Skip to main content

Need urgent help? Start triage first, then route to emergency care.

Meds A-Z

Clavulanate Potassium

Detailed information about Clavulanate Potassium

Official label facts Owner quick guide first Marketing clearly labeled
Showing simplified owner view. Switch to Vet View for full technical detail.

Pet Owner Quick Guide

Start here: what this medicine is for, what it does, and when it's usually needed.

Usually used for:

For the treatment of skin and soft tissue infections such as wounds, abscesses, cellulitis, superficial/juvenile and deep pyoderma due to susceptible strains of the following organisms: ß-lactamase-producing Staphylococc...

What it does:

Clavamox Drops are indicated in the treatment of skin and soft tissue infections such as wounds, abscesses, cellulitis, superficial/juvenile and deep pyoderma due to susceptible strains of the following organisms: ß-lact...

When it's needed:

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Call your vet sooner if you notice:

  • Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Commonly reported reactions:

  • (1 reports)
  • (1 reports)
  • (1 reports)

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Talk to a Vet / Find a Vet Near You
Image coming soon
Clavulanate Potassium

Clavulanate Potassium

Drug type: Generic ingredient • Branded profile FDA branded products available

Species: Both

Manufacturer: Dechra Veterinary Products LLC

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Dechra Veterinary Products LLC
Form: Liquid, Suspension, Tablet
Identifiers:
ANADA: 200592 ANADA: 200604 ANADA: 200702 ANADA: 200709 NADA: 55101 NDC Package: 11695-6991-1 NDC Package: 11695-6992-1 NDC Package: 11695-6993-1 NDC Package: 11695-6994-1 NDC Package: 11695-7007-1 NDC Package: 13744-540-01 NDC Package: 13744-541-01 NDC Package: 13744-542-01 NDC Package: 13744-543-01 NDC Package: 17033-440-07 NDC Package: 17033-440-21 NDC Package: 17033-441-07 NDC Package: 17033-441-21 NDC Package: 17033-442-07 NDC Package: 17033-442-21
Source metadata:

Warnings / Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

  • High: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
29
Species represented
2
Most Reported Reactions
Reaction Cases Species Serious cases
1 Cat 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Dog 1
1 Cat 1

Species coverage: Dog (24) Cat (8)

View detailed reaction table
Reaction Species Seriousness Frequency Reports
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Non-serious - 1
Cat Non-serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Dog Serious - 1
Cat Non-serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Dog Serious - 1
Cat Serious - 1
Source metadata:

Storage & Handling

No storage/handling guidance is linked yet.

Source metadata: No source yet.

Documents

Official label facts are separated from secondary summaries.

Official documents: 10 • Secondary summaries: 0

Secondary summaries

No source yet.

Promotional Materials (Marketing)

This content is marketing material and not clinical guidance.

No marketing assets are linked yet.

No source yet.

Source metadata: No source yet.
Talk to a Vet / Find a Vet Near You
Technical appendix (vet reference)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source PetWisePlus | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Feb 16, 2026, 11:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 16, 2026, 11:03 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:20 AM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: Amoxicillin and Clavulanate Potassium Tablets Amoxicillin and Clavulanate Potassium for Oral Suspension Clavacillin® Clavamox® Drops
Case-reported brands (openFDA): MSK
Catalog species: Both FDA-labeled species: Cat, Dog
Rx/OTC: RX
Form/route: Liquid, Suspension, Tablet Oral
Applications: ANADA 200-709 • ANADA 200-702 • NADA 55101 • ANADA 200-604 • ANADA 200-592
Documents: 5 (FOI: 5) • SPL: 5 Label highlights Official documents
Safety (openFDA)
Top reactions: Dog 8 Cat 38 View
Case summaries: 4 (showing 4) View
openFDA reports are unverified and do not prove causation.

