumonia is impractical.

Dosage

9 milligrams per pound of body weight. Administer once intramuscularly.

Limitations
Swine (Sows)
Indication

As an aid in control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.

Dosage

3 milligrams per pound of body weight. Administer once intramuscularly approximately 8 hours before farrowing or immediately after completion of farrowing.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Beef • Dairy, non-lactating
Composition / specifications
Each mL contains 50 mg of oxytetracycline hydrochloride
Cattle (Beef and Non-Lactating Dairy)
Indication
Treatment of diseases due to oxytetracycline-susceptible organisms as follows: pneumonia and shipping fever complex associated with Pasteurella species and Hemophilus species; foot rot and diphtheria caused by Fusobacterium necrophorum; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresii; leptospirosis caused by Leptospira Pomona; acute metritis and wound infections caused by staphylococcal and streptococcal organisms; if labeled for use by or on the order of a licensed veterinarian, it may be used for treatment of anaplasmosis caused by Anaplasma marginale and anthrax caused by Bacillus anthracis.
Dosage
3 to 5 milligrams per pound of body weight daily, 5 milligrams per pound for anaplasmosis, severe foot rot, and severe forms of other diseases. Administer by intravenous injection.
Limitations

Treatment should be continued 24 to 48 hours following remission of disease symptoms, but not to exceed a total of 4 consecutive days. If no improvement occurs within 24 to 48 hours, reevaluate diagnosis and therapy. Discontinue use at least 19 days prior to slaughter. This drug product is not approved for use in female dairy cattle 20months of age or older, including dry dairy cows. Use in these cattle may cause drug residues in milk and/or in calves born to these cows.

FDA page: Open in Animal Drugs @ FDA

Species: Beef • Calves • Dairy, non-lactating
Composition / specifications
Each milliliter of sterile solution contains 50 milligrams of oxytetracycline hydrochloride.
Cattle (beef, beef calves, nonlactating dairy, dairy calves)
Indication
The drug is used for treatment of bacterial pneumonia and shipping fever complex associated with Pasteurella species; foot-rot and diphtheria caused by Spherophorus necrophorus; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresi; wound infections and acute metritis caused by staphylococcal and streptococcal organisms susceptible to oxytetracycline.
Dosage
Administer 3 to 5 milligrams of the oxytetracycline hydrochloride intramuscularly per pound of body weight per day. In severe forms of the indicated diseases, administer the equivalent of 5 milligrams of oxytetracycline hydrochloride per pound of body weight per day. Continue treatment 24 to 48 hours following remission of disease symptoms, not to exceed a total of 4 consecutive days. Reduce the volume administered per injection site according to age and body size. In calves weighing 100 pounds or less inject only 2 milliliters per site.
Limitations

If no improvement is noted within 24 to 48 hours, consult a veterinarian for diagnosis and therapy. In adult livestock, do not inject more than 10 milliliters at any one site. Rapid intravenous administration may result in animal collapse. Oxytetracycline should be administered intravenously slowly over a period of at least5 minutes.

FDA page: Open in Animal Drugs @ FDA

Species: Beef • Calves • Dairy, non-lactating
Composition / specifications
Each milliliter of sterile solution contains 100 milligrams of oxytetracycline hydrochloride.
Cattle (beef and nonlactating dairy)
Indication
Treatment of diseases due to oxytetracycline-susceptible organisms as follows: Pneumonia and shipping fever complex associated with Pasteurella species and Hemophilus species, foot-rot and diphtheria caused by Fusobacterium necrophorum, bacterial enteritis (scours) caused by Escherichia coli, wooden tongue caused by Actinobacillus lignieresii, leptospirosis caused by Leptospira pomona, and wound infections and acute metritis caused by Staphylococcus species and Streptococcus species. If labeled for use by or on the order of a licensed veterinarian, it may be used for the treatment of anaplasmosis caused by Anaplasma marginale and anthrax caused by Bacillus anthracis.
Dosage
3 to 5 milligrams of oxytetracycline per pound of body weight per day; 5 milligrams per pound of body weight per day for treatment of anaplasmosis, severe foot-rot, and severe cases of other indicated diseases. Administer intramuscularly.
Limitations
Treatment of all diseases should be instituted early and continue for 24 to 48 hours beyond remission of disease symptoms but not to exceed a total of 4 consecutive days. Consult your veterinarian if no improvement is noted within 48 hours. Do not inject more than 10 milliliters per site in adult cattle, reducing the volume according to age and body size to 1 to 2 milliliters in small calves. Exceeding the highest recommended dose of 5 milligrams per pound of body weight, administering at recommended levels for more than 4 consecutive days, and/or exceeding 10 milliliters intramuscularly per injection site may result in antibiotic residues beyond the withdrawal time. Discontinue treatment at least 15 days prior to slaughter. Not for use in lactating dairy cattle.

FDA page: Open in Animal Drugs @ FDA

Species: Beef • Calves • Dairy, non-lactating
Composition / specifications
The drug contains 100 milligrams of oxytetracycline hydrochloride in each milliliter of sterile solution.
Cattle (beef and nonlactating dairy)
Indication
The drug is intended for use in the treatment of disease due to oxytetracycline-susceptible organisms in beef cattle and non-lactating dairy cattle. It is indicated in the treatment of pneumonia and shipping fever complex associated with Pasteurella species, Hemophilus species, Klebsiella species, foot-rot and diphtheria caused by Spherophorus necrophorus, bacterial enteritis (scours) caused by Escherichia coli, wooden tongue caused by Actinobacillus lignieresi, acute metritis, and wound infections caused by staphylococcal and streptococcal organisms.
Dosage
It is administered to cattle at a dosage level of 3 to 5 milligrams per pound of body weight per day. It is administered intravenously from a 100 milligram per milliliter solution. Severe foot-rot and the severe forms of the indicated diseases should be treated with 5 milligrams per pound of body weight. Treatment should be continued 24 to 48 hours following remission of disease symptoms, however, not to exceed a total of 4 consecutive days. If no improvement is noted within 24 hours consult a veterinarian. When injecting the drug intramuscularly do not inject more than 10 milliliters per site in adult cattle. Reduce the amount injected at each site according to the size of the animal. For very small calves do not use more than 2 milliliters per injection site.
Limitations
Not for use in lactating dairy cattle. Discontinue treatment at least 19 days prior to slaughter. When administered intramuscularly within 30 days of slaughter, muscle discoloration may necessitate trimming of the injection site and surrounding tissues.

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied • Sows with litters or about to farrow • Beef • Calves • Dairy, non-lactating
Composition / specifications
Each milliliter of sterile solution contains 100 milligrams of oxytetracycline hydrochloride.
Swine
Indication
For treatment of bacterial enteritis (scours colibacillosis) caused by Escherichia coli, pneumonia caused by Pasteurella multocida, and leptospirosis caused by Leptospira pomona.
Dosage
3 to 5 milligrams of oxytetracycline per pound of body weight per day. Administer intramuscularly.
Limitations
Do not inject more than 5 milliliters per site in adult swine, reducing the volume according to age and body size to 1 to 2 milliliters in young pigs. Discontinue treatment at least 22 days prior to slaughter.
Swine (sows with litters or about to farrow)
Indication
As an aid in control of infections enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.
Dosage
3 milligrams of oxytetracycline per pound of body weight, administered once, approximately 8 hours before farrowing or immediately after completion of farrowing. Administer intramuscularly.
Limitations
Do not inject more than 5 milliliters per site in adult swine, reducing the volume according to age and body size to 1 to 2 milliliters in young pigs. Discontinue treatment at least 22 days prior to slaughter.
Cattle (beef and nonlactating dairy)
Indication
Treatment of diseases due to oxytetracycline-susceptible organisms as follows: Pneumonia and shipping fever complex associated with Pasteurella species and Hemophilus species, foot-rot and diphtheria caused by Fusobacterium necrophorum, bacterial enteritis (scours) caused by Escherichia coli, wooden tongue caused by Actinobacillus lignieresii, leptospirosis caused by Leptospira pomona, and wound infections and acute metritis caused by Staphylococcus species and Streptococcus species If labeled for use by or on the order of a licensed veterinarian, it may be used for the treatment of anaplasmosis caused by Anaplasma marginale and anthrax caused by Bacillus anthracis.
Dosage
3 to 5 milligrams of oxytetracycline per pound of body weight per day; 5 milligrams per pound of body weight per day for treatment of anaplasmosis, severe foot-rot, and severe cases of other indicated diseases. Administer intramuscularly.
Limitations
Treatment of all diseases should be instituted early and continue for 24 to 48 hours beyond remission of disease symptoms but not to exceed a total of 4 consecutive days. Consult your veterinarian if no improvement is noted within 48 hours. Do not inject more than 10 milliliters per site in adult cattle, reducing the volume according to age and body size to 1 to 2 milliliters in small calves. Exceeding the highest recommended dose of 5 milligrams per pound of body weight, administering at recommended levels for more than 4 consecutive days, and/or exceeding 10 milliliters intramuscularly per injection site may result in antibiotic residues beyond the withdrawal time. Discontinue treatment at least 15 days prior to slaughter. Not for use in lactating dairy cattle.

FDA page: Open in Animal Drugs @ FDA

Species: Beef calves • Dairy calves
Composition / specifications
Each tablet contains 250 of oxytetracycline hydrochloride
Cattle (beef and dairy calves)
Indication

For treatment of bacterial enteritis caused by Salmonella typhimurium and Escherichia coli (colibacillosis) and bacterial pneumonia (shipping fever complex, pasteurellosis) caused by Pasteurella multocida.

Dosage

Orally administer 2 tablets per 100 lb of body weight every 12 hours (10 mg/lb of body weight daily in divided doses) for up to 4 consecutive days. Dosage should continue until the animal returns to normal and for 24-48 hours after symptoms have subsided. Treatment should not exceed 4 consecutive days.

Limitations
Indication

For control of bacterial enteritis caused by Salmonella typhimurium and Escherichia coli (colibacillosis) and bacterial pneumonia (shipping fever complex, pasteurellosis) caused by Pasteurella multocida.

Dosage

Orally administer 1 tablet per 100 lb of body weight every 12 hours (5 mg/lb of body weight daily in divided doses) for up to 4 consecutive days. Dosage should continue until the animal returns to normal and for 24-48 hours after symptoms have subsided. Treatment should not exceed 4 consecutive days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Beef • Dairy, non-lactating
Composition / specifications
300 mg oxytetracycline and 20 mg flunixin base as flunixin meglumine per mL.
Cattle (Beef, Non-Lactating Dairy, Calves, Yearlings)
Indication
For the treatment of bacterial pneumonia associated with Pasteurella spp. and for the control of associated pyrexia in beef and non-lactating dairy cattle
Dosage
Administer once as an intramuscular or subcutaneous injection of 1 mL per 22 pounds (lb) body weight (BW) (13.6 mg oxytetracycline and 0.9 mg flunixin per lb BW) where retreatment of calves and yearlings for bacterial pneumonia is impractical due to husbandry conditions, such as cattle on range, or where their repeated restraint is inadvisable
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. For intramuscular or subcutaneous use in beef and non-lactating dairy cattle, calves and yearlings. Not for use in female dairy cattle 20 months of age or older, including dry dairy cows, bulls intended for breeding, and calves intended to be processed for veal. Do not use in animals showing hypersensitivity to either flunixin meglumine or oxytetracycline.

