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Lokivetmab

Detailed information about Lokivetmab

Official label facts Owner quick guide first Marketing clearly labeled
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Pet Owner Quick Guide

Start here: what this medicine is for, what it does, and when it's usually needed.

Usually used for:

Monoclonal antibody used to reduce itch associated with atopic dermatitis in dogs.

What it does:

Monoclonal antibody used to reduce itch associated with atopic dermatitis in dogs.

When it's needed:

Discuss use in dogs with a history of severe allergic reactions.

Call your vet sooner if you notice:

  • Discuss use in dogs with a history of severe allergic reactions.

Commonly reported reactions:

  • (1 reports)
  • (1 reports)
  • (1 reports)

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
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Lokivetmab

Lokivetmab

Drug type: Generic ingredient • Generic profile No FDA branded products linked

Species: Dog

Manufacturer: MSK

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Dog
Manufacturer: MSK
Form: No source yet
Identifiers:

No source yet.

Source metadata: No source yet.

Warnings / Contraindications

Discuss use in dogs with a history of severe allergic reactions.

  • High: Discuss use in dogs with a history of severe allergic reactions.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
15
Serious reports
5
Species represented
1
Most Reported Reactions
Reaction Cases Species Serious cases
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 0
1 Dog 0
1 Dog 0

Species coverage: Dog (32)

View detailed reaction table
Reaction Species Seriousness Frequency Reports
Dog Serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Non-serious - 1
Dog Serious - 1
Dog Non-serious - 1
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Source metadata:

Storage & Handling

Refrigerate and protect from light; do not freeze.

Source metadata: No source yet.

Documents

Official label facts are separated from secondary summaries.

No linked label PDFs or safety notices yet.

Official label facts

No source yet.

Secondary summaries

No source yet.

Source metadata: No source yet.

Promotional Materials (Marketing)

This content is marketing material and not clinical guidance.

No marketing assets are linked yet.

No source yet.

Source metadata: No source yet.
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Technical appendix (vet reference)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 7:40 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 16, 2026, 11:02 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:19 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Dog
Safety (openFDA)
Top reactions: Dog 56 Cat 0 View
Case summaries: 5 (showing 5) View
openFDA reports are unverified and do not prove causation.

Explore
Related conditions: Atopic Dermatitis (Canine Atopy)
Linked using: Usage_Inferred (0.78)

Diagnosis Codes
ICD10_CM: L20.9
Atopic dermatitis, unspecified

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Discuss use in dogs with a history of severe allergic reactions. (Contraindication, High)
Top reaction signals
Application site discharge NOS (1) Application site itching (1) Application site reddening (1) Blood in urine (1) Deafness (1) Female reproductive tract disorder NOS (1) Inappropriate urination (1) Increased weight (1) Itching (1) Lethargy (see also Central nervous system depression in Neurological) (1) Loss of hearing (1) Pinnal ulcer (1) Pollakiuria (1) Tympanic rupture (1) Unclassifiable adverse event (1) Application site discharge NOS (reports: 1, since 2025-08-16) (0)

Data Sources & Revision History

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 3 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: Discuss use in dogs with a history of severe allergic reactions. (Clinical, 2026-02-12)
  • storage_handling: Refrigerate and protect from light; do not freeze. (Clinical, 2026-02-12)
  • usage: Monoclonal antibody used to reduce itch associated with atopic dermatitis in dogs. (Clinical, 2026-02-12)
  • side_effects: Injection site reactions, lethargy; generally well tolerated. (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

No linked FDA product applications are available for this ingredient yet.

Usage

Monoclonal antibody used to reduce itch associated with atopic dermatitis in dogs.

Contraindications

Discuss use in dogs with a history of severe allergic reactions.

Side Effects

Injection site reactions, lethargy; generally well tolerated.

Source: FDA openFDA • Reference

Top Reported Reactions (openFDA)

Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).

