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Fenbendazole

Detailed information about Fenbendazole

Official label facts Owner quick guide first Marketing clearly labeled
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Pet Owner Quick Guide

Start here: what this medicine is for, what it does, and when it's usually needed.

Usually used for:

For the treatment and control of: Lungworms : Adult Dictyocaulus viviparu s; Stomach worms : Adult brown stomach worms ( Ostertagia ostertagi ), Adult and fourth stage larvae barberpole worms ( Haemonchus contortus & H.

What it does:

For the treatment and control of large strongyles ( Strongylus edentatus , S. equinus , S. vulgaris , Triodontophorus spp.),small strongyles ( Cyathostomum spp., Cylicocyclus spp., Cylicostephanus spp., Cylicodontophorus...

When it's needed:

Sprinkle the appropriate amount of drug on a small amount of the usual grain ration. Prepare for each horse individually. Withholding feed or water is not necessary. Retreat in 6 to 8 weeks if required. Do not use in hor...

Call your vet sooner if you notice:

  • Sprinkle the appropriate amount of drug on a small amount of the usual grain ration. Prepare for each horse individually. Withholding feed or water is not necessary. Retreat in 6 to 8 weeks if required. Do not use in horses intended for food. Consult your veterinarian assistance in the diagnosis, treatment, and control of parasitism. Do not use in horses intended for human consumption. Consult your veterinarian for assistance in the diagnosis, treatment and control of parasitism. Mix the appropriate amount of drug with a small amount of the usual food. Dry dog food may require slight moistening to facilitate mixing. Medicated food must be fully consumed.

Commonly reported reactions:

  • (2 reports)
  • (1 reports)
  • (1 reports)

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
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Fenbendazole

Fenbendazole

Drug type: Generic ingredient • Branded profile • FDA branded products available

Species: Both

Manufacturer: Intervet, Inc.

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Intervet, Inc.
Form: Liquid (Suspension), Medicated Feed, Medicated Feed Block, Oral Suspension, Paste, Top Dressing In Feed
Identifiers:
ANADA: 200831 NADA: 104494 NADA: 111278 NADA: 120648 NADA: 121473 NADA: 128620 NADA: 131675 NADA: 132872 NADA: 136116 NADA: 139189 NADA: 140954 NADA: 141144 NADA: 141449 NDC Package: 0061-1433-01 NDC Package: 0061-1433-02 NDC Package: 0061-1433-03 NDC Package: 43457-650-25 NDC Package: 49452-3035-1 NDC Package: 49452-3035-2 NDC Package: 49452-3035-3
Source metadata:

Warnings / Contraindications

Sprinkle the appropriate amount of drug on a small amount of the usual grain ration. Prepare for each horse individually. Withholding feed or water is not necessary. Retreat in 6 to 8 weeks if required. Do not use in horses intended for food. Consult your veterinarian assistance in the diagnosis, treatment, and control of parasitism. Do not use in horses intended for human consumption. Consult your veterinarian for assistance in the diagnosis, treatment and control of parasitism. Mix the appropriate amount of drug with a small amount of the usual food. Dry dog food may require slight moistening to facilitate mixing. Medicated food must be fully consumed.

  • High: Sprinkle the appropriate amount of drug on a small amount of the usual grain ration. Prepare for each horse individually. Withholding feed or water is not necessary. Retreat in 6 to 8 weeks if required. Do not use in horses intended for food. Consult your veterinarian assistance in the diagnosis, treatment, and control of parasitism. Do not use in horses intended for human consumption. Consult your veterinarian for assistance in the diagnosis, treatment and control of parasitism. Mix the appropriate amount of drug with a small amount of the usual food. Dry dog food may require slight moistening to facilitate mixing. Medicated food must be fully consumed.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
24
Serious reports
20
Species represented
2
Most Reported Reactions
Reaction Cases Species Serious cases
2 Cat, Dog 1
1 Cat 1
1 Cat 1
1 Cat 1
1 Cat 1
1 Cat 1
1 Cat 1
1 Cat 1

Species coverage: Cat (26) Dog (6)

View detailed reaction table
Reaction Species Seriousness Frequency Reports
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Dog Non-serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Serious - 1
Cat Non-serious - 1
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Cat Unknown - -
Dog Unknown - -
Dog Unknown - -
Dog Unknown - -
Source metadata:

Storage & Handling

No storage/handling guidance is linked yet.

Source metadata: No source yet.

Documents

Official label facts are separated from secondary summaries.

Official documents: 57 • Secondary summaries: 0

Official label facts
Secondary summaries

No source yet.

Source metadata:

Promotional Materials (Marketing)

This content is marketing material and not clinical guidance.

No marketing assets are linked yet.

No source yet.