Explore
Linked using: Fda_Label (0.95), Fda_Label (0.95), Fda_Label (0.95)

Diagnosis Codes
ICD10_CM: K05.6
Periodontal disease, unspecified

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Federal law restricts this drug to use by or on the order of a licensed veterinarian. (Contraindication, High)
Top reaction signals
Ataxia (1) Brain disorder NOS (1) Bruising (1) Circling - neurological disorder (see also Behavioural disorders) (1) Color, Abnormal (1) Diarrhoea (1) Distension of abdomen (1) Ecchymosis (1) Elevated alanine aminotransferase (ALT) (1) Elevated blood urea nitrogen (BUN) (1) Elevated cholesterol (total) (1) Elevated serum alkaline phosphatase (ALP) (1) Foaming at the mouth (1) Gait abnormality (1) Head bobbing (1) Head shake - ear disorder (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
ANADA: 200592 ANADA: 200604 ANADA: 200702 ANADA: 200709 NADA: 55101 NDC Package: 11695-6991-1 NDC Package: 11695-6992-1 NDC Package: 11695-6993-1 NDC Package: 11695-6994-1 NDC Package: 11695-7007-1 NDC Package: 13744-540-01 NDC Package: 13744-541-01 NDC Package: 13744-542-01 NDC Package: 13744-543-01 NDC Package: 17033-440-07 NDC Package: 17033-440-21 NDC Package: 17033-441-07 NDC Package: 17033-441-21 NDC Package: 17033-442-07 NDC Package: 17033-442-21 NDC Package: 17033-443-07 NDC Package: 17033-443-21 NDC Package: 17033-451-15 NDC Package: 46066-087-17
Package NDC Product NDC Form / Route Status
11695-6991-1 11695 -
11695-6992-1 11695 -
11695-6993-1 11695 -
11695-6994-1 11695 -
11695-7007-1 11695 -
13744-540-01 13744 -
13744-541-01 13744 -
13744-542-01 13744 -
13744-543-01 13744 -
17033-440-07 17033 -
17033-440-21 17033 -
17033-441-07 17033 -
17033-441-21 17033 -
17033-442-07 17033 -
17033-442-21 17033 -
17033-443-07 17033 -
17033-443-21 17033 -
17033-451-15 17033 -
46066-087-17 46066 -
46066-111-60 46066 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

Data Sources & Revision History

Every non-trivial field is expected to include provenance and update timestamps.

Official 8 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. (Official, 2026-02-12)
  • side_effects: Top reported reactions (openFDA): Elevated alanine aminotransferase (ALT), Brain disorder NOS, Bruising, Circling - neurological disorder (see also Behavioural… (Official, 2026-02-12)
  • usage: Clavamox Drops are indicated in the treatment of skin and soft tissue infections such as wounds, abscesses, cellulitis, superficial/juvenile and deep pyoderma … (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Amoxicillin and Clavulanate Potassium for Oral Suspension
RX
Amoxicillin Trihydrate Clavulanate Potassium
Suspension Oral
Cronus Pharma Specialities India Private Ltd. ANADA 200-709 Approved Apr 10, 2024
Amoxicillin and Clavulanate Potassium Tablets
RX
Amoxicillin Trihydrate Clavulanate Potassium
Tablet Oral
Cronus Pharma Specialities India Private Ltd. ANADA 200-702 Approved Dec 12, 2023
Clavamox® Drops
RX
Amoxicillin Trihydrate Clavulanate Potassium
Liquid Oral
Zoetis Inc. NADA 55101 Approved Jan 12, 2023
Clavacillin®
RX
Amoxicillin Trihydrate Clavulanate Potassium
Suspension Oral
Dechra Veterinary Products LLC ANADA 200-604 Approved Jul 25, 2022
Clavacillin®
RX
Amoxicillin Trihydrate Clavulanate Potassium
Tablet Oral
Dechra Veterinary Products LLC ANADA 200-592 Approved Mar 29, 2022

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Dog, No Use Class Stated Or Implied • Cat, No Use Class Stated Or Implied
Composition / specifications
When reconstituted each mL contains 50 mg of amoxicillin as the trihydrate and 12.5 mg of clavulanic acid as the potassium salt.
Dogs
Indication

For the treatment of skin and soft tissue infections such as wounds, abscesses, cellulitis, superficial/juvenile and deep pyoderma due to susceptible strains of the following organisms: ß-lactamase-producing Staphylococcus aureus, non-ß-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., and E. coli. Periodontal infections due to susceptible strains of both aerobic and anaerobic bacteria.

Dosage

The recommended dosage is 6.25 mg/lb (1 mL/10 lb) of body weight twice a day. Skin and soft tissue infections such as abscesses, cellulitis, wounds, superficial/juvenile pyoderma, and periodontal infections should be treated for 5-7 days or for 48 hours after all symptoms have subsided. If no response is seen after 5 days of treatment, therapy should be discontinued and the case reevaluated. Deep pyoderma may require treatment for 21 days; the maximum duration of treatment should not exceed 30 days.

