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Meds A-Z

Clindamycin

Detailed information about Clindamycin

Official label facts Owner quick guide first Marketing clearly labeled
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Pet Owner Quick Guide

Start here: what this medicine is for, what it does, and when it's usually needed.

Usually used for:

For the treatment of skin infections (wounds and abscesses) due to susceptible strains of coagulase-positive staphylococci ( Staphylococcus aureus or S. intermedius ), deep wounds and abscesses due to susceptible strains...

What it does:

For the treatment of skin infections (wounds and abscesses) due to susceptible strains of coagulase-positive staphylococci ( Staphylococcus aureus or S. intermedius ), deep wounds and abscesses due to susceptible strains...

When it's needed:

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Federal law restricts this drug to use by or on the order of a licensed veterinarian

Call your vet sooner if you notice:

  • Federal law restricts this drug to use by or on the order of a licensed veterinarian. Federal law restricts this drug to use by or on the order of a licensed veterinarian

Commonly reported reactions:

  • (2 reports)
  • (1 reports)
  • (1 reports)

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
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Clindamycin

Clindamycin

Drug type: Generic ingredient • Branded profile FDA branded products available

Species: Both

Manufacturer: MSK

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: MSK
Form: Capsule, Liquid, Liquid (Solution), Tablet
Identifiers:
ANADA: 200193 ANADA: 200291 ANADA: 200298 ANADA: 200316 ANADA: 200383 ANADA: 200398 ANADA: 200538 ANADA: 200813 NADA: 120161 NADA: 135940 NDC Package: 13985-957-25 NDC Package: 51311-400-40 NDC Package: 51311-402-75 NDC Package: 51311-404-15 NDC Package: 54771-3043-1 NDC Package: 54771-3044-1 NDC Package: 54771-3045-1 NDC Package: 54771-3179-1 NDC Package: 54771-3179-2 NDC Package: 69043-013-20
Source metadata:

Warnings / Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Federal law restricts this drug to use by or on the order of a licensed veterinarian

  • High: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Federal law restricts this drug to use by or on the order of a licensed veterinarian
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
29
Species represented
2
Most Reported Reactions
Reaction Cases Species Serious cases
2 Cat, Dog 2
1 Cat 1
1 Cat 1
1 Cat 1
1 Cat 1
1 Dog 1
1 Dog 1
1 Dog 1

Species coverage: Dog (21) Cat (11)

View detailed reaction table
Reaction Species Seriousness Frequency Reports
Dog Serious - 1
Cat Non-serious - 1
Cat Non-serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Non-serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Source metadata:

Storage & Handling

No storage/handling guidance is linked yet.

Source metadata: No source yet.

Documents

Official label facts are separated from secondary summaries.

Official documents: 25 • Secondary summaries: 0

Secondary summaries

No source yet.

Promotional Materials (Marketing)

This content is marketing material and not clinical guidance.

No marketing assets are linked yet.

No source yet.

Source metadata: No source yet.
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Technical appendix (vet reference)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 16, 2026, 11:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:22 AM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: Antirobe Aquadrops® Antirobe® Capsules ClindaMed™ Oral Drops ClindaRobe™ Clindamycin Hydrochloride Capsules Clindamycin Hydrochloride Oral Drops Clindamycin Hydrochloride Oral Liquid Clindamycin Hydrochloride Tablets Clinsol® Clintabs®
Case-reported brands (openFDA): MSK
Catalog species: Both FDA-labeled species: Cat, Dog
Rx/OTC: RX
Form/route: Capsule, Liquid, Liquid (Solution), Tablet Oral
Applications: ANADA 200-813 • NADA 120-161 • ANADA 200-538 • ANADA 200-398 • NADA 135-940 • ANADA 200-193 • ANADA 200-298 • ANADA 200-383 • ANADA 200-291 • ANADA 200-316
NDC: Packages 58829-309-20 Products 58829
Documents: 15 (FOI: 15) • SPL: 10 Label highlights Official documents
Safety (openFDA)
Top reactions: Dog 56 Cat 56 View
Case summaries: 10 (showing 8) View
openFDA reports are unverified and do not prove causation.