FDA page: Open in Animal Drugs @ FDA

Species: Honey Bees • Breeding • No use class stated or implied • Beef • Calves • Dairy, non-lactating • Not laying eggs for human consumption • Excluding turkeys producing eggs for human consumption • Lobster • Sheep, No Use Class Stated Or Implied
Composition / specifications
Type A medicated articles containing 50 grams oxytetracycline (from oxytetracycline quaternary salt) equivalent to oxytetracycline hydrochloride per pound
Chickens
Indication
For reduction of mortality due to air sacculitis (air-sac infection) caused by E. coli susceptible to oxytetracycline.
Dosage
500 grams per ton of feed.
Limitations

Feed continuously for 5 days. Do not administer to chickens producing eggs for human consumption. Withdraw 24 hours before slaughter. Do not use in low-calcium feed containing less than 0.55% dietary calcium. Use in such feeds may result in violative residues.

Indication
For control of chronic respiratory disease (CRD) and air sac infection caused by M. gallisepticum and Escherichia coli susceptible to oxytetracycline.
Dosage
400 grams per ton of feed.
Limitations

Feed continuously for 7 to 14 days. Do not administer to chickens producing eggs for human consumption. Do not use in low-calcium feed containing less than 0.55% dietary calcium. Use in such feeds may result in violative residues.

Indication
Control of infectious synovitis caused by Mycoplasma synoviae; control of fowl cholera caused by Pasteurella multocida susceptible to oxytetracycline.
Dosage
100 - 200 grams per ton of feed.
Limitations

Feed continuously for 7 to 14 days. Do not administer to chickens producing eggs for human consumption. Do not use in low-calcium feed containing less than 0.55% dietary calcium. Use in such feeds may result in violative residues.

Turkeys
Indication
For control of complicating bacterial organisms associated with bluecomb (transmissible enteritis; coronaviral enteritis) susceptible to oxytetracycline.
Dosage
25 milligrams per pound of body weight.
Limitations

Feed continuously for 7 to 14 days. Withdraw 5 days before slaughter. Do not administer to turkeys producing eggs for human consumption.

Indication
For control of hexamitiasis caused by Hexamita meleagridis susceptible to oxytetracycline.
Dosage
100 grams per ton of feed.
Limitations

Feed continuously for 7 to 14 days. Do not administer to turkeys producing eggs for human consumption.

Indication
For control of infectious synovitis caused by M. synoviae susceptible to oxytetracycline.
Dosage
200 grams per ton of feed.
Limitations

Feed continuously for 7 to 14 days. Withdraw 5 days before slaughter. Do not administer to turkeys producing eggs for human consumption.

Swine
Indication
For treatment of bacterial enteritis caused by E. coli and Salmonella choleraesuis susceptible to oxytetracycline and treatment of bacterial pneumonia caused by P. multocida susceptible to oxytetracycline.
Dosage
10 milligrams per pound of body weight.
Limitations

Feed continuously for 7 to 14 days. 

Swine (Breeding)
Indication

For control and treatment of leptospirosis (reducing the incidence of abortion and shedding of leptospirae) caused by Leptospira pomona susceptible to oxytetracycline.

Dosage
10 milligrams per pound of body weight.
Limitations

Feed continuously for not more than 14 days.  

Cattle (beef and non-lactating dairy: growing cattle over 400 pounds)
Indication

For the reduction of the incidence of liver abscesses.

Dosage

75 milligrams per head per day.

Limitations

Feed continuously.

Cattle (calves including veal calves, beef, and non-lactating dairy)
Indication

Treatment of bacterial enteritis caused by E. coli.

Dosage

10 milligrams per pound of body weight daily.

Limitations

Feed continuously for 7 to 14 days. In milk replacer or starter feed. Withdraw 0 days before slaughter. When used in milk replacers, the treatment claim (10 mg/lb) is limited to bacterial enteritis caused by E. coli only.

Indication

Treatment of bacterial enteritis caused by E. coli and bacterial pneumonia (shipping fever complex) caused by P. multocida susceptible to oxytetracycline).

Dosage

10 milligrams per pound of body weight daily.

Limitations

Feed continuously for 7 to 14 days. Withdraw 0 days before slaughter.

Indication
For prevention and treatment of the early stages of shipping fever complex.
Dosage
0.5 - 2.0 grams per head per day in feed.
Limitations

Feed 3 to 5 days before and after arrival in feedlots. 

Sheep
Indication

For treatment of bacterial enteritis caused by E. coli and bacterial pneumonia caused by P. multocida susceptible to oxytetracycline.

Dosage

10 milligrams per pound of body weight daily.

Limitations

Feed continuously for 7 to 14 days. Withdraw 5 days before slaughter.

Lobsters
Indication
For control of gaffkemia caused by Aerococcus viridans.
Dosage
1 gram per pound medicated feed.
Limitations

Administer as sole ration for 5 consecutive days. Withdraw medicated feed 30 days before harvesting lobsters.

Honey bees
Indication

Control of American Foulbrood caused by Bacillus larvae, and European foulbrood caused by Streptococcus pluton susceptible to oxytetracycline.

Dosage

200 milligrams per colony.

Limitations

Remove at least 6 weeks prior to main honey flow.

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied
Composition / specifications
Type A medicated article containing 10 grams per pound carbadox. Type A medicated articles containing 10, 20, 30, 50, 100, or 200 grams per pound oxytetracycline.
Swine
Indication

For treatment of bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis susceptible to oxytetracycline and treatment of bacterial pneumonia caused by Pasteurella multocida susceptible to oxytetracycline and increased rate of weight gain and improved feed efficiency.

Dosage

10 to 25 grams carbadox and approximately 400 grams of chlortetracycline (varying with body weight and feed consumption to provide 10 milligrams of chlortetracycline per pound of body weight daily).

Limitations

Feed continuously as the sole ration for 7 to 14 days. Not for use in pregnant swine or swine intended for breeding purposes. Do not mix in feeds containing bentonite. Do not feed to swine within 42 days of slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Fish, Finfish, Fry And Fingerlings
Composition / specifications
Each gram of soluble powder contains 366 milligrams (mg) of oxytetracycline hydrochloride.
Finfish
Indication
For skeletal marking of finfish fry and fingerlings.
Dosage
Immerse fish in a solution containing 200 to 700 mg oxytetracycline hydrochloride (buffered) per liter of water for 2 to 6 hours.
Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Honey Bees • Breeding • No use class stated or implied • Beef • Calves • Dairy, females Under 20 months of age • Growing • Not laying eggs for human consumption • Excluding turkeys producing eggs for human consumption • Sheep, No Use Class Stated Or Implied
Composition / specifications
Each 18.1 grams of powder contains 1 gram of oxytetracycline hydrochloride (packet: 6.4 oz; pails: 2 and 5 lb)
Chickens
Indication

Control of chronic respiratory disease (CRD) and air sac infections caused by Mycoplasma gallisepticum and E. coli susceptible to oxytetracycline; control of fowl cholera caused by Pasteurella multocida susceptible to oxytetracycline.

Dosage
400 to 800 milligrams per gallon of drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.

Indication

Control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.

Dosage

200 to 400 milligrams per gallon of drinking water.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.

Turkeys
Indication

Control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.

Dosage
400 milligrams per gallon of drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of oxytetracycline. Use as a sole source of drinking water. Do not use in birds producing eggs for human consumption. Withdraw 5 days prior to slaughter.

Indication

Control of hexamitiasis caused by Hexamita meleagridis susceptible to oxytetracycline.

Dosage

200 - 400 milligrams per gallon of drinking water.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of oxytetracycline. Use as a sole source of drinking water. Do not use in birds producing eggs for human consumption. Withdraw 5 days prior to slaughter.

Turkeys (growing)
Indication
Control of complicating bacterial organisms associated with bluecomb (transmissible enteritis, coronaviral enteritis) susceptible to oxytetracycline.
Dosage

25 milligrams per pound of body weight.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of oxytetracycline. Use as a sole source of drinking water. Do not use in birds producing eggs for human consumption. Withdraw 5 days prior to slaughter.

Swine
Indication

Control and treatment of bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis and bacterial pneumonia caused by Pasteurella multocida susceptible to oxytetracycline.

Dosage
10 milligrams per pound of body weight in drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer up to 14 days. Do not use for more than 14 consecutive days. Use as a sole source of oxytetracycline. Zero-day slaughter withdrawal in swine.

Swine (breeding stock)
Indication

Control and treatment of leptospirosis (reducing the incidence of abortions and shedding of leptospira) caused by Leptospira pomona susceptible to oxytetracycline.

Dosage

10 milligrams per pound of body weight.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer up to 14 days. Do not use for more than 14 consecutive days. Use as a sole source of oxytetracycline. Zero–day slaughter withdrawal in swine.

Cattle (calves, beef and nonlactating dairy)
Indication

Control and treatment of bacterial enteritis caused by E. coli and bacterial pneumonia (shipping fever complex) caused by P. multocida susceptible to oxytetracycline.

Dosage
10 milligrams per pound of body weight in drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer up to 14 days. Do not use for more than 14 consecutive days. Use as sole source of oxytetracycline. Do not administer this product with milk or milk replacers. Administer 1 hour before or 2 hours after feeding milk or milk replacers. Withdraw 5 days prior to slaughter. A milk discard period has not been established for this product in lactating dairy cattle. Do not use in female dairy cattle 20 months of age or older.

Sheep
Indication

Control and treatment of bacterial enteritis caused by E. coli and bacterial pneumonia (shipping fever complex) caused by P. multocida susceptible to oxytetracycline.

Dosage
10 milligrams per pound of body weight in drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer up to 14 days. Do not use for more than 14 consecutive days. Use as a sole source of oxytetracycline. Withdraw 5 days prior to slaughter.

Honey bees
Indication

Control of American foul brood caused by Paenibacillus larvae susceptible to oxytetracycline.

Dosage

200 milligrams per colony, administered via either an 1:1 sugar syrup (equal parts of sugar and water weight to weight) or dusting with a powdered sugar mixture.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. The drug is administered in 3 applications of sugar syrup or 3 dustings at 4- to 5- days intervals. The drug should be fed early in the spring or fall and consumed by the bees before main honey flow begins to avoid contamination of production honey. Remove at least 6 weeks prior to main honey flow. Dusting of uncapped brood cells has been reported to cause death of larval honey bees. Do not dust uncapped brood cells.

