Skip to main content

Need urgent help? Start triage first, then route to emergency care.

Start symptom intake Emergency vets near you

Meds A-Z

Afoxolaner

Detailed information about Afoxolaner

Official label facts Owner quick guide first Marketing clearly labeled
Talk to a Vet / Find a Vet Near You Start Symptom Intake
Showing simplified owner view. Switch to Vet View for full technical detail.

Pet Owner Quick Guide

Start here: what this medicine is for, what it does, and when it's usually needed.

Usually used for:

For the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of adult hookworm ( Ancylostoma caninum , Ancylostoma braziliense , and Uncinaria stenocephala ) and roundworm ( Tox...

What it does:

Kills adult fleas and is indicated for the treatment and prevention of flea infestations ( Ctenocephalides felis ), and the treatment and control of Ixodes scapularis (black-legged tick), Dermacentor variabilis (American...

When it's needed:

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Call your vet sooner if you notice:

  • Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Commonly reported reactions:

  • (1 reports)
  • (1 reports)
  • (1 reports)

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Talk to a Vet / Find a Vet Near You
Image coming soon
Afoxolaner

Afoxolaner

Drug type: Generic ingredient • Branded profile • FDA branded products available

Species: Both

Manufacturer: MSK

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: MSK
Form: Chewable Tablets
Identifiers:
NADA: 141406 NADA: 141554 NDC Package: 0010-2405-01 NDC Package: 0010-2405-02 NDC Package: 0010-2405-03 NDC Package: 0010-2407-01 NDC Package: 0010-2407-02 NDC Package: 0010-2407-03 NDC Package: 0010-2409-01 NDC Package: 0010-2409-02 NDC Package: 0010-2409-03 NDC Package: 0010-2411-01 NDC Package: 0010-2411-02 NDC Package: 0010-2411-03 NDC Package: 0010-4120-01 NDC Package: 0010-4120-02 NDC Package: 0010-4120-03 NDC Package: 0010-4121-01 NDC Package: 0010-4121-02 NDC Package: 0010-4121-03
Source metadata:

Warnings / Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

  • High: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
13
Serious reports
1
Species represented
2
Most Reported Reactions
Reaction Cases Species Serious cases
1 Cat 1
1 Cat 0
1 Cat 0
1 Dog 0
1 Dog 0
1 Dog 0
1 Dog 0
1 Dog 0

Species coverage: Cat (19) Dog (13)

View detailed reaction table
Reaction Species Seriousness Frequency Reports
Cat Non-serious - 1
Cat Non-serious - 1
Cat Serious - 1
Dog Non-serious - 1
Cat Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Cat Non-serious - 1
Cat Non-serious - 1
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Source metadata:

Storage & Handling

No storage/handling guidance is linked yet.

Source metadata: No source yet.

Documents

Official label facts are separated from secondary summaries.

Official documents: 12 • Secondary summaries: 0

Official label facts
Secondary summaries

No source yet.

Source metadata:

Promotional Materials (Marketing)

This content is marketing material and not clinical guidance.

No marketing assets are linked yet.

No source yet.

Source metadata: No source yet.
Talk to a Vet / Find a Vet Near You
Technical appendix (vet reference)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 16, 2026, 11:02 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 12, 2026, 10:42 PM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: NexGard® NexGard® PLUS
Case-reported brands (openFDA): MSK
Catalog species: Both • FDA-labeled species: Dog
Rx/OTC: RX
Form/route: Chewable Tablets • Oral
Applications: NADA 141-554 • NADA 141-406
Documents: 10 (FOI: 10) • SPL: 2 • Label highlights • Official documents
Safety (openFDA)
Top reactions: Dog 56 • Cat 20 • View
Case summaries: 11 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Explore
Linked using: Fda_Label (0.95), Fda_Label (0.95)
Diagnosis Codes
ICD10_CM: B74.8 ICD10_CM: B88.1
Other filariases