Explore
Linked using: Fda_Label (0.95), Fda_Label (0.95)

Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Federal law restricts this drug to use by or on the order of a licensed veterinarian. Federal law restricts this drug to use by or on the order of a licensed veterinarian (Contraindication, High)
Top reaction signals
Abnormal menace reflex test (1) Application site excoriation (1) Application site hair loss (1) Collapse NOS (see also Cardio-vascular and Neurological disorders) (1) Death (1) Dilated pupils (1) Drooling (1) Elevated alanine aminotransferase (ALT) (1) Elevated globulins (1) Elevated serum alkaline phosphatase (ALP) (1) Elevated total bilirubin (1) Emesis (multiple) (1) Facial paralysis (1) Fever (1) Head tilt - neurological disorder (see also Head tilt - ear disorder) (1) Hiding (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
ANADA: 200193 ANADA: 200291 ANADA: 200298 ANADA: 200316 ANADA: 200383 ANADA: 200398 ANADA: 200538 ANADA: 200813 NADA: 120161 NADA: 135940 NDC Package: 13985-957-25 NDC Package: 51311-400-40 NDC Package: 51311-402-75 NDC Package: 51311-404-15 NDC Package: 54771-3043-1 NDC Package: 54771-3044-1 NDC Package: 54771-3045-1 NDC Package: 54771-3179-1 NDC Package: 54771-3179-2 NDC Package: 69043-013-20 NDC Package: 69043-014-20 NDC Package: 69043-015-01 NDC Package: 69043-015-05 NDC Package: 69043-016-01
Package NDC Product NDC Form / Route Status
13985-957-25 13985 -
51311-400-40 51311 -
51311-402-75 51311 -
51311-404-15 51311 -
54771-3043-1 54771 -
54771-3044-1 54771 -
54771-3045-1 54771 -
54771-3179-1 54771 -
54771-3179-2 54771 -
69043-013-20 69043 -
69043-014-20 69043 -
69043-015-01 69043 -
69043-015-05 69043 -
69043-016-01 69043 -
86101-052-18 86101 -
86101-053-15 86101 -
86101-054-11 86101 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

  • FOI Summary oA 200-813 Approved June 27, 2025.pdf • FOI summary • Official • July 1, 2025
    FDA FOI summary for application 200813
  • ucm069817.pdf • FOI summary • Official • Dec. 10, 2019
    FDA FOI summary for application 120161
  • UCM355629.pdf • FOI summary • Official • Oct. 2, 2018
    FDA FOI summary for application 200538
  • ucm061348.pdf • FOI summary • Official • Dec. 27, 2017
    FDA FOI summary for application 200398
  • N135940_Supp_11_16_89(2).pdf • FOI summary • Official • July 11, 2017
    FDA FOI summary for application 135940
  • UCM454278.pdf • FOI summary • Official • July 11, 2017
    FDA FOI summary for application 135940
  • ucm069874.pdf • FOI summary • Official • July 11, 2017
    FDA FOI summary for application 135940
  • A200193_Org_8_1_1997.pdf • FOI summary • Official • May 22, 2017
    FDA FOI summary for application 200193
  • UCM061609.pdf • FOI summary • Official • May 22, 2017
    FDA FOI summary for application 200193
  • UCM061610.pdf • FOI summary • Official • May 22, 2017
    FDA FOI summary for application 200193
  • ucm061338.pdf • FOI summary • Official • June 1, 2016
    FDA FOI summary for application 200383
  • ucm061770.pdf • FOI summary • Official • June 1, 2016
    FDA FOI summary for application 200316
  • ucm061742.pdf • FOI summary • Official • June 1, 2016
    FDA FOI summary for application 200298
  • ucm061743.pdf • FOI summary • Official • June 1, 2016
    FDA FOI summary for application 200298
  • ucm061719.pdf • FOI summary • Official • June 1, 2016
    FDA FOI summary for application 200291

Data Sources & Revision History

Every non-trivial field is expected to include provenance and update timestamps.