Source metadata: No source yet.
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Technical appendix (vet reference)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 16, 2026, 11:02 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:20 AM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: BMD® / Safe-Guard® Defendazole™ Panacur® C (OTC) Safe-Guard® Canine (OTC) Panacur® Granules 22.2% (Rx) Panacur® Granules 22.2% Panacur® Suspension 10% Purina® Worm-A-Rest Litter Pack SAFE-GUARD® plus LINCOMIX® Safe-Guard® Safe-Guard® AquaSol Safe-Guard® Panacur® safe-guard® panacur®
Case-reported brands (openFDA): MSK
Catalog species: Both • FDA-labeled species: Beef, Beef And Dairy, Boars, Breeders, Broilers, Dairy, Dog, Finishing, Gilts, Growing, Horse, Layers, No Use Class Stated Or Implied, No use class stated or implied, Non-Lactating, Pony, Pregnant sows, Replacements, Swine, Up to 250 pounds, Wild Animals, Zoo Animals
Rx/OTC: OTC, RX, VFD
Form/route: Liquid (Suspension), Medicated Feed, Medicated Feed Block, Oral Suspension, Paste, Top Dressing In Feed, Type A Medicated Article • Oral
Applications: ANADA 200-831 • NADA 141-144 • NADA 131-675 • NADA 132-872 • NADA 140-954 • NADA 128-620 • NADA 104-494 • NADA 120-648 • NADA 121-473 • NADA 139-189 • NADA 141-449 • NADA 136-116 • NADA 111-278
Documents: 40 (FOI: 26) • SPL: 17 • Label highlights • Official documents
Safety (openFDA)
Top reactions: Dog 56 • Cat 20 • View
Case summaries: 10 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Explore
Linked using: Fda_Label (0.95), Fda_Label (0.95)
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Sprinkle the appropriate amount of drug on a small amount of the usual grain ration. Prepare for each horse individually. Withholding feed or water is not necessary. Retreat in 6 to 8 weeks if required. Do not use in horses intended for food. Consult your veterinarian assistance in the diagnosis, treatment, and control of parasitism. Do not use in horses intended for human consumption. Consult your veterinarian for assistance in the diagnosis, treatment and control of parasitism. Mix the appropriate amount of drug with a small amount of the usual food. Dry dog food may require slight moistening to facilitate mixing. Medicated food must be fully consumed. (Contraindication, High)
Top reaction signals
Anaemia NOS (1) Death (1) Death by euthanasia (1) Decreased blood urea nitrogen (BUN) or creatinine (1) Digestive tract neoplasm NOS (1) Dyspnoea (1) Elevated amylase (1) Elevated globulins (1) Elevated renal parameters (1) Eye neoplasm NOS (1) Hind limb paralysis (1) Injection site complication NOS (1) Lack of efficacy (endoparasite) - heartworm (1) Lack of efficacy (endoparasite) - hookworm (1) Lack of efficacy - NOS (1) Lack of efficacy - NOS (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
ANADA: 200831 NADA: 104494 NADA: 111278 NADA: 120648 NADA: 121473 NADA: 128620 NADA: 131675 NADA: 132872 NADA: 136116 NADA: 139189 NADA: 140954 NADA: 141144 NADA: 141449 NDC Package: 0061-1433-01 NDC Package: 0061-1433-02 NDC Package: 0061-1433-03 NDC Package: 43457-650-25 NDC Package: 49452-3035-1 NDC Package: 49452-3035-2 NDC Package: 49452-3035-3 NDC Package: 49452-3035-4 NDC Package: 49452-3035-5 NDC Package: 49452-3035-6 NDC Package: 55529-165-06
Package NDC Product NDC Form / Route Status
0061-1433-01 0061 -
0061-1433-02 0061 -
0061-1433-03 0061 -
43457-650-25 43457 -
49452-3035-1 49452 -
49452-3035-2 49452 -
49452-3035-3 49452 -
49452-3035-4 49452 -
49452-3035-5 49452 -
49452-3035-6 49452 -
55529-165-06 55529 -
55529-165-08 55529 -
57926-081-44 57926 -
57926-081-48 57926 -
57926-083-44 57926 -
57926-084-46 57926 -
57926-085-47 57926 -
57926-086-01 57926 -
57926-087-01 57926 -
57926-088-01 57926 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

Data Sources & Revision History

Every non-trivial field is expected to include provenance and update timestamps.

Official 29 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: Sprinkle the appropriate amount of drug on a small amount of the usual grain ration. Prepare for each horse individually. Withholding feed or water is not nece… (Official, 2026-02-12)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy (endoparasite) - hookworm, Vomiting, INEFFECTIVE, HOOKS, Diarrhoea, Other abnormal test result NOS, Lack of … (Official, 2026-02-12)
  • usage: For the treatment and control of large strongyles ( Strongylus edentatus , S. equinus , S. vulgaris , Triodontophorus spp.),small strongyles ( Cyathostomum spp… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Defendazole™
OTC
Fenbendazole
Oral Suspension • Oral
Label highlights
Official documents
Norbrook Laboratories, Ltd. ANADA 200-831 Approved Feb 2, 2026
BMD® / Safe-Guard®
OTC
Bacitracin methylenedisalicylate Fenbendazole
Medicated Feed • Oral
Label highlights
Official documents
Phibro Animal Health Corp. NADA 141-144 Approved Nov 12, 2024
Safe-Guard®
OTC
Fenbendazole
Type A Medicated Article • Oral
Label highlights
Official documents
Intervet, Inc. NADA 131-675 Approved Jun 3, 2024
Safe-Guard®
OTC
Fenbendazole
Paste • Oral
Label highlights
Official documents
Intervet, Inc. NADA 132-872 Approved Oct 12, 2023
SAFE-GUARD® plus LINCOMIX®
VFD
Fenbendazole Lincomycin
Type A Medicated Article • Oral
Label highlights
Official documents
Intervet, Inc. NADA 140-954 W Aug 25, 2023
Safe-Guard® Panacur®
OTC
Fenbendazole
Liquid (Suspension) • Oral
Label highlights
Official documents
Intervet, Inc. NADA 128-620 Approved Jun 6, 2022
Panacur® Suspension 10%
RX
Fenbendazole
Liquid (Suspension) • Oral
Label highlights
Official documents
Intervet, Inc. NADA 104-494 Approved Jun 2, 2022
safe-guard® panacur®
OTC
Fenbendazole
Paste • Oral
Label highlights
Official documents
Intervet, Inc. NADA 120-648 Approved Jan 25, 2022
Panacur® C (OTC) Safe-Guard® Canine (OTC) Panacur® Granules 22.2% (Rx)
OTC
Fenbendazole
Top Dressing In Feed • Oral
Label highlights
Official documents
Intervet, Inc. NADA 121-473 Approved May 6, 2021
Safe-Guard®
OTC
Fenbendazole
Medicated Feed Block • Oral
Label highlights
Official documents
Intervet, Inc. NADA 139-189 Approved May 3, 2021
Safe-Guard® AquaSol
OTC
Fenbendazole
Oral Suspension • Oral
Label highlights
Official documents
Intervet, Inc. NADA 141-449 Approved Apr 12, 2021
Purina® Worm-A-Rest Litter Pack
OTC
Fenbendazole
Medicated Feed • Oral
Label highlights
Official documents
Virbac AH, Inc. NADA 136-116 W Nov 2, 2018
Panacur® Granules 22.2%
OTC
Fenbendazole
Top Dressing In Feed • Oral
Label highlights
Official documents
Intervet, Inc. NADA 111-278 Approved Jun 1, 2016

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Beef And Dairy
Composition / specifications
100 mg/mL (10%)
Beef and Dairy Cattle
Indication

For the treatment and control of:
Lungworms: Adult Dictyocaulus viviparus;
Stomach worms: Adult brown stomach worms (Ostertagia ostertagi), Adult and fourth stage larvae barberpole worms (Haemonchus contortus & H. placei), and Adult and fourth stage larvae small stomach worms (Trichostrongylus axei);
Intestinal worms (Adult and fourth stage larvae): hookworms (Bunostomum phlebotomum), thread-necked intestinal worms (Nematodirus helvetianus), small intestinal worms (Cooperia punctata & C. oncophora), bankrupt worms (Trichostrongylus colubriformis), and nodular worms (Oesophagostomum radiatum).