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Federal law restricts this drug to use by or on the order of a licensed veterinarian. (Contraindication, High)
Top reaction signals
Administration error NOS (1) Ataxia (1) Death (1) Decreased appetite (1) Hiding (1) Hives (see also Skin) (1) Itching (1) Lack of efficacy (endoparasite) - hookworm (1) Lack of efficacy (endoparasite) - tapeworm (1) Lack of efficacy (protozoa) - Giardia (1) Lethargy (see also Central nervous system depression in Neurological) (1) Reluctant to move (1) Shaking (1) Administration error NOS (reports: 1, since 2025-08-16) (0) Administration error NOS (reports: 1, since 2025-08-17) (0) Administration error NOS (reports: 1, since 2025-08-18) (0)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
NADA: 141406 NADA: 141554 NDC Package: 0010-2405-01 NDC Package: 0010-2405-02 NDC Package: 0010-2405-03 NDC Package: 0010-2407-01 NDC Package: 0010-2407-02 NDC Package: 0010-2407-03 NDC Package: 0010-2409-01 NDC Package: 0010-2409-02 NDC Package: 0010-2409-03 NDC Package: 0010-2411-01 NDC Package: 0010-2411-02 NDC Package: 0010-2411-03 NDC Package: 0010-4120-01 NDC Package: 0010-4120-02 NDC Package: 0010-4120-03 NDC Package: 0010-4121-01 NDC Package: 0010-4121-02 NDC Package: 0010-4121-03 NDC Package: 0010-4260-01 NDC Package: 0010-4260-02 NDC Package: 0010-4260-03 NDC Package: 0010-4261-01
Package NDC Product NDC Form / Route Status
0010-2405-01 0010 -
0010-2405-02 0010 -
0010-2405-03 0010 -
0010-2407-01 0010 -
0010-2407-02 0010 -
0010-2407-03 0010 -
0010-2409-01 0010 -
0010-2409-02 0010 -
0010-2409-03 0010 -
0010-2411-01 0010 -
0010-2411-02 0010 -
0010-2411-03 0010 -
0010-4120-01 0010 -
0010-4120-02 0010 -
0010-4120-03 0010 -
0010-4121-01 0010 -
0010-4121-02 0010 -
0010-4121-03 0010 -
0010-4260-01 0010 -
0010-4260-02 0010 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

Data Sources & Revision History

Every non-trivial field is expected to include provenance and update timestamps.

Official 13 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. (Official, 2026-02-12)
  • side_effects: Top reported reactions (openFDA): Vomiting, Lack of efficacy (ectoparasite) - tick NOS, Lethargy (see also Central nervous system depression in 'Neurological')… (Official, 2026-02-12)
  • usage: Kills adult fleas and is indicated for the treatment and prevention of flea infestations ( Ctenocephalides felis ), and the treatment and control of Ixodes sca… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
NexGard® PLUS
RX
Afoxolaner Moxidectin Pyrantel Pamoate
Chewable Tablets • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA, Inc. NADA 141-554 Approved Feb 2, 2026
NexGard®
RX
Afoxolaner
Chewable Tablets • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA, Inc. NADA 141-406 Approved Jan 14, 2025

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
Each chewable tablet contains 9.375 mg afoxolaner, 45 mcg moxidectin, and 18.75 mg pyrantel; 18.75 mg afoxolaner, 90 mcg moxidectin, and 37.5 mg pyrantel; 37.5 mg afoxolaner, 180 mcg moxidectin, and 75 mg pyrantel; 75 mg afoxolaner, 360 mcg moxidectin, and 150 mg pyrantel; or 150 mg afoxolaner, 720 mcg moxidectin, and 300 mg pyrantel.
Dogs
Indication

For the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of adult hookworm (Ancylostoma caninum, Ancylostoma braziliense, and Uncinaria stenocephala) and roundworm (Toxocara canis and Toxascaris leonina) infections. Kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of Ixodes scapularis (blacklegged tick), Rhipicephalus sanguineus (brown dog tick), Dermacentor variabilis (American dog tick), Amblyomma americanum (lone star tick), Amblyomma maculatum (Gulf Coast tick), and Haemaphysalis longicornis (longhorned tick) infestations for one month in dogs and puppies eight weeks of age and older, weighing four pounds of body weight or greater. For the prevention of Borrelia burgdorferi infections as a direct result of killing Ixodes scapularis vector ticks.

Dosage

Administer orally once a month at the minimum dose of 1.14 mg/lb (2.5 mg/kg) afoxolaner, 5.45 mcg/lb (12 mcg/kg) moxidectin, and 2.27 mg/lb (5.0 mg/kg) pyrantel (as pamoate salt). For heartworm disease prevention, give once monthly for at least six months after last exposure to mosquitoes.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
Each chewable contains 11.3 mg, 28.3 mg, 68 mg, or 136 mg afoxolaner.
Dogs (Dogs and Puppies 8 Weeks of Age and Older)
Indication

Kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick), Amblyomma americanum (lone star tick), Rhipicephalus sanguineus (brown dog tick), and Haemaphysalis longicornis (longhorned tick) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for 1 month; and for the prevention of Borrelia burgdorferi infections as a direct result of killing Ixodes scapularis vector ticks.

Dosage

NexGard® is given once a month at the minimum dosage of 1.14 mg/lb (2.5 mg/kg).

Limitations

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Official Documents (FDA)

Direct links to FDA-hosted PDFs and SPL packages (when available).

Documents
  • Summary

    This supplement provides for the addition of the indication for the treatment and control of Amblyomma maculatum (Gulf Coast tick) infestations for one month in dogs and puppies eight weeks of age and older, weighing four pounds of body weight or greater.