Official 18 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Federal law restricts this drug to use by or on the order of a licensed v… (Official, 2026-02-12)
  • side_effects: Top reported reactions (openFDA): Vomiting, Death by euthanasia, Lethargy (see also Central nervous system depression in 'Neurological'), Anorexia, Other abnor… (Official, 2026-02-12)
  • usage: For the treatment of skin infections (wounds and abscesses) due to susceptible strains of coagulase-positive staphylococci ( Staphylococcus aureus or S. interm… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Clindamycin Hydrochloride Tablets
RX
Clindamycin Hydrochloride
Tablet Oral
Felix Pharmaceuticals Pvt. Ltd. ANADA 200-813 Approved Jul 1, 2025
Antirobe® Capsules
RX
Clindamycin Hydrochloride
Capsule Oral
Zoetis Inc. NADA 120-161 Approved Dec 10, 2019
ClindaMed™ Oral Drops
RX
Clindamycin
Liquid Oral
Bimeda Animal Health Limited ANADA 200-538 Approved Oct 2, 2018
Clindamycin Hydrochloride Oral Drops
RX
Clindamycin Hydrochloride
Liquid (Solution) Oral
First Priority, Inc. ANADA 200-398 Approved Dec 27, 2017
Antirobe Aquadrops®
RX
Clindamycin Hydrochloride
Liquid (Solution) Oral
Zoetis Inc. NADA 135-940 Approved Jul 11, 2017
Clindamycin Hydrochloride Oral Liquid
RX
Clindamycin Hydrochloride
Liquid (Solution) Oral
Cronus Pharma Specialities India Private Ltd. ANADA 200-193 Approved May 22, 2017
Clindamycin Hydrochloride Capsules
RX
Clindamycin Hydrochloride
Capsule Oral
Cronus Pharma Specialities India Private Ltd. ANADA 200-298 Approved Jun 1, 2016
ClindaRobe™
RX
Clindamycin Hydrochloride
Capsule Oral
Teva Canada Ltd. ANADA 200-383 W Jun 1, 2016
Clinsol®
RX
Clindamycin Hydrochloride
Liquid (Solution) Oral
Virbac AH, Inc. ANADA 200-291 Approved Jun 1, 2016
Clintabs®
RX
Clindamycin Hydrochloride
Tablet Oral
Virbac AH, Inc. ANADA 200-316 Approved Jun 1, 2016

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Composition / specifications
25 mg, 75 mg, and 150 mg
Dogs
Indication

For the treatment of skin infections (wounds and abscesses) due to susceptible strains of coagulase-positive staphylococci (Staphylococcus aureus or S. intermedius), deep wounds and abscesses due to susceptible strains of Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum, and Clostridium perfringens, dental infections due to susceptible strains of S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens, and osteomyelitis due to susceptible strains of S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens.

Dosage

Wounds, abscesses, and dental infections: 2.5 to 15 mg per pound (/lb) body weight every 12 hours for a maximum of 28 days. Osteomyelitis: 5.0 to 15 mg/lb body weight every 12 hours for a minimum of 28 days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
Each capsule contains the equivalent of 25, 75, 150 or 300 milligrams of clindamycin as the hydrated hydrochloride salt.
Dogs
Indication

For the treatment of skin infections (wounds and abscesses) due to susceptible strains of coagulase-positive staphylococci (Staphylococcus aureus or S. intermedius), deep wounds and abscesses due to susceptible strains of Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum, and Clostridium perfringens, dental infections due to susceptible strains of S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens, and osteomyelitis due to susceptible strains of S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens.

Dosage

Wounds, abscesses, and dental infections: 2.5 to 15 milligrams per pound of body weight every 12 hours for a maximum of 28 days. Osteomyelitis: 5.0 to 15 milligrams per pound of body weight every 12 hours for a minimum of 28 days.

Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied • Cat, No Use Class Stated Or Implied
Composition / specifications
Each mL contains clindamycin hydrochloride equivalent to 25 mg clindamycin.
<strong>Dogs</strong>
Indication
For the treatment of infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below:

Skin infections (wounds and abscesses) due to coagulase positive staphylococci (Staphylococcus aureus or Staphylococcus intermedius). Deep wounds and abscesses due to Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens.

Dental infections due to Staphylococcus aureus, Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens.

Osteomyelitis due to Staphylococcus aureus, Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens.

Dosage
Wounds, abscesses, and dental infections: 2.5 to 15 mg per pound body weight every 12 hours for a maximum of 28 days.

Osteomyelitis: 5.0 to 15 mg/lb body weight every 12 hours for a minimum of 28 days.

Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian
<strong>Cats</strong>
Indication
Skin infections (wounds and abscesses) due to Staphylococcus aureus, Staphylococcus intermedius, Streptococcus spp. Deep wounds and abscesses due to Clostridium perfringens and Bacteroides fragilis.

Dental infections due to Staphylococcus aureus, Staphylococcus intermedius, Streptococcus spp., Clostridium perfringens and Bacteroides fragilis.

Dosage
5.0 to 15.0 mg/lb body weight every 24 hours for a maximum of 14 days
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied • Cat, No Use Class Stated Or Implied
Composition / specifications
Each milliliter of solution contains the equivalent of 25 milligrams (mg) clindamycin as the hydrochloride salt.
Dogs
Indication
For the treatment of skin infections (wounds and abscesses) due to susceptible strains of coagulase-positive staphylococci (Staphylococcus aureus or S. intermedius), deep wounds and abscesses due to susceptible strains of Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium ecrophorum, and Clostridium perfringens, dental infections due to susceptible strains of S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens, and osteomyelitis due to susceptible strains of S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens
Dosage
Wounds, abscesses, and dental infections: 2.5 to 15 milligrams per pound of body weight every 12 hours for a maximum of 28 days. Osteomyelitis: 5.0 to 15 milligrams per pound of body weight every 12 hours for a minimum of 28 days
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Cats
Indication
For the treatment of skin infections (wounds and abscesses) due to susceptible strains of S. aureus, S. intermedius, Streptococcus species, deep wounds and abscesses due to susceptible strains of Clostridium perfringens and Bacteroides fragilis, and dental infections due to susceptible strains of S. aureus, S. intermedius, Streptococcus species, C. perfringens, and B. fragilis
Dosage
5.0 to 15.0 milligrams per pound of body weight every 24 hours for a maximum of 14 days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied • Cat, No Use Class Stated Or Implied
Composition / specifications
Each milliliter of solution contains the equivalent of 25 milligrams (mg) clindamycin as the hydrochloride salt.
Dogs
Indication

For the treatment of skin infections (wounds and abscesses) due to susceptible strains of coagulase-positive staphylococci (Staphylococcus aureus or S. intermedius), deep wounds and abscesses due to susceptible strains of Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum, and Clostridium perfringens, dental infections due to susceptible strains of S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens, and osteomyelitis due to susceptible strains of S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens.

Dosage
Wounds, abscesses, and dental infections: 2.5 to 15 milligrams per pound of body weight every 12 hours for a maximum of 28 days. Osteomyelitis: 5.0 to 15 milligrams per pound of body weight every 12 hours for a minimum of 28 days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Cats
Indication

For the treatment of skin infections (wounds and abscesses) due to susceptible strains of S. aureus, S. intermedius, Streptococcus species, deep wounds and abscesses due to susceptible strains of Clostridium perfringens and Bacteroides fragilis, and dental infections due to susceptible strains of S. aureus, S. intermedius, Streptococcus species, C. perfringens, and B. fragilis.