Dosage

2.3 mg/lb (5 mg/kg) body weight

Limitations
Goats
Indication

For the treatment and control of:
Stomach worms (adults): Haemonchus contortus and Teladorsagia circumcincta.

Dosage

2.3 mg/lb (5 mg/kg) body weight

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Finishing • Growing • Pregnant sows
Composition / specifications
Bacitracin methylene disalicylate: Type A medicated article in concentrations of 10, 25, 30, 40, 50, 60, and 75 grams bacitracin activity per pound.
Fenbendazole: Type A medicated article in concentrations of 40, 80, and 200 grams fenbendazole activity per kilogram.
Swine (Pregnant Sows)
Indication
For the removal of: adult stage lungworms (Metastrongylus apri and M. pudendotectus); adult and larvae (L3, 4 stages-liver, lung, intestinal forms) large roundworms (Ascaris suum); adult stage nodular worms (Oesophagostomum dentatum, O. quadrispinulatum); small stomach worms (Hyostrongylus rubidus); adult and larvae (L2, 3, 4 stages-intestinal mucosal forms) whipworms (Trichuris suis; adult and larvae kidney worms (Stephanurus dentatus). For control of clostridial enteritis in suckling pigs caused by Clostridium perfringens.
Dosage
Fenbendazole, 10 to 300 grams per ton, and bacitracin methylene disalicylate, 250 grams per ton.
Limitations
Feed as sole ration. Diagnosis of clostridial enteritis should be confirmed by a veterinarian when results are not satisfactory. Under conditions of continued exposure to parasites, retreatment may be needed after 4 to 6 weeks. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.
Swine (Growing and Finishing)
Indication
For the removal of: adult stage lungworms (Metastrongylus apri and M. pudendotectus); adult and larvae (L3, 4 stages-liver, lung, intestinal forms) large roundworms (Ascaris suum); adult stage nodular worms (Oesophagostomum dentatum, O. quadrispinulatum); small stomach worms (Hyostrongylus rubidus); adult and larvae (L2, 3, 4 stages-intestinal mucosal forms) whipworms (Trichuris suis; adult and larvae kidney worms (Stephanurus dentatus). For increased rate of weight gain and improved feed efficiency.
Dosage
Fenbendazole, 10 to 300 grams per ton (to provide 9 milligrams per kilogram body weight), and bacitracin methylene disalicylate, 10 to 30 grams per ton.
Limitations
Feed as sole ration. Under conditions of continued exposure to parasites, retreatment may be needed after 4 to 6 weeks. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.
Indication
For the removal of: adult stage lungworms (Metastrongylus apri and M. pudendotectus); adult and larvae (L3, 4 stages-liver, lung, intestinal forms) large roundworms (Ascaris suum); adult stage nodular worms (Oesophagostomum dentatum, O. quadrispinulatum); small stomach worms (Hyostrongylus rubidus); adult and larvae (L2, 3, 4 stages-intestinal mucosal forms) whipworms (Trichuris suis; adult and larvae kidney worms (Stephanurus dentatus). For control of swine dysentery associated with Treponema hyodysenteriae on premises with a history of swine dysentery, but where signs of disease have not yet occurred; or following an approved treatment of the disease condition.
Dosage
Fenbendazole, 10 to 300 grams per ton, and bacitracin methylene disalicylate, 250 grams per ton.
Limitations
Feed as sole ration. Not for use in growing and finishing swine that weigh more than 250 pounds. Diagnosis of swine dysentery should be confirmed by a veterinarian when results are not satisfactory. Under conditions of continued exposure to parasites, retreatment may be needed after 4 to 6 weeks. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.

FDA page: Open in Animal Drugs @ FDA

Species: Gilts • Growing • Pregnant sows • Boars • Beef And Dairy • No Use Class Stated Or Implied • Growing • Zoo Animals • Swine, Feral • Wild Animals
Composition / specifications
Type A medicated articles conatianing 4 percent (18.1 grams per pound), 8 percent (36.2 grams per pound), and 20 percent (90.7 grams per pound) fenbendazole.
Bighorn sheep
Indication

For the treatment and control of: Lungworms (Protostrongylus spp.).

Dosage

10 mg fenbendazole/kg body weight/day x 3 days of treatment

Limitations
Feral Swine
Indication

For the treatment and control of: kidney worms (Stephanurus dentatus), roundworms (Ascaris suum), and nodular worms (Oesophagostomum dentatum).

Dosage

3 mg fenbendazole/kg body weight/day x 3 days of treatment

Limitations
Wildlife and Zoo Ruminants (Subfamily Antilopinae, Hippotraginae, and Caprinae)
Indication

For the treatment and control of: Stomach worms: small stomach worms (Trichostrongylus spp.), barberpole worms (Haemonchus spp.); Intestinal worms: thread-necked intestinal worms (Nematodirus spp.) and whipworms (Trichuris spp.)

Dosage

2.5 mg fenbendazole/kg body weight/day x 3 days of treatment

Limitations
Growing Turkeys
Indication

For the treatment and control of: Gastrointestinal worms: Roundworms, Adults and larvae (Ascaridia dissimilis); Cecal worms, Adults and larvae (Heterakis gallinarum), an important vector of Histomonas meleagridis (Blackhead).

Dosage

14.5 g fenbendazole/ton of feed, to be fed as the sole ration for 6 days

Limitations
Swine (Growing pigs, gilts, pregnant sows, and boars)
Indication

For the treatment and control of: Lungworms: Adult Metastrongylus apri, adult Metastrongylus pudendotectus; Gastrointestinal worms: Adult and larvae (L3, L4 stages, liver, lung, intestinal forms) large roundworms (Ascaris suum), Adult nodular worms (Oesophagostomum dentatum, O. quadrispinulatum), Adult small stomach worms (Hyostrongylus rubidus), Adult and larvae (L2, L3, L4 stages- intestinal mucosal forms) whipworms (Trichuris suis); and Kidney worms: Adult and larvae Stephanurus dentatus.

Dosage

9 mg fenbendazole per kg body weight (4.08 mg fenbendazole per pound) to be fed as the sole ration over a period of 3 to 12 days.