FDA page: Open in Animal Drugs @ FDA

Species: Honey Bees • Fish, Finfish, Fry And Fingerlings • Breeding • No use class stated or implied • Beef • Calves • Dairy, females Under 20 months of age • Growing • Not laying eggs for human consumption • Excluding turkeys producing eggs for human consumption • Sheep, No Use Class Stated Or Implied
Composition / specifications
Each 1.32 grams of powder contains 1 gram of OTC HCl (packet: 4.78 ounce and 9.6 ounce; pails 2 and 5 pounds)
Chickens
Indication

Control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.

Dosage
200 to 400 milligrams per gallon of drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.

Indication

Control of chronic respiratory disease (CRD) and air sac infections caused by Mycoplasma gallisepticum and E. coli susceptible to oxytetracycline; control of fowl cholera caused by Pasteurella multocida susceptible to oxytetracycline.

Dosage
400 to 800 milligrams per gallon of drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.

Turkeys
Indication

For the control of hexamitiasis caused by Hexamita meleagridis susceptible to oxytetracycline.

Dosage

200 – 400 milligrams per gallon of drinking water.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of oxytetracycline. Use as a sole source of drinking water. Do not use in birds producing eggs for human consumption. Withdraw 5 days before slaughter.

Indication

Control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.

Dosage
400 milligrams per gallon of drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of oxytetracycline. Use as a sole source of drinking water. Do not use in birds producing eggs for human consumption. Withdraw 5 days before slaughter.

Turkeys (growing)
Indication

Control of complicating bacterial organisms associated with bluecomb (transmissible enteritis, coronaviral enteritis) susceptible to oxytetracycline.

Dosage
25 milligrams per pound of body weight in drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of oxytetracycline. Use as a sole source of drinking water. Do not use in birds producing eggs for human consumption. Withdraw 5 days before slaughter.

Swine
Indication

Control and treatment of bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis and bacterial pneumonia caused by Pasteurella multocida susceptible to oxytetracycline.

Dosage
10 milligrams per pound of body weight in drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer up to 14 days. Do not use for more than 14 consecutive days. Use as a sole source of oxytetracycline. Zero-day slaughter withdrawal in swine.

Swine (breeding stock)
Indication

Control and treatment of leptospirosis (reducing the incidence of abortions and shedding of leptospira) caused by Leptospira pomona susceptible to oxytetracycline.

Dosage

10 milligrams per pound of body weight.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer up to 14 days. Do not use for more than 14 consecutive days. Use as a sole source of oxytetracycline. Zero–day slaughter withdrawal in swine.

Cattle (calves, beef, and nonlactating dairy)
Indication

Control and treatment of bacterial enteritis caused by E. coli and bacterial pneumonia (shipping fever complex) caused by P. multocida susceptible to oxytetracycline.

Dosage
10 milligrams per pound of body weight in drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer up to 14 days. Do not use for more than 14 consecutive days. Use as sole source of oxytetracycline. Do not administer this product with milk or milk replacers. Administer 1 hour before or 2 hours after feeding milk or milk replacers. Withdraw 5 days prior to slaughter. A milk discard period has not been established for this product in lactating dairy cattle. Do not use in female dairy cattle 20 months of age or older.

Sheep
Indication

Control and treatment of bacterial enteritis caused by E. coli and bacterial pneumonia (shipping fever complex) caused by P. multocida susceptible to oxytetracycline.

Dosage
10 milligrams per pound of body weight in drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer up to 14 days. Do not use for more than 14 consecutive days. Use as a sole source of oxytetracycline. Withdraw 5 days prior to slaughter.

Honey bees
Indication

Control of American foul brood caused by Paenibacillus larvae susceptible to oxytetracycline.

Dosage

200 milligrams per colony, administered via either a 1:1 sugar syrup (equal parts of sugar and water weight to weight) or dusting with a powdered sugar mixture.

Limitations
Finfish fry and fingerlings
Indication
For skeletal marking of finfish fry and fingerlings.
Dosage

Immerse fish in a solution containing 200 to 700 mg oxytetracycline hydrochloride (buffered) per liter of water for 2 to 6 hours.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Broilers
Composition / specifications
Type A medicated article containing 30 or 60 grams of salinomycin activity per pound (as salinomycin sodium biomass). Type A medicated article containing 100 grams per pound oxytetracycline (from oxytetracycline quaternary salt).
Chickens (broiler)
Indication

For chickens as an aid in the reduction of mortality due to air-sacculitis (air-sac infection) caused by Escherichia coli sensitive to oxytetracycline and for the prevention of coccidiosis caused by Eimeria necatrix, E. tenella, E. acervulina, E. brunetti E. mivati, and E. maxima.

Dosage

500 grams oxytetracycline and 40 to 60 grams salinomycin sodium per ton of feed of Type C medicated feed.

Limitations

Feed for 5 days as sole ration. Treat at first clinical signs of disease. Do not feed to laying chickens. Do not use in low-calcium feed containing less than 0.55% dietary calcium. Use in such feeds may result in violative residues. Withdraw 24 hours before to slaughter. Do not use in feeds containing pellet binders. May be fatal if accidentally fed to adult turkeys or to horses.

FDA page: Open in Animal Drugs @ FDA

Species: Broilers
Composition / specifications
Type A medicated article containing 30 grams per pound robenidine hydrochloride. Type A medicated article containing 100 grams per pound oxytetracycline (from oxytetracycline quaternary salt).
Chickens (broilers)
Indication

For chickens for control of chronic respiratory disease (CRD) and air sac infection caused by Mycoplasma gallisepticum and Escherichia coli susceptible to oxytetracycline, and as an aid in the prevention of coccidiosis caused by Eimeria necatrix, Eimeria tenella, Eimeria acervulina, Eirmeria brunetti, Eimeria mivati, and Eimeria maxima.

Dosage

30 grams robenidine hydrochloride and 400 grams oxytetracycline per ton of Type C medicated feed.

Limitations

Feed continuously for 7 to 14 days. Do not feed to chickens producing eggs for human consumption. Do not use in low-calcium feed containing less than 0.55% dietary calcium. Use in such feeds may result in violative residues. Withdraw 5 days before slaughter. Feed must be used within 50 days from date of manufacture. Do not use in feeds containing bentonite.

FDA page: Open in Animal Drugs @ FDA

Species: Broilers
Composition / specifications
Type A medicated article containing 30 or 60 grams of salinomycin activity per pound (as salinomycin sodium biomass). Type A medicated article containing 100 grams per pound oxytetracycline (from oxytetracycline quaternary salt).
Chickens (broilers)
Indication

As an aid in the reduction of mortality due to air-sacculitis (air-sac infection) caused by Escherichia coli sensitive to oxytetracycline; for the prevention of coccidiosis caused by Eimeria necatrix, E. tenella, E. acervulina, E. brunetti E. mivati, and E. maxima.

Dosage

500 grams oxytetracycline and 40 to 60 grams salinomycin sodium per ton of feed of Type C medicated feed.

Limitations

Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian. Feed for 5 days as sole ration. Treat at first clinical signs of disease. Do not feed to laying chickens. Do not use in low-calcium feed containing less than 0.55% dietary calcium. Use in such feeds may result in violative residues. Withdraw 24 hours prior to slaughter. Do not use in feeds containing pellet binders. May be fatal if accidentally fed to adult turkeys or to horses.

FDA page: Open in Animal Drugs @ FDA

Species: Fish, Finfish, Fry And Fingerlings
Composition / specifications
Each 2.73 grams of powder contains 1 gram of OTC HCl (packets: 2.46 and 9.87 ounce; pail: 3.09 pound). Each gram of powder contains 366 milligrams (mg) of oxytetracycline hydrochloride.
Finfish
Indication
For skeletal marking of finfish fry and fingerlings
Dosage

Immerse fish in a solution containing 200 to 700 mgoxytetracycline hydrochloride (buffered) per liter of water for 2 to 6 hours.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian

FDA page: Open in Animal Drugs @ FDA

Species: Breeding • No use class stated or implied • Growing • Not laying eggs for human consumption • Excluding turkeys producing eggs for human consumption
Composition / specifications
4.78 oz. (135.5 g) pouch: each packet contains 102.4 grams of oxytetracycline hydrochloride. 5 lb. (2.27 kg) pail: each pail contains 1.715 kilograms of oxytetracycline hydrochloride. 3.09 lb. (1400 g) pouch: each packet contains 512 grams of oxytetracycline hydrochloride. 9.87 oz. (280 g) packet: each packet contains 102.4 grams of oxytetracycline hydrochloride
Chickens
Indication

For the control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.

Dosage

Administer 200 to 400 milligrams of powder per gallon of drinking water.

Limitations

Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption. Use as the sole source of oxytetracycline. Federal Law restricts this drug to use by or on the order of a licensed veterinarian.

Indication

For the control of chronic respiratory disease (CRD) and air sac infections caused by Mycoplasma gallisepticum and E. coli susceptible to oxytetracycline; for the control of fowl cholera caused by Pasteurella multocida susceptible to oxytetracycline.

Dosage

Administer 400 to 800 milligrams of powder per gallon of drinking water.

Limitations

Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption. Use as the sole source of oxytetracycline. Federal Law restricts this drug to use by or on the order of a licensed veterinarian.

Turkeys
Indication

For the control of hexamitiasis caused by Hexamita meleagridis susceptible to oxytetracycline.

Dosage

Administer 200 to 400 milligrams of powder per gallon of drinking water.

Limitations

Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption. Use as the sole source of oxytetracycline. Federal Law restricts this drug to use by or on the order of a licensed veterinarian.

Indication

For the control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.

Dosage

Administer 400 milligrams of powder per gallon of drinking water.

Limitations

Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption. Use as the sole source of oxytetracycline. Federal Law restricts this drug to use by or on the order of a licensed veterinarian.

Turkeys (growing)
Indication

For the control of complicating bacterial organisms associated with bluecomb (transmissible enteritis, coronaviral enteritis) susceptible to oxytetracycline.

Dosage

Administer 25 milligrams per pound of body weight in drinking water.

Limitations

Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption. Use as the sole source of oxytetracycline. Federal Law restricts this drug to use by or on the order of a licensed veterinarian.

Swine
Indication

For the control and treatment of bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis and bacterial pneumonia caused by Pasteurella multocida susceptible to oxytetracycline.

Dosage

Administer 10 milligrams per pound of body weight daily in drinking water.