Limitations
Cats
Indication

For the treatment of skin and soft tissue infections such as wounds, abscesses, and cellulitis/dermatitis due to susceptible strains of the following organisms: ß-lactamase-producing Staphylococcus aureus, non-ß-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., E. coli, Pasteurella multocida, and Pasteurella spp. Urinary tract infections (cystitis) due to susceptible strains of E. coli.

Dosage

The recommended dosage is 62.5 mg (1 mL) twice a day. Skin and soft tissue infections such as abscesses and cellulitis/dermatitis should be treated for 5-7 days or 48 hours after all symptoms have subsided, not to exceed 30 days. If no response is seen after 3 days of treatment, therapy should be discontinued and the case reevaluated. Urinary tract infections may require treatment for 10-14 days or longer. The maximum duration of treatment should not exceed 30 days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied • Cat, No Use Class Stated Or Implied
Composition / specifications
62.5 mg tablets (50 mg amoxicillin trihydrate, 12.5 mg clavulanic acid); 125 mg tablets (100 mg amoxicillin trihydrate, 25 mg clavulanic acid); 250 mg tablets (200 mg amoxicillin trihydrate, 50 mg clavulanic acid); 375 mg tablets (300 mg amoxicillin trihydrate, 75 mg clavulanic acid)
Dogs
Indication

For the treatment of skin and soft tissue infections such as wounds, abscesses, cellulitis, superficial/juvenile and deep pyoderma due to susceptible strains of the following organisms: ß-lactamase-producing Staphylococcus aureus, non-ß-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., and E. coli. Periodontal infections due to susceptible strains of both aerobic and anaerobic bacteria.

Dosage

The recommended dosage is 6.25 mg/lb of body weight twice a day.

Limitations
Cats
Indication

For the treatment of skin and soft tissue infections such as wounds, abscesses, and cellulitis/dermatitis due to susceptible strains of the following organisms: ß-lactamase-producing Staphylococcus aureus, non-ß-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., E. coli, and Pasteurella spp. Urinary tract infections (cystitis) due to susceptible strains of E. coli.

Dosage

The recommended dosage is 62.5 mg twice a day.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, Not Breeding Animals • Cat, Not Breeding Animals
Composition / specifications
When reconstituted, each milliliter contains amoxicillin trihydrate equivalent to 50 milligrams of amoxicillin with clavulanate potassium equivalent to 12.5 milligrams of clavulanic acid.
Dogs
Indication

Clavamox Drops are indicated in the treatment of skin and soft tissue infections such as wounds, abscesses, cellulitis, superficial/juvenile and deep pyoderma due to susceptible strains of the following organisms: ß-lactamase-producing Staphylococcus aureus, non-ß-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., and E. coli. Periodontal infections due to susceptible strains of both aerobic and anaerobic bacteria. Clavamox has been shown to be clinically effective for treating cases of canine periodontal disease.

Dosage

The recommended dosage is 6.25 mg/lb (1 mL/10 lb) of body weight twice a day. Skin and soft tissue infections such as abscesses, cellulitis, wounds, superficial/juvenile pyoderma, and periodontal infections should be treated for 5–7 days or for 48 hours after all symptoms have subsided. If no response is seen after 5 days of treatment, therapy should be discontinued and the case reevaluated. Deep pyoderma may require treatment for 21 days; the maximum duration of treatment should not exceed 30 days.

Limitations
Cats
Indication

Clavamox Drops are indicated in the treatment of skin and soft tissue infections such as wounds, abscesses, and cellulitis/dermatitis due to susceptible strains of the following organisms: ß-lactamase-producing Staphylococcus aureus, non-ß-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., E. coli, Pasteurella multocida, and Pasteurella spp. Urinary tract infections (cystitis) due to susceptible strains of E. coli

Therapy may be initiated with Clavamox prior to obtaining results from bacteriological and susceptibility studies. A culture should be obtained prior to treatment to determine susceptibility of the organisms to Clavamox. Following determination of susceptibility results and clinical response to medication, therapy may be reevaluated.