Limitations
Cattle (Dairy and Beef Cattle)
Indication

For the treatment and control of: Lungworms: Adult Dictyocaulus viviparus; Stomach worms: Adult brown stomach worms (Ostertagia ostertagi), Adult and fourth stage larvae barberpole worms (Haemonchus contortus), fourth stage larvae barberpole worms (H. placei), and Adult and fourth stage larvae small stomach worms (Trichostrongylus axei); Intestinal worms (Adult and fourth stage larvae): hookworms (Bunostomum phlebotomum), thread-necked intestinal worms (Nematodirus helvetianus), small intestinal worms (Cooperia punctata & C. oncophora), bankrupt worms (Trichostrongylus colubriformis), and nodular worms (Oesophagostomum radiatum)

Dosage

5 mg fenbendazole per kg body weight in a one (1) day treatment (2.27 mg fenbendazole per pound). Feed as the sole ration for one (1) day. Free-Choice Feeds: Type C free-choice medicated feed must be manufactured by a licensed feed mill according to an approved formula to provide a total of 5 mg per kg body weight fenbendazole over 3 to 6 days.

Limitations
Horses
Indication

For the treatment and control of: Large strongyles (Strongylus edentatus, S. equinus, S. vulgaris, Triodontophorus spp.), Small strongyles (Cyathostomum spp., Cylicocyclus spp., Cylicostephanus spp.), Pinworms (Oxyuris equi), and Ascarids (Parascaris equorum).

Dosage

For the control of large strongyles, small strongyles, and pinworms the recommended dose is 5 mg fenbendazole per kg body weight (2.27 mg fenbendazole per pound) in a one (1) day treatment. For the control of ascarids the recommended dose is 10 mg fenbendazole per kg body weight (4.54 mg fenbendazole per pound) in a one (1) day treatment.

Limitations
Wild quail
Indication

For the treatment and control of Gastrointestinal worms: Cecal worms, (Aulonocephalus spp.).

Dosage

90.7 g of fenbendazole/ton of Type C medicated feed, to be fed for 21 consecutive days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Beef • Dairy
Composition / specifications
The product is an aqueous paste containing 10 percent fenbendazole.
Beef and dairy cattle
Indication

For the treatment and control of: Lungworms: Adult Dictyocaulus viviparus; Stomach worms: Adult brown stomach worms (Ostertagia ostertagi), Adult and fourth stage larvae barberpole worms (Haemonchus contortus), fourth stage larvae barberpole worms (H. placei), and Adult and fourth stage larvae small stomach worms (Trichostrongylus axei); Intestinal worms (Adult and fourth stage larvae): hookworms (Bunostomum phlebotomum), thread-necked intestinal worms (Nematodirus helvetianus), small intestinal worms (Cooperia punctata & C. oncophora), bankrupt worms (Trichostrongylus colubriformis), and nodular worms (Oesophagostomum radiatum).

Dosage
Administer orally 5 milligrams per kilogram of body weight (2.3 milligrams per pound).
Limitations

Do not underdose. Ensure each animal receives a complete dose based on a current body weight. Underdosing may result in ineffective treatment, and encourage the development of parasite resistance. Consult a veterinarian for assistance in the diagnosis, treatment, and control of parasitism.

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied • Up to 250 pounds
Composition / specifications
Type A medicated articles containing 4, 8, or 20 percent (18.1, 36.2, or 90.7 grams per pound) fenbendazole. Type A medicated articles containing 20 or 50 grams per pound lincomycin.
Swine
Indication

For the removal of: Lungworms: Metastrongylus apri, metastrongylus pudendotectus; Gastrointestinal worms: adult and larvae (L3, L4 stages, liver, lung, intestinal forms) large round worm (Ascaris suum); nodular worms (Oesophagostomum dentatum, O. quadrispinulatum); small stomach worm (Hyostrongylus rubidus); Kidney worm: adult and larvae Stephanurus dentatus. For treatment of swine dysentery.

Dosage

10 to 80 grams fenbendazole and 100 grams lincomycin per ton Type C medicated feed

Limitations

Calculate the amount of THIS feed that the pigs to be treated should eat within 3 to 12 days to get a total dose of 9 mg of fenbendazole per kilogram body weight (4.08 mg fenbendazole per pound body weight). Feed as the sole feed the calculated amount. When it is fully consumed resume normal feeding. Do not slaughter swine for human consumption for 6 days following last treatment with lincomycin. Occasionally, swine fed lincomycin may, within the first 2 days after the onset of treatment, develop diarrhea and/or swelling of the anus. On rare occasions, some pigs may show reddening of the skin and irritable behavior. These conditions have been self-correcting within 5- 8 days without discontinuing the lincomycin treatment. Do not allow rabbits, hamsters, guinea pigs, horses or ruminants access to feeds containing lincomycin. Ingestion by these species may result in severe gastrointestinal effects. The effects of lincomycin on swine reproductive performance, pregnancy, and lactation have not been determined. Feeds containing lincomycin are not to be fed to swine that weigh more than 250 lb.

Indication

For the removal of: Lungworms: Metastrongylus apri, metastrongylus pudendotectus; Gastrointestinal worms: adult and larvae (L3, L4 stages, liver, lung, intestinal forms) large round worm (Ascaris suum); nodular worms (Oesophagostomum dentatum, O. quadrispinulatum); small stomach worm (Hyostrongylus rubidus); Kidney worm: adult and larvae Stephanurus dentatus. For the control of swine dysentery; for use in swine on premises with a history of swine dysentery, but where symptoms have not yet occurred.

Dosage

10 to 80 grams fenbendazole and 40 grams lincomycin per ton Type C medicated feed.

Limitations

Calculate the amount of THIS feed that the pigs to be treated should eat within 3 to 12 days to get a total dose of 9 mg of fenbendazole per kilogram body weight (4.08 mg fenbendazole per pound body weight). Feed as the sole feed thecalculated amount. When it is fully consumed resume normal feeding. Occasionally, swine fed lincomycin may, within the first 2 days after the onset of treatment, develop diarrhea and/or swelling of the anus. On rare occasions, some pigs may show reddening of the skin and irritable behavior. These conditions have been self-correcting within 5- 8 days without discontinuing the lincomycin treatment. Do not allow rabbits, hamsters, guinea pigs, horses or ruminants access to feeds containing lincomycin. Ingestion by these species may result in severe gastrointestinal effects. The effects of lincomycin on swine reproductive performance, pregnancy, and lactation have not been determined. Feeds containing lincomycin are not to be fed to swine that weigh more than 250 lb.

Indication

For the removal of: Lungworms: Metastrongylus apri, metastrongylus pudendotectus; Gastrointestinal worms: adult and larvae (L3, L4 stages, liver, lung, intestinal forms) large round worm (Ascaris suum); nodular worms (Oesophagostomum dentatum, O. quadrispinulatum); small stomach worm (Hyostrongylus rubidus); Kidney worm: adult and larvae Stephanurus dentatus. For reduction in the severity of swine mycoplasma pneumonia caused by Mycoplasma hyopneumoniae.

