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Famotidine

Detailed information about Famotidine

Official label facts Owner quick guide first Marketing clearly labeled
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Pet Owner Quick Guide

Start here: what this medicine is for, what it does, and when it's usually needed.

Usually used for:

Acid-reducing medication used for GI upset and reflux.

What it does:

Acid-reducing medication used for GI upset and reflux.

When it's needed:

Dose adjustments may be needed in kidney disease.

Call your vet sooner if you notice:

  • Dose adjustments may be needed in kidney disease.

Commonly reported reactions:

  • (2 reports)
  • (1 reports)
  • (1 reports)

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
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Famotidine

Famotidine

Drug type: Generic ingredient • Generic profile • No FDA branded products linked

Species: Both

Manufacturer: MSK

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: MSK
Form: No source yet
Identifiers:

No source yet.

Source metadata: No source yet.

Warnings / Contraindications

Dose adjustments may be needed in kidney disease.

  • High: Dose adjustments may be needed in kidney disease.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
23
Species represented
2
Most Reported Reactions
Reaction Cases Species Serious cases
2 Cat, Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Cat 1
1 Dog 1

Species coverage: Dog (23) Cat (9)

View detailed reaction table
Reaction Species Seriousness Frequency Reports
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Non-serious - 1
Dog Serious - 1
Cat Non-serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Non-serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Non-serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Non-serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Non-serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Non-serious - 1
Cat Non-serious - 1
Cat Non-serious - 1
Source metadata:

Storage & Handling

Store at room temperature.

Source metadata: No source yet.

Documents

Official label facts are separated from secondary summaries.

No linked label PDFs or safety notices yet.

Official label facts

No source yet.

Secondary summaries

No source yet.

Source metadata: No source yet.

Promotional Materials (Marketing)

This content is marketing material and not clinical guidance.

No marketing assets are linked yet.

No source yet.

Source metadata: No source yet.
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Technical appendix (vet reference)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 7:40 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 16, 2026, 11:02 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:19 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 56 • Cat 56 • View
Case summaries: 10 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Dose adjustments may be needed in kidney disease. (Contraindication, High)
Top reaction signals
Abnormal radiograph finding (1) Acid-base disorder (1) Anorexia (1) Arthritis (1) Ataxia (1) Bacterial skin infection NOS (1) Balance impaired (1) Behavioural disorder NOS (1) Bradycardia (1) Cognitive disorder NOS (1) Corneal ulcer (1) Decreased appetite (1) Depressed reflexes (1) Diarrhoea (1) Dyspnoea (1) Elevated blood urea nitrogen (BUN) (1)

Data Sources & Revision History

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 3 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-02-12)
  • storage_handling: Store at room temperature. (Clinical, 2026-02-12)
  • usage: Acid-reducing medication used for GI upset and reflux. (Clinical, 2026-02-12)
  • side_effects: Generally well tolerated; occasional GI upset. (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

No linked FDA product applications are available for this ingredient yet.

Usage

Acid-reducing medication used for GI upset and reflux.

Contraindications

Dose adjustments may be needed in kidney disease.

Side Effects

Generally well tolerated; occasional GI upset.

Source: FDA openFDA • Reference

Top Reported Reactions (openFDA)

Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).

Dog
Digestive
Vomiting (566) Diarrhea (313) Loss of appetite (212) Vomiting (6) Vomiting (6) Vomiting (6) Vomiting (6) Vomiting (5) Vomiting (5) Loss of appetite (4) Loss of appetite (4) Loss of appetite (4) Loss of appetite (4) Loss of appetite (4) Loss of appetite (4) Decreased appetite (3) Decreased appetite (3) Decreased appetite (3) Diarrhea (3) Diarrhea (3) Diarrhea (3)
Neurologic
Tiredness (lethargy) (347) Tiredness (lethargy) (7) Tiredness (lethargy) (7) Tiredness (lethargy) (7) Tiredness (lethargy) (7) Tiredness (lethargy) (7) Tiredness (lethargy) (7)
Behavior
Behavioral disorder (unspecified) (3) Behavioral disorder (unspecified) (3) Behavioral disorder (unspecified) (3) Behavioral disorder (unspecified) (3)
Other
Death by euthanasia (211) Elevated alanine aminotransferase (185) Not eating (173) Death (164) Death by euthanasia (4) Death by euthanasia (4) Death by euthanasia (4) Death by euthanasia (4) Death (3) Death (3) Death (3) Death (3) Death (3) Death by euthanasia (3) Death by euthanasia (3) Elevated blood urea nitrogen (3) Elevated blood urea nitrogen (3) Elevated blood urea nitrogen (3) Hyperphosphataemia (3) Hyperphosphataemia (3) Hyperphosphataemia (3) Leucocytosis NOS (3) Leucocytosis NOS (3) Sleepiness - systemic disorder (3)
Cat
Digestive
Vomiting (47) Loss of appetite (44) Diarrhea (31)
Neurologic
Tiredness (lethargy) (42)
Other
Weight loss (38) Not eating (37) Death (29) Death by euthanasia (27) Bradycardia (2) Bradycardia (2) Bradycardia (2) Bradycardia (2) Bradycardia (2) Bradycardia (2) Hypotension (2) Hypotension (2) Hypotension (2) Hypotension (2) Hypotension (2) Hypotension (2) Increased respiratory rate (2) Increased respiratory rate (2) Increased respiratory rate (2) Increased respiratory rate (2) Increased respiratory rate (2) Increased respiratory rate (2) Vocalisation (2) Vocalisation (2) Vocalisation (2) Vocalisation (2) Vocalisation (2) Vocalisation (2) Weight loss (2) Weight loss (2) Weight loss (2) Weight loss (2) Weight loss (2) Weight loss (2) Abnormal radiograph finding (1) Abnormal radiograph finding (1) Abnormal radiograph finding (1) Abnormal radiograph finding (1) Abnormal radiograph finding (1) Abnormal radiograph finding (1) Elevated blood urea nitrogen (1) Elevated blood urea nitrogen (1) Elevated blood urea nitrogen (1) Elevated blood urea nitrogen (1) Elevated blood urea nitrogen (1) Elevated blood urea nitrogen (1) Elevated globulins (1) Elevated globulins (1) Elevated globulins (1) Elevated globulins (1) Elevated globulins (1) Elevated globulins (1)