Limitations

Prepare a fresh solution daily. Use as the sole source of oxytetracycline. Administer up to 5 days; do not use for more than 5 consecutive days. Use as sole source of drinking water. Do not mix this product directly with milk or milk replacers. Administer one hour before or two hours after feeding milk or milk replacers. Withdraw zero days prior to slaughter. Federal Law restricts this drug to use by or on the order of a licensed veterinarian.

Swine (breeding stock)
Indication

For the control and treatment of leptospirosis (reducing the incidence of abortions and shedding of leptospira) caused by Leptospira pomona susceptible to oxytetracycline.

Dosage

Administer 10 milligrams per pound of body weight daily in drinking water.

Limitations

Prepare a fresh solution daily. Use as the sole source of oxytetracycline. Administer up to 5 days; do not use for more than 5 consecutive days. Use as sole source of drinking water. Do not mix this product directly with milk or milk replacers. Administer one hour before or two hours after feeding milk or milk replacers. Withdraw zero days prior to slaughter. Federal Law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Growing • Not laying eggs for human consumption • Excluding turkeys producing eggs for human consumption
Composition / specifications
Each 4.2 gram of powder contains 1 gram of oxytetracycline hydrochloride.
Chickens
Indication

Control of chronic respiratory disease (CRD) and air sac infections caused by Mycoplasma gallisepticum and E. coli and fowl cholera caused by Pasteurella multocida.

Dosage

400 to 800 milligrams per gallon of drinking water. 

Limitations

Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.

Indication
Control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.
Dosage

200 to 400 milligrams per gallon of drinking water. 

Limitations

Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.

Turkeys
Indication
Control of hexamitiasis caused by Hexamita meleagridis susceptible to oxytetracycline.
Dosage

200 to 400 milligrams per gallon of drinking water. 

Limitations

Administer for 7 to 14 days; do not slaughter for food within 4 days of treatment; not for use in turkeys producing eggs for human consumption; prepare a fresh solution daily; use as the sole source of tetracycline.

Indication
Control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.
Dosage

400 milligrams per gallon of drinking water. 

Limitations

Administer for 7 to 14 days; do not slaughter for food within 4 days of treatment; not for use in turkeys producing eggs for human consumption; prepare a fresh solution daily; use as the sole source of tetracycline.

Indication

Control of complicating bacterial organisms associated with bluecomb (transmissible enteritis, coronaviral enteritis).

Dosage

25 mg/lb of body weight per day in drinking water.

Limitations

Administer for 7 to 14 days; do not slaughter for food within 4 days of treatment; not for use in turkeys producing eggs for human consumption; prepare a fresh solution daily; use as the sole source of tetracycline.

FDA page: Open in Animal Drugs @ FDA

Species: Honey Bees • Fish, Finfish, Fry And Fingerlings • Breeding • No use class stated or implied • Beef • Calves • Dairy, females Under 20 months of age • Growing • Not laying eggs for human consumption • Excluding turkeys producing eggs for human consumption • Sheep, No Use Class Stated Or Implied
Composition / specifications
Each 677.5 gram packet contains 512 grams of oxytetracycline hydrochloride (OTC HCL)(packet 23.9 oz).
Chickens
Indication
Control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.
Dosage
200 to 400 milligrams per gallon of drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.

Indication
Control of chronic respiratory disease (CRD) and air sac infections caused by Mycoplasma gallisepticum and E. coli susceptible to oxytetracycline; control of fowl cholera caused by Pasteurella multocida susceptible to oxytetracycline.
Dosage
400 to 800 milligrams per gallon of drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.

Turkeys
Indication

Control of hexamitiasis caused by Hexamita meleagridis susceptible to oxytetracycline.

Dosage
200 - 400 milligrams per gallon of drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of oxytetracycline. Use as a sole source of drinking water. Do not use in birds producing eggs for human consumption. Zero day slaughter withdrawal in turkeys.

Indication
Control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.
Dosage
400 milligrams per gallon of drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of oxytetracycline. Use as a sole source of drinking water. Do not use in birds producing eggs for human consumption. Zero day slaughter withdrawal in turkeys.

Turkeys (growing)
Indication
Control of complicating bacterial organisms associated with bluecomb (transmissible enteritis, coronaviral enteritis) susceptible to oxytetracycline.
Dosage

25 milligrams per pound of body weight.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of oxytetracycline. Use as a sole source of drinking water. Do not use in birds producing eggs for human consumption. Zero day slaughter withdrawal in turkeys.

Swine
Indication

Control and treatment of bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis and bacterial pneumonia caused by Pasteurella multocida susceptible to oxytetracycline.

Dosage
10 milligrams per pound of body weight daily in drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Administer up to 5 days. Do not use for more than 5 consecutive days. Zero day slaughter withdrawal in swine.

Cattle (calves, beef, and nonlactating dairy)
Indication
Control and treatment of bacterial enteritis caused by E. coli and bacterial pneumonia (shipping fever complex) caused by P. multocida susceptible to oxytetracycline.
Dosage
10 milligrams per pound of body weight daily in drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer up to 5 days. Do not use for more than 5 consecutive days. Use as sole source of oxytetracycline. Do not administer this product with milk or milk replacers. Administer 1 hour before or 2 hours after feeding milk or milk replacers. Withdraw 5 days prior to slaughter. A milk discard period has not been established for this product in lactating dairy cattle. Do not use in female dairy cattle 20 months of age or older.

Swine (breeding stock)
Indication

Control and treatment of leptospirosis (reducing the incidence of abortions and shedding of leptospira) caused by Leptospira pomona susceptible to oxytetracycline.

Dosage

10 milligrams per pound of body weight.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Administer up to 5 days. Do not use for more than 5 consecutive days. Zero day slaughter withdrawal in swine.

Sheep
Indication
Control and treatment of bacterial enteritis caused by E. coli and bacterial pneumonia (shipping fever complex) caused by P. multocida susceptible to oxytetracycline.
Dosage
10 milligrams per pound of body weight in drinking water.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer up to 5 days. Do not use for more than 5 consecutive days. Use as a sole source of oxytetracycline. Withdraw 5 days prior to slaughter.

Honey Bees
Indication

Control of American foul brood caused by Paenibacillus larvae susceptible to oxytetracycline.

Dosage
200 milligrams per colony, administered via either a 1:1 sugar syrup (equal parts of sugar and water weight to weight) or dusting with a powdered sugar mixture.
Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. The drug is administered in 3 applications of sugar syrup or 3 dustings at 4- to 5- days intervals. The drug should be fed early in the spring or fall and consumed by the bees before main honey flow begins to avoid contamination of production honey. Remove at least 6 weeks prior to main honey flow. Dusting of uncapped brood cells has been reported to cause death of larval honey bees. Do not dust uncapped brood cells.

Finfish fry and fingerlings
Indication

For skeletal marking of finfish fry and fingerlings.

Dosage

Immerse fish in a solution containing 200 to 700 mg oxytetracycline hydrochloride (buffered) per liter of water for 2 to 6 hours.