  • Summary

    This supplement provides for the addition of the indication for the prevention of Borrelia burgdorferi infections as a direct result of killing Ixodes scapularis vector ticks.

  • Summary

    This supplement provides for the addition of the indication for the treatment and control of Haemaphysalis longicornis (longhorned tick) infestations in dogs and puppies eight weeks of age and older, weighing four pounds of body weight or greater, for one month. This supplement also provides for the addition of label language regarding the results of a second flea field study and improvement of erythema, alopecia, papules, scales, crusts, and excoriation in dogs with flea infestations and signs of Flea Allergy Dermatitis following treatment with afoxolaner alone, as a direct result of eliminating fleas.

  • Summary

    For the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of adult hookworm (Ancylostoma caninum, Ancylostoma braziliense, and Uncinaria stenocephala) and roundworm (Toxocara canis and Toxascaris leonina) infections. Kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of Ixodes scapularis (black-legged tick), Rhipicephalus sanguineus (brown dog tick), Dermacentor variabilis (American dog tick), and Amblyomma americanum (lone star tick) infestations for one month in dogs and puppies eight weeks of age and older, weighing four pounds of body weight or greater.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    This supplement provides for a new modified NexGard® formulation.

    This supplement provides for the addition of the indication for the treatment and control of Haemaphysalis longicornis (longhorned tick) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for one month.

    This supplement also provides for the addition of label language regarding the improvement of erythema, alopecia, papules, scales, crusts, and excoriation in dogs with flea infestations and signs of Flea Allergy Dermatitis following treatment with NexGard®, as a direct result of eliminating fleas.

  • Summary

    This supplement provides for the addition of the indication for the prevention of Borrelia burgdorferi infections as a direct result of killing Ixodes scapularis vector ticks.

  • Summary
    The effect of the supplement is to provide for the treatment and control of Brown dog tick ( Rhipicephalus sanguineus) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for one month.
  • Summary
    This supplement provides for the treatment and control of Black-legged tick (Ixodes scapularis) and Lone Star tick (Amblyomma americanum) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for one month.
  • Summary
    The effect of the supplement is to add language to the Effectiveness section of the package insert from the flea speed of kill study.
  • Summary
    For the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of American dog tick (Dermacentor variabilis) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for 1 month.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Usage

Kills adult fleas and is indicated for the treatment and prevention of flea infestations ( Ctenocephalides felis ), and the treatment and control of Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick), Amblyomma americanum (lone star tick), Rhipicephalus sanguineus (brown dog tick), and Haemaphysalis longicornis (longhorned tick) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for 1 month; and for the prevention of Borrelia burgdorferi infections as a direct result of killing Ixodes scapularis vector ticks. For the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of adult hookworm ( Ancylostoma caninum , Ancylostoma braziliense , and Uncinaria stenocephala ) and roundworm ( Toxocara canis and Toxascaris leonina ) infections. Kills adult fleas and is indicated for the treatment and prevention of flea infestations ( Ctenocephalides felis ) and the treatment and control of Ixodes scapularis (blacklegged tick), Rhipicephalus sanguineus (brown dog tick), Dermacentor variabilis (American dog tick), Amblyomma americanum (lone star tick), Amblyomma maculatum (Gulf Coast tick), and Haemaphysalis longicornis (longhorned tick) infestations for one month in dogs and puppies eight weeks of age and older, weighing four pounds of body weight or greater. For the prevention of Borrelia burgdorferi infections as a direct result of killing Ixodes scapularis vector ticks.

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Side Effects

No approved side-effect narrative is linked yet.

openFDA reaction signals are available for Dog 56 and Cat 20 (view top reported reactions).

Top Reported Reactions (openFDA)

Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).