Dosage

10 to 80 grams fenbendazole and 200 grams lincomycin per ton Type C medicated feed.

Limitations

Calculate the amount of THIS feed that the pigs to be treated should eat within 3 to 12 days to get a total dose of 9 mg of fenbendazole per kilogram body weight (4.08 mg fenbendazole per pound body weight). Feed as the sole feed the calculated amount. When it is fully consumed resume normal feeding. Do not slaughter swine for human consumption for 6 days following last treatment with lincomycin. Occasionally, swine fed lincomycin may, within the first 2 days after the onset of treatment, develop diarrhea and/or swelling of the anus. On rare occasions, some pigs may show reddening of the skin and irritable behavior. These conditions have been self-correcting within 5- 8 days without discontinuing the lincomycin treatment. Do not allow rabbits, hamsters, guinea pigs, horses or ruminants access to feeds containing lincomycin. Ingestion by these species may result in severe gastrointestinal effects. The effects of lincomycin on swine reproductive performance, pregnancy, and lactation have not been determined. Feeds containing lincomycin are not to be fed to swine that weigh more than 250 lb.

FDA page: Open in Animal Drugs @ FDA

Species: Non-Lactating • Beef • Dairy
Composition / specifications
The drug is a suspension containing 10 percent (100 milligrams per milliliter) fenbendazole.
Cattle (beef and dairy)
Indication

For the treatment and control of: Lungworms: Adult Dictyocaulus viviparus; Stomach worms: Adult brown stomach worms (Ostertagia ostertagi), Adult and fourth stage larvae barberpole worms (Haemonchus contortus & H. placei), and Adult and fourth stage larvae small stomach worms (Trichostrongylus axei); Intestinal worms (Adult and fourth stage larvae): hookworms (Bunostomum phlebotomum), thread-necked intestinal worms (Nematodirus helvetianus), small intestinal worms (Cooperia punctata & C. oncophora), bankrupt worms (Trichostrongylus colubriformis), and nodular worms (Oesophagostomum radiatum).

Dosage

Administer orally at a dose of 2.3 mg/lb (5 mg/kg) body weight.

Limitations
Goats
Indication

For the treatment and control of: Stomach worms (adults): Haemonchus contortus and Teladorsagia circumcincta.

Dosage

Administer orally at a dose of 2.3 mg/lb (5 mg/kg) body weight.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Horse, Not For Meat Production
Composition / specifications
The drug is a suspension containing 10 percent (100 milligrams per milliliter) fenbendazole.
Horses
Indication

For the treatment and control of large strongyles (Strongylus edentatus, S. equinus, S. vulgaris, Triodontophorus spp.),small strongyles (Cyathostomum spp., Cylicocyclus spp.,Cylicostephanus spp., Cylicodontophorus spp.), and pinworms (Oxyuris equi).

Dosage

Administer orally at a dose of 2.3 mg/lb (5 mg/kg).

Limitations
Indication

For the treatment and control of ascarids (Parascaris equorum).

Dosage

Administer orally at a dose of 4.6 mg/lb (10 mg/kg).

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Horse, Not For Meat Production • Horse, Foals, Not For Food • Pony, Not For Food
Composition / specifications
The product is an aqueous paste containing 10 percent fenbendazole.
Horses
Indication

For the treatment and control of large strongyles (Strongylus edentatus, S. equinus, S. vulgaris), encysted early 3rd stage (hypobiotic), late 3rd stage and 4th stage cyathostome larvae, small strongyles, pinworms (Oxyuris equi), ascarids (Parascaris equorum), and for the control of arteritis caused by 4th stage larvae of Strongylus vulgaris in horses.

Dosage

For large strongyles, small strongyles, and pinworms, the recommended dose is 5 mg/kg (2.3 mb/lb) administered once orally. For ascarids, the recommended dose is 10 mg/kg (4.6 mg/lb) administered once orally. For treatment and control of hypobiotic (encysted early 3rd stage), late 3rd stage, and 4th stage cyathostome larvae, as well as 4th stage Strongylus vulgaris larvae, the recommended dose is 10 mg/kg (4.6 mg/lb) administered orally daily for 5 consecutive days.

Limitations

Do not use in horses intended for human consumption. Consult your veterinarian for assistance in the diagnosis, treatment and control of parasitism.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
The drug is in granular form containing 22 percent (222 milligrams per gram) fenbendazole.
Dogs
Indication
For the treatment and control of ascarids (Toxocara canis, Toxascaris leonina), hookworms (Ancylostoma caninum, Uncinaria stenocephala), whipworms (Trichuris vulpis), and tapeworms (Taenia pisiformis).
Dosage
50 milligrams per kilogram (22.7 milligrams per pound) daily for 3 consecutive days.
Limitations

Mix the appropriate amount of drug with a small amount of the usual food. Dry dog food may require slight moistening to facilitate mixing. Medicated food must be fully consumed. 

FDA page: Open in Animal Drugs @ FDA

Species: Beef
Composition / specifications
Each pound of molasses block contains 750 milligrams of fenbendazole. Each pound of protein block contains 750 milligrams of fenbendazole.
Cattle (beef)
Indication

For the treatment and control of: Lungworms: Adult Dictyocaulus viviparus; Stomach worms: Adult brown stomach worms (Ostertagia ostertagi), Adult and fourth stage larvae barberpole worms (Haemonchus contortus), fourth stage larvae barberpole worms (H. placei), and Adult and fourth stage larvae small stomach worms (Trichostrongylus axei); Intestinal worms (Adult and fourth stage larvae): hookworms (Bunostomum phlebotomum), thread-necked intestinal worms (Nematodirus helvetianus), small intestinal worms (Cooperia punctata & C. oncophora), bankrupt worms (Trichostrongylus colubriformis), and nodular worms (Oesophagostomum radiatum).

Dosage

Feed free-choice at a rate of 0.1 pound of block per 100 lb body weight (BW) per day for 3 days to deliver a total of 2.27 mg fenbendazole/lb BW (5 mg/kg BW). Do not underdose. Ensure each animal receives a complete dose based on a current body weight. Underdosing may result in ineffective treatment, and encourage the development of parasite resistance. Consult a veterinarian for assistance in the diagnosis, treatment, and control of parasitism.

