Skip to main content

Need urgent help? Start triage first, then route to emergency care.

Meds A-Z

Tramadol

Detailed information about Tramadol

Official label facts Owner quick guide first Marketing clearly labeled
Showing simplified owner view. Switch to Vet View for full technical detail.

Pet Owner Quick Guide

Start here: what this medicine is for, what it does, and when it's usually needed.

Usually used for:

Use this medication only when your veterinarian confirms it matches your pet's condition.

What it does:

Use this medication only when your veterinarian confirms it matches your pet's condition.

When it's needed:

Use this medication only when your veterinarian confirms it matches your pet's condition.

Commonly reported reactions:

  • (2 reports)
  • (1 reports)
  • (1 reports)

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Talk to a Vet / Find a Vet Near You
Image coming soon
Tramadol

Tramadol

Drug type: Generic ingredient • Generic profile No FDA branded products linked

Species: Both

Manufacturer: MSK

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: MSK
Form: No source yet
Identifiers:

No source yet.

Source metadata: No source yet.

Warnings / Contraindications

No contraindication summary is linked yet.

No owner-focused warning rows are linked yet.

Source metadata: No source yet.

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
24
Species represented
2
Most Reported Reactions
Reaction Cases Species Serious cases
2 Cat, Dog 0
1 Cat 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1

Species coverage: Dog (24) Cat (8)

View detailed reaction table
Reaction Species Seriousness Frequency Reports
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Non-serious - 1
Cat Non-serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Cat Non-serious - 1
Dog Serious - 1
Cat Non-serious - 1
Dog Non-serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Non-serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Non-serious - 1
Cat Serious - 1
Cat Non-serious - 1
Source metadata:

Storage & Handling

No storage/handling guidance is linked yet.

Source metadata: No source yet.

Documents

Official label facts are separated from secondary summaries.

No linked label PDFs or safety notices yet.

Official label facts

No source yet.

Secondary summaries

No source yet.

Source metadata: No source yet.

Promotional Materials (Marketing)

This content is marketing material and not clinical guidance.

No marketing assets are linked yet.

No source yet.

Source metadata: No source yet.
Talk to a Vet / Find a Vet Near You
Technical appendix (vet reference)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 16, 2026, 11:02 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:20 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 56 Cat 8 View
Case summaries: 10 (showing 8) View
openFDA reports are unverified and do not prove causation.

Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Abnormal echocardiogram (1) Abnormal radiograph finding (1) Abnormal ultrasound finding (1) Behavioural disorder NOS (1) Behavioural disorder NOS (1) Bone and joint disorder NOS (1) Cardiac disorder NOS (1) Colitis (1) Death by euthanasia (1) Decreased appetite (1) Diarrhoea (1) Dilated pupils (1) Disorientation (1) Elevated alanine aminotransferase (ALT) (1) Elevated amylase (1) Elevated gamma-glutamyl transferase (GGT) (1)

Data Sources & Revision History

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Lack of ef… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

No linked FDA product applications are available for this ingredient yet.

Usage

No approved usage text is linked yet for this ingredient.

  • Catalog species: Both
  • Safety reports available: 10 openFDA case summaries (view)

Contraindications

No approved contraindication text is linked yet. Review FDA label highlights and openFDA safety reports before making treatment decisions.

Side Effects

No approved side-effect narrative is linked yet.

openFDA reaction signals are available for Dog 56 and Cat 8 (view top reported reactions).

Top Reported Reactions (openFDA)

Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).

Dog
Digestive
Vomiting (495) Diarrhea (269) Loss of appetite (187)
Skin & allergy
Joint swelling (1)
Neurologic
Tiredness (lethargy) (342)
Behavior
Behavioral disorder (unspecified) (1) Behavioral disorder (unspecified) (1) Behavioral disorder (unspecified) (1) Behavioral disorder (unspecified) (1) Behavioral disorder (unspecified) (1) Behavioral disorder (unspecified) (1)
Effectiveness
Lack of efficacy - NOS (194)
Other
Death by euthanasia (224) Elevated alanine aminotransferase (191) Other abnormal test result NOS (164) Abnormal radiograph finding (2) Abnormal radiograph finding (2) Bone and joint disorder NOS (2) Bone and joint disorder NOS (2) Unable to walk (2) Unable to walk (2) Unable to walk (2) Unable to walk (2) Unable to walk (2) Unable to walk (2) Abnormal echocardiogram (1) Abnormal echocardiogram (1) Abnormal echocardiogram (1) Abnormal echocardiogram (1) Abnormal echocardiogram (1) Abnormal radiograph finding (1) Abnormal radiograph finding (1) Abnormal radiograph finding (1) Abnormal ultrasound finding (1) Abnormal ultrasound finding (1) Abnormal ultrasound finding (1) Abnormal ultrasound finding (1) Abnormal ultrasound finding (1) Arthritis (1) Arthritis (1) Bone and joint disorder NOS (1) Bone and joint disorder NOS (1) Bone and joint disorder NOS (1) Bone and joint disorder NOS (1) Cardiac disorder NOS (1) Cardiac disorder NOS (1) Cardiac disorder NOS (1) Cardiac disorder NOS (1) Cardiac disorder NOS (1) Colitis (1) Colitis (1) Colitis (1) Disorientation (1) INEFFECTIVE, ANESTHESIA (1) Inappropriate urination (1) Panting (1)
Cat
Behavior
Behavioral disorder (unspecified) (2)
Effectiveness
Lack of efficacy - NOS (3)
Other
Dilated pupils (3) Death (2) Fever (2) Other abnormal test result NOS (2) Abnormal cytology (1) Abnormal red blood cell (1)