Dosage
5.0 to 15.0 milligrams per pound of body weight every 24 hours for a maximum of 14 days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied • Cat, No Use Class Stated Or Implied
Composition / specifications
Each milliliter of 8.64 percent alcoholic solution contains the equivalent of 25 milligrams of clindamycin (as the hydrochloride).
Cats
Indication
Aerobic bacteria: Treatment of soft tissue infections (wounds and abscesses) and dental infections caused by or associated with susceptible strains of Staphylococcus aureus, S. intermedius, and Streptococcus species Anaerobic bacteria: Treatment of soft tissue infections (deep wounds and abscesses) and dental infections caused by or associated with susceptible strains of Clostridium perfringens and Bacteroides fragilis.
Dosage
5.0 to 10.0 milligrams per pound of body weight every 24 hours for a maximum of 14 days (11 to 22 milligrams per kilogram of body weight per day).
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Dogs
Indication
For treatment of osteomyelitis caused by susceptible strains of Staphylococcus aureus, and osteomyelitis caused by or associated with susceptible strains of Bacteroides fragilis, Bacteroides melaninogenicus, Fusobacterium necrophorum, and Clostridium perfringens.
Dosage
Osteomyelitis: 5.0 milligrams per pound of body weight every 12 hours for a minimum of 28 days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Indication
For use in dogs for treatment of soft tissue infections (wounds and abscesses) and dental infections caused by susceptible strains of Staphylococcus aureus and for soft tissue infections (deep wounds and abscesses) and dental infections caused by or associated with susceptible strains of Bacteroides fragilis, Bacteroides melaninogenicus, Fusobacterium necrophorum, and Clostridium perfringens.
Dosage
Wounds abscesses, and dental infections: 2.5 milligrams per pound of body weight every 12 hours for a maximum of 28 days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
Each capsule contains the equivalent of 25, 75, or 150 milligrams of clindamycin as the hydrated hydrochloride salt.
Dogs
Indication
For the treatment of skin infections (wounds and abscesses) due to susceptible strains of coagulase-positive staphylococci (Staphylococcus aureus or S. intermedius), deep wounds and abscesses due to susceptible strains of Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum, and Clostridium perfringens, dental infections due to susceptible strains of S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens, and osteomyelitis due to susceptible strains of S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens.
Dosage
Wounds, abscesses, and dental infections: 2.5 milligrams per pound of body weight every 12 hours for a maximum of 28 days. Osteomyelitis: 5.0 milligrams per pound of body weight every 12 hours for a minimum of 28 days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
<span style="font-size: 10.5pt; font-family: Verdana; mso-fareast-font-family: 'Times New Roman'; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA; mso-bidi-font-family: 'Times New Roman'">Each capsule contains the equivalent of 25, 75, or 150 mg of clindamycin.</span>
Dogs
Indication
For the treatment of skin infections (wounds and abscesses) due to susceptible strains of coagulase-positive staphylococci (Staphylococcus aureus or S. intermedius), deep wounds and abscesses due to susceptible strains of Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum, and Clostridium perfringens, dental infections due to susceptible strains of S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens, and osteomyelitis due to susceptible strains of S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens.
Dosage
Wounds, abscesses, and dental infections: 2.5 to 15 milligrams per pound of body weight every 12 hours for a maximum of 28 days. Osteomyelitis: 5.0 to 15 milligrams per pound of body weight every 12 hours for a minimum of 28 days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied • Cat, No Use Class Stated Or Implied
Composition / specifications
Each milliliter of solution contains the equivalent of 25 milligrams (mg) clindamycin as the hydrochloride salt.
Dogs
Indication
For the treatment of skin infections (wounds and abscesses) due to susceptible strains of coagulase-positive staphylococci (Staphylococcus aureus or (S. intermedius), deep wounds and abscesses due to susceptible strains of (Bacteroides fragilis, (Prevotella melaninogenicus, (Fusobacterium necrophorum, and (Clostridium perfringens; dental infections due to susceptible strains of (S. aureus, (B. fragilis, (P. melaninogenicus, (F. necrophorum, and (C. perfringens; and osteomyelitis due to susceptible strains of (S. aureus, (B. fragilis, (P. melaninogenicus, (F. necrophorum, and (C. perfringens.
Dosage
Wounds, abscesses, and dental infections: 2.5 to 15 milligrams per pound of body weight every 12 hours for a maximum of 28 days. Osteomyelitis: 5.0 to 15 milligrams per pound of body weight every 12 hours for a minimum of 28 days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Cats
Indication
For the treatment of skin infections (wounds and abscesses) due to susceptible strains of Staphylococcus aureus, S. intermedius, Streptococcus spp.; deep wounds and abscesses due to susceptible strains of Clostridium perfringens and Bacteroides fragilis; and dental infections due to susceptible strains of S. aureus, S. intermedius, Streptococcus spp., C. perfringens, and B. fragilis.
Dosage
5.0 to 15.0 milligrams per pound of body weight every 24 hours for a maximum of 14 days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
Each tablet contains the equivalent of 25, 75 or 150 milligrams of clindamycin as the hydrochloride salt.
Dogs
Indication
For the treatment of skin infections (wounds and abscesses) due to susceptible strains of coagulase-positive staphylococci (Staphylococcus aureus or S. intermedius), deep wounds and abscesses due to susceptible strains of Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum, and Clostridium perfringens, dental infections due to susceptible strains of S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens, and osteomyelitis due to susceptible strains of S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens.
Dosage
Wounds, abscesses, and dental infections: 2.5 to 15 milligrams per pound of body weight every 12 hours for a maximum of 28 days. Osteomyelitis: 5.0 to 15 milligrams per pound of body weight every 12 hours for a minimum of 28 days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Official Documents (FDA)

Direct links to FDA-hosted PDFs and SPL packages (when available).

