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Meds A-Z

Omeprazole

Detailed information about Omeprazole

Official label facts Owner quick guide first Marketing clearly labeled
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Pet Owner Quick Guide

Start here: what this medicine is for, what it does, and when it's usually needed.

Usually used for:

For treatment and prevention of recurrence of gastric ulcers in horses and foals 4 weeks of age and older.

What it does:

Proton pump inhibitor used to reduce stomach acid (ulcers, reflux).

When it's needed:

Use caution with liver disease; check interactions with other medications.

Call your vet sooner if you notice:

  • Use caution with liver disease; check interactions with other medications.

Commonly reported reactions:

  • (2 reports)
  • (1 reports)
  • (1 reports)

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
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Omeprazole

Omeprazole

Drug type: Generic ingredient • Branded profile FDA branded products available

Species: Both

Manufacturer: MSK

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: MSK
Form: Paste
Identifiers:
NADA: 141123 NADA: 141227 NDC Package: 0010-3704-01 NDC Package: 0010-3704-02 NDC Package: 0010-9719-01 NDC Package: 0010-9719-02 NDC Package: 58597-7030-8 NDC Package: 58597-7030-9 NDC Package: 62157-643-01 NDC Package: 62157-807-01 NDC Package: 73309-128-01 NDC Package: 86065-002-01 NDC Package: 86213-221-01 NDC Package: 86213-221-02 NDC Package: 86213-222-01 NDC Package: 86213-222-02 NDC Package: 86213-223-01 NDC Package: 86213-223-02 NDC Product: 0010 NDC Product: 58597
Source metadata:

Warnings / Contraindications

Use caution with liver disease; check interactions with other medications.

  • High: Use caution with liver disease; check interactions with other medications.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
31
Species represented
2
Most Reported Reactions
Reaction Cases Species Serious cases
2 Cat, Dog 2
1 Dog 1
1 Cat 1
1 Cat 1
1 Dog 1
1 Cat 1
1 Dog 1
1 Cat 1

Species coverage: Cat (18) Dog (14)

View detailed reaction table
Reaction Species Seriousness Frequency Reports
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Non-serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Serious - 1
Source metadata:

Storage & Handling

Store at room temperature.

Source metadata: No source yet.

Documents

Official label facts are separated from secondary summaries.

Promotional Materials (Marketing)

This content is marketing material and not clinical guidance.

No marketing assets are linked yet.

No source yet.

Source metadata: No source yet.
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Technical appendix (vet reference)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 7:40 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 16, 2026, 11:02 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:19 AM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: GastroGard® UlcerGard®
Case-reported brands (openFDA): MSK
Catalog species: Both FDA-labeled species: Horse
Rx/OTC: OTC, RX
Form/route: Paste Oral
Applications: NADA 141-123 • NADA 141-227
Documents: 2 (FOI: 2) • SPL: 2 Label highlights Official documents
Safety (openFDA)
Top reactions: Dog 56 Cat 56 View
Case summaries: 10 (showing 8) View
openFDA reports are unverified and do not prove causation.

Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Use caution with liver disease; check interactions with other medications. (Contraindication, High)
Top reaction signals
Abdominal pain (1) Accidental exposure (1) Acute renal failure (1) Adipsia (1) Anaemia NOS (1) Anorexia (1) Ataxia (1) Behavioural disorder NOS (1) Blood in vomit (1) Cognitive disorder NOS (1) Death (1) Death by euthanasia (1) Death by euthanasia (1) Dehiscence (1) Dehydration (1) Diarrhoea (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
NADA: 141123 NADA: 141227 NDC Package: 0010-3704-01 NDC Package: 0010-3704-02 NDC Package: 0010-9719-01 NDC Package: 0010-9719-02 NDC Package: 58597-7030-8 NDC Package: 58597-7030-9 NDC Package: 62157-643-01 NDC Package: 62157-807-01 NDC Package: 73309-128-01 NDC Package: 86065-002-01 NDC Package: 86213-221-01 NDC Package: 86213-221-02 NDC Package: 86213-222-01 NDC Package: 86213-222-02 NDC Package: 86213-223-01 NDC Package: 86213-223-02 NDC Product: 0010 NDC Product: 58597 NDC Product: 62157 NDC Product: 73309 NDC Product: 86065 NDC Product: 86213
Package NDC Product NDC Form / Route Status
0010-3704-01 0010 -
0010-3704-02 0010 -
0010-9719-01 0010 -
0010-9719-02 0010 -
58597-7030-8 58597 -
58597-7030-9 58597 -
62157-643-01 62157 -
62157-807-01 62157 -
73309-128-01 73309 -
86065-002-01 86065 -
86213-221-01 86213 -
86213-221-02 86213 -
86213-222-01 86213 -
86213-222-02 86213 -
86213-223-01 86213 -
86213-223-02 86213 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

  • ucm118038.pdf • FOI summary • Official • June 1, 2016
    FDA FOI summary for application 141227
  • ucm117173.pdf • FOI summary • Official • June 1, 2016
    FDA FOI summary for application 141123

Data Sources & Revision History

Every non-trivial field is expected to include provenance and update timestamps.

