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Diazepam

Detailed information about Diazepam

Official label facts Owner quick guide first Marketing clearly labeled
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Pet Owner Quick Guide

Start here: what this medicine is for, what it does, and when it's usually needed.

Usually used for:

As a preanesthetic agent to reduce the amount of barbiturate required for short duration anesthesia.

What it does:

As a preanesthetic agent to reduce the amount of barbiturate required for short duration anesthesia.

When it's needed:

Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a license...

Call your vet sooner if you notice:

  • Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Commonly reported reactions:

  • (2 reports)
  • (2 reports)
  • (1 reports)

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
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Diazepam

Diazepam

Drug type: Generic ingredient • Branded profile • FDA branded products available

Species: Both

Manufacturer: MSK

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: MSK
Form: Liquid (Solution)
Identifiers:
NADA: 140848
Source metadata:

Warnings / Contraindications

Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

  • High: Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
32
Species represented
2
Most Reported Reactions
Reaction Cases Species Serious cases
2 Cat, Dog 2
2 Cat, Dog 2
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1

Species coverage: Dog (22) Cat (10)

View detailed reaction table
Reaction Species Seriousness Frequency Reports
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Source metadata:

Storage & Handling

No storage/handling guidance is linked yet.

Source metadata: No source yet.

Documents

Official label facts are separated from secondary summaries.

Official documents: 2 • Secondary summaries: 0

Official label facts
Secondary summaries

No source yet.

Source metadata:

Promotional Materials (Marketing)

This content is marketing material and not clinical guidance.

No marketing assets are linked yet.

No source yet.

Source metadata: No source yet.
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Technical appendix (vet reference)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 16, 2026, 11:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:22 AM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: Veteeze® Injection
Case-reported brands (openFDA): MSK
Catalog species: Both • FDA-labeled species: Dog
Rx/OTC: RX
Form/route: Liquid (Solution) • Intravenous
Applications: NADA 140-848
Documents: 1 (FOI: 1) • SPL: 1 • Label highlights • Official documents
Safety (openFDA)
Top reactions: Dog 56 • Cat 32 • View
Case summaries: 10 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian. (Contraindication, High)
Top reaction signals
Abdominal pain (1) Abnormal menace reflex test (1) Abnormal pupil light reflex (1) Abnormal ultrasound finding (1) Administration error NOS (1) Anaphylaxis (1) Ataxia (1) Behavioural disorder NOS (1) Bloody diarrhoea (1) Chattering of teeth (1) Conjunctival oedema (1) Constricted pupils (1) Death (1) Decreased activity (1) Decreased appetite (1) Dehiscence (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
NADA: 140848

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

Data Sources & Revision History

Every non-trivial field is expected to include provenance and update timestamps.

Official 4 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal l… (Official, 2026-02-12)
  • side_effects: Top reported reactions (openFDA): Seizure NOS, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Death, Death by euthanasia, A… (Official, 2026-02-12)
  • usage: As a preanesthetic agent to reduce the amount of barbiturate required for short duration anesthesia. (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Veteeze® Injection
RX
Diazepam
Liquid (Solution) • Intravenous
Label highlights
Official documents
Roche Vitamins, Inc. NADA 140-848 W Aug 24, 2017

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
Each milliliter of sterile solution contains 5 milligrams of diazepam.
Dogs
Indication
As a preanesthetic agent to reduce the amount of barbiturate required for short duration anesthesia.
Dosage
Intravenously, 0.2 milligram per kilogram of body weight 3-5 minutes before anesthesia is to be induced using a short acting barbiturate.
Limitations
Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Official Documents (FDA)

Direct links to FDA-hosted PDFs and SPL packages (when available).

Documents
  • Summary

    As a preanesthetic agent to reduce the amount barbiturate required for short duration anesthesia in dogs.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Usage

As a preanesthetic agent to reduce the amount of barbiturate required for short duration anesthesia.

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Side Effects

No approved side-effect narrative is linked yet.

openFDA reaction signals are available for Dog 56 and Cat 32 (view top reported reactions).

Top Reported Reactions (openFDA)

Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).