Limitations

Federal Law restricts this drug to use by or on the order of a licensed veterinarian. For skeletal marking of finfish fry and fingerlings.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
The drug contains 100 milligrams of oxytetracycline hydrochloride and 2 percent lidocaine in each milliliter of sterile aqueous solution.
Dogs
Indication
The drug is indicated for use in the treatment of diseases of dogs caused by pathogens sensitive to oxytetracycline hydrochloride including treatment for the following conditions in dogs caused by susceptible microorganisms: Bacterial infections of the urinary tract caused by Hemolytic Staphylococcus species, Streptococcus species, Bacterial pulmonary infections caused by Brucella bronchiseptica, Streptococcus pyogenes, Staphylococcus aureus, secondary bacterial infections caused by Micrococcus pyogenes var. albus, Brucella bronchiseptica, Streptococcus species.
Dosage
The drug is administered intramuscularly at a recommended daily dosage to dogs at 5 milligrams per pound of body weight administered in divided doses at 6 to 12 hour intervals. Therapy should be continued for at least 24 hours after all symptoms have subsided.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Cattle, Dairy, Not Lactating • Swine, No Use Class Stated Or Implied • Swine, Sows With Litters Or About To Farrow • Cattle, Beef
Composition / specifications
200 milligrams/milliliter
Sows
Indication
As an aid in control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by E. coli.
Dosage
3 milligrams per pound of body weight intramuscularly once.
Limitations
Administer intramuscularly. Do not inject more than 5 mL per site in adult swine. Discontinue treatment at least 28 days prior to slaughter.
Swine
Indication
Where re-treatment for pneumonia is impractical.
Dosage
9 milligrams per pound of body weight as a single dosage.
Limitations
Administer intramuscularly. Do not inject more than 5 mL per site in adult swine. Discontinue treatment at least 28 days prior to slaughter.
Indication
For treatment of bacterial enteritis (scours, colibacillosis) caused by E. coli, pneumonia caused by Pasteurella multocida, and leptospirosis caused by Leptospira pomona.
Dosage
3 to 5 milligrams of oxytetracycline per pound of body weight per day.
Limitations
Administer intramuscularly. Do not inject more than 5 mL per site in adult swine. Discontinue treatment at least 28 days prior to slaughter.
Cattle (beef,dairy excluding lactating animals, and calves, including preruminating veal calves)
Indication
Where retreatment of calves and yearlings for bacterial pneumonia is impractical, for treatment of infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis, or where retreatment for anaplasmosis is impractical.
Dosage
9 milligrams per pound of body weight intramuscularly or subcutaneously as a single dose.
Limitations
Administer intramuscularly or intravenously. Exceeding the highest recommended level of drug per pound of bodyweight per day, administering more than the recommended number of treatments, and/or exceeding 10 mL intramuscularly or subcutaneously per injection site may result in antibiotic residues beyond the withdrawal time. Rapid intravenous administration in cattle may result in animal collapse. Oxytetracycline should be administered intravenously slowly over a period of at least 5 minutes. Discontinue treatment at least 28 days prior to slaughter. Not for use in lactating dairy animals. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Indication
For treatment of anaplasmosis, severe foot-rot and advanced cases of other indicated diseases.
Dosage
5 milligrams per pound of body weight per day.
Limitations
Administer intramuscularly, subcutaneously, or intravenously. Exceeding the highest recommended level of drug per pound of bodyweight per day, administering more than the recommended number of treatments, and/or exceeding 10 mL intramuscularly or subcutaneously per injection site may result in antibiotic residues beyond the withdrawal time. Rapid intravenous administration in cattle may result in animal collapse. Oxytetracycline should be administered intravenously slowly over a period of at least 5 minutes. Discontinue treatment at least 28 days prior to slaughter. Not for use in lactating dairy animals.
Indication
For treatment of pneumonia and shipping fever complex associated with Pasteurella species and Haemophilus species, foot-rot and diphtheria caused by Fusobacterium necrophorum, bacterial enteritis (scours) caused by Escherichia coli, wooden tongue caused by Actinobacillus lignieresii, leptospirosis caused by Leptospira pomona, wound infections and acute metritis caused by Staphylococcus species and Streptococcus species, and anthrax caused by Bacillus anthracis.
Dosage
3 to 5 milligrams of oxytetracycline per pound of body weight per day.
Limitations
Administer intramuscularly, subcutaneously, or intravenously. Exceeding the highest recommended level of drug per pound of bodyweight per day, administering more than the recommended number of treatments, and/or exceeding 10 mL intramuscularly or subcutaneously per injection site may result in antibiotic residues beyond the withdrawal time. Rapid intravenous administration in cattle may result in animal collapse. Oxytetracycline should be administered intravenously slowly over a period of at least 5 minutes. Discontinue treatment at least 28 days prior to slaughter. Not for use in lactating dairy animals. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied • Sows with litters or about to farrow • Beef • Dairy, non-lactating • Breeders not laying eggs for human consumption • Broilers not laying eggs for human consumption • Excluding turkeys producing eggs for human consumption
Composition / specifications
The drug contains 50 milligrams of oxytetracycline hydrochloride in each milliliter of sterile solution.
Cattle (beef and nonlactating dairy)
Indication
It is used for the treatment of pneumonia and shipping fever complex associated with Pasteurella species and Hemophilus species; foot-rot and diphtheria caused by Spherophorus necrophorus; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresi; leptospirosis caused by Leptospira pomona; wound infections and acute metritis caused by staphylococcal and streptococcal organisms.
Dosage
Administer by intravenous or intramuscular injection at 3 to 5 milligrams of oxytetracycline per pound of body weight per day. In the treatment of severe foot-rot and severe forms of the indicated diseases, a dosage level of 5 milligrams per pound of body weight per day is recommended. If the labeling of the drug bears the statement ``Federal law restricts this drug to use by or on the order of a licensed veterinarian,'' it may include additional directions for use in beef cattle and nonlactating dairy cattle for the treatment of anaplasmosis caused by Anaplasma marginale and anthrax caused by Bacillus anthracis in which case the drug is given at 3 to 5 milligrams of oxytetracycline per pound of body weight per day for anthrax, and at 5 milligrams per pound of body weight per day for anaplasmosis.
Limitations
Treatment of all diseases should be instituted early. Treatment should continue for 24 to 48 hours beyond the remission of disease symptoms, but not exceed a total of 4 consecutive days. If no improvement is noted within 24 to 48 hours, diagnosis and therapy should be reevaluated. When injecting intramuscularly in adult livestock, do not inject more than 10 milliliters at any one site. The volume administered per injection site should be reduced according to age and body size so that 1 or 2 milliliters are injected in smaller animals such as small calves. Intravenous administration is recommended in cattle when daily dosage exceeds 50 milliliters. Treatment must be discontinued at least 22 days prior to slaughter for cattle. When administered intramuscularly to animals within 30 days of slaughter, muscle discoloration may necessitate trimming of the injection site(s) and surrounding tissues during the dressing procedure. Not for use in lactating dairy animals.
Swine
Indication
It is used for the treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli; pneumonia caused by Pasteurella multocida; and leptospirosis caused by Leptospira pomona.
Dosage
Administer by intramuscular injection at 3 to 5 milligrams of oxytetracycline per pound of body weight per day to swine.
Limitations
Treatment of all diseases should be instituted early. Treatment should continue for 24 to 48 hours beyond the remission of disease symptoms, but not exceed a total of 4 consecutive days. If no improvement is noted within 24 to 48 hours, diagnosis and therapy should be reevaluated. When injecting intramuscularly in adult livestock, do not inject more than 10 milliliters at any one site. The volume administered per injection site should be reduced according to age and body size so that 1 or 2 milliliters are injected in smaller animals such as young pigs. Treatment must be discontinued at least 22 days prior to slaughter for swine. When administered intramuscularly to animals within 30 days of slaughter, muscle discoloration may necessitate trimming of the injection site(s) and surrounding tissues during the dressing procedure.
Swine (sows about to farrow or just farrowed).
Indication
Administered to sows as an aid in the control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.
Dosage
Administered to sows at 3 milligrams of oxytetracycline per pound of body weight approximately 8 hours before farrowing or immediately after farrowing. Administer intramuscularly.
Limitations
Treatment of all diseases should be instituted early. Treatment should continue for 24 to 48 hours beyond the remission of disease symptoms, but not exceed a total of 4 consecutive days. If no improvement is noted within 24 to 48 hours, diagnosis and therapy should be reevaluated. When injecting intramuscularly in adult livestock, do not inject more than 10 milliliters at any one site. The volume administered per injection site should be reduced according to age and body size so that 1 or 2 milliliters are injected in smaller animals such as young pigs. Treatment must be discontinued at least 22 days prior to slaughter for swine. When administered intramuscularly to animals within 30 days of slaughter, muscle discoloration may necessitate trimming of the injection site(s) and surrounding tissues during the dressing procedure.
Chickens (broilers and breeding chickens)
Indication
It is used for the treatment of air sacculitis (air-sac disease chronic respiratory disease) caused by Mycoplasma gallisepticum and Escherichia coli; fowl cholera caused by Pasteurella multocida; infectious sinusitis caused by Mycoplasma gallisepticum; and infectious synovitis caused by Mycoplasma synoviae.
Dosage
Administered subcutaneously to chickens 1 day to 2 weeks of age at 6.25 milligrams of oxytetracycline per bird per day diluted with 1 part of the drug to 3 parts of sterile water; to chickens 2 to 4 weeks of age using the same diluted product at 12.5 milligrams of oxytetracycline per bird; to chickens 4 to 8 weeks of age without dilution at 25 milligrams of oxytetracycline per bird; to chickens 8 weeks of age (broilers and light pullets) at 50 milligrams of oxytetracycline per bird; to adult chickens at 100 milligrams of oxytetracycline per bird.
Limitations
Treatment of all diseases should be instituted early. Treatment should continue for 24 to 48 hours beyond the remission of disease symptoms, but not exceed a total of 4 consecutive days. If no improvement is noted within 24 to 48 hours, diagnosis and therapy should be reevaluated. Treatment must be discontinued at least 5 days prior to slaughter for chickens. Do not administer to laying hens unless the eggs are used for hatching only.
Turkeys
Indication
It is used for the treatment of air sacculitis (air-sac disease chronic respiratory disease) caused by Mycoplasma gallisepticum and Escherichia coli; fowl cholera caused by Pasteurella multocida; infectious sinusitis caused by Mycoplasma gallisepticum; and infectious synovitis caused by Mycoplasma synoviae.
Dosage
Administered subcutaneously to turkeys 1 day to 2 weeks of age and 2 to 4 weeks of age at the same dosage as chickens; to turkeys 4 to 6 weeks of age at 50 milligrams of oxytetracycline as the undiluted product per bird; to turkeys 6 to 9 weeks of age at 100 milligrams of oxytetracycline per bird; to turkeys 9 to 12 weeks of age at 150 milligrams of oxytetracycline per bird; to turkeys 12 weeks of age and older at 200 milligrams of oxytetracycline per bird. In light turkey breeds, no more than 25 milligrams per pound of body weight is administered. For the treatment of infectious sinusitis in turkeys, 1/4 to 1/2 milliliter of the drug is injected directly into each swollen sinus depending upon the age of the bird and the severity of the condition. At the time that the sinuses are treated, the drug should also be administered subcutaneously to the birds according to the dosage schedule stated above for chickens and turkeys. If refilling of the sinuses occurs, the treatment may be repeated in 5 to 7 days.
Limitations
Treatment of all diseases should be instituted early. Treatment should continue for 24 to 48 hours beyond the remission of disease symptoms, but not exceed a total of 4 consecutive days. If no improvement is noted within 24 to 48 hours, diagnosis and therapy should be reevaluated. Treatment must be discontinued at least 5 days prior to slaughter for turkeys. Do not administer to laying hens unless the eggs are used for hatching only.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
The drug contains 50 or 100 milligrams of oxytetracycline hydrochloride and 2 percent lidocaine in each milliliter of sterile aqueous solution.
Dogs
Indication
The drug is indicated for use in the treatment of diseases of dogs caused by pathogens sensitive to oxytetracycline hydrochloride including treatment for the following conditions in dogs caused by susceptible microorganisms: Bacterial infections of the urinary tract caused by Hemolytic Staphylococcus species, Streptococcus species, Bacterial pulmonary infections caused by Brucella bronchiseptica, Streptococcus pyogenes, Staphylococcus aureus, secondary bacterial infections caused by Micrococcus pyogenes var. albus, Brucella bronchiseptica, Streptococcus species.
Dosage
The drug is administered intramuscularly at a recommended daily dosage to dogs at 5 milligrams per pound of body weight administered in divided doses at 6 to 12 hour intervals. Therapy should be continued for at least 24 hours after all symptoms have subsided.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Breeding Swine • Swine, No Use Class Stated Or Implied • Turkey, Growing • Turkey, Not Laying Eggs For Human Consumption • Chicken, Not Laying Eggs For Human Consumption
Composition / specifications
The drug is a soluble powder distributed in packets (9.87oz and 19.47oz) or pails (5lb). Each 2.73 grams of powder contains 1 gram of oxytetracycline hydrochloride.
Swine (breeding stock)
Indication
Control and treatment of leptospirosis (reducing the incidence of abortions and shedding of leptospira) caused by Leptospira pomona susceptible to oxytetracycline.
Dosage
10 milligrams per pound of body weight daily in drinking water.
Limitations
Prepare a fresh solution daily. Use as sole source of OTC. Administer up to 5 days. Do not use for more than 5 consecutive days.
Turkeys (growing)
Indication
Control of complicating bacterial organisms associated with bluecomb (transmissible enteritis, coronaviral enteritis) susceptible to oxytetracycline.
Dosage
25 milligrams per pound of body weight in drinking water.
Limitations
Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.
Swine
Indication
Control and treatment of bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis and bacterial pneumonia caused by Pasteurella multocida susceptible to oxytetracycline.
Dosage
10 milligrams per pound of body weight daily in drinking water.
Limitations
Prepare a fresh solution daily. Use as sole source of OTC. Administer up to 5 days. Do not use for more than 5 consecutive days.
Chickens
Indication
Control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.
Dosage
200 to 400 milligrams per gallon of drinking water.
Limitations
Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.
Indication
Control of chronic respiratory disease (CRD) and air sac infections caused by Mycoplasma gallisepticum and E. coli susceptible to oxytetracycline; control of fowl cholera caused by Pasteurella multocida susceptible to oxytetracycline.
Dosage
400 to 800 milligrams per gallon of drinking water.
Limitations
Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.
Turkeys
Indication
Control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.
Dosage
400 milligrams per gallon of drinking water.
Limitations
Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.
Indication
Control of hexamitiasis caused by Hexamita meleagridis susceptible to oxytetracycline.
Dosage
200 to 400 milligrams per gallon of drinking water.
Limitations
Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied • Cat, No Use Class Stated Or Implied
Composition / specifications
Each 3-ounce unit of oxytetracycline hydrochloride and hydrocortisone spray contains 300 milligrams of oxytetracycline hydrochloride and 100 milligrams of hydrocortisone with an inert freon propellant such that a 1-second spray treatment will deliver approximately 2.5 milligrams of oxytetracycline hydrochloride and 0.8 milligram of hydrocortisone.
Dogs
Indication
The drug is indicated for relief of discomfort and continued treatment of many allergic, infectious, and traumatic skin conditions. The indications include prevention of bacterial infections in superficial wounds, cuts, and abrasions, treatment of allergic dermatoses, including urticaria, eczemas, insect bites, and cutaneous drug reactions, infections associated with minor burns and wounds, and nonspecific pruritus in dogs.
Dosage
A small quantity should be sprayed on the affected surface by holding the container about 6 inches from the area to be treated and pressing the nozzle for 1 or 2 seconds. Only sufficient spray to coat the skin thinly is necessary. The application of small amounts at frequent intervals will give best results. Before treating animals with long or matted hair, it may be necessary to clip the affected area or spread the hairs to allow the medication to contact the skin surface. Relief may be noted following the first or second treatment; however, treatment should not be discontinued too soon after the initial favorable response has been obtained.
Limitations
Keep away from eyes or other mucous membranes. Avoid inhaling. Use with adequate ventilation. In case of deep or puncture wounds or serious burns, consult a veterinarian.
Cats
Indication
The drug is indicated for relief of discomfort and continued treatment of many allergic, infectious, and traumatic skin conditions. The indications include prevention of bacterial infections in superficial wounds, cuts, and abrasions, treatment of allergic dermatoses, including urticaria, eczemas, insect bites, and cutaneous drug reactions, infections associated with minor burns and wounds, and nonspecific pruritus in cats.
Dosage
A small quantity should be sprayed on the affected surface by holding the container about 6 inches from the area to be treated and pressing the nozzle for 1 or 2 seconds. Only sufficient spray to coat the skin thinly is necessary. The application of small amounts at frequent intervals will give best results. Before treating animals with long or matted hair, it may be necessary to clip the affected area or spread the hairs to allow the medication to contact the skin surface. Relief may be noted following the first or second treatment; however, treatment should not be discontinued too soon after the initial favorable response has been obtained.
Limitations
Keep away from eyes or other mucous membranes. Avoid inhaling. Use with adequate ventilation. In case of deep or puncture wounds or serious burns, consult a veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Chicken, Broilers
Composition / specifications
Type A medicated articles: 10, 20, 30, 40, 50, 100, and 200 grams per pound.
Chickens (broilers)
Indication
As an aid in the reduction of mortality due to air-sacculitis (air-sac-infection) caused by Escherichia coli sensitive to oxytetracycline.
Dosage
500 grams per ton of feed.
Limitations
Feed for 5 days as sole ration. Treat at first clinical signs of disease. Do not feed to laying hens. Withdraw 24 hours prior to slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied • Cat, No Use Class Stated Or Implied
Composition / specifications
The drug is in capsule form with each capsule containing 125 or 250 milligrams of oxytetracycline hydrochloride. Oxytetracycline is the antibiotic substance produced by growth of Streptomyces rimosus or the same antibiotic substance produced by any other means.
Dogs
Indication
It is used in dogs for the treatment of bacterial pneumonia caused by Brucella bronchiseptica, tonsillitis caused by Streptococcus hemolyticus, bacterial enteritis caused by Escherichia coli, urinary tract infections caused by Escherichia coli, and wound infections caused by Staphylococcus aureus. The drug can be used for continuation of compatible antibiotic therapy following parenteral oxytetracycline administration where rapidly attained, sustained antibiotic blood levels are required. The duration of treatment required to obtain favorable response will depend to some extent on the severity and degree of involvement and the susceptibility of the infectious agent. Clinical response to antibiotic therapy usually occurs within 48 to 72 hours. If improvement is not observed within that period, the diagnosis and course of treatment should be reconsidered. To assure adequate treatment, administration of the drug should continue for at least 48 hours following favorable clinical response.
Dosage
The drug is administered orally to dogs at a dosage level of 25- 50 milligrams per pound of body weight per day in divided doses at 12-hour intervals.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Cats
Indication
It is used in cats for the treatment of bacterial pneumonia caused by Brucella bronchiseptica, tonsillitis caused by Streptococcus hemolyticus, bacterial enteritis caused by Escherichia coli, urinary tract infections caused by Escherichia coli, and wound infections caused by Staphylococcus aureus. The drug can be used for continuation of compatible antibiotic therapy following parenteral oxytetracycline administration where rapidly attained, sustained antibiotic blood levels are required. The duration of treatment required to obtain favorable response will depend to some extent on the severity and degree of involvement and the susceptibility of the infectious agent. Clinical response to antibiotic therapy usually occurs within 48 to 72 hours. If improvement is not observed within that period, the diagnosis and course of treatment should be reconsidered. To assure adequate treatment, administration of the drug should continue for at least 48 hours following favorable clinical response.
Dosage
The drug is administered orally to cats at a dosage level of 25- 50 milligrams per pound of body weight per day in divided doses at 12-hour intervals.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Official Documents (FDA)

