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Meds A-Z

Phenylpropropanolamine Hcl

Detailed information about Phenylpropropanolamine Hcl

Official label facts Owner quick guide first Marketing clearly labeled
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Pet Owner Quick Guide

Start here: what this medicine is for, what it does, and when it's usually needed.

Usually used for:

Use this medication only when your veterinarian confirms it matches your pet's condition.

What it does:

Use this medication only when your veterinarian confirms it matches your pet's condition.

When it's needed:

Use this medication only when your veterinarian confirms it matches your pet's condition.

Commonly reported reactions:

  • (2 reports)
  • (1 reports)
  • (1 reports)

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
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Phenylpropropanolamine Hcl

Phenylpropropanolamine Hcl

Drug type: Generic ingredient • Generic profile No FDA branded products linked

Species: Both

Manufacturer: MSK

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: MSK
Form: No source yet
Identifiers:

No source yet.

Source metadata: No source yet.

Warnings / Contraindications

No contraindication summary is linked yet.

No owner-focused warning rows are linked yet.

Source metadata: No source yet.

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
29
Serious reports
26
Species represented
2
Most Reported Reactions
Reaction Cases Species Serious cases
2 Cat, Dog 2
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1

Species coverage: Dog (23) Cat (9)

View detailed reaction table
Reaction Species Seriousness Frequency Reports
Cat Serious - 1
Cat Non-serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Non-serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Non-serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Unknown - -
Cat Unknown - -
Dog Unknown - -
Source metadata:

Storage & Handling

No storage/handling guidance is linked yet.

Source metadata: No source yet.

Documents

Official label facts are separated from secondary summaries.

No linked label PDFs or safety notices yet.

Official label facts

No source yet.

Secondary summaries

No source yet.

Source metadata: No source yet.

Promotional Materials (Marketing)

This content is marketing material and not clinical guidance.

No marketing assets are linked yet.

No source yet.

Source metadata: No source yet.
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Technical appendix (vet reference)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 16, 2026, 11:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:22 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 56 Cat 7 View
Case summaries: 7 (showing 7) View
openFDA reports are unverified and do not prove causation.

Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Accidental exposure (1) Administration error NOS (1) Ataxia (1) Balance problem (1) Bradycardia (1) Death (1) Drug administration duration too long (1) Elevated alanine aminotransferase (ALT) (1) Elevated blood urea nitrogen (BUN) (1) Elevated serum alkaline phosphatase (ALP) (1) Elevated symmetrical dimethylarginine (SDMA) (1) Foaming at the mouth (1) Hyperkalaemia (1) Hyperphosphataemia (1) Hypoglycaemia (1) Hypothermia (1)

Data Sources & Revision History

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Vomiting, Overdose, Underdose, Lack of efficacy - NOS, Panting, Emesis (multiple). (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

No linked FDA product applications are available for this ingredient yet.

Usage

No approved usage text is linked yet for this ingredient.

  • Catalog species: Both
  • Safety reports available: 7 openFDA case summaries (view)

Contraindications

No approved contraindication text is linked yet. Review FDA label highlights and openFDA safety reports before making treatment decisions.

Side Effects

No approved side-effect narrative is linked yet.

openFDA reaction signals are available for Dog 56 and Cat 7 (view top reported reactions).

Top Reported Reactions (openFDA)

Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).

