Meds A-Z
Sometribove
Detailed information about Sometribove
Pet Owner Quick Guide
Start here: what this medicine is for, what it does, and when it's usually needed.
Usually used for:
To increase production of marketable milk in healthy lactating dairy cows.
What it does:
To increase production of marketable milk in healthy lactating dairy cows.
When it's needed:
Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections within 2 weeks of expected slaughter to minimize injection site b...
Call your vet sooner if you notice:
- Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections within 2 weeks of expected slaughter to minimize injection site blemishes on carcass.There is no milk discard or preslaughter withdrawal period.Use may reduce pregnancy rates and increase days open. Treated cows are at an increased risk for mastitis and higher milk somatic cell counts. Use care to differentiate increased body temperature due to use of this product from an increased body temperature that may occur due to illness. Cows treated with this product may have more enlarged hocks and disorders of the foot region. Use may reduce hemoglobin and hematocrit values during treatment.Human warning: Avoid prolonged or repeated contact with eyes and skin.
What to ask your vet today:
- Is this medicine the right fit for my pet’s current symptoms?
- Which warning signs mean I should call back right away?
- How should I handle missed doses or refusal to take the medicine?
Sometribove
Drug type: Generic ingredient • Branded profile • FDA branded products available
Species: Both
Manufacturer: Union Agener, Inc.
Quick Facts
Official label facts first, then secondary summaries. Marketing content is separated below.
- https://animaldrugsatfda.fda.gov/adafda/views/#/home/previewsearch/140872 · official_label · FDA application profile
- https://animaldrugsatfda.fda.gov · fda_animal_drugs · Medication usage source
Warnings / Contraindications
Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections within 2 weeks of expected slaughter to minimize injection site blemishes on carcass.There is no milk discard or preslaughter withdrawal period.Use may reduce pregnancy rates and increase days open. Treated cows are at an increased risk for mastitis and higher milk somatic cell counts. Use care to differentiate increased body temperature due to use of this product from an increased body temperature that may occur due to illness. Cows treated with this product may have more enlarged hocks and disorders of the foot region. Use may reduce hemoglobin and hematocrit values during treatment.Human warning: Avoid prolonged or repeated contact with eyes and skin.
- High: Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections within 2 weeks of expected slaughter to minimize injection site blemishes on carcass.There is no milk discard or preslaughter withdrawal period.Use may reduce pregnancy rates and increase days open. Treated cows are at an increased risk for mastitis and higher milk somatic cell counts. Use care to differentiate increased body temperature due to use of this product from an increased body temperature that may occur due to illness. Cows treated with this product may have more enlarged hocks and disorders of the foot region. Use may reduce hemoglobin and hematocrit values during treatment.Human warning: Avoid prolonged or repeated contact with eyes and skin.
- https://animaldrugsatfda.fda.gov · fda_animal_drugs · Contraindication source
Adverse Reactions
Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.
No adverse-reaction rows are linked yet.
- https://open.fda.gov/apis/animalandveterinary/ · openfda · openFDA adverse-event data
Storage & Handling
No storage/handling guidance is linked yet.
Documents
Official label facts are separated from secondary summaries.
Official documents: 6 • Secondary summaries: 0
- ucm050024.pdf · FOI
- ucm050023.pdf · FOI
- ucm050022.pdf · FOI
- 140-872 · EA
- 140-872 · FONSI
- Posilac™ · SPL
No source yet.
- https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/514 · document · FOI
- https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/513 · document · FOI
- https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/512 · document · FOI
- https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadEA/76 · document · EA
- https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFonsi/76 · document · FONSI
- https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1427/Posilac%E2%84%A2 · document · SPL
Promotional Materials (Marketing)
This content is marketing material and not clinical guidance.
No marketing assets are linked yet.
No source yet.
Technical appendix (vet reference)
Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.
At a Glance
Quick facts and links to official labeling and safety signals.
- Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 10:44 PM UTC
-
Animal Drugs @ FDA:
Source FDA
| Refreshed Feb 16, 2026, 11:00 AM UTC
Applications/products are imported from FDA export data.
-
Animal Drugs @ FDA previews:
Source FDA
| Refreshed Feb 9, 2026, 3:05 AM UTC
Label highlights/doc links are fetched from FDA preview endpoints.
-
Animal Drug Product Listing Directory (NDC):
Source FDA
| Refreshed Feb 16, 2026, 11:00 AM UTC
Package/product NDCs from FDA’s electronic listing directory (XLS).
Diagnosis-code mappings are not available for this medication yet.
Counseling and Monitoring Highlights
Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.
- Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections within 2 weeks of expected slaughter to minimize injection site blemishes on carcass.There is no milk discard or preslaughter withdrawal period.Use may reduce pregnancy rates and increase days open. Treated cows are at an increased risk for mastitis and higher milk somatic cell counts. Use care to differentiate increased body temperature due to use of this product from an increased body temperature that may occur due to illness. Cows treated with this product may have more enlarged hocks and disorders of the foot region. Use may reduce hemoglobin and hematocrit values during treatment.Human warning: Avoid prolonged or repeated contact with eyes and skin. (Contraindication, High)
Identifiers & Packages
Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.
| Package NDC | Product NDC | Form / Route | Status |
|---|---|---|---|
| 86106-0225-1 | 86106 | - | |
| 86106-0225-2 | 86106 | - | |
| 86106-0225-3 | 86106 | - |
Enriched Documents
Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.
-
ucm050022.pdf
• FOI summary • Official
• May 6, 2020
FDA FOI summary for application 140872
-
ucm050023.pdf
• FOI summary • Official
• May 6, 2020
FDA FOI summary for application 140872
-
ucm050024.pdf
• FOI summary • Official
• May 6, 2020
FDA FOI summary for application 140872
Data Sources & Revision History
Every non-trivial field is expected to include provenance and update timestamps.
- contraindications: Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections with… (Official, 2026-02-12)
- usage: To increase production of marketable milk in healthy lactating dairy cows. (Official, 2026-02-12)
- contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
- usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
FDA Products & Applications (Animal Drugs @ FDA)
Official sponsor/proprietary-name/application-status records linked by active ingredient.
| Product | Sponsor | Application | Status | Published |
|---|---|---|---|---|
|
Posilac™
OTC
Bovine Somatotropin (Sometribove Zinc)
Liquid (Suspension)
• Subcutaneous
|
Union Agener, Inc. | NADA 140-872 | Approved | May 6, 2020 |
Data source: FDA Animal Drugs @ FDA (public search export).
What It's For (FDA Label Highlights)
Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.
Composition / specifications
To increase production of marketable milk in healthy lactating dairy cows.
Inject 500 milligrams every 14 days beginning during the 9th or 10th week (57 to 70 days) after calving and continue until the end of lactation.
Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections within 2 weeks of expected slaughter to minimize injection site blemishes on carcass.There is no milk discard or preslaughter withdrawal period.Use may reduce pregnancy rates and increase days open. Treated cows are at an increased risk for mastitis and higher milk somatic cell counts. Use care to differentiate increased body temperature due to use of this product from an increased body temperature that may occur due to illness. Cows treated with this product may have more enlarged hocks and disorders of the foot region. Use may reduce hemoglobin and hematocrit values during treatment.Human warning: Avoid prolonged or repeated contact with eyes and skin.
FDA page: Open in Animal Drugs @ FDA
Official Documents (FDA)
Direct links to FDA-hosted PDFs and SPL packages (when available).
-
FOI ucm050024.pdf
Summary
This Freedom of Information Summary describes the basis for labeling changes to modify/remove precautions pertaining to target animal safety and reproduction. -
FOI ucm050023.pdf
Summary
A study was conducted to evaluate the effectiveness and animal safety of sometribove given by subcutaneous injection in the neck area. -
FOI ucm050022.pdf
Summary
For increased production of marketable milk in lactating dairy cows. -
EA 140-872
-
FONSI 140-872
- Posilac™ (ZIP)
FDA page: Open in Animal Drugs @ FDA
Usage
To increase production of marketable milk in healthy lactating dairy cows.
Source: FDA Animal Drugs @ FDA • Reference
Contraindications
Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections within 2 weeks of expected slaughter to minimize injection site blemishes on carcass.There is no milk discard or preslaughter withdrawal period.Use may reduce pregnancy rates and increase days open. Treated cows are at an increased risk for mastitis and higher milk somatic cell counts. Use care to differentiate increased body temperature due to use of this product from an increased body temperature that may occur due to illness. Cows treated with this product may have more enlarged hocks and disorders of the foot region. Use may reduce hemoglobin and hematocrit values during treatment.Human warning: Avoid prolonged or repeated contact with eyes and skin.
Side Effects
No approved side-effect narrative is linked yet.
Adverse Event Case Summaries (openFDA)
These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.
No case-level openFDA reports are linked for this medication yet.
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Overdose Information
No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.
Storage & Handling
No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.
Share Your Thoughts
Let others know your experience or advice regarding this medication.
This medication has not been reviewed by a veterinarian yet.