Direct links to FDA-hosted PDFs and SPL packages (when available).

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For improved feed efficiency, increased rate of weight gain and reduction of the incidence and severity of liver abscesses in beef cattle fed in confinement for slaughter.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat) and reduction of liver condemnation due to liver abscesses in heifers being fed in confinement for slaughter.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For increased rate of weight gain, improved feed efficiency, suppression of estrus (heat) and reduction of liver condemnation due to liver abscesses in heifers being fed in confinement for slaughter.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    This supplement provides for the establishment of a tolerance of 750 parts per billion (ppb) for the sum of tetracycline residues in honey.

  • Summary
    To provide a new indication for the marking of skeletal tissues in finfish fry and fingerlings.
  • Summary
    This supplement establishes a zero-day withdrawal period for swine administered oxytetracycline at 10 mg/lb/day for 14 days.
  • Summary
    One supplemental application is a Category II change to bring the drug product into compliance with the National Academy of Science/National Research Council Drug Efficacy Study Implementation (NAS/NRC/DESI) recommendations. The other supplemental application is a Category II change providing for a tolerance of O.1 ppm in uncooked edible tissues in sheep.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    This supplement establishes a zero-day preslaughter withdrawal period for cattle administered oxytetracycline at 10 mg/lb/day for 14 days.

  • Summary
    This supplement establishes a zero-day withdrawal period for swine administered oxytetracycline at 10 mg/lb/day for 14 days
  • Summary

    For the control and treatment of specific diseases susceptible to oxytetracycline dihyrate pre-mix in swine, calves, cattle, chickens, turkeys, sheep, and honey bees.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    Cattle: For the treatment of pneumonia and shipping fever complex associated with Pasteurella spp. and Haemophilus spp.; infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis; foot rot and diphtheria caused by Fusobacterium necrophorum; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresii; leptospirosis caused by Leptospira pomona; and wound infections and acute metritis caused by strains of staphylococci and streptococci organisms sensitive to oxytetracycline.

    Swine: For the treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli; pneumonia caused by Pasteurella multocida; and leptospirosis caused by Leptospira pomona. In sows, OxyMedâ¿¢ LA is indicated as an aid in the control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    This supplement provides information to address the human food safety and user safety of N-methyl-2-pyrrolidone (NMP) in the formulation of Oxytetracycline Injection, and provides for alignment with Guidance for Industry (GFI) #263, "Recommendations for Sponsors of Medically Important Antimicrobial Drugs Approved for Use in Animals to Voluntarily Bring Under Veterinary Oversight All Products That Continue to be Available Over-the-Counter."

  • Summary

    Oxyshot™ LA is intended for use in the treatment of the following diseases in beef cattle, nonlactating dairy cattle and swine when due to oxytetracycline susceptible organisms.

     Cattle: Oxyshot™ LA is indicated in the treatment of pneumonia and shipping fever complex associated with Pasteurella spp. and Hemophilus spp.; infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis; foot rot and diphtheria caused by Fusobacterium necrophorum; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresii; leptospirosis caused by Leptospira pomona; and wound infections and acute metritis caused by strains of staphylococci and streptococci organisms sensitive to oxytetracycline.
    Swine: In swine, Oxyshot™ LA is indicated in the treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli; pneumonia caused by Pasteurella multocida; and leptospirosis caused by Leptospira pomona. In sows, Oxyshot™ LA is indicated as an aid in the control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.


SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For the control and treatment of the following diseases of beef and dairy calves caused by organisms sensitive to oxytetracycline; bacterial entertis caused by Salmonella typhimurium and Escherichia coli (colibacillosis); bacterial pneumonia (shipping fever complex, pasteurellosis) caused by Pasteurella multocida.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    Beef cattle, dairy cattle, calves, including preruminating (veal) calves: indicated in the treatment of pneumonia and shipping fever complications associated with Pasteurella spp., and Hemophilus spp.; infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis; foot rot and diphtheria caused by Fusobacterium necrophorum; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresi; leptospirosis caused by Leptospira pomona; and wound infection and acute metritis caused by strains of staphylococci and streptococci organisms sensitive to oxytetracycline.
    Swine: indicated in the treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli; pneumonia caused by Pasteurella multocida; and leptospirosis caused by Leptospira pomona. In sows, it is indicated as an aid in the control of
    infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by
    Escherichia coli.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplement provides for changes to the product labeling to include lactating dairy cows. Also, a tolerance for oxytetracycline in milk is established at 0.3ppm.
  • Summary

    This supplement provides for changes to the product labeling to include a subcutaneous (SC) route of administration in cattle. Also, the indications section of the labeling will be revised to include "pre-ruminating (veal) calves."

  • Summary

    This supplement provides for the codification of a revised tolerance for residues of oxytetracycline in edible tissues.

  • EA 113-232
  • FONSI 113-232
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    Cattle: For the treatment of pneumonia and shipping fever complex.
    Swine: For the treatment of the bacterial enteritis.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    The supplement provides for use in lactating dairy cattle.
  • Summary
    Addition of subcutaneous route of administration for beef cattle, nonlactating dairy cattle, and preruminating (veal) calves.
  • Summary

    For use in the treatment of bacterial diseases in beef cattle, nonlactating dairy cattle and swine when caused by two oxytetracycline susceptible organisms.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    The supplement provides for the use in lactating diary cattle.
  • Summary
    The supplement provides for the addition of the subcutaneous administration of oxytetracycline injectable solution in beef cattle, non-lactating dairy cattle, and calves, including pre-ruminating (veal) calves.
  • Summary

    For use in the treatment of infectious diseases in beef cattle, nonlactating dairy cattle and swine when due to oxytetracycline susceptible organisms.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    OXYTETRACYCLINE HCL INJECTABLE SOLUTION is for treatment of:

    Pasteurella spp. -- Bacterial pneumonia and shipping fever complex associated with Pasteurella spp.