Official 5 Clinical 1 Manufacturer 0 Marketing 0
Current Field Facts
  • storage_handling: Store at room temperature. (Clinical, 2026-02-12)
  • contraindications: Use caution with liver disease; check interactions with other medications. (Official, 2026-02-12)
  • side_effects: Generally well tolerated; occasional GI upset. (Official, 2026-02-12)
  • usage: Proton pump inhibitor used to reduce stomach acid (ulcers, reflux). (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
GastroGard®
RX
Omeprazole
Paste Oral
Boehringer lngelheim Animal Health USA, Inc. NADA 141-123 Approved Jun 1, 2016
UlcerGard®
OTC
Omeprazole
Paste Oral
Boehringer lngelheim Animal Health USA, Inc. NADA 141-227 Approved Jun 1, 2016

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Horse, Not For Meat Production • Horse, Foals 4 Weeks And Older, Not For Food
Composition / specifications
Each syringe contains 2.28 g of omeprazole
Horses and Foals (4 Weeks of Age and Older)
Indication
For treatment and prevention of recurrence of gastric ulcers in horses and foals 4 weeks of age and older.
Dosage
For treatment of gastric ulcers, GastroGard Paste should be administered orally once-a-day for 4 weeks at the recommended dosage of 1.8 mg omeprazole/lb body weight (4 mg/kg). For the prevention of recurrence of gastric ulcers, continue treatment for at least an additional 4 weeks by administering GastroGard Paste at the recommended daily maintenance dose of 0.9 mg/lb (2 mg/kg).
Limitations
Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. The safety of GastroGard Paste has not been determined in pregnant or lactating mares.

FDA page: Open in Animal Drugs @ FDA

Species: Horse, No Use Class Stated Or Implied
Composition / specifications
Each syringe contains 2.28 g of omeprazole
Horses
Indication
For the prevention of gastric ulcers in horses.
Dosage
The minimum recommended dosage is 1 mg/kg per day (0.45 mg/lb) or 1/4 syringe. Horses over 1,200 lb body weight should receive two doses per day.
Limitations

FDA page: Open in Animal Drugs @ FDA

Official Documents (FDA)

Direct links to FDA-hosted PDFs and SPL packages (when available).

Documents
  • Summary
    For the treatment and prevention of recurrence of gastric ulcers in horses and foals 4 weeks of age and older.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For the prevention of gastric ulcers.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Usage

Proton pump inhibitor used to reduce stomach acid (ulcers, reflux).

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Use caution with liver disease; check interactions with other medications.

Side Effects

Generally well tolerated; occasional GI upset.

Source: FDA openFDA • Reference

Top Reported Reactions (openFDA)

Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).

Dog
Digestive
Vomiting (229) Diarrhea (136) Loss of appetite (88) Decreased appetite (81) Vomiting (6) Vomiting (6) Vomiting (6) Vomiting (6) Vomiting (6) Vomiting (5) Decreased appetite (2) Decreased appetite (2) Decreased appetite (2) Decreased appetite (2) Decreased appetite (2) Decreased appetite (2)
Neurologic
Tiredness (lethargy) (113) Tiredness (lethargy) (85) Tiredness (lethargy) (4) Tiredness (lethargy) (4) Tiredness (lethargy) (4) Tiredness (lethargy) (4) Tiredness (lethargy) (4) Tiredness (lethargy) (4)
Behavior
Behavioral disorder (unspecified) (2) Behavioral disorder (unspecified) (2) Behavioral disorder (unspecified) (2) Behavioral disorder (unspecified) (2) Behavioral disorder (unspecified) (2) Behavioral disorder (unspecified) (2)
Other
Death by euthanasia (91) Not eating (90) Death (3) Death (3) Death (3) Death (3) Death (3) Death (3) Acute renal failure (2) Acute renal failure (2) Acute renal failure (2) Acute renal failure (2) Acute renal failure (2) Acute renal failure (2) Death by euthanasia (2) Death by euthanasia (2) Death by euthanasia (2) Death by euthanasia (2) Death by euthanasia (2) Death by euthanasia (2) Elevated blood urea nitrogen (2) Elevated blood urea nitrogen (2) Elevated blood urea nitrogen (2) Elevated blood urea nitrogen (2) Elevated blood urea nitrogen (2) Elevated blood urea nitrogen (2)
Cat
Digestive
Loss of appetite (5) Haemorrhagic diarrhoea (1) Haemorrhagic diarrhoea (1) Haemorrhagic diarrhoea (1) Haemorrhagic diarrhoea (1) Haemorrhagic diarrhoea (1) Haemorrhagic diarrhoea (1) Loss of appetite (1) Loss of appetite (1) Loss of appetite (1) Loss of appetite (1) Loss of appetite (1) Loss of appetite (1)
Neurologic
Tiredness (lethargy) (4)
Behavior
Behavioral disorder (unspecified) (4)
Other
Weight loss (5) Death (4) Anaemia NOS (3) Malaise (3) Abdominal pain (2) Adipsia (1) Adipsia (1) Adipsia (1) Adipsia (1) Adipsia (1) Adipsia (1) Anaemia NOS (1) Anaemia NOS (1) Anaemia NOS (1) Anaemia NOS (1) Anaemia NOS (1) Anaemia NOS (1) Dehydration (1) Dehydration (1) Dehydration (1) Dehydration (1) Dehydration (1) Dehydration (1) Elevated thyroxine (1) Elevated thyroxine (1) Elevated thyroxine (1) Elevated thyroxine (1) Elevated thyroxine (1) Elevated thyroxine (1) Haematemesis (1) Haematemesis (1) Haematemesis (1) Haematemesis (1) Haematemesis (1) Haematemesis (1) Hyperthermia (1) Hyperthermia (1) Hyperthermia (1) Hyperthermia (1) Hyperthermia (1) Hyperthermia (1)