Dog
Digestive
Vomiting (19) Decreased appetite (16) Diarrhea (13)
Skin & allergy
Application site itching (1) Application site itching (1) Application site itching (1) Application site itching (1) Application site itching (1) Application site itching (1)
Neurologic
Tiredness (lethargy) (15) Tiredness (lethargy) (11)
Effectiveness
Lack of efficacy - NOS (26)
Other
Elevated serum alkaline phosphatase (13) Elevated alanine aminotransferase (11) Application site discharge NOS (1) Application site discharge NOS (1) Application site discharge NOS (1) Application site discharge NOS (1) Application site discharge NOS (1) Application site discharge NOS (1) Application site reddening (1) Application site reddening (1) Application site reddening (1) Application site reddening (1) Application site reddening (1) Application site reddening (1) Blood in urine (1) Blood in urine (1) Blood in urine (1) Blood in urine (1) Blood in urine (1) Blood in urine (1) Deafness (1) Deafness (1) Deafness (1) Deafness (1) Deafness (1) Deafness (1) Female reproductive tract disorder NOS (1) Female reproductive tract disorder NOS (1) Female reproductive tract disorder NOS (1) Female reproductive tract disorder NOS (1) Female reproductive tract disorder NOS (1) Female reproductive tract disorder NOS (1) Immediate pain upon injection (1) Immediate pain upon injection (1) Immediate pain upon injection (1) Immediate pain upon injection (1) Immediate pain upon injection (1) Inappropriate urination (1) Inappropriate urination (1) Inappropriate urination (1) Inappropriate urination (1) Inappropriate urination (1) Inappropriate urination (1) Increased weight (1)

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Terrier - Fox Wire, Male, 10.8 year, 9.68 kilogram • Drug: MSK, Subcutaneous, Dose: 30 Milligram per animal, Frequency: 1 per month • Reactions: Deafness, Tympanic rupture, Application site discharge NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-053873
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 10.80 Year
  • Weight: 9.680 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Dose: 30 Milligram per animal
  • Frequency: 1 per month
Reactions Reported:
Deafness Tympanic rupture Application site discharge NOS
Outcomes: Outcome Unknown

Dog, Shih Tzu, Female, 8 year, 4.627 kilogram • Drug: MSK, Injection, Unknown, Dose: 1 dose per animal, Frequency: 1 per day • Reactions: Pinnal ulcer • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-052998
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 8.00 Year
  • Weight: 4.627 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Injection
  • Dose: 1 dose per animal
  • Frequency: 1 per day
Reactions Reported:
Pinnal ulcer
Outcomes: Recovered/Normal

Dog, Cattle Dog - Flanders (Bouvier), Female, 10 year, 61.2 kilogram • Drug: MSK, Subcutaneous, Dose: 1 dose per animal • Reactions: Inappropriate urination, Pollakiuria, Blood in urine, Unclassifiable adverse event, Female reproductive tract disorder NOS… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-050192
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 10.00 Year
  • Weight: 61.200 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Dose: 1 dose per animal
Reactions Reported:
Inappropriate urination Pollakiuria Blood in urine Unclassifiable adverse event Female reproductive tract disorder NOS Itching Tiredness (lethargy) Increased weight
Outcomes: Outcome Unknown

Dog, ['Terrier - Yorkshire', 'Dog (unknown)'], Female, 11 year, 4.1 kilogram • Drug: MSK, Injection, Subcutaneous • Reactions: Loss of hearing • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-049475
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 11.00 Year
  • Weight: 4.100 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Injection
Reactions Reported:
Loss of hearing
Outcomes: Recovered/Normal

Dog, Terrier - Rat, Female, 6 year, 9.1 kilogram • Drug: MSK, Injection, Subcutaneous • Reactions: Application site reddening, Application site itching • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-051027
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 6.00 Year
  • Weight: 9.100 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Injection
Reactions Reported:
Application site reddening Application site itching
Outcomes: Recovered/Normal

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

Refrigerate and protect from light; do not freeze.

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