Limitations

Administer free choice of beef cattle on pasture that have become accustomed to non-medicated block feeding during an adaptation period of 12 to 19 days. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.

FDA page: Open in Animal Drugs @ FDA

Species: Swine, Except For Nursing Piglets • Breeders • Broilers • Layers • Replacements
Composition / specifications
200 mg/mL
Swine (Except Nursing Piglets)
Indication

For the treatment and control of: Lungworms: Adult Metastrongylus apri, adult Metastrongylus pudendotectus; Gastrointestinal worms: Adult and larvae (L3, L4 stages, liver, lung, intestinal forms) large roundworms (Ascaris suum), Adult nodular worms (Oesophagostomum dentatum, O. quadrispinulatum), Adult small stomach worms (Hyostrongylus rubidus), Adult and larvae (L2, L3, L4 stages- intestinal mucosal forms) whipworms (Trichuris suis); and Kidney worms: Adult and larvae Stephanurus dentatus.

Dosage
2.2 mg fenbendazole/kg body weight (BW) (1 mg/lb) daily for 3 consecutive days
Limitations
Chickens (broilers, replacements, breeding, and laying hens)
Indication

For the treatment and control of adult Ascaridia galli in broiler chickens and replacement chickens and for the treatment and control of adult A. galli and Heterakis gallinarum in breeding chickens and laying hens.

Dosage
1 mg/kg BW (0.454 mg/lb)/day for 5 consecutive days
Limitations

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied
Composition / specifications
Each 2-ounce packet contains 2.27 grams (4 percent) of fenbendazole plus other inert ingredients. Each 4-ounce packet contains 1.7 grams (1.5 percent) of fenbendazole plus other inert ingredients.
Swine
Indication
For the removal and control of large roundworms (Ascaris suum); lungworms (Metastrongylus apri); nodular worms (Oesophagostomum dentatum, O. quadrispinulatum); small stomach worms (Hyostrongylus rubidus); whipworms (Trichuris suis; kidney worms (Stephanurus dentatus-mature and immature).
Dosage
3 milligrams fenbendazole per kilogram of body weight (1.36 milligrams per pound per day).
Limitations
Thoroughly mix the contents of the packet(s) with swine ration and administer according to label directions. Feed as sole ration for 3 consecutive days. Can be fed to pregnant sows. No prior withdrawal of feed or water is necessary. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.

FDA page: Open in Animal Drugs @ FDA

Species: Horse, Not For Meat Production
Composition / specifications
The drug is in granular form containing 22 percent (222 milligrams per gram) fenbendazole.
Horses
Indication
For the control of infections of large strongyles (Strongylus edentatus, S. equinus, S. vulgaris), small strongyles, pinworms (Oxyuris equi), and ascarids (Parascaris equorum).
Dosage
5 milligrams per kilogram (2.3 milligrams per pound) for the control of large strongyles, small strongyles, and pinworms; 10 milligrams per kilogram for the control of ascarids.
Limitations
Sprinkle the appropriate amount of drug on a small amount of the usual grain ration. Prepare for each horse individually. Withholding feed or water is not necessary. Retreat in 6 to 8 weeks if required. Do not use in horses intended for food. Consult your veterinarian assistance in the diagnosis, treatment, and control of parasitism.

FDA page: Open in Animal Drugs @ FDA

Official Documents (FDA)

Direct links to FDA-hosted PDFs and SPL packages (when available).

Documents
  • Summary

    For the treatment and control of:
    Lungworms: Adult Dictyocaulus viviparus;
    Stomach worms: Adult brown stomach worms (Ostertagia ostertagi), Adult and fourth stage larvae barberpole worms (Haemonchus contortus & H. placei), and Adult and fourth stage larvae small stomach worms (Trichostrongylus axei);
    Intestinal worms (Adult and fourth stage larvae): hookworms (Bunostomum phlebotomum), thread-necked intestinal worms (Nematodirus helvetianus), small intestinal worms (Cooperia punctata & C. oncophora), bankrupt worms (Trichostrongylus colubriformis), and nodular worms (Oesophagostomum radiatum).
    Goats- 2.3 mg/lb (5 mg/kg) body weight for the treatment and control of: Stomach worms (adults): Haemonchus contortus and Teladorsagia circumcincta.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    Fenbendazole is indicated for the removal of:
    Lungworms: adult (Metastrongylus apri, M. pudendotectus)
    Gastrointestinal worms: adult and larvae (L3, L4 stages – liver, lung, and intestinal forms) large roundworms (Ascaris suum), adult nodular worms (Oesophagostomum dentatum, O. quadrispinulatum), small stomach worms (Hyostrongylus rubidus), adult and larvae (L2, L3, L4 stages – intestinal mucosal forms) whipworms (Trichuris suis);
    Kidneyworms: adult and larvae (Stephanurus dentatus) Bacitracin methylene disalicylate is indicated for:
    Increased rate of weight gain and improved feed efficiency in growing and finishing swine;
    Control of clostridial enteritis in suckling pigs caused by Clostridium perfringens when fed to pregnant sows during the period from 14 days before farrowing through 21 days after farrowing;
    Control of swine dysentery associated with Treponema hyodysenteriae in growing and finishing swine on premises with a history of swine dysentery but where signs of disease have not yet occurred or following an approved treatment of the disease

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    This supplement provides for addition of wild quail with the indication for the treatment and control of Aulonocephalus spp. in wild quail.

  • Summary

    This supplement provides for 1) tolerances and tissue withdrawal periods in cattle, swine, and turkeys, and a milk discard time in cattle in accordance with a repartitioning of the acceptable daily intake (ADI); and 2) the addition of fourth stage larval indications for barberpole worms (Haemonchus contortus & H. placei), small stomach worms (Trichostrongylus axei), hookworms (Bunostomum phlebotomum), thread-necked intestinal worms (Nematodirus helvetianus), small intestinal worms (Cooperia punctata & C. oncophora), bankrupt worms (Trichostrongylus colubriformis), and nodular worms (Oesophagostomum radiatum) in cattle.