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Chihuahua, Female, 16 year, 3.12 kilogram • Drug: MSK, Unknown • Reactions: Reduced responses, Elevated creatinine, Corneal ulcer, Sleepiness - systemic disorder, Elevated blood urea nitrogen… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055817
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 16.00 Year
  • Weight: 3.120 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Reduced responses Elevated creatinine Corneal ulcer Sleepiness - systemic disorder Elevated blood urea nitrogen Lack of efficacy - NOS Hyperphosphataemia
Outcomes: Ongoing

Cat, Cat (other), Male, 13 year, 3.49 kilogram • Drug: MSK, Unknown • Reactions: Slow heart rate, Recovery prolonged • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-055510
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 13.00 Year
  • Weight: 3.490 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Slow heart rate Recovery prolonged
Outcomes: Recovered/Normal

Dog, Terrier - Bull - American Pit, Male, 14 year, 24.494 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Stiff gait, Cognitive disorder NOS, Malaise, Vomiting, Diarrhea… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055236
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 14.00 Year
  • Weight: 24.494 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Stiff gait Cognitive disorder NOS Malaise Vomiting Diarrhea Hind limb paresis Unable to stand Unable to walk Proprioception deficit Tremors Fever Unsteady walking (ataxia) Behavioral disorder (unspecified)
Outcomes: Ongoing

Dog, Dog (unknown), Male, 10 year, 32.659 kilogram • Drug: MSK, Unknown • Reactions: Mass NOS, Lymph node abscess, Lymphadenopathy, Tachycardia, Drooling… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-055759
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 10.00 Year
  • Weight: 32.659 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Mass NOS Lymph node abscess Lymphadenopathy Tachycardia Drooling Elevated serum alkaline phosphatase Monocytosis Neutrophilia Leucocytosis NOS Acid-base disorder Musculoskeletal disorder NOS Luxation/subluxation Arthritis Muscle tremor Tachypnoea Trouble breathing (dyspnea) Bacterial skin infection NOS Trauma NOS Hyperthermia Loss of appetite Oedema NOS Tiredness (lethargy) General pain
Outcomes: Outcome Unknown

Dog, Shepherd Dog - Australian, Male, 13 year • Drug: MSK, Tablet, Oral, Dose: 20 Milligram per animal, Frequency: 12 per hour • Reactions: Gait abnormality, Balance impaired, Whining, Lameness, Proprioception deficit… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-054764
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 13.00 Year
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 20 Milligram per animal
  • Frequency: 12 per hour
Reactions Reported:
Gait abnormality Balance impaired Whining Lameness Proprioception deficit Depressed reflexes Loss of strength
Outcomes: Ongoing

Dog, ['Hound - Basset', 'Dog (unknown)'], Female, 8.9 year, 16.33 kilogram • Drug: MSK, Tablet, Oral, Dose: 10 Milligram per animal, Frequency: 12 per hour • Reactions: Diarrhea, Vomiting, Decreased appetite, Low thyroxine • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-055287
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 8.90 Year
  • Weight: 16.330 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 10 Milligram per animal
  • Frequency: 12 per hour
Reactions Reported:
Diarrhea Vomiting Decreased appetite Low thyroxine
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Female, 15 year, 3.402 kilogram • Drug: MSK, Tablet, Unknown • Reactions: Weight loss, Medication error NOS, Vomiting, Not eating, Weakness… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-053375
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 15.00 Year
  • Weight: 3.402 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Tablet
Reactions Reported:
Weight loss Medication error NOS Vomiting Not eating Weakness Tiredness (lethargy) Elevated globulins Lymphopenia Abnormal radiograph finding Gastroenteritis Musculoskeletal disorder NOS Lack of efficacy - NOS
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 13 year, 6.35 kilogram • Drug: MSK, Unknown • Reactions: Hyperglycaemia, Elevated blood urea nitrogen, Poor coat condition, Weight loss, Hypochloraemia… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-052366
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 13.00 Year
  • Weight: 6.350 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Hyperglycaemia Elevated blood urea nitrogen Poor coat condition Weight loss Hypochloraemia Polyuria Polydipsia
Outcomes: Outcome Unknown

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

Store at room temperature.

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