Dog
Digestive
Vomiting (134) Vomiting (75) Vomiting (2) Vomiting (2) Vomiting (2) Vomiting (2) Vomiting (2) Vomiting (2)
Neurologic
Tiredness (lethargy) (65) Unsteady walking (ataxia) (1) Unsteady walking (ataxia) (1) Unsteady walking (ataxia) (1) Unsteady walking (ataxia) (1) Unsteady walking (ataxia) (1) Unsteady walking (ataxia) (1)
Effectiveness
Lack of efficacy - NOS (109)
Other
Overdose (130) Underdose (121) Panting (90) Agitation (52) Overdose (2) Overdose (2) Overdose (2) Overdose (2) Overdose (2) Overdose (2) Balance problem (1) Balance problem (1) Balance problem (1) Balance problem (1) Balance problem (1) Balance problem (1) Death (1) Death (1) Death (1) Death (1) Death (1) Death (1) Drug administration duration too long (1) Drug administration duration too long (1) Drug administration duration too long (1) Drug administration duration too long (1) Drug administration duration too long (1) Drug administration duration too long (1) Elevated alanine aminotransferase (1) Elevated alanine aminotransferase (1) Elevated alanine aminotransferase (1) Elevated alanine aminotransferase (1) Elevated alanine aminotransferase (1) Elevated alanine aminotransferase (1) Elevated blood urea nitrogen (1) Elevated blood urea nitrogen (1) Elevated blood urea nitrogen (1) Elevated blood urea nitrogen (1) Elevated blood urea nitrogen (1) Elevated blood urea nitrogen (1)
Cat
Neurologic
Tiredness (lethargy) (1)
Other
Accidental exposure (1) Administration error NOS (1) Bradycardia (1) Foaming at the mouth (1) Hypothermia (1) Overdose (1)

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Doberman Pinscher, Female, 6 year, 43.545 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per dose, Frequency: 12 per hour • Reactions: Lack of efficacy - NOS, Death, Other abnormal test result NOS, Underdose, Drug administration duration too long • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-056129
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 6.00 Year
  • Weight: 43.545 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per dose
  • Frequency: 12 per hour
Reactions Reported:
Lack of efficacy - NOS Death Other abnormal test result NOS Underdose Drug administration duration too long
Outcomes: Died

Dog, Dog (unknown), Female • Drug: MSK, Tablet, chewable, Oral • Reactions: Urinary incontinence • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-056110
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
Reactions Reported:
Urinary incontinence
Outcomes: Outcome Unknown

Dog, Chihuahua, Female, 16 year, 4.536 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per dose, Frequency: 2 per day • Reactions: Pacing, Vomiting, Tiredness (lethargy), Balance problem, Unsteady walking (ataxia)… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-051235
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 16.00 Year
  • Weight: 4.536 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per dose
  • Frequency: 2 per day
Reactions Reported:
Pacing Vomiting Tiredness (lethargy) Balance problem Unsteady walking (ataxia) Hyperphosphataemia Elevated blood urea nitrogen Hypoglycaemia Weakness Elevated serum alkaline phosphatase Overdose Hyperkalaemia Elevated alanine aminotransferase Elevated symmetrical dimethylarginine
Outcomes: Outcome Unknown

Dog, Shih Tzu, Female, 13 year, 4.99 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 0.50 tablet per dose, Frequency: 12 per hour • Reactions: Urinary retention, Vomiting, Stranguria, Overdose • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-049912
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 13.00 Year
  • Weight: 4.990 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 0.50 tablet per dose
  • Frequency: 12 per hour
Reactions Reported:
Urinary retention Vomiting Stranguria Overdose
Outcomes: Outcome Unknown

Dog, Siberian Husky, Female, 7 year, 31.298 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per dose, Frequency: 12 per hour • Reactions: Vomiting, Elevated alanine aminotransferase, Underdose • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-049920
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 7.00 Year
  • Weight: 31.298 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per dose
  • Frequency: 12 per hour
Reactions Reported:
Vomiting Elevated alanine aminotransferase Underdose
Outcomes: Ongoing

Cat, Domestic Shorthair, Female, 16 year • Drug: MSK, Tablet, chewable, Oral, Frequency: 1 per day • Reactions: Foaming at the mouth, Administration error NOS • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2023-US-050503
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 16.00 Year
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Frequency: 1 per day
Reactions Reported:
Foaming at the mouth Administration error NOS
Outcomes: Recovered/Normal

Cat, Domestic Shorthair, Male, 11 year, 3.175 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per dose, Frequency: 1 per year • Reactions: Bradycardia, Hypothermia, Tiredness (lethargy), Accidental exposure, Overdose • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2020-US-065384
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 11.00 Year
  • Weight: 3.175 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per dose
  • Frequency: 1 per year
Reactions Reported:
Bradycardia Hypothermia Tiredness (lethargy) Accidental exposure Overdose
Outcomes: Recovered/Normal

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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