  • Summary
    This supplement provides for the Type A medicated article to be used to manufacture a free-choice liquid Type C medicated feed for use in dairy and beef cattle.
  • Summary
    This supplement to NADA 131-675 provides for a new claim for control of gastrointestinal worms in horses [large strongyles (Strongylus edentatus, S. equinus, S. vulgaris, Triodontophorus spp.), small strongyles (Cyathostomum spp., Cylicocyclus spp., Cylicostephanus spp.), pinworms (Oxyuris equi), and ascarids (Parascaris equorum)].
  • Summary
    This supplement provides for the addition of growing turkeys to the previously approved SAFE-GUARD® Type A medicated article labeling.
  • Summary
    This supplement provides for the revision 21 CFR 556.275 by establishing tolerances for residues in swine liver and muscle and adding allowable daily intake (ADI).
  • Summary

    This supplement provides for an additional Type A medicated article (premix) containing 8% fenbendazole for the same indications for use in Type C medicated swine feed as the currently approved Type A medicated articles containing 4% and 20% fenbendazole. See 21 CFR 558.258.

  • Summary
    This supplemental approval provides for the minor use
  • EA 131-675
  • FONSI 131-675
  • EA 131-675
  • FONSI 131-675
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    This supplement provides for 1) tolerances, a tissue withdrawal period, and a milk discard time in accordance with a repartitioning of the ADI; and 2) the addition of fourth stage larval indications for barberpole worms (Haemonchus contortus and H. placei), small stomach worms (Trichostrongylus axei), hookworms (Bunostomum phlebotomum), thread-necked intestinal worms (Nematodirus helvetianus), small intestinal worms (Cooperia punctata & C. oncophora), bankrupt worms (Trichostrongylus colubriformis), and nodular worms (Oesophagostomum radiatum).

  • Summary
    This supplement provides for the use of fenbendazole for the removal and control of gastrointestinal parasites and lungworm in dairy cattle of breeding age.
  • EA 132-872
  • FONSI 132-872
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    Fenbendazole is indicated for the removal of: LUNGWORMS; GASTROINTESTINAL WORMS; KIDNEYWORMS ..1. increased rate of weight gain in growing-finishing swine 2. for control of swine dysentery; for use in swine on premises with a history of swine dysentery, but where symptoms have not yet occurred 3. for treatment swine dysentery 4. for reduction in the severity of swine mycoplasmal pneumonia caused by Mycoplasma hyopneumoniae.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    This supplement provides for tolerances, a tissue withdrawal period, and a milk discard time in cattle; and a tolerance and tissue withdrawal period in goats in accordance with a repartitioning of the acceptable daily intake (ADI).

  • Summary

    1) The marketing status of fenbendazole suspension for use in goats is changed from prescription (Rx) to over-the-counter (OTC) by removing goats from the Panacur® Suspension 10% label and by adding goats to the Safe-GuardR Suspension 10% label. The formulation of the two products is identical. 2) The indications for use in goats are revised from "for the removal and control of stomach and intestinal worms Haemonchus contortus and Ostertagia circumcincta" to "for the removal and control of stomach worms (adults) Haemonchus contortus and Teladorsagia circumcincta.¨

  • Summary
    This supplement provides for establishing tolerances for residues of parent fenbendazole in muscle of cattle and goats.
  • Summary

    ...effectively removes and controls infections in cattle due to Dictyocaulus viviparus, stomach worms, and intestinal worms

  • Summary

    This supplement provides for an expanded use of fenbendazole in a new species (goats).

  • EA 128-620
  • FONSI 128-620
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For treatment of encysted mucosal cyathostome (small strongyle) larvae including hypobiotic early third stage, late third stage and fourth stage larvae at 10 mg/kg/day for 5 consecutive days.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplement provides for a change from prescription (Rx) to OTC status for fenbendazole granules 22.2% packets to be marketed under the trade name PANACUR®-C.  The jar presentation (Panacur®) will remain prescription (Rx) as it is also labeled for use in other species of carnivorous/omnivorous animals.  The jar presentation will continue to be marketed under the Panacur® trade name.
  • Summary

    This supplement provides a claim as an anthelmintic in the following species within the families Felidae and Ursidae: lion (Panthera leo), tiger (Panthera tigris) cheetah (Acinonyx jubatus) Puma (Felis concolor), Jaguars (Panthera onca), Leopard (Panthera pardus), Panther (Panthera spp), Grizzly Bear (Ursus horribilis), Polar Bear (Ursus maritimus), and Black Bear (Ursus americanus).

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    This supplement provides for 1) a tolerance and tissue withdrawal periods in accordance with a repartitioning of the ADI; and 2) the addition of fourth stage larval indications for barberpole worms (Haemonchus contortus and H. placei), small stomach worms (Trichostrongylus axei), hookworms (Bunostomum phlebotomum), thread-necked intestinal worms (Nematodirus helvetianus), small intestinal worms (Cooperia punctata & C. oncophora), bankrupt worms (Trichostrongylus colubriformis), and nodular worms (Oesophagostomum radiatum).

  • Summary
    The original approval provided for a 25 lb. medicated molasses block containing 750 milligrams of fenbendazole per pound as a beef cattle anthelmintic. The molasses block requires an 11-day withdrawal. This supplemental approval provides for a 33-1/2 pound cold press medicated 20% protein feedblock containing 750 milligrams of fenbendazole per pound as a beef cattle anthelmintic. The cold press 20% protein block requires a 16-day withdrawal period.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    This supplement provides for the following: 1) the addition of "and laying hens" to the indication for treatment and control of adult A. galli and H. gallinarum; 2) the removal of the limitation of "intended to become breeding chickens" from "replacement chickens" in the treatment and control portion of the A. galli only part of the indication; and 3) the removal of the limitation, "Not for use in laying hens and replacement chickens intended to become laying hens" in the indication.

  • Summary
    This supplement provides for the addition of swine, except for nursing piglets, for the following indications: For the treatment and control of Lungworms: Adult Metastrongylus apri, adult Metastrongylus pudendotectus; Gastrointestinal worms: Adult and larvae (L3, L4 stages, liver, lung, intestinal forms) large roundworms ( Ascaris suum); nodular worms ( Oesophagostomum dentatum, O. quadrispinulatum); small stomach worms ( Hyostrongylus rubidus); Adult and larvae (L2, L3, L4 stages – intestinal mucosal forms) whipworms ( Trichuris suis); and Kidney worms: Adult and larvae Stephanurus dentatus.
  • Summary
    For the treatment and control of adult Ascaridia galli in broiler chickens and replacement chickens intended to become breeding chickens and for the treatment and control of adult A. galli and Heterakis gallinarum in breeding chickens.
  • EA 141-449
  • FONSI 141-449
  • EA 141-449
  • FONSI 141-449
  • EA 141-449
  • FONSI 141-449
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Usage

For the treatment and control of large strongyles ( Strongylus edentatus , S. equinus , S. vulgaris , Triodontophorus spp.),small strongyles ( Cyathostomum spp., Cylicocyclus spp., Cylicostephanus spp., Cylicodontophorus spp.), and pinworms ( Oxyuris equi ). For the treatment and control of ascarids ( Parascaris equorum ). For the control of infections of large strongyles (Strongylus edentatus, S. equinus, S. vulgaris), small strongyles, pinworms (Oxyuris equi), and ascarids (Parascaris equorum).