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, ['Weimaraner', 'Retriever - Labrador'], Male, 14 year, 26.3 kilogram • Drug: MSK, Unknown • Reactions: Gait abnormality, Walking difficulty, Unsteady gait, Product label issues • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-054553
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 14.00 Year
  • Weight: 26.300 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Gait abnormality Walking difficulty Unsteady gait Product label issues
Outcomes: Ongoing

Dog, Terrier - Bull - American Pit, Male, 14 year, 24.494 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Stiff gait, Cognitive disorder NOS, Malaise, Vomiting, Diarrhea… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055236
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 14.00 Year
  • Weight: 24.494 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Stiff gait Cognitive disorder NOS Malaise Vomiting Diarrhea Hind limb paresis Unable to stand Unable to walk Proprioception deficit Tremors Fever Unsteady walking (ataxia) Behavioral disorder (unspecified)
Outcomes: Ongoing

Dog, Crossbred Canine/dog, Male, 4 year, 14.969 kilogram • Drug: MSK, Unassigned, Oral, Frequency: 1 per day • Reactions: Vomiting, Not eating, Elevated creatinine, Acute renal failure, Accidental exposure… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055034
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 4.00 Year
  • Weight: 14.969 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Unassigned
  • Frequency: 1 per day
Reactions Reported:
Vomiting Not eating Elevated creatinine Acute renal failure Accidental exposure Overdose
Outcomes: Ongoing

Dog, Bulldog - English, Male, 7 year, 45.359 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Vomiting • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-055385
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 7.00 Year
  • Weight: 45.359 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Unassigned
Reactions Reported:
Vomiting
Outcomes: Recovered/Normal

Dog, Terrier - Yorkshire, Male, 8 year, 3.629 kilogram • Drug: MSK, Tablet, Oral, Dose: 5 Milligram per dose, Frequency: 12 per hour • Reactions: Jaundice, Low blood urea nitrogen, Low creatinine, Hypokalaemia, Death by euthanasia • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2025-US-053982
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 8.00 Year
  • Weight: 3.629 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 5 Milligram per dose
  • Frequency: 12 per hour
Reactions Reported:
Jaundice Low blood urea nitrogen Low creatinine Hypokalaemia Death by euthanasia
Outcomes: Euthanized

Cat, Domestic Shorthair, Female, 15 year • Drug: MSK, Unknown • Reactions: Inappropriate defecation, Hyperthermia, Dehydration, Weight loss, Adipsia… • Outcome: Ongoing

  • Report ID: GBR-USFDACVM-2025-GB-000057
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 15.00 Year
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Inappropriate defecation Hyperthermia Dehydration Weight loss Adipsia Loss of appetite Polyuria Urine abnormalities NOS Elevated thyroxine Neutrophilia Anaemia NOS Nausea Stomatitis Lip disorder NOS Haemorrhagic diarrhoea Haematemesis
Outcomes: Ongoing

Cat, Domestic Shorthair, Female, 14 year • Drug: MSK, Unassigned, Unknown • Reactions: Blood in vomit, Tiredness (lethargy), Abdominal pain, Anaemia NOS, Elevated alanine aminotransferase… • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2025-US-047564
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 14.00 Year
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Blood in vomit Tiredness (lethargy) Abdominal pain Anaemia NOS Elevated alanine aminotransferase Melaena Death by euthanasia
Outcomes: Euthanized

Cat, Domestic Mediumhair, Male, 5 year, 4.06 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Dehiscence, Jaw disorder, Vomiting, Tiredness (lethargy), Loss of appetite… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-037529
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 5.00 Year
  • Weight: 4.060 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Dehiscence Jaw disorder Vomiting Tiredness (lethargy) Loss of appetite Pale mucous membrane Anaemia NOS Intentional misuse
Outcomes: Ongoing

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

Store at room temperature.

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