Dosage

The recommended dosage is 62.5 mg (1 mL) twice a day. Skin and soft tissue infections such as abscesses and cellulitis/dermatitis should be treated for 5–7 days or 48 hours after all symptoms have subsided, not to exceed 30 days. If no response is seen after 3 days of treatment, therapy should be discontinued and the case reevaluated. Urinary tract infections may require treatment for 10–14 days or longer. The maximum duration of treatment should not exceed 30 days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied • Cat, No Use Class Stated Or Implied
Composition / specifications
Each mL of suspension contains 50 mg of amoxicillin activity as the trihydrate and 12.5 mg of clavulanic acid activity as the potassium salt.
Dogs
Indication

For the treatment of skin and soft tissue infections such as wounds, abscesses, cellulitis, superficial/juvenile and deep pyoderma due to susceptible strains of the following organisms: ß-lactamase-producing Staphylococcus aureus, non-ß-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., and E. coli. Periodontal infections due to susceptible strains of both aerobic and anaerobic bacteria.

Dosage

The recommended dosage is 6.25 mg/lb (1 mL/10 lb) of body weight twice a day. Skin and soft tissue infections such as abscesses, cellulitis, wounds, superficial/juvenile pyoderma, and periodontal infections should be treated for 5-7 days or for 48 hours after all symptoms have subsided. If no response is seen after 5 days of treatment, therapy should be discontinued and the case reevaluated. Deep pyoderma may require treatment for 21 days; the maximum duration of treatment should not exceed 30 days.

Limitations
Cats
Indication

For the treatment of skin and soft tissue infections such as wounds, abscesses, and cellulitis/dermatitis due to susceptible strains of the following organisms: ß-lactamase-producing Staphylococcus aureus, non-ß-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., E. coli, Pasteurella multocida, and Pasteurella spp. Urinary tract infections (cystitis) due to susceptible strains of E. coli.

Dosage

The recommended dosage is 62.5 mg (1 mL) twice a day. Skin and soft tissue infections such as abscesses and cellulitis/dermatitis should be treated for 5-7 days or 48 hours after all symptoms have subsided, not to exceed 30 days. If no response is seen after 3 days of treatment, therapy should be discontinued and the case reevaluated. Urinary tract infections may require treatment for 10-14 days or longer. The maximum duration of treatment should not exceed 30 days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied • Cat, No Use Class Stated Or Implied
Composition / specifications
62.5 mg (50 mg amoxicillin, 12.5 mg clavulanic acid)
125 mg (100 mg amoxicillin, 25 mg clavulanic acid)
250 mg (200 mg amoxicillin, 50 mg clavulanic acid)
375 mg (300 mg amoxicillin, 75 mg clavulanic acid)
Cats
Indication

For the treatment of skin and soft tissue infections such as wounds, abscesses, and cellulitis/dermatitis due to susceptible strains of the following organisms: ß-lactamase-producing Staphylococcus aureus, non-ß-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., E. coli, and Pasteurella spp. Urinary tract infections (cystitis) due to susceptible strains of E. coli.

Dosage

The recommended dosage is 62.5 mg twice a day.Skin and soft tissue infections such as abscesses and cellulitis/dermatitis should be treated for 5-7 days or for 48 hours after all symptoms have subsided, not to exceed 30 days. If no response is seen after 3 days of treatment, therapy should be discontinued and the case reevaluated.Urinary tract infections may require treatment for 10-14 days or longer. The maximum duration of treatment should not exceed 30 days.

Limitations

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Dogs
Indication

For the treatment of skin and soft tissue infections such as wounds, abscesses, cellulitis, superficial/juvenile and deep pyoderma due to susceptible strains of the following organisms: ß-lactamase-producing Staphylococcus aureus, non-ß-lactamase- producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., and E. coli. Periodontal infections due to susceptible strains of both aerobic and anaerobic bacteria. Amoxicillin trihydrate and clavulanate potassium tablets have been shown to be clinically effective for treating cases of canine periodontal disease.

Dosage

The recommended dosage is 6.25 mg/lb of body weight twice a day.Skin and soft tissue infections such as abscesses, cellulitis, wounds, superficial/juvenile pyoderma, and periodontal infections should be treated for 5-7 days or for 48 hours after all symptoms have subsided. If no response is seen after 5 days of treatment, therapy should be discontinued and the case reevaluated. Deep pyoderma may require treatment for 21 days; the maximum duration of treatment should not exceed 30 days.

Limitations

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Official Documents (FDA)

Direct links to FDA-hosted PDFs and SPL packages (when available).

Documents
  • Summary

    For the treatment of the following:

    Dogs: Skin and soft tissue infections such as wounds, abscesses, cellulitis, superficial/juvenile and deep pyoderma due to susceptible strains of the following organisms: ß-lactamase-producing Staphylococcus aureus, non-ß-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., and E. coli. Periodontal infections due to susceptible strains of both aerobic and anaerobic bacteria.