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, ['Retriever - Labrador', 'Dog (unknown)'], Male, 14 year, 15.876 kilogram • Drug: MSK, Oral • Reactions: Seizure NOS, Inappropriate urination, Walking difficulty, Urinary incontinence, Swelling NOS… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-056004
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 14.00 Year
  • Weight: 15.876 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
Reactions Reported:
Seizure NOS Inappropriate urination Walking difficulty Urinary incontinence Swelling NOS Unable to walk
Outcomes: Ongoing

Dog, ['Bulldog - American', 'Dog (unknown)'], Female, 9 year, 27.669 kilogram • Drug: MSK, Solution/drops, Unknown • Reactions: Unable to walk, Joint swelling, Weight loss, Bone and joint disorder NOS, Splenic neoplasm NOS • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-054930
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 9.00 Year
  • Weight: 27.669 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Solution/drops
Reactions Reported:
Unable to walk Joint swelling Weight loss Bone and joint disorder NOS Splenic neoplasm NOS
Outcomes: Ongoing

Dog, Mixed (Dog), Mixed, 5 year, 3.8 kilogram • Drug: MSK, Intravenous, Dose: 4 Milligram per kilogram • Reactions: INEFFECTIVE, ANESTHESIA • Outcome: Recovered/Normal

  • Report ID: KOR-USFDACVM-2025-KR-000003
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Mixed
  • Age: 5.00 Year
  • Weight: 3.800 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intravenous
  • Dose: 4 Milligram per kilogram
Reactions Reported:
INEFFECTIVE, ANESTHESIA
Outcomes: Recovered/Normal

Dog, Terrier - West Highland White, Female, 16 year, 8.618 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Panting, Behavioral disorder (unspecified), Disorientation • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-050473
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 16.00 Year
  • Weight: 8.618 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Panting Behavioral disorder (unspecified) Disorientation
Outcomes: Ongoing

Dog, Siberian Husky, Female, 20 month, 29.211 kilogram • Drug: MSK, Unknown • Reactions: Vomiting, Diarrhea, Vocalisation, Hyperactivity, Low platelet count… • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-049797
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 20.00 Month
  • Weight: 29.211 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Vomiting Diarrhea Vocalisation Hyperactivity Low platelet count Hyperglycaemia Elevated gamma-glutamyl transferase Elevated amylase Hypochloraemia Elevated alanine aminotransferase Increased coagulation time Abnormal radiograph finding Cardiac disorder NOS Pulmonary disorder NOS Hepatomegaly Intestinal disorder NOS Fluid in abdomen NOS Abnormal echocardiogram Gastroenteritis Colitis Gall bladder & bile duct disorder NOS Abnormal ultrasound finding
Outcomes: Recovered/Normal

Cat, Domestic Shorthair, Female, 17 year, 5.897 kilogram • Drug: MSK, Tablet, Oral • Reactions: Lameness, Death by euthanasia • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2024-US-049312
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 17.00 Year
  • Weight: 5.897 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
Reactions Reported:
Lameness Death by euthanasia
Outcomes: Euthanized

Cat, Domestic Shorthair, Female, 18 year, 3.683 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Pyoderma • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2024-US-008646
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 18.00 Year
  • Weight: 3.683 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Unassigned
Reactions Reported:
Pyoderma
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 2 year, 4.1 kilogram • Drug: MSK, Unknown • Reactions: Not eating, Growling, Lack of efficacy - NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2023-US-002091
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 2.00 Year
  • Weight: 4.100 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Not eating Growling Lack of efficacy - NOS
Outcomes: Outcome Unknown

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

Share Your Thoughts

Let others know your experience or advice regarding this medication.

This medication has not been reviewed by a veterinarian yet.