Dog
Digestive
Vomiting (74) Bloody diarrhoea (1) Bloody diarrhoea (1) Bloody diarrhoea (1) Bloody diarrhoea (1) Bloody diarrhoea (1) Bloody diarrhoea (1)
Neurologic
Seizure NOS (130) Tiredness (lethargy) (64) Unsteady walking (ataxia) (39) Seizure NOS (2) Seizure NOS (2) Seizure NOS (2) Seizure NOS (2) Seizure NOS (2) Seizure NOS (2) Unsteady walking (ataxia) (1) Unsteady walking (ataxia) (1) Unsteady walking (ataxia) (1) Unsteady walking (ataxia) (1) Unsteady walking (ataxia) (1) Unsteady walking (ataxia) (1)
Other
Death (57) Death by euthanasia (56) Other abnormal test result NOS (36) Elevated alanine aminotransferase (34) Death (2) Death (2) Death (2) Death (2) Death (2) Death (2) Abdominal pain (1) Abdominal pain (1) Abdominal pain (1) Abdominal pain (1) Abdominal pain (1) Abdominal pain (1) Abnormal menace reflex test (1) Abnormal menace reflex test (1) Abnormal menace reflex test (1) Abnormal menace reflex test (1) Abnormal menace reflex test (1) Abnormal menace reflex test (1) Abnormal pupil light reflex (1) Abnormal pupil light reflex (1) Abnormal pupil light reflex (1) Abnormal pupil light reflex (1) Abnormal pupil light reflex (1) Abnormal pupil light reflex (1) Abnormal ultrasound finding (1) Abnormal ultrasound finding (1) Abnormal ultrasound finding (1) Abnormal ultrasound finding (1) Abnormal ultrasound finding (1) Abnormal ultrasound finding (1)
Cat
Neurologic
Seizure NOS (27) Tiredness (lethargy) (19) Unsteady walking (ataxia) (17)
Behavior
Behavioral disorder (unspecified) (17)
Other
Death (23) Death by euthanasia (20) Elevated blood urea nitrogen (16) Not eating (16) Anaphylaxis (1) Anaphylaxis (1) Anaphylaxis (1) Anaphylaxis (1) Anaphylaxis (1) Anaphylaxis (1) Conjunctival oedema (1) Conjunctival oedema (1) Conjunctival oedema (1) Conjunctival oedema (1) Conjunctival oedema (1) Conjunctival oedema (1) Oedema NOS (1) Oedema NOS (1) Oedema NOS (1) Oedema NOS (1) Oedema NOS (1) Oedema NOS (1) Pharyngeal disorder (1) Pharyngeal disorder (1) Pharyngeal disorder (1) Pharyngeal disorder (1) Pharyngeal disorder (1) Pharyngeal disorder (1)

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, ['Collie (unspecified)', 'Dog (unknown)'], Female, 11 year, 18.234 kilogram • Drug: MSK, Unknown • Reactions: Decreased activity, Otitis NOS, Mucous stool, Bloody diarrhoea, Loss of hearing • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055634
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 11.00 Year
  • Weight: 18.234 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Decreased activity Otitis NOS Mucous stool Bloody diarrhoea Loss of hearing
Outcomes: Ongoing

Dog, Sheepdog - Old English (Bobtail), Male, 4 year, 37.8 kilogram • Drug: MSK, Unknown • Reactions: Malaise, Gastric ulcer, Peritonitis, Fluid in abdomen NOS, Fluid in abdomen NOS… • Outcome: Euthanized

  • Report ID: DEU-USFDACVM-2025-DE-000039
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 4.00 Year
  • Weight: 37.800 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Malaise Gastric ulcer Peritonitis Fluid in abdomen NOS Fluid in abdomen NOS Abdominal pain Vomiting Abnormal ultrasound finding Death Hyperthermia
Outcomes: Euthanized

Dog, Retriever - Labrador, Male, 6 month, 20.094 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Vomiting, Drooping eyelid, Unsteady walking (ataxia), Dehydration, Abnormal menace reflex test… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055350
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 6.00 Month
  • Weight: 20.094 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Vomiting Drooping eyelid Unsteady walking (ataxia) Dehydration Abnormal menace reflex test Hyperglycaemia Dilated pupils Seizure NOS Lateral recumbency Strabismus Vertical nystagmus Abnormal pupil light reflex Tremors Dry mucous membrane Injected sclera Wobbliness
Outcomes: Ongoing

Dog, Shepherd Dog - Australian, Female, 10 year, 13.608 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Death, Not eating, Not drinking, Dermatitis, Not himself/herself… • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-051487
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 10.00 Year
  • Weight: 13.608 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Death Not eating Not drinking Dermatitis Not himself/herself Swollen eye Fever Star-gazing Constricted pupils Trembling Lymphopenia Elevated blood urea nitrogen Hypernatremia Hyperchloraemia Hypokalaemia Medication error NOS Seizure NOS Hot spot
Outcomes: Died

Cat, European, Unknown • Drug: MSK, Intravenous • Reactions: Pharyngeal disorder, Oedema NOS, Anaphylaxis, Conjunctival oedema • Outcome: Recovered/Normal

  • Report ID: DEU-USFDACVM-2025-DE-000033
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Unknown
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intravenous
Reactions Reported:
Pharyngeal disorder Oedema NOS Anaphylaxis Conjunctival oedema
Outcomes: Recovered/Normal

Dog, Retriever - Golden, Male, 12 year, 37 kilogram • Drug: MSK, Unknown • Reactions: Lack of efficacy (endoparasite) - hookworm • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-046860
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 12.00 Year
  • Weight: 37.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Lack of efficacy (endoparasite) - hookworm
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Female, 11 year, 4.08 kilogram • Drug: MSK, Intravenous, Dose: 0.20 mL per animal • Reactions: Tiredness (lethargy), Drooling, Dehydration, Loose stool, Decreased appetite… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-047799
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 11.00 Year
  • Weight: 4.080 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intravenous
  • Dose: 0.20 mL per animal
Reactions Reported:
Tiredness (lethargy) Drooling Dehydration Loose stool Decreased appetite Dehiscence Necrosis NOS Tear flow increased Itching Respiratory signs
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 7 year, 6.35 kilogram • Drug: MSK, Unknown • Reactions: Tremors, Seizure NOS, Chattering of teeth, Hypothermia, Weakness… • Outcome: Ongoing, Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-041919
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 7.00 Year
  • Weight: 6.350 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Tremors Seizure NOS Chattering of teeth Hypothermia Weakness Walking difficulty Behavioral disorder (unspecified) Product label issues Mixed Product
Outcomes: Ongoing, Recovered/Normal

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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