    Cats: Skin and soft tissue infections such as wounds, abscesses, and cellulitis/dermatitis due to susceptible strains of the following organisms: ß-lactamase-producing Staphylococcus aureus, non-ß-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., E. coli, Pasteurella multocida, and Pasteurella spp. Urinary tract infections (cystitis) due to susceptible strains of E. coli.

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    Amoxicillin and Clavulanate Potassium Tablets are indicated in the treatment of:

    Dogs: Skin and soft tissue infections such as wounds, abscesses, cellulitis, superficial/juvenile and deep pyoderma due to susceptible strains of the following organisms: β-lactamase-producing Staphylococcus aureus, non-β-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., and E. coli. Periodontal infections due to susceptible strains of both aerobic and anaerobic bacteria.

    Cats: Skin and soft tissue infections such as wounds, abscesses, and cellulitis/dermatitis due to susceptible strains of the following organisms: β-lactamase-producing Staphylococcus aureus, non-β-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., E. coli, and Pasteurella spp. Urinary tract infections (cystitis) due to susceptible strains of E. coli.

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    For the treatment of:

    Dogs: Skin and soft tissue infections such as wounds, abscesses, cellulitis, superficial/juvenile and deep pyoderma due to susceptible strains of the following organisms: β-lactamase-producing Staphylococcus aureus, non-β-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., and E. coli. Periodontal infections due to susceptible strains of both aerobic and anaerobic bacteria.

    Cats: Skin and soft tissue infections such as wounds, abscesses, and cellulitis/dermatitis due to susceptible strains of the following organisms: β-lactamase-producing Staphylococcus aureus, non-β-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., E. coli, Pasteurella multocida, and Pasteurella spp. Urinary tract infections (cystitis) due to susceptible strains of E. coli.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For the treatment of: Dogs: Skin and soft tissue infections such as wounds, abscesses, cellulitis, superficial/juvenile and deep pyoderma due to susceptible strains of the following organisms: ß-lactamase-producing   Staphylococcus aureus, non- ß-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp. and E. coli. Periodontal infections due to susceptible strains of both aerobic and anaerobic bacteria. Amoxicillin trihydrate and clavulanate potassium tablets have been shown to be clinically effective for treating cases of canine periodontal disease. Cats: Skin and soft tissue infections such as wounds, abscesses, and cellulitis/dermatitis due to susceptible strains of the following organisms: ß-lactamase-producing   Staphylococcus aureus, non- ß-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., E. coli and  Pasteurella spp. Urinary tract infections (cystitis) due to susceptible strains of  E. coli.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Usage

Clavamox Drops are indicated in the treatment of skin and soft tissue infections such as wounds, abscesses, cellulitis, superficial/juvenile and deep pyoderma due to susceptible strains of the following organisms: ß-lactamase-producing Staphylo coccus aureus , non- ß -lactamase-producing Staphylococcus aureus , Staphylococcus spp., Streptococcus spp., and E. coli . Periodontal infections due to susceptible strains of both aerobic and anaerobic bacteria. Clavamox has been shown to be clinically effective for treating cases of canine periodontal disease. Clavamox Drops are indicated in the treatment of skin and soft tissue infections such as wounds, abscesses, and cellulitis/dermatitis due to susceptible strains of the following organisms: ß-lactamase-producing Staphylococcus aureus , non-ß-lactamase-producing Staphylococcus aureus , Staphylococcus spp., Streptococcus spp., E. coli , Pasteurella multocida , and Pasteurella spp. Urinary tract infections (cystitis) due to susceptible strains of E. coli . Therapy may be initiated with Clavamox prior to obtaining results from bacteriological and susceptibility studies. A culture should be obtained prior to treatment to determine susceptibility of the organisms to Clavamox. Following determination of susceptibility results and clinical response to medication, therapy may be reevaluated. For the treatment of skin and soft tissue infections such as wounds, abscesses, and cellulitis/dermatitis due to susceptible strains of the following organisms: ß-lactamase-producing Staphylococcus aureus, non-ß-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., E. coli, and Pasteurella spp. Urinary tract infections (cystitis) due to susceptible strains of E. coli.

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Side Effects

No approved side-effect narrative is linked yet.

openFDA reaction signals are available for Dog 8 and Cat 38 (view top reported reactions).