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Sprinkle the appropriate amount of drug on a small amount of the usual grain ration. Prepare for each horse individually. Withholding feed or water is not necessary. Retreat in 6 to 8 weeks if required. Do not use in horses intended for food. Consult your veterinarian assistance in the diagnosis, treatment, and control of parasitism. Do not use in horses intended for human consumption. Consult your veterinarian for assistance in the diagnosis, treatment and control of parasitism. Mix the appropriate amount of drug with a small amount of the usual food. Dry dog food may require slight moistening to facilitate mixing. Medicated food must be fully consumed.

Side Effects

No approved side-effect narrative is linked yet.

openFDA reaction signals are available for Dog 56 and Cat 20 (view top reported reactions).

Top Reported Reactions (openFDA)

Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).

Dog
Digestive
Vomiting (148) Diarrhea (126) Diarrhea (2) Diarrhea (2) Diarrhea (2) Diarrhea (2) Diarrhea (2) Diarrhea (2)
Neurologic
Tiredness (lethargy) (72) Tiredness (lethargy) (3) Tiredness (lethargy) (3) Tiredness (lethargy) (3) Tiredness (lethargy) (3) Tiredness (lethargy) (3) Tiredness (lethargy) (3)
Effectiveness
Lack of efficacy (endoparasite) - hookworm (235) Lack of efficacy (endoparasite) - tapeworm (74) Lack of efficacy (endoparasite) - NOS (67) Lack of efficacy (endoparasite) - hookworm (18) Lack of efficacy (endoparasite) - hookworm (18) Lack of efficacy (endoparasite) - hookworm (18) Lack of efficacy (endoparasite) - hookworm (18) Lack of efficacy (endoparasite) - hookworm (18) Lack of efficacy (endoparasite) - hookworm (18) Lack of efficacy - NOS (3) Lack of efficacy - NOS (3) Lack of efficacy - NOS (3) Lack of efficacy - NOS (3) Lack of efficacy - NOS (3) Lack of efficacy - NOS (3) Lack of efficacy (endoparasite) - roundworm NOS (2) Lack of efficacy (endoparasite) - roundworm NOS (2) Lack of efficacy (endoparasite) - roundworm NOS (2) Lack of efficacy (endoparasite) - roundworm NOS (2) Lack of efficacy (endoparasite) - roundworm NOS (2) Lack of efficacy (endoparasite) - roundworm NOS (2)
Other
INEFFECTIVE, HOOKS (131) Other abnormal test result NOS (89) Death (3) Death (3) Death (3) Death (3) Death (3) Death (3) Elevated alanine aminotransferase (2) Elevated alanine aminotransferase (2) Elevated alanine aminotransferase (2) Elevated alanine aminotransferase (2) Elevated alanine aminotransferase (2) Elevated alanine aminotransferase (2) Fever (2) Fever (2) Fever (2) Fever (2) Fever (2) Fever (2)
Cat
Digestive
Vomiting (13) Diarrhea (9) Decreased appetite (8) Vomiting (1) Vomiting (1) Vomiting (1) Vomiting (1) Vomiting (1) Vomiting (1)
Neurologic
Tiredness (lethargy) (9)
Effectiveness
Lack of efficacy (endoparasite) - roundworm NOS (5)
Other
Death (7) Decreased activity (5) Not eating (5) Death (1) Death (1) Death (1) Death (1) Death (1) Death (1)

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Crossbred Canine/dog, Unknown, 6 month, 15.88 kilogram • Drug: MSK, Unknown, Dose: 50 Milligram per kilogram, Frequency: 1 per day • Reactions: Lack of efficacy - NOS, Lack of efficacy (endoparasite) - hookworm • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-055986
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Unknown
  • Age: 6.00 Month
  • Weight: 15.880 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Dose: 50 Milligram per kilogram
  • Frequency: 1 per day
Reactions Reported:
Lack of efficacy - NOS Lack of efficacy (endoparasite) - hookworm
Outcomes: Outcome Unknown

Dog, Retriever - Labrador, Female, 1 year, 21.818 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Lack of efficacy (endoparasite) - hookworm • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055119
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 1.00 Year
  • Weight: 21.818 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Unassigned
Reactions Reported:
Lack of efficacy (endoparasite) - hookworm
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 7 week, 0.363 kilogram • Drug: MSK, Oral, Dose: 1 Other per animal • Reactions: Death • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-052904
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 7.00 Week
  • Weight: 0.363 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Dose: 1 Other per animal
Reactions Reported:
Death
Outcomes: Died

Dog, Dog (unknown), Female, 15.87 kilogram • Drug: MSK, Unknown • Reactions: Lack of efficacy (endoparasite) - hookworm • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-054252
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Weight: 15.870 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Lack of efficacy (endoparasite) - hookworm
Outcomes: Outcome Unknown

Dog, Dog (unknown), Female, 30.85 kilogram • Drug: MSK, Unknown • Reactions: Lack of efficacy (endoparasite) - heartworm • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-054376
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Weight: 30.850 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Lack of efficacy (endoparasite) - heartworm
Outcomes: Outcome Unknown

Dog, Dog (unknown), Female, 20.412 kilogram • Drug: MSK, Unknown • Reactions: Lack of efficacy (endoparasite) - hookworm • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-052827
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Weight: 20.412 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Lack of efficacy (endoparasite) - hookworm
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Male, 3.58 year, 4.3 kilogram • Drug: MSK, Unknown • Reactions: Vomiting • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-052893
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 3.58 Year
  • Weight: 4.300 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Vomiting
Outcomes: Recovered/Normal

Cat, Domestic Shorthair, Female, 2 year, 3.039 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Lack of efficacy - NOS, Elevated amylase, Anaemia NOS, Neutropenia, Monocytosis… • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2025-US-045743
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 2.00 Year
  • Weight: 3.039 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Unassigned
Reactions Reported:
Lack of efficacy - NOS Elevated amylase Anaemia NOS Neutropenia Monocytosis Elevated globulins Decreased blood urea nitrogen (BUN) or creatinine Trouble breathing (dyspnea) Death by euthanasia
Outcomes: Euthanized

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

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