Documents
  • Summary

    For the treatment of skin infections (wounds and abscesses) due to susceptible strains of coagulase-positive staphylococci (Staphylococcus aureus or S. intermedius), deep wounds and abscesses due to susceptible strains of Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum, and Clostridium perfringens, dental infections due to susceptible strains of S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens, and osteomyelitis due to susceptible strains of S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    The supplement provides for the use of clindamycin hydrochloride (ANTIROBE Capsules) in dogs at a dose range of 2.5-15 mg/lb body weight every 12 hours for skin infections (wounds and abscesses), deep wounds and abscesses, and dental infections. It also provides for a dose range in dogs of 5-15 mg/lb every 12 hours for osteomyelitis. In addition, this supplement provides for the addition of a 300 mg capsule. This supplement also provides for the addition of recent MIC data derived from U.S. diagnostic laboratories.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For the treatment of infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below:
    Dogs: Skin infections (wounds and abscesses) due to coagulase positive staphylococci (Staphylococcus aureus or Staphylococcus intermedius). Deep wounds and abscesses due to Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens.
    Dental infections due to Staphylococcus aureus, Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens.
    Osteomyelitis due to Staphylococcus aureus, Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens.

    Cats: Skin infections (wounds and abscesses) due to Staphylococcus aureus, Staphylococcus intermedius, Streptococcus spp. Deep wounds and abscesses due to Clostridium perfringens and Bacteroides fragilis.
    Dental infections due to Staphylococcus aureus, Staphylococcus intermedius, Streptococcus spp., Clostridium perfringens and Bacteroides fragilis.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    Clindamycin Hydrochloride Oral Drops (for use in dogs and cats) is indicated for the treatment of infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below:
    Dogs: Skin infections (wounds and abscesses) due to coagulase positive staphylococci (Staphylococcus aureus or Staphyloccus intermedius). Deep wounds and abscesses due
    to Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum, and Clostridium perfringens. Dental infections due to S. auerus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens. Osteomyelitis due to S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens.
    Cats: Skin infections (wounds and abscesses) due to Staphylococcus aureus, Staphylococcus intermedius and Streptococcus spp. Deep wounds and infections due to Clostridium perfringens and Bacteroides fragilis. Dental infections due to S. aureus, S. intermedius, Streptococcus spp., C. perfringens, and B. fragilis.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    The supplement provides for the use of clindamycin hydrochloride (ANTIROBE AQUADROPS Liquid) in dogs at a dose range of 2.5-15 mg/lb body weight every 12 hours for skin infections (wounds and abscesses), deep wounds and abscesses, and dental infections. It also provides for a dose range in dogs of 5-15 mg/lb every 12 hours for osteomyelitis. In addition, this supplement provides for an expanded dose range of 5-15 mg/lb every 24 hours in cats. This supplement also provides for the addition of recent MIC data derived from a survey of U.S. diagnostic laboratories.
  • Summary
    This supplement provides for the use of clindamycin HCl (ANTIROBE AQUADROPS Liquid) in cats for new indications.
  • Summary

    This supplemental application provides for the following additional claims: Aerobic bacteria: for the treatment of dental infections caused by susceptible strains of Staphylococcus aureus. Anaerobic bacteria: for the treatment of soft tissue infections (deep wounds and abscesses), dental infections, and osteomyelitis caused by or associated with susceptible strains of Bacteroides fragilis, Bacteroides melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    The supplement provides for approval of a dose range and revised indications for use of Clindamycin Hydrochloride Oral Liquid in dogs and cats which was approved for the pioneer product under NADA 135-940 (67 FR 54954, Aug. 27, 2002) with no exclusivity period. The expanded range was changed from a point dose of 2.5 mg/lb. in dogs to an expanded range of 2.5 to 15 mg/lb. The change in cats was from a range of 5.0 to 10.0 mg/lb. to a range of 5.0 to 15.0 mg/lb. The revised indications provides for a change in the words ‘soft tissues infections’ to ‘skin infections’ for dogs and cats.
  • Summary
    provides for the addition of feline claims to the previous approved label for use in canine only.
  • Summary