Top Reported Reactions (openFDA)

Aggregated reaction terms from FDA openFDA reports (not verified; does not prove causation).

Dog
Neurologic
Circling - neurological disorder (1)
Other
Elevated alanine aminotransferase (2) Brain disorder NOS (1) Bruising (1) Distension of abdomen (1) Ecchymosis (1) Elevated blood urea nitrogen (1) Elevated cholesterol (1)
Cat
Digestive
Diarrhea (1) Diarrhea (1) Diarrhea (1) Diarrhea (1) Diarrhea (1) Diarrhea (1) Diarrhea (1) Vomiting (1) Vomiting (1) Vomiting (1) Vomiting (1) Vomiting (1) Vomiting (1)
Neurologic
Unsteady walking (ataxia) (1)
Other
Color, Abnormal (1) Color, Abnormal (1) Color, Abnormal (1) Color, Abnormal (1) Color, Abnormal (1) Color, Abnormal (1) Color, Abnormal (1) Gait abnormality (1) Head shake - ear disorder (1) Not eating (1) Odor, Abnormal (1) Odor, Abnormal (1) Odor, Abnormal (1) Odor, Abnormal (1) Odor, Abnormal (1) Odor, Abnormal (1) Odor, Abnormal (1) Respiratory tract infection NOS (1) Seal, Abnormal (1) Seal, Abnormal (1) Seal, Abnormal (1) Seal, Abnormal (1) Seal, Abnormal (1) Seal, Abnormal (1)

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Cat, Cat (unknown), Unknown, 13 year, 3.629 kilogram • Drug: MSK, Suspension, Oral, Dose: 63 Milligram per ml, Frequency: 2 per day • Reactions: Color, Abnormal, Odor, Abnormal, Diarrhea, Vomiting, Seal, Abnormal • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-048608
  • Serious AE: No
  • Treated For AE: No
  • Sex: Unknown
  • Age: 13.00 Year
  • Weight: 3.629 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Suspension
  • Dose: 63 Milligram per ml
  • Frequency: 2 per day
Reactions Reported:
Color, Abnormal Odor, Abnormal Diarrhea Vomiting Seal, Abnormal
Outcomes: Outcome Unknown

Cat, Bengal, Female, 6.5 year, 3.86 kilogram • Drug: MSK • Reactions: Unsteady walking (ataxia), Head shake - ear disorder, Respiratory tract infection NOS, Unable to jump, Not eating… • Outcome: Recovered with Sequela

  • Report ID: USA-USFDACVM-2025-US-006774
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 6.50 Year
  • Weight: 3.860 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
Reactions Reported:
Unsteady walking (ataxia) Head shake - ear disorder Respiratory tract infection NOS Unable to jump Not eating Gait abnormality
Outcomes: Recovered with Sequela

Dog, ['Pit Bull', 'Retriever - Golden'], Female, 9 year, 16 kilogram • Drug: MSK • Reactions: Foaming at the mouth, Restlessness, Not sleeping, Pain NOS, Brain disorder NOS… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2024-US-017895
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 9.00 Year
  • Weight: 16.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
Reactions Reported:
Foaming at the mouth Restlessness Not sleeping Pain NOS Brain disorder NOS Neoplasia NOS Pacing Circling - neurological disorder Head bobbing Thrombocytopenia Leucocytosis NOS Lymphopenia Distension of abdomen Meningitis Pyometra Elevated blood urea nitrogen Elevated alanine aminotransferase Elevated serum alkaline phosphatase Onset of lactation Elevated cholesterol Less social Large platelets
Outcomes: Outcome Unknown

Dog, Shepherd Dog - German, Female, 2 year, 30.6 kilogram • Drug: MSK, Oral, Dose: 1 tablet per unknown, Frequency: 12 per hour • Reactions: Vomiting, Pinnal reddening, Hypoglycaemia, Elevated alanine aminotransferase, Ecchymosis… • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2017-US-055965
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 2.00 Year
  • Weight: 30.600 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Dose: 1 tablet per unknown
  • Frequency: 12 per hour
Reactions Reported:
Vomiting Pinnal reddening Hypoglycaemia Elevated alanine aminotransferase Ecchymosis Skin petechiae Bruising
Outcomes: Recovered/Normal

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

Share Your Thoughts

Let others know your experience or advice regarding this medication.

This medication has not been reviewed by a veterinarian yet.