Dog
Digestive
Vomiting (10330) Diarrhea (3744) Vomiting (30) Vomiting (30) Vomiting (30) Vomiting (30) Vomiting (28) Vomiting (26) Diarrhea (17) Diarrhea (17) Diarrhea (17) Diarrhea (17) Diarrhea (13) Diarrhea (12)
Neurologic
Tiredness (lethargy) (4085) Seizure NOS (3227) Seizure NOS (22) Seizure NOS (22) Seizure NOS (22) Seizure NOS (22) Seizure NOS (21) Seizure NOS (21) Tiredness (lethargy) (18) Tiredness (lethargy) (18) Tiredness (lethargy) (18) Tiredness (lethargy) (18) Tiredness (lethargy) (18) Tiredness (lethargy) (17)
Effectiveness
Lack of efficacy (ectoparasite) - tick NOS (4321) Lack of efficacy (ectoparasite) - flea (3534) Lack of efficacy (bacteria) - Borrelia (2886) Lack of efficacy (bacteria) - NOS (2592) Lack of efficacy (bacteria) - Borrelia (41) Lack of efficacy (bacteria) - Borrelia (41) Lack of efficacy (bacteria) - Borrelia (41) Lack of efficacy (bacteria) - Borrelia (41) Lack of efficacy (bacteria) - Borrelia (36) Lack of efficacy (ectoparasite) - tick NOS (36) Lack of efficacy (ectoparasite) - tick NOS (36) Lack of efficacy (ectoparasite) - tick NOS (36) Lack of efficacy (bacteria) - Borrelia (35) Lack of efficacy (ectoparasite) - tick NOS (35) Lack of efficacy (ectoparasite) - tick NOS (28) Lack of efficacy (ectoparasite) - tick NOS (26) Lack of efficacy (ectoparasite) - flea (18) Lack of efficacy (ectoparasite) - flea (18) Lack of efficacy (ectoparasite) - flea (18) Lack of efficacy (ectoparasite) - flea (18) Lack of efficacy (ectoparasite) - flea (17) Lack of efficacy (ectoparasite) - flea (17) Lack of efficacy (bacteria) - Anaplasma (16) Lack of efficacy (bacteria) - Anaplasma (16) Lack of efficacy (bacteria) - Anaplasma (16) Lack of efficacy (bacteria) - Anaplasma (16)
Other
Not eating (15) Not eating (15)
Cat
Digestive
Vomiting (11)
Neurologic
Tiredness (lethargy) (5)
Behavior
Behavioral disorder (unspecified) (4)
Other
Administration error NOS (8) Hyperactivity (5) Panting (5) Inappetence (4) Not eating (4) Administration error NOS (1) Administration error NOS (1) Administration error NOS (1) Administration error NOS (1) Administration error NOS (1) Administration error NOS (1) Hiding (1) Hiding (1) Hiding (1) Hiding (1) Hiding (1) Hiding (1)

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Retriever - Golden, Unknown, 1 year, 26.76 kilogram • Drug: MSK, Unknown • Reactions: Lack of efficacy (endoparasite) - tapeworm • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-056118
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Unknown
  • Age: 1.00 Year
  • Weight: 26.760 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Lack of efficacy (endoparasite) - tapeworm
Outcomes: Outcome Unknown

Dog, Retriever - Golden, Unknown, 1 year, 20.86 kilogram • Drug: MSK, Unknown • Reactions: Lack of efficacy (endoparasite) - tapeworm • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-056116
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Unknown
  • Age: 1.00 Year
  • Weight: 20.860 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Lack of efficacy (endoparasite) - tapeworm
Outcomes: Outcome Unknown

Dog, Crossbred Canine/dog, Female, 12 year, 3.538 kilogram • Drug: MSK, Tablet, chewable, Unknown • Reactions: Hives, Tiredness (lethargy), Decreased appetite • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-055457
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Female
  • Age: 12.00 Year
  • Weight: 3.538 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Tablet, chewable
Reactions Reported:
Hives Tiredness (lethargy) Decreased appetite
Outcomes: Recovered/Normal

Dog, Crossbred Canine/dog, Male, 8 year, 15.91 kilogram • Drug: MSK, Oral • Reactions: Lack of efficacy (endoparasite) - hookworm, Itching • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-055786
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 8.00 Year
  • Weight: 15.910 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
Reactions Reported:
Lack of efficacy (endoparasite) - hookworm Itching
Outcomes: Outcome Unknown

Dog, Retriever - Labrador, Male, 7 year, 33.112 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per animal • Reactions: Lack of efficacy (endoparasite) - tapeworm • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-055716
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 7.00 Year
  • Weight: 33.112 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per animal
Reactions Reported:
Lack of efficacy (endoparasite) - tapeworm
Outcomes: Outcome Unknown

Dog, Doberman Pinscher, Male, 5 month, 21.863 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 dose per animal • Reactions: Lack of efficacy (endoparasite) - hookworm, Lack of efficacy (protozoa) - Giardia • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055419
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 5.00 Month
  • Weight: 21.863 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 dose per animal
Reactions Reported:
Lack of efficacy (endoparasite) - hookworm Lack of efficacy (protozoa) - Giardia
Outcomes: Ongoing

Cat, Domestic Longhair, Female, 8 year, 6.577 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 0.50 tablet per animal • Reactions: Hiding, Administration error NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-050688
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 8.00 Year
  • Weight: 6.577 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 0.50 tablet per animal
Reactions Reported:
Hiding Administration error NOS
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Male, 4 month, 2.404 kilogram • Drug: MSK, Tablet, chewable, Oral • Reactions: Shaking • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-043460
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 4.00 Month
  • Weight: 2.404 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
Reactions Reported:
Shaking
Outcomes: Outcome Unknown

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

Share Your Thoughts

Let others know your experience or advice regarding this medication.

This medication has not been reviewed by a veterinarian yet.