    For therapy of wounds, abscesses, dental infections, and osteomyelitis.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For the treatment of infections caused by susceptible strains of the designated microorganisms in the specific conditions listed: Skin infections (wounds and abscesses) due to coagulase positive staphylococci (Staphylococcus aureus or S. intermedius), deep wounds and abscesses due to Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum, and Clostridium perfringens, dental infections due to S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens.
  • Summary
    For the treatment of infections caused by susceptible strains of the designated microorganisms in the specific conditions listed in the approval.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    CLINDAROBE Capsules is indicated for the treatment of infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below:
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For the treatment of infections caused by susceptible strains of the designated microorganism in the specific conditions listed for Dogs and Cats.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For treatment of infections caused by susceptible strains of the designated microorganisms in the specific conditions listed in the approval
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Usage

For the treatment of skin infections (wounds and abscesses) due to susceptible strains of coagulase-positive staphylococci ( Staphylococcus aureus or S. intermedius ), deep wounds and abscesses due to susceptible strains of Bacteroides fragilis , Prevotella melaninogenicus , Fusobacterium necrophorum , and Clostridium perfringens , dental infections due to susceptible strains of S. aureus , B. fragilis , P. melaninogenicus , F. necrophorum , and C. perfringens , and osteomyelitis due to susceptible strains of S. aureus , B. fragilis , P. melaninogenicus , F. necrophorum , and C. perfringens . For the treatment of skin infections (wounds and abscesses) due to susceptible strains of coagulase-positive staphylococci ( Staphylococcus aureus or S. intermedius ), deep wounds and abscesses due to susceptible strains of Bacteroides fragilis , Prevotella melaninogenicus, Fusobacterium necrophorum , and Clostridium perfringens , dental infections due to susceptible strains of S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum, and C. perfringens , and osteomyelitis due to susceptible strains of S. aureus, B. fragilis, P. melaninogenicus, F. necrophorum , and C. perfringens . For the treatment of skin infections (wounds and abscesses) due to susceptible strains of S. aureus, S. intermedius, Streptococcus species, deep wounds and abscesses due to susceptible strains of Clostridium perfringens and Bacteroides fragilis , and dental infections due to susceptible strains of S. aureus, S. intermedius, Streptococcus species, C. perfringens , and B. fragilis .

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Federal law restricts this drug to use by or on the order of a licensed veterinarian

Side Effects

No approved side-effect narrative is linked yet.

openFDA reaction signals are available for Dog 56 and Cat 56 (view top reported reactions).

Top Reported Reactions (openFDA)

Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).