    Escherichia coli -- Bacterial enteritis (scours)

    Spherophorous necrophorus -- Necrotic pododermatitis (foot rot), calf diphtheria

    Actinobacillus lignierseii -- Wooden tongue

    Wound infection, acute metritis, traumatic injury -- caused by oxytetracycline susceptible strains of streptococcal and staphylococcal bacteria

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplemental application provides for the use in lactating cattle.
  • Summary
    This supplemental application establishes a 28 day withdrawal period for subcutaneous use in cattle and intramuscular use in swine (all approved routes of administration in cattle and swine).
  • Summary
    To add the subcutaneous route of administration to the label for cattle.
  • Summary
    OXY-TET 200/BIO-MYCIN 200 is intended for use in the treatment of the following diseases in beef cattle, nonlactating dairy cattle and swine when due to oxytetracycline susceptible organisms. CATTLE: OXY-TET 200 is indicated in the treatment of pneumonia and shipping fever complex associated with Pasteurella spp. and Hemophilus spp.; infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis ; foot rot and diphtheria caused by Fusobacterium necrophorum ; bacterial enteritis (scours) caused by Escherichia coli ; wooden tongue caused by Actinobacillus lignieresi ; leptospirosis caused by Leptospira pomona ; and wound infections and acute metritis caused by strains of staphylococci and streptococci organisms sensitive to oxytetracycline. SWINE: In swine, OXY-TET 200 is indicated in the treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli ; pneumonia caused by Pasteurella multocida ; and leptospirosis caused by Leptospira pomona . In sows, OXY-TET 200 is indicated as an aid in the control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    The use of OXYTET 10 Injection is indicated in beef cattle, beef calves, non-lactating dairy cattle and dairy calves for the treatment of the following disease conditions caused by one or more of the oxytetracycline sensitive pathogens listed as follows Bacterial Pneumonia and Shipping Fever Complex associated with Pasteurella spp.; Bacterial Enteritis (scours) caused by Escherichia coli; Necrotic Pododermatitis (Foot Rot) and Calf Diphtheria caused by Fusobacterium necrophorum; Wooden Tongue caused by Actinobacillus lignieresii; and Wound Infections, Acute Metritis and Traumatic Injury caused by susceptible strains of streptococcusand staphylococcus organisms.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplemental NADA provides for the subcutaneous route of administration and the application of new tolerances (61 FR 67435) to the approved product, Oxyject® 100
SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    This supplement provides for the addition of an indication for the control of mortality due to columnaris disease associated with Flavobacterium columnare in catfish and freshwater-reared salmonids.

  • Summary

    Freshwater-reared salmonids weighing up to 55 grams: For marking the skeletal tissue.

  • Summary

    This supplement provides for the addition of an indication for the control of mortality in freshwater-reared salmonids due to coldwater disease associated with Flavobacterium psychrophilum, the addition of an indication for the control of mortality in freshwater-reared Oncorhynchus mykiss due to columnaris associated with Flavobacterium columnare, removal of the limitation on treating salmonids in water temperatures below 9°C, and the addition to the label of the previously approved indication for marking of skeletal tissue in Pacific salmon.

  • Summary
    This supplement provides for the change of the active ingredient from the mono-alkyl (C8-C18) trimethylammonium oxytetracycline to the oxytetracycline dihydrate, the change of the oxytetracycline concentration from 100 g/lb to 200 g/lb, the change of the product name to reflect the change in the oxytetracycline concentration, and the addition of the approved lobster indication to the label for the control of gaffkemia caused by Aerococcus viridans.
  • EA 038-439
  • FONSI 038-439
  • EA 038-439
  • FONSI 038-439

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    FOR THE CONTROL AND TREATMENT OF THE FOLLOWING DISEASES IN SWINE – Bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis, and bacterial pneumonia caused by Pasteurella multocida susceptible to oxytetracycline. FOR BREEDING SWINE: Leptospirosis (reducing the incidence of abortions and shedding of leptospira) caused by Leptospira pomona, susceptible to oxytetracycline.

  • Summary
    • for control of Mycoplasma synoviae, M. gallisepticum, Escherichia coli, and Pasteurella multocida in chickens.
    • for control of Hexamita meleagridis, Mycoplasma synoviae, transmissible eneritis and coronaviral enteritis in turkeys.
    • for control and treatment of Escherichia coli, Salmonella choleraesuis, Pasteurella multiocida and Leptospira pomona in swine.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    Beef and non-lactating dairy cattle, calves, including pre-ruminating (veal) calves: for the treatment of pneumonia and shipping fever complex associated with Pasteurella spp. and Haemophilus spp.; infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis; foot-rot and diphtheria caused by Fusobacterium necrophorum; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresi; leptospirosis caused by Leptospira pomona; and wound infections and acute metritis caused by strains of staphylococcal and streptococcal organisms sensitive to oxytetracycline. Also, TETRADURE 300 is indicated (prescription use) for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia (Pasteurella) haemolytica. Swine: for the treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli; pneumonia caused by Pasteurella multocida; and leptospirosis caused by Leptospira pomona. In sows, oxytetracycline is indicated as an aid in the control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    Oxytetracycline HCl (50 mg and 100 mg) is intended for use in the treatment of the following diseases in beef cattle and non-lactating dairy cattle when due to oxytetracycline-susceptible organisms:

    Cattle: In cattle, Oxytetracycline (50 mg and 100 mg) is indicated in the treatment of pneumonia and shipping fever complex associated with Pasteurella spp. and Hemophilus spp.; foot-rot and diphtheria caused by Fusobacterium necrophorum; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresii; leptospirosis caused by Leptospira pomona; and wound infections and acute metritis caused by strains of staphylococci and streptococci organisms sensitive to oxytetracycline.

    If the product contains the statement "Federal law restricts this drug to use by or on the order of a licensed veterinarian," it may contain additional directions for use in beef cattle and non-lactating dairy cattle for the treatment of anaplasmosis caused by Anaplasma marginale and anthrax caused by Bacillus anthracis.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For the treatment of bacterial pneumonia associated with Pasteurella spp. and for the control of associated pyrexia in beef and non-lactating dairy cattle.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For increased rate of weight gain and improved feed efficiency; reduction of liver abscesses; for prevention and treatment of the early stages of shipping fever complex; the treatment of bacterial enteritis caused by Escherichia coli and bacterial pneumonia (shipping fever complex) caused by Pasteurella multocida susceptible to oxytetracycline.

  • Summary
    This supplement establishes a zero-day withdrawal period for swine administered oxytetracycline at 10 mg/lb/day for 14 days.
  • Summary

    This supplement establishes a zero-day withdrawal period for swine administered oxytetracycline at 10 mg/lb/day for 14 days.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For the treatment of bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis susceptible to oxytetracycline, treatment of bacterial pneumonia caused by Pasteurella multocida susceptible to oxytetracycline, and increased rate of weight gain and improved feed efficiency.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    To add a claim for the marking of skeletal marking of tissues of all finfish fry and fingerlings.
  • Summary
    This supplement provides for a revised withdrawal time of oxytetracycline hydrochloride soluble powder in the drinking water of turkeys and swine.
  • Summary

    This supplement provides for use of this product in swine.

  • EA 130-435
  • FONSI 130-435
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplement provides for a change in the proprietary name from Oxytetracycline HCl Soluble Powder to Tetroxy 25®, the removal of the residue warning statement for pre-ruminating and veal calves from the labeling and the addition of a new species (honey bees) and the corresponding indications. Tetroxy 25® is indicated for the control of American Foulbrood caused by Paenibacillus larvae and European Foulbrood caused by Streptococcus pluton susceptible to oxytetracycline.
  • Summary

    This supplemental application provides for the addition of the 2.26 kg (5 lb) bucket with a scoop. The scoop has also been added to the 907.2 g (2 lb) bucket. Revised labeling provides the statement warning against use in calves to be processed for veal and female dairy cattle 20 months of age or older.

  • Summary

    For control control and treatment of a variety of infectious diseases caused by bacteria susceptible to oxytetracycline in chickens turkeys swine, cattle, and sheep.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplemental applicaiton provides for the additional use in a new species, finfish fry and fingerlings, for skeletal marking by immersion as an aid in identification.
  • Summary

    OXYTETRACYCLINE HCL SOLUBLE POWDER – 343 is indicated for a variety of bacterial infections in cattle, sheep, swine, chickens, turkeys, and honeybees associated with organisms susceptible to oxytetracycline.  CALVES, BEEF CATTLE AND NON-LACTATING DAIRY CATTLE: Control and treatment of bacterial enteritis caused by Escherichia coli and bacterial pneumonia (shipping fever complex) caused by Pasteurella multocida.
    SHEEP: Control and treatment of bacterial enteritis caused by Escherichia coli and bacterial pneumonia (shipping fever complex) caused by Pasteurella multocida.
    SWINE: Control and treatment of bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis and bacterial pneumonia caused by Pasteurella multocida. For Breeding Swine: Leptospirosis (reducing the incidence of abortions and shedding of leptospira) caused by Leptospira pomona.
    CHICKENS: Control of infectious synovitis caused by Mycoplasma synoviae, chronic respiratory disease (CRD) and air sac infection caused by Mycoplasma gallisepticum and Escherichia coli, and fowl cholera caused by Pasteurella multocida.
    TURKEYS: Control of hexamitiasis caused by Hexamita meleagridis and infectious synovitis caused by Mycoplasma synoviae. Growing turkeys-complicating bacterial organisms associated with bluecomb (transmissible enteritis, coronaviral enteritis).
    HONEYBEES: Control and treatment of American and European foulbrood caused by Bacillus larvae.

  • Summary

    Chickens: For the control and treatment of infectious synovitis caused by Mycoplasma synoviae; chronic respiratory disease (CRD) and air sac infection caused by Mycoplasma gallisepticum and Escherichia coli; fowl cholera caused by Pasteurella multocidaTurkeys: For the control and treatment of hexamitiasis caused by Hexamita meleagridis; infectious synovitis caused by Mycoplasma synoviae; and control of complicating bacterial organisms associated with bluecomb (transmissible enteritis, coronaviral enteritis).
    Cattle: For the treatment and control in calves, beef cattle and nonlactating dairy cattle of bacterial enteritis caused by Escherichia coli and bacterial pneumonia (shipping fever complex) caused by Pasteurella multocida.
    Swine: For the control and treatment of bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis, bacterial pneumonia caused by Pasteurella multocida; and reducing the incidence of abortions and shedding of leptospira in breeding swine caused by Leptospira pomona.
    Sheep: For the treatment and control of bacterial enteritis caused by Escherichia coli and bacterial pneumonia (shipping fever complex) caused by Pasteurella multocida.



SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    As an aid in the reduction of mortality due to air sacculitis (air sac infection) caused by Escherichia coli sensitive to oxytetracycline and for the prevention of coccidiosis caused by Eimeria necatrix, E. tenella, E. acervulina, E. brunetti, E. mivati and E. maxima .
SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For the prevention of coccidiosis in broiler chickens caused by Eimeria tenella, E. necatrix, E. acervulina, E. maxima, E. brunetti , and E. mivati , and as an aid in the reduction of mortality due to airsacculitis (air sac infection) caused by Escherichia coli infections sensitive to oxytetracycline.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    To mark skeletal tissues, most often the otoliths, of all finfish fry and fingerlings for subsequent identification.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    The supplement provides for approval of an additional packet size, 9.87 oz [280 g], a different trade name, an alternate concentration of active ingredient and a change in the inactive ingredients in the finished dosage form.
  • Summary
    Revised withdrawal period for turkeys and swine.Under the provisions of the Federal Food, Drug, and Cosmetic Act, as amended by the Generic Animal Drug and Patent Term Restoration Act, (53 FR 50460, December 15, 1988, First GADPTRA Policy Letter) an abbreviated new animal drug application (ANADA) may be submitted for a generic version of an approved new animal drug (pioneer product). New target animal safety data, drug effectiveness data, and human food safety data (other than tissue residue data) are not required for approval of an ANADA. An ANADA relies on the target animal safety, drug effectiveness, and human food safety data in the pioneer's new animal drug application. Ordinarily, the ANADA sponsor shows that the generic product is bioequivalent to the pioneer. If bioequivalence is demonstrated through a clinical end-point study, then a tissue residue study to establish the withdrawal time for the generic product is also required. For certain dosage forms, the agency will grant a waiver from conducting an in vivo bioequivalence study (55 FR 24645, June 18, 1990; Fifth GADPTRA Policy Letter; Bioequivalence Guideline, April 1990).Based upon the formulation characteristics of the genetic product, Agri Laboratories Ltd. was granted a waiver from conducting an in vivo bioequivalence study for Oxytetracycline HCl Soluble Powder. The genetic and pioneer products contain the same active ingredient and are water soluble powders administered as oral solutions. The genetic product contains no inactive ingredients that may significantly affect the absorption of the active ingredient.
  • Summary

    CHICKENS

    Control of infectious synovitis caused by Mycoplasma synoviae

    Control of chronic respiratory disease (CRD) and air sac infection caused by Mycoplasma gallisepticum and Escherichia coli

    Control of fowl cholera caused by Pasteurella multocida

    TURKEYS

    Control of Hexamitiasis caused by Hexamita meleagridis

    Control of infectious synovitis caused by Mycoplasma synoviae

    Growing turkeys: Control of body weight complicating bacterial organisms associated with bluecomb (transmissible enteritis, coronaviral enteritis)

    SWINE

    FOR THE CONTROL AND TREATMENT OF THE FOLLOWING DISEASES IN SWINE:

    Bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis, susceptible to oxytetracycline. Bacterial pneumonia caused by Pasteurella multocida, susceptible to oxytetracycline.

    FOR BREEDING SWINE: Leptospirosis (reducing the incidence of abortions and shedding of leptospira) caused by Leptospira pomona, susceptible to oxytetracycline.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    The effectiveness oxytetracycline HCl soluble powder was reviewed by the National Academy of Sciences/National Research Council Drug Efficacy Study Implementation (NAS/NRC DESI) and has been deemed effective when labeled as specified in the Indications and Recommended Dosage section of the summary.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplement provides for the addition of new species (finfish and honey bees) and their corresponding indications to all labeling components.
  • Summary
    Revised withdrawal period (0-day) in swine
  • Summary
    Revised withdrawal period (0-day) in turkeys & additional package size of 23.9 oz..
  • Summary
    Control of certain diseases caused by bacteria susceptible to oxytetracycline hydrochloride.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    The supplement provides for the addition of the subcutaneous administration of oxytetracycline injectable solution in cattle and for the use in lactating dairy cattle.
  • Summary
    Cattle: For the treatment of pneumonia and shipping fever complex associated with Pasteurella spp. and Hemophilus spp.; infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis; foot rot and diphtheria caused by Fusobacterium necrophorum; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresii; leptospirosis caused by Leptospira pomona; and wound infection and acute metritis caused by strains of staphylococci and streptococci organisms sensitive to oxytetracycline. Swine: For the treatment of the bacterial enteritis (scours, colibacillosis) caused by Escherichia coli; pneumonia caused by Pasteurella multocida; and leptospirosis caused by Leptospira pomona. In sows as an aid in the control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For the treatment of bacterial diseases in chickens, turkeys, and swine.

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Usage

It is used in dogs for the treatment of bacterial pneumonia caused by Brucella bronchiseptica, tonsillitis caused by Streptococcus hemolyticus, bacterial enteritis caused by Escherichia coli, urinary tract infections caused by Escherichia coli, and wound infections caused by Staphylococcus aureus. The drug can be used for continuation of compatible antibiotic therapy following parenteral oxytetracycline administration where rapidly attained, sustained antibiotic blood levels are required. The duration of treatment required to obtain favorable response will depend to some extent on the severity and degree of involvement and the susceptibility of the infectious agent. Clinical response to antibiotic therapy usually occurs within 48 to 72 hours. If improvement is not observed within that period, the diagnosis and course of treatment should be reconsidered. To assure adequate treatment, administration of the drug should continue for at least 48 hours following favorable clinical response. It is used in cats for the treatment of bacterial pneumonia caused by Brucella bronchiseptica, tonsillitis caused by Streptococcus hemolyticus, bacterial enteritis caused by Escherichia coli, urinary tract infections caused by Escherichia coli, and wound infections caused by Staphylococcus aureus. The drug can be used for continuation of compatible antibiotic therapy following parenteral oxytetracycline administration where rapidly attained, sustained antibiotic blood levels are required. The duration of treatment required to obtain favorable response will depend to some extent on the severity and degree of involvement and the susceptibility of the infectious agent. Clinical response to antibiotic therapy usually occurs within 48 to 72 hours. If improvement is not observed within that period, the diagnosis and course of treatment should be reconsidered. To assure adequate treatment, administration of the drug should continue for at least 48 hours following favorable clinical response. Control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline.

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Prepare a fresh solution daily. Administer 7 to 14 days. Not to be used for more than 14 consecutive days. Use as sole source of drinking water. Do not use in birds producing eggs for human consumption. Prepare a fresh solution daily. Administer up to 14 days. Do not use for more than 14 consecutive days. Use as a sole source of oxytetracycline. Zero-day slaughter withdrawal in swine.

Side Effects

No approved side-effect narrative is linked yet.

openFDA reaction signals are available for Dog 8 and Cat 8 (view top reported reactions).

Top Reported Reactions (openFDA)

Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).

Dog
Skin & allergy
Hives (1)
Behavior
Behavioral disorder (unspecified) (1)
Other
Anal sac disorder (1) Corneal ulcer (1) Injection site pain (1) Leucocytosis NOS (1) Licking (1) Nasal discharge (1)
Cat
Digestive
Loss of appetite (3)
Neurologic
Unsteady walking (ataxia) (2)
Behavior
Behavioral disorder (unspecified) (2)
Other
Death by euthanasia (3) Abnormal pupil light reflex (2) Dilated pupils (2) Ear infection NOS (2) Head shake - ear disorder (2)

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Cat, Domestic Shorthair, Male, 8 year, 5.44 kilogram • Drug: MSK, Unknown • Reactions: Behavioral disorder (unspecified), Tiredness (lethargy), Vomiting, Decreased appetite, Death by euthanasia • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2024-US-070360
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 8.00 Year
  • Weight: 5.440 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Behavioral disorder (unspecified) Tiredness (lethargy) Vomiting Decreased appetite Death by euthanasia
Outcomes: Euthanized

Cat, Siamese, Female, 1 year, 3.26 kilogram • Drug: MSK, Unknown • Reactions: Behavioral disorder (unspecified), Unsteady walking (ataxia), Weight loss, Walking difficulty, Third eyelid extrusion • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2024-US-043413
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 1.00 Year
  • Weight: 3.260 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Behavioral disorder (unspecified) Unsteady walking (ataxia) Weight loss Walking difficulty Third eyelid extrusion
Outcomes: Ongoing

Cat, Domestic Shorthair, Unknown, 10.5 year, 5.3 kilogram • Drug: MSK, Unknown • Reactions: Not urinating, Urinary bladder disorder NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2024-US-041896
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Unknown
  • Age: 10.50 Year
  • Weight: 5.300 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Not urinating Urinary bladder disorder NOS
Outcomes: Outcome Unknown

Cat, Cat (other), Female, 11 year, 3.62 kilogram • Drug: MSK, Unknown • Reactions: Constipation, Decreased bowel movements, Death by euthanasia • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2024-US-004991
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 11.00 Year
  • Weight: 3.620 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Constipation Decreased bowel movements Death by euthanasia
Outcomes: Euthanized

Dog, Schnauzer - Miniature, Female, 9 month, 6.07 kilogram • Drug: MSK, Parenteral • Reactions: Leucocytosis NOS, Neutrophilia, Injection site pain, Shaking, Licking… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2023-US-040406
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 9.00 Month
  • Weight: 6.070 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Parenteral
Reactions Reported:
Leucocytosis NOS Neutrophilia Injection site pain Shaking Licking Anal sac disorder Behavioral disorder (unspecified)
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Male, 2 year, 6.9 kilogram • Drug: MSK, Ointment, Unknown • Reactions: Dilated pupils, Abnormal pupil light reflex, Unsteady gait, Head shake - ear disorder, Head tilt - neurological disorder… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2023-US-021175
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 2.00 Year
  • Weight: 6.900 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Ointment
Reactions Reported:
Dilated pupils Abnormal pupil light reflex Unsteady gait Head shake - ear disorder Head tilt - neurological disorder Ear infection NOS
Outcomes: Ongoing

Dog, Chihuahua, Male, 14 year, 4.649 kilogram • Drug: MSK, Unknown • Reactions: Partial deafness, Nasal discharge • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2020-US-027496
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 14.00 Year
  • Weight: 4.649 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Partial deafness Nasal discharge
Outcomes: Outcome Unknown

Dog, Bulldog, Male, 39.009 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Corneal ulcer, Hives, Skin inflammation NOS • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2016-US-013744
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Weight: 39.009 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Corneal ulcer Hives Skin inflammation NOS
Outcomes: Recovered/Normal

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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