Dog
Digestive
Vomiting (107) Loss of appetite (53) Vomiting (2) Vomiting (2) Vomiting (2) Vomiting (2) Vomiting (2) Vomiting (2)
Neurologic
Tiredness (lethargy) (63) Head tilt - neurological disorder (2) Head tilt - neurological disorder (2) Head tilt - neurological disorder (2) Head tilt - neurological disorder (2) Head tilt - neurological disorder (2) Head tilt - neurological disorder (2)
Effectiveness
Lack of efficacy - NOS (48)
Other
Death by euthanasia (67) Other abnormal test result NOS (51) Not eating (47) Death (39) Collapse NOS (2) Collapse NOS (2) Collapse NOS (2) Collapse NOS (2) Collapse NOS (2) Collapse NOS (2) Elevated globulins (2) Elevated globulins (2) Elevated globulins (2) Elevated globulins (2) Elevated globulins (2) Elevated globulins (2) Elevated total bilirubin (2) Elevated total bilirubin (2) Elevated total bilirubin (2) Elevated total bilirubin (2) Elevated total bilirubin (2) Elevated total bilirubin (2) Hyperaesthesia (2) Hyperaesthesia (2) Hyperaesthesia (2) Hyperaesthesia (2) Hyperaesthesia (2) Hyperaesthesia (2) Hyperalbuminaemia (2) Hyperalbuminaemia (2) Hyperalbuminaemia (2) Hyperalbuminaemia (2) Hyperalbuminaemia (2) Hyperalbuminaemia (2) Hyperproteinaemia (2) Hyperproteinaemia (2) Hyperproteinaemia (2) Hyperproteinaemia (2) Hyperproteinaemia (2) Hyperproteinaemia (2)
Cat
Digestive
Decreased appetite (19) Vomiting (19)
Skin & allergy
Application site hair loss (1) Application site hair loss (1) Application site hair loss (1) Application site hair loss (1) Application site hair loss (1) Application site hair loss (1)
Neurologic
Tiredness (lethargy) (34) Unsteady walking (ataxia) (25) Unsteady walking (ataxia) (1) Unsteady walking (ataxia) (1) Unsteady walking (ataxia) (1) Unsteady walking (ataxia) (1) Unsteady walking (ataxia) (1)
Other
Not eating (31) Death (25) Death by euthanasia (23) Weight loss (19) Not eating (2) Not eating (2) Not eating (2) Not eating (2) Not eating (2) Not eating (2) Administration error NOS (1) Administration error NOS (1) Administration error NOS (1) Administration error NOS (1) Administration error NOS (1) Application site excoriation (1) Application site excoriation (1) Application site excoriation (1) Application site excoriation (1) Application site excoriation (1) Application site excoriation (1) Death (1) Death (1) Death (1) Death (1) Death (1) Death (1) Dehydration (1) Dehydration (1) Dehydration (1) Dehydration (1) Dehydration (1) Dilated pupils (1) Dilated pupils (1) Dilated pupils (1) Dilated pupils (1) Dilated pupils (1) Dilated pupils (1) Hiding (1) Increased skin sensitivity (1) Licking (1)

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Sheepdog - Shetland, Female, 4.5 year, 9 kilogram • Drug: MSK, Unknown • Reactions: Inappropriate urination, Polyuria • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-055980
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 4.50 Year
  • Weight: 9.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Inappropriate urination Polyuria
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Male, 7 year, 6.4 kilogram • Drug: MSK, Oral • Reactions: Application site excoriation, Application site hair loss • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055392
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 7.00 Year
  • Weight: 6.400 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
Reactions Reported:
Application site excoriation Application site hair loss
Outcomes: Ongoing

Dog, ['Coonhound (unspecified)', 'Dog (unknown)'], Male, 5 year, 34.382 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Hives • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-053111
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 5.00 Year
  • Weight: 34.382 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Hives
Outcomes: Recovered/Normal

Dog, Retriever - Chesapeake Bay, Female, 5 year, 22.498 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Not drinking, Vomiting, Tremors, Walking difficulty, Hyperaesthesia… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055136
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 5.00 Year
  • Weight: 22.498 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Unassigned
Reactions Reported:
Not drinking Vomiting Tremors Walking difficulty Hyperaesthesia Head tilt - neurological disorder Collapse NOS Elevated total bilirubin Hyperproteinaemia Hyperalbuminaemia Elevated globulins
Outcomes: Ongoing

Cat, Siamese, Male, 15 year, 5.171 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Skin lesion NOS, Skin disorders NOS, Licking, Increased skin sensitivity, Skin necrosis • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-052046
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 15.00 Year
  • Weight: 5.171 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Skin lesion NOS Skin disorders NOS Licking Increased skin sensitivity Skin necrosis
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 4.5 year, 6.98 kilogram • Drug: MSK, Oral • Reactions: Hiding, Open mouth breathing, Not urinating, Not drinking, Sedation… • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-051262
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 4.50 Year
  • Weight: 6.980 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
Reactions Reported:
Hiding Open mouth breathing Not urinating Not drinking Sedation Not eating Dilated pupils Death Stiffness NOS
Outcomes: Died

Cat, Manx, Female, 3 year, 3.629 kilogram • Drug: MSK • Reactions: Vocalisation, Unequal pupils • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-050802
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 3.00 Year
  • Weight: 3.629 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
Reactions Reported:
Vocalisation Unequal pupils
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Male, 14 year, 5.352 kilogram • Drug: MSK • Reactions: Not eating, Underdose • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-051985
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 14.00 Year
  • Weight: 5.352 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
Reactions Reported:
Not eating Underdose
Outcomes: